• 제목/요약/키워드: queen

검색결과 518건 처리시간 0.024초

Manual Contouring Based Volumetric Evaluation for Colorectal Cancer with Liver Limited Metastases: A Comparison with RECIST

  • Fang, W.J.;Lam, K.O.;Ng, S.C.Y.;Choi, C.W.;Kwong, D.L.W.;Zheng, S.S.;Lee, V.H.F.
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권7호
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    • pp.4151-4155
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    • 2013
  • Background: To compare response evaluation criteria in solid tumours (RECIST) and volumetric evaluation (VE) for colorectal cancer with liver-limited metastasis. Patients and Methods: VE of liver metastases was performed by manual contouring before and after chemotherapy on 45 pairs of computed tomography (CT) images in 36 patients who suffered from metastatic colorectal cancer (mCRC) with liver metastasis only. Cohen kappa was used to compare the agreement between VE and RECIST. Pearson correlation was performed for their comparison after cubic root transformation of the aggregate tumor volumes. Logistic regression was done to identify clinical and radiographic factors to account for the difference which may be predictive in overall response (OR). Results: There were 16 partial response (PR), 23 stable disease (SD) and 6 progressive disease (PD) cases with VE, and 14 PR, 23 SD and 8 PD with RECIST. VE demonstrated good agreement with RECIST (${\chi}$=0.779). Discordant objective responses were noted in 6 pairs of comparisons (13.3%). Pearson correlation also showed excellent correlation between VE and RECIST ($r^2$=0.966, p<0.001). Subgroup analysis showed that VE was in slightly better agreement with RECIST for enlarging lesions than for shrinking lesions ($r^2$=0.935 and $r^2$=0.780 respectively). No factor was found predictive of the difference in OR between VE and RECIST. Conclusions: VE exhibited good agreement with RECIST. It might be more useful than RECIST in evaluation shrinking lesions in cases of numerous and conglomerate liver metastases.

Marie Antoinette의 초상화를 통해 본 18세기 후기 여성 복식의 변화와 계몽주의 사상 - 1770-1793을 중심으로 - (The Transition of Late 18th Century Women's Costume and Enlightenment, with Reviewing the Portraiture of Marie Antoinette - Focused on 1770-1793 -)

  • 배수정
    • 복식
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    • 제62권1호
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    • pp.120-136
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    • 2012
  • This thesis takes an aim to investigate the relationship between the costume and enlightenment ideology by studying the change of costume, and reviewing the portraiture of Queen Marie Antoinette. The method of this research is to select the 29 pieces among the portraitures from 1770 to 1793, and to analyze the headdress, shape of robes and ornaments. The results are as follows. The first period(1770-1774): The costume in this period of Dauphin of France is described as vivid, and simple like her characters, and also represents her active lifestyle. The ideology of equality between the two sexes from the enlightenment slightly influence the costumes seen inside the portrait of Dauphin. The second period (1775-1779): This is the early period of the Queen's enthronement and also before her childbirth. The relatively small number of portraits showed her as an authoritative figure because her skirts were expanded with huge panier, the waist were tightened with corset, and her headdress was enlarged. Thus, this period could not be defined as the one of enlightenment philosophies in light of the persistent unsanitary construction of costumes distorting the body. The third period(1780-1789): There are many portraits depicting the Queen and her children. It is noteworthy that the English style picturesque garden was illustrated as a background while the costume was simple and sanitary, both being affected by the enlightenment. The last period(1789-1793): This is the period between the French revolution and the death of the Queen. The form of costumes was transformed into the neoclassic style, headdress was reduced in size, and was simplified as a result of complete change of costume for the enlightenment. This research is to be interpreted as a tool of study about the relationship of costume, society and ideological streams and also be a means of elucidating the contemporary times in view of the past ones.

저장(貯藏)에 따른 감자의 Glycoalkaloid의 변화(變化) (Change in Glycoalkaloid of Potatoes during Storage)

  • 황춘선;이성우
    • 한국식품과학회지
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    • 제16권4호
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    • pp.388-391
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    • 1984
  • Irish Cobbler와 May Queen의 두품종(品種)의 감자를 $1^{\circ}$$20^{\circ}C$에 저장(貯藏)하여 피층부(皮層部) 및 수질부(髓質部)의 glycoalkaloid ($({\alpha}-chaconine$, ${\alpha}-solanine$) 함량(含量)의 변화(變化)를 조사(調査) 검토(檢討)한 결과는 다음과 같다. 감자 괴경(塊莖)을 $20^{\circ}C$구(區)에서 저장 하였을 때 두품종(品種) 다같이 맹아(萌芽)에 따라 피층부(皮層部)의 ${\alpha}-chaconine$${\alpha}-solanine$함량(含量)이 증가(增加)하였고 그 증가(增加)의 정도(程度)는 May Queen에 있어서 보다 현저(顯著)하였다. $1^{\circ}C$구(區)의 피층부(皮層部)에서는 두품종(品種) 다같이 외관상(外觀上)의 변화(變化)가 보이지 않은 저장기간 중에도 glycoalkaloid가 증가(增加)하는 것이 확인(確認)되었다. 수질부(髓質部)에 있어서는 두품종(品種) 다같이 저장에 따라 소량의 ${\alpha}-chaconine$이 약간 검출되었으나, ${\alpha}-solanine$은 양온도구(兩溫度區)에서 검출(檢出)되지 않았다.

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엘리자베스 1세의 초상화에 나타난 16세기 러프 칼라와 러프 커프스의 미시적 변화 연구 (A Study on the Exquisite Revolution of the 16th Century Ruff Collar and Ruff Cuffs in the Portraitures of Queen Elizabeth I)

  • 배수정
    • 한국의류학회지
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    • 제35권2호
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    • pp.167-180
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    • 2011
  • The portraits created in the age of Queen Elizabeth I show a very exquisite description about the ruff collar and cuffs representing the notable evolution of periodical costumes from a detailed viewpoint. This thesis analyzes the ruff collar and cuffs of the portraits of Queen Elizabeth I. The method used selects 32 pieces from the portraits of Queen Elizabeth I that are considered excellent depictions of a ruff collar and cuffs, to investigate size, form and decorations. Conclusively, the ruff collar tends to be extremely enlarged and thickened (coinciding with the development of glue) while the cuffs denote the aspect of double cuffs coupled with the turn-back cuffs without a change in size. These traits were widely shown from 1585 to 1587, while after 1588 the ruff cuffs completely disappeared in the portraits of Elizabeth I. At the same time, the change of a ruff collar was remarkable, the collar being in the erect position behind the head (with the use of supporters), of a consistent thickness and decoration of elaborate lace. During the transition period from the $16^{th}$ century to the $17^{th}$ century the earliest change was in cuffs followed by collars. This research is a helpful guide to detect the relatively exact date of portraits not definitively identified in the latter part of the $16^{th}$ century and to observe the microscopic evolution of costumes in the latter part of the $16^{th}$ century.

Interfacial modulus mapping of layered dental ceramics using nanoindentation

  • Theocharopoulos, Antonios L;Bushby, Andrew J;P'ng, Ken MY;Wilson, Rory M;Tanner, K Elizabeth;Cattel, Michael J
    • The Journal of Advanced Prosthodontics
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    • 제8권6호
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    • pp.479-488
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    • 2016
  • PURPOSE. The aim of this study was to test the modulus of elasticity (E) across the interfaces of yttria stabilized zirconia (YTZP) / veneer multilayers using nanoindentation. MATERIALS AND METHODS. YTZP core material (KaVo-Everest, Germany) specimens were either coated with a liner (IPS e.max ZirLiner, Ivoclar-Vivadent) (Type-1) or left as-sintered (Type-2) and subsequently veneered with a pressable glass-ceramic (IPS e.max ZirPress, Ivoclar-Vivadent). A $5{\mu}m$ (nominal tip diameter) spherical indenter was used with a UMIS CSIRO 2000 (ASI, Canberra, Australia) nanoindenter system to test E across the exposed and polished interfaces of both specimen types. The multiple point load - partial unload method was used for E determination. All materials used were characterized using Scanning Electron Microscopy (SEM) and X - ray powder diffraction (XRD). E mappings of the areas tested were produced from the nanoindentation data. RESULTS. A significantly (P<.05) lower E value between Type-1 and Type-2 specimens at a distance of $40{\mu}m$ in the veneer material was associated with the liner. XRD and SEM characterization of the zirconia sample showed a fine grained bulk tetragonal phase. IPS e-max ZirPress and IPS e-max ZirLiner materials were characterized as amorphous. CONCLUSION. The liner between the YTZP core and the heat pressed veneer may act as a weak link in this dental multilayer due to its significantly (P<.05) lower E. The present study has shown nanoindentation using spherical indentation and the multiple point load - partial unload method to be reliable predictors of E and useful evaluation tools for layered dental ceramic interfaces.

산란촉진자를 이용한 호박벌(Bombus ignitus)의 산란성 및 봉세발달 개선효과 (Facilitating Effects of Helpers on Oviposition and Colony Development of Bumblebee Queen, Bombus ignitus)

  • 윤형주;김삼은
    • 한국응용곤충학회지
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    • 제41권4호
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    • pp.239-245
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    • 2002
  • 갓 우화한 호박벌 및 서양뒤영벌 일벌, 우화 후 10-20일 된 서양뒤영벌 일벌, 서양뒤영벌 일벌과 수벌의 고치, 건조고치, 갓 우화한 꿀벌 일벌, 산란컵을 교미직후의 호박벌(Bombus ignitus)여왕벌 사육상자에 투입하여 산란촉진자로서의 효과를 비교 조사하였다. 갓 우화한 호박벌과 서양뒤영벌의 일벌을 산란촉진자로 사용한 경우 산란율이 각각 92%와 88%로 높았고, 생고치를 투입했을 경우에도 산란율이 60%이상으로 산란촉진자의 효과가 인정되었다. 우화 후 10일이 경과한 나이든 호박벌과 서양뒤영벌의 일벌이더라도 탄산가스에 30분간 접촉시킨 후 산란촉진자로 투입했을 경우에는 산란율, 봉군형성율, 신여왕벌 출현율 등 봉세발달이 갓 우화한 일벌을 산란촉진자로 사용하였을 경우의 봉세발달과 유사한 성적을 보여 우화한지 초래된 일벌도 산란촉진자로서의 가치가 있음을 확인하였다. 그러나 번데기를 죽인 건조고치, 꿀벌 일벌, 산란컵을 산란촉진자로 사용한 경우에는 산란촉진효과가 인정되지 않았다. 산란촉진효과가 높았던 서양뒤영벌 일벌을 산란촉진자로 사용할 경우, 적정 투입수를 알아보기 위해 갓 우화한 일벌을 시험구당 1마리에서 4마리까지 투입하였다. 그 결과, 산란촉진자를 1마리 투입한 구보다 2마리 이상 투입한 시험구의 봉세발달이 우수하였으며, 2마리 이상 투입한 시험구 간의 봉세발달에는 차이가 없었다.

에메리개미 (Vollenhovia emeryi Wheeler)의 날개이형체의 유전체 크기 추정 (Genome Size Estimation of the Two Wing Morphs of Vollenhovia emeryi (Hymenoptera: Myrmicinae))

  • 노푸름;박소연;최재천;정길상
    • 한국응용곤충학회지
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    • 제57권4호
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    • pp.317-322
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    • 2018
  • 에메리개미는 여왕개미와 수개미가 유전적으로 복제되어 번식한다고 알려져 있으며, 여왕개미의 날개형태가 장시형과 단시형으로 나타난다. 장시형은 정상적인 날개형태이고, 이보다 짧은 날개형태는 단시형이라고 한다. 장시형과 단시형 모두 한 종으로 취급되지만, 두 가지 점에서 종지위에 대한 조사가 필요하다. 첫째, 자연 상태에서는 두 날개형이 함께 발견되지 않고, 둘째, 날개형이 육안으로 뚜렷하게 구분된다. 또한 복제되어 번식한 여왕개미가 단수체인지 배수체인지 조사가 필요하다. 따라서 우리는 본 연구에서 에메리개미 유전체 크기를 추정하여 두 날개형은 동종이며, 여왕개미는 배수체임을 확인하였다.

제국주의, 민족주의, 그리고 휴머니즘 -『적색의 왕비』와 『아리랑 노래』의 비교 연구 (Imperialism, Nationalism, and Humanism: A Comparative Study of The Red Queen and Song of Ariran)

  • 박은경
    • 영미문화
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    • 제9권1호
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    • pp.239-272
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    • 2009
  • Our investigation of the intricate relationship among nationalism, humanism, and imperialism begins from reading Song of Ariran, the auto/biography of Kim San recorded by Nym Wales, together with Margaret Drabble's fictional adaptation of Lady Hong's autobiography, The Memoirs of Lady $Hyegy{\breve{o}}ng$, in her novel The Red Queen, in which the story of Barbara Halliwell, a modern female envoy of Lady Hong, is interweaved with Lady Hong's narrative. In spite of their being seemingly disparate texts, Song of Ariran and The Red Queen are comparable: they are written by Western female writers who deal with Koreans, along with the Korean history and culture. Accordingly, both works cut across the boundary of fiction and fact, imagination and history, and the East and the West. In the age of globalization, Western women writing (about) Korea and Koreans traversing the historical and cultural limits inevitably engage us in post-colonial discussions. Despite the temporal differences--If Song of Ariran handles with the historical turmoils of the 1930s Asia, mostly surrounding Kim San's activities as a nationalist, The Red Queen is written by a twenty-first century British woman writer whose international interest grapples with the eighteenth-century Korean Crown Princess' spirit in order to reinscribe a story of Korean woman's within the contemporary culture--, both works appeal to the humanistic perspective, advocating the universal human beings' values transcending the historical and national limitations. While this sort of humanistic approach can provide sympathy transcending time and space, this 'idealistic' process can be problematic because the Western writers's appropriation of Korean culture and its history can easily reduce its particularities to comprehensive generalization, without giving proper names to the Korean history and culture. Nonetheless, the Western female writers' attempt to find a place of 'contact' is valuable since it opens a possibility of having meaningful communications between minor culture and dominating culture. Yet, these female writers do not seem to absolutely cross the border of race, gender, and culture, which leaves us to realize how difficult it is to reach a genuine understanding with what is different from mine even in these 'universal' narratives.

Chemical signalling within the rumen microbiome

  • Katie Lawther;Fernanda Godoy Santos;Linda B Oyama;Sharon A Huws
    • Animal Bioscience
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    • 제37권2_spc호
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    • pp.337-345
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    • 2024
  • Ruminants possess a specialized four-compartment forestomach, consisting of the reticulum, rumen, omasum, and abomasum. The rumen, the primary fermentative chamber, harbours a dynamic ecosystem comprising bacteria, protozoa, fungi, archaea, and bacteriophages. These microorganisms engage in diverse ecological interactions within the rumen microbiome, primarily benefiting the host animal by deriving energy from plant material breakdown. These interactions encompass symbiosis, such as mutualism and commensalism, as well as parasitism, predation, and competition. These ecological interactions are dependent on many factors, including the production of diverse molecules, such as those involved in quorum sensing (QS). QS is a density-dependent signalling mechanism involving the release of autoinducer (AIs) compounds, when cell density increases AIs bind to receptors causing the altered expression of certain genes. These AIs are classified as mainly being N-acyl-homoserine lactones (AHL; commonly used by Gram-negative bacteria) or autoinducer-2 based systems (AI-2; used by Gram-positive and Gram-negative bacteria); although other less common AI systems exist. Most of our understanding of QS at a gene-level comes from pure culture in vitro studies using bacterial pathogens, with much being unknown on a commensal bacterial and ecosystem level, especially in the context of the rumen microbiome. A small number of studies have explored QS in the rumen using 'omic' technologies, revealing a prevalence of AI-2 QS systems among rumen bacteria. Nevertheless, the implications of these signalling systems on gene regulation, rumen ecology, and ruminant characteristics are largely uncharted territory. Metatranscriptome data tracking the colonization of perennial ryegrass by rumen microbes suggest that these chemicals may influence transitions in bacterial diversity during colonization. The likelihood of undiscovered chemicals within the rumen microbial arsenal is high, with the identified chemicals representing only the tip of the iceberg. A comprehensive grasp of rumen microbial chemical signalling is crucial for addressing the challenges of food security and climate targets.

Measuring displacements of a railroad bridge using DIC and accelerometers

  • Hoag, Adam;Hoult, Neil A.;Take, W. Andy;Moreu, Fernando;Le, Hoat;Tolikonda, Vamsi
    • Smart Structures and Systems
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    • 제19권2호
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    • pp.225-236
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    • 2017
  • Railroad bridges in North America are an integral but aging part of the railroad network and are typically only monitored using visual inspections. When quantitative information is required for assessment, railroads often monitor bridges using accelerometers. However without a sensor to directly measure displacements, it is difficult to interpret these results as they relate to bridge performance. Digital Image Correlation (DIC) is a non-contact sensor technology capable of directly measuring the displacement of any visible bridge component. In this research, a railroad bridge was monitored under load using DIC and accelerometers. DIC measurements are directly compared to serviceability limits and it is observed that the bridge is compliant. The accelerometer data is also used to calculate displacements which are compared to the DIC measurements to assess the accuracy of the accelerometer measurements. These measurements compared well for zero-mean lateral data, providing measurement redundancy and validation. The lateral displacements from both the accelerometers and DIC at the supports were then used to determine the source of lateral displacements within the support system.