• Title/Summary/Keyword: quantitative inheritance

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Identification of Quantitative Trait Loci for Resistance to Soybean Cyst Nematode Race 14 (콩시스트 선충 race14에 대한 저항성 유전자좌 구명)

  • Choi, In-Soo;Kim, Yong-Chul
    • Journal of Life Science
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    • v.13 no.4
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    • pp.375-382
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    • 2003
  • A direct and precise explanation of soybean resistance to soybean cyst nematode will be possible only when the individual gene(s) involved in the resistance are tagged. This study was conducted, (1) to identify and localize quantitative trait loci for resistance to soybean cyst nematode race 14 on RAPD map, (2) to identify the magnitude and mode of inheritance for each quantitative trait loci, and (3) to identify the best combinations of quantitative trait loci for resistance to soybean cyst nematode race 14. Thirty markers (29 RAPD and 1 RFLP) showed significant association with resistance to soybean cyst nematode race 14. From MAPMAKER/QTL analysis, we identified two regions (linkage group C-7 and linkage group C-9) for resistance to soybean cyst nematode .ace 14. The first quantitative trait loci that was localized at 6.0 cM from $H06^1$ on linkage group C-7 showed a dominant inheritance mode. However, we can not exclude the possibility of additive inheritance mode. The second quantitative trait loci that was localized between $B15^2$ and $E01^1$ on linkage group C-9 also showed a dominant mode of inheritance. One pair of flanking markers ($H06^1$ and $H06^2$) and B15$^2$ were used for multiple regression analysis. Marker combination that included 2 markers, $B15^2$ and $H06^1$, explained the highest total variance (22.9%) for resistance to soybean cyst nematode race 14. Further localization of genes for resistance to soybean cyst nematode race 14 and examination of interaction between quantitative trait loci will accelerate the exploitation of resistance to soybean cyst nematode.

A Heuristic Metric for Measuring Complexity of Class Inheritance Structures (클래스 상속구조에 대한 경험적 복잡성 척도)

  • Chung, Hong;Kim, Tae-Sik
    • Journal of the Korean Institute of Intelligent Systems
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    • v.12 no.4
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    • pp.328-333
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    • 2002
  • The deeper the hierarchy of a inheritance structure is, the better the reusability of the structure is, but the more difficult the understandability and the maintainability of it is. On the contrary, the shallower the hierarchy is, the worse the abstraction of the inheritance structure is, but the better the understandability and modifiability of it is. Therefore, it is to be desired that a deep hierarchy of a inheritance structure should be split to be shallow for the maintainability of a system. This paper proposed a complexity metric that is based on DIT and NOC of Chidamber and Kemerer, and solved the ambiguity of the metrics of them, which was pointed out by Li. The metric is a simple and heuristic one for measuring the complexity of class inheritance structures by considering the number of ancestor classes and descendant classes and the depth of inheritance hierarchy. This provides a quantitative information for assessing the complexity of a inheritance structure in splitting it.

Detection of Mendelian and Parent-of-origin Quantitative Trait Loci for Meat Quality in a Cross between Korean Native Pig and Landrace

  • Choi, B.H.;Lee, Y.M.;Alam, M.;Lee, J.H.;Kim, T.H.;Kim, K.S.;Kim, J.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.12
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    • pp.1644-1650
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    • 2011
  • This study was conducted to detect quantitative trait loci (QTL) affecting meat quality in an $F_2$ reference population of Korean native pig and Landrace crossbreds. The three-generation mapping population was generated with 411 progeny from 38 $F_2$ full-sib families, and 133 genetic markers were used to produce a sex-average map of the 17 autosomes. The data set was analyzed using least squares Mendelian and parent-of-origin interval-mapping models. Lack-of-fit tests between models were used to characterize the QTL for mode of gene expressions. A total of 10 (32) QTL were detected at the 5% genome (chromosome)-wise level for the analyzed traits. Of the 42 QTL detected, 13 QTL were classified as Mendelian, 10 as paternal, 14 as maternal, and 5 as partial expressed QTL, respectively. Among the QTL detected at 5% genome-wise level, four QTL had Mendelian mode of inheritance on SSCs 5, 10, 12, and 13 for cooking loss, drip loss, crude lipid and crude protein, respectively; two QTL maternal inheritance for pH at 24-h and shear force on SSC11; three QTL paternal inheritance for CIE b and Hunter b on SSC9 and for cooking loss on SSC15; and one QTL partial expression for crude ash on SSC13, respectively. Most of the Mendelian QTL (9 of 13) had a dominant mode of gene action, suggesting potential utilization of heterosis for genetic improvement of meat quality within the cross population via marker-assisted selection.

Inheritance Analysis of Giant Embryo Mutation Induced by T-DNA Insertion in Rice

  • Qin, Yang;Kim, Suk-Man;Park, Hee-Yeon;Sohn, Jae-Keun
    • Korean Journal of Breeding Science
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    • v.41 no.1
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    • pp.9-15
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    • 2009
  • Recently, giant embryonic rice and functional rice food are preferred by more consumers, which are attributed to the fact that the embryo has high concentrations of essential amino acids, fatty acids, and vitamins relative to other parts of rice grains. In this report, the heredity and stability of giant embryo mutations in successive generations were analyzed regarding a giant embryonic line, 'P47', induced by T-DNA insertion and a $F_2$ population from a cross between 'P47' and 'Junam'. The mutant lines with increases of 1.5, 1.7 and 1.8 times on embryo length, width and 100-embryo weight to those of the control showed stable inheritance across three generations. The continuous frequency distributions of embryo size in the $F_2$ population showed that the embryo size is a quantitative trait of polygene controlled. In addition, wide range of transgressive segregations of six traits affecting embryo size confirmed exchange of genetic materials and recombination between genes controlling embryo size. Five giant embryo mutant lines selected from the $F_2$ population will be used for artificial selection and improvement of giant embryonic varieties.

Studies on the Degree of Genetic Divergence for Different Quantitative Traits Between Paremntal Lines of Silkworm, Bombyx mori L., Hybrids

  • Petkov, Naoum;Grekov, Dimitar;Ramnali, Paraskevi
    • International Journal of Industrial Entomology and Biomaterials
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    • v.2 no.1
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    • pp.79-81
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    • 2001
  • A study was conducted to establish the degree of genetic divergence between different hybrid forms and rearing conditions through estimation of the minimum number of genes (allelic pairs) differentiating parents in terms of specific quantitative traits. It was established that the minimum gene numbers differentiating parental lines in the inheritance of cocoon was 1, of cocoon shell weight- between 1 and 2, and of silk filament length- between 2 and 3. The variability in the specific genetic parameter could be explained by the reliability of the statistical-and-genetic method used and the expression of genes affecting the formation of each of the characters tested. Gene expression, in its turns is conditioned both by the gene interaction within the genotypes and the different genotype response to environmental change. To go deep in the problem, experiments should be conducted under strictly controlled conditions, reducing the mathematical-and-genetic analysis to a physiological levels and hence to analyse the genetic nature of the specific quantitative character formation and its genetic control.

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Study on the Inheritance of Powdery Mildew Resistance in Common Wheat (밀의 흰가루병 저항성의 유전에 관한 연구)

  • Young-Am Chae
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.24 no.4
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    • pp.35-37
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    • 1979
  • To investigate the genetic system in resistance to powdery mildew winter wheat cultivar Diplomat which has stable field resistance was crossed with high yielding susceptible winter type Caribo and Hayman's generation mean analysis technique was employed. Mildewing rate on flag-leaf at both heading-flowering and ripe stages were recorded according to lame's quantitative scale. The result indicated that additive gene effect was more important and significant role in the inheritance of resistance while dominant gene effect was minimum, and digenic interations were absent. Narrow sense heritability of resistance at ripe stage was higher than that of heading-flowering stage.

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Challenges for QTL Analysis in Crops

  • Long, Yan;Zhang, Chunyu;Meng, Jinling
    • Journal of Crop Science and Biotechnology
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    • v.11 no.1
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    • pp.7-12
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    • 2008
  • Quantitative trait loci, a genetic concept for explaining the inheritance of non-Mendelian traits in 1940s, have been realized as particular fragments of chromosome even unique genes in most crops in 21st century. However, only very a small portion of QTL has been screened out by geneticists comparing to a great number of genes underneath the quantitative traits. These identified QTL even have been seldom used into breeding program because crop breeders may not find the QTL in their breeding populations in their field station. Several key points will be proposed to meet the challenges of QTL analysis today: a fine mapping population and the related reference genetic map, QTL evaluation in multiple environments, recognizing real QTL with small genetic effect, map integration.

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Inheritance and Heritability of Telomere Length in Chicken (닭 텔로미어 길이의 유전력 추정과 유전 전이 양상)

  • Park, Dan Bi;Sohn, Sea Hwan
    • Korean Journal of Poultry Science
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    • v.41 no.3
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    • pp.217-225
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    • 2014
  • Telomeres are the ends of the eukaryotic chromosomes and consist of a tandem repetitive DNA sequence and shelterin protein complex. The function of telomere is to protect chromosome. Telomere length in somatic cells tends to decrease with organismal age due to the end replication problem. However, several factors at the genetic, epigenetic and environmental level affect telomere length. In this study, we estimated heritability of telomere length and investigated inheritance of telomeres in a chicken. Telomere length of lymphocytes was analyzed by semi-quantitative polymerase chain reaction using telomere primer and quantitative fluorescence in situ hybridization using telomeric DNA probe. In results, heritability of telomere length was estimated 0.9 at birth by offspring-parent regression analysis and was estimated 0.03 and 0.04 at 10 and 30 weeks old, respectively, by parental variance analysis. There was a significant positive correlation in telomere length between father and their offspring (r=0.348), and mother and their offspring (r=0.380). In inheritance patterns of telomere length, the influence of paternal and maternal effect on their offspring was similar. The influence of inherited telomeres on male and female progeny was also roughly alike. These results implicated that imprinting of parental telomere length was regulated by autosomal genes, not sex linked genes. In addition, telomere length of offspring at birth did not differ along with their maternal age. Thus, maternal age does not affects telomere length in their offspring at birth owing to cellular reprogramming at early embryonic stage.

Diallel Analysis and Least Square Estimators of Genetic Parameters

  • Shin, Han-Poong
    • Journal of the Korean Statistical Society
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    • v.4 no.2
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    • pp.139-151
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    • 1975
  • Individual effect of genes controlling quantitative traits can not ordinarily be distinguised from one another. Consequently, it is not possible to determine the mode of inheritance for single genes. By studying their combined effectsin segregating generations, however, one can gain some insight into their behavior and can make statistical inferences about their average gene action. The investigation reported herein was to extend genetic variance components and variance and covariance analyses, special attention was given to the genetic statistics from which least square estimators of genetic parameters are obtained.

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Recent Advances in Sheep Genome Mapping

  • Crawford, A.M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.12 no.7
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    • pp.1129-1134
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    • 1999
  • The rapid development of the sheep genetic linkage map over the last five years has given us the ability to follow the inheritance of chromosomal regions. Initially this powerful resource was used to find markers linked to monogenic traits but there is now increasing interest in using the genetic linkage map to define the complex of genes that control multigenic production traits. Of particular interest are those production traits that are difficult to measure and select for using classical quantitative genetic approaches. These include resistance to disease where a disease challenge (necessary for selection) poses too much risk to valuable stud animals and meat and carcass qualities which can be measured only after the animal has been slaughtered. The goal for the new millennium will be to fully characterise the genetic basis of multigenic production traits. The genetic linkage map is a vital tool required to achieve this.