• Biomolecules & Therapeutics
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• v.25 no.6
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• pp.559-568
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• 2017

Metabolomics has been used as a powerful tool for the analysis and quality assessment of the natural product (NP)-derived medicines. It is increasingly being used in the quality control and standardization of NP-derived medicines because they are composed of hundreds of natural compounds. The most common techniques that are used in metabolomics consist of NMR, GC-MS, and LC-MS in combination with multivariate statistical analyses including principal components analysis (PCA) and partial least squares-discriminant analysis (PLS-DA). Currently, the quality control of the NP-derived medicines is usually conducted using HPLC and is specified by one or two indicators. To create a superior quality control framework and avoid adulterated drugs, it is necessary to be able to determine and establish standards based on multiple ingredients using metabolic profiling and fingerprinting. Therefore, the application of various analytical tools in the quality control of NP-derived medicines forms the major part of this review. $Veregen^{(R)}$ (Medigene AG, Planegg/Martinsried, Germany), which is the first botanical prescription drug approved by US Food and Drug Administration, is reviewed as an example that will hopefully provide future directions and perspectives on metabolomics technologies available for the quality control of NP-derived medicines.

• Journal of Internet Computing and Services
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• v.14 no.3
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• pp.1-13
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• 2013

The recent emergence of diverse platform-based media devices such as smart phones and iPads has aroused interest of consumers all across the world. This interest has led to digitalization of paper books and a steep growth in the digital publishing industry at home and abroad. However, advent of various devices and content has caused the issue of compatibility and produced needs and demand for standardization to exchange and share content related to digital publication. Through collection of opinions of 16 stakeholders from the industrial, academic, research, and public sectors, this study aims to examine predictable future changes about content and its distribution, devices, standardization, technical protective measures, and obstacles in future digital publishing and eventually to draw out areas and elements for future standards development.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 1999.11a
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• pp.43-47
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• 1999

Recently, standardization organizations including ITU, ATM Forum, etc. have much interested in the interoperability issues between telecommunications products or services. Because interoperability issues are directly related to the improvement of qualities of telecommunications standards or services. Thus, this paper analyzes the trends of interoperability testing polices for quality improvement of telecommunications standards in major standardization organizations, for example ITU-T, ATM Forum, DAVIC, BC-lT 226(Europe), HATS Conference(Japan), including Korea. In addition this paper suggests the desirable national interoperability testing policies and directions for quality improvement of telecommunications standards or services.

• Journal of Mushroom
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• v.12 no.1
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• pp.67-72
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• 2014

This study was carried out to provide standardization for mushroom production of high quality at farmhouse. The standardization does much to improve merchantable quality, distribution efficiency and fair dealings by shipping of the standard agricultural products. Therefore, modification of these standards is required to fit farmhouse situations. The standardization for production of Pleurotus eryngii of high quality follows like this. A grades were above 90 g at average weight, more 50 mm at stipe thick, 1.6~1.7 at stipe length/stipe thick rate and 1.1~1.2 at pileus diameter/stipe thick ratio. B grades were more 45 g at average weight, above 40 mm at stipe thick, 1.8~1.9 at stipe length/stipe thick ratio and 1.2~1.4 at pileus diameter/stipe thick ratio.

• Journal of Gastric Cancer
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• v.5 no.2
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• pp.79-88
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• 2005

Quality assurance may be defined as the complete set of systemic actions that is required to achieve a better treatment result by standardizing treatment and by using various audit programs. In general, application of a quality assurance program in surgery is considered to be more difficult than it is in chemotherapy or radiotherapy. However, recently, the importance of quality assurance in the surgical field has been emphasized in clinical trials comparing different surgical procedures and evaluating the role of postoperative adjuvant therapy. In the case of gastric cancer surgery, excellent quality assurance programs have rarely been applied in most large prospective clinical trials. Although the quality assurance in Dutch trial was conducted very systemically and strictly, the situation is quite different from ours. On the other hand, several quality assurance programs in Japanese trials comparing D2 and D2 plus para-arotic lymph node dissection seem to be applicable to Korean clinical trials. Several factors, including selection of appropriate surgeons based on personal experience and annual number of operations, standardization of surgical procedures by education and consensus, development of a unified database program, application of standardized perioperative management, and standardization of pathologic examination, are required to guarantee a successful multi-institutional prospective clinical trial. In contrast, one needs to realize that protocols that are too strict and sophisticated can make the enrollment of patients and surgeons more difficult and can promote protocol violation during the clinical trials. (J Korean Gastric Cancer Assoc 2005;5:79-88)

• 전자공학회논문지 IE
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• v.45 no.1
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• pp.58-64
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• 2008

This Paper provides perceptual metrics for video quality based on properties of human visual system, and audio quality based on human audition. All metrics work without reference signals, allowing non-intrusive, in-service measurements. A simple and easy-to-learn user interface displays the metrics and saves them in popular file formats like CSV. In this paper, proposed method was able to various and corrective measurement for the multimedia service video quality. As that it was able to application to set up service guide line and the methode of measurement and system for the set up standardization of the high quality video service.

• Journal of Physiology & Pathology in Korean Medicine
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• v.30 no.6
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• pp.397-401
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• 2016

The quality control is a fundamental procedure for the standardization of herbal medicine to guarantee the consistency of efficacy and safety. For a long time, the quality analysis of herbal medicine has been largely dependent on the routine sensory evaluation, such as taste, smell, color, and shape. However, with the recent development of analytical instruments, various scientific approaches have been introduced in this field. On the basis of the theory that the biological activities of herbal medicine are mainly contributed by its chemical compositions, several types of chemical markers have been suggested for the quality evaluation. In addition to the analytical methods for the specific marker compound(s), including analytical marker and active marker, recently, chemical fingerprinting, a method comparing the chromatographic pattern of the whole chemical components, has been developed and widely accepted as a reliable approach for the quality control of herbal medicine. Moreover, in order to exactly understand the relationship between complex compounds and their holistic biological activities in herbal medicine, unique strategies, such as "BECCs (bioactive equivalent combinatorial components)" and "PhytomicsQC" have been established. In this article, we give an overview of the several categories of chemical markers and the recent research trends for the quality evaluation of herbal medicine.

• Journal of Korean Society for Quality Management
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• v.23 no.4
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• pp.180-189
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• 1995

Today, as globalization continues and international trading blocks are formed, world markets are intensely competitive and abound in product variety, volume, complexity and environmental management. Specifically, green consumer's needs and expectations are changing and diversifying, resulting in a changed global environment for industry. Due to these changes, domestic companies are striving to achieve the Environmental Management System (ISO 14000) certification. This is considered a basis step in meeting the guiding principle and practice of ISO/TC 207/SC 3 resolution. In this paper, we will present three type(I, II, III) of Environmental Labelling programs to build a model for environmental management system by analysing practitioner and stakeholder. After companies establish an ISO 9000 quality system these companies should focus on improve toward their own Environmental Labelling program and continue to build ISO 14000.

• Journal of Korean Society for Quality Management
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• v.46 no.3
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• pp.379-396
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• 2018

Purpose: The purpose of this study was to propose a standard form of noise filter drawing, which is widely used in the field of weapon systems, to define the essential specification which is not standardized at the existing drawings and to employ the reference for manufacturing and qualification test. Methods: To do that, it identifies the improvements to analyze 19 noise filter drawings, studies the principle of noise filtering to find the essential part of the spec. and reviews the MIL-STD-220C and KS IEC 60939, which is the widely used as a formal spec. pertaining to the noise filter. Throughout the study, a standard form is developed to standardize the attenuation characteristics and find eight crucial metrics to specify the noise filter. Results: The results of this study are as follows; The standardized drawings can be used as the qualification test of the item and the manufacturing and engineering documents to make the noise filter, which are also applicable to the reference document to review KDS(Korea Defense Standard) drawings.

• Journal of the Korean Society of Industry Convergence
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• v.23 no.2_2
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• pp.225-232
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• 2020

In this paper, we introduce the results of investigating and overhauling bearing drawings in the defense field, and propose an effective bearing drawing management system. We identify the features and performance items that must be regulated in the bearing drawing. After reviewing the validity of the bearing drawings, we classify the incorrect drawings by factor. To achieve greater effect, standardized formats are needed to incorporate into the drawing in the early stage. We propose the introduction of a bearing drawing management system so that the developing bearing technology can be applied quickly to the defense sector. As other elementary parts of the machine have similar problems, we think this study will help develop improvement plans.