• 문화기술의 융합
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• 제5권1호
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• pp.451-456
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• 2019

우리사회는 우리나라 학생들의 학업성적과 삶의 만족도가 반비례 한다는 보고가 나와 충격을 받고 있다. 경제협력개발기구(OECD)가 발표한 국제학업성취도평가(PISA) '2015 학생 삶의 질 만족도 보고서'에 의하면 한국 학생들의 학력수준은 OECD 국가 가운데 최상위층이지만 '삶의 만족도'는 비 OECD국가를 포함한 OECD국가 48개국 중 47위로 최하위권으로 나타났다.[1] 이것은 집단적인 성적위주 평가방식의 일방적인 교육이 그 요인이라고 보고 블록 체인 기술을 활용한 개인맞춤형 통합 모델을 연구하고자 한다. 보안성, 투명성, 분산성이 특징인 블록체인 기술을 활용하여 공급자 일방의 교육 및 일방적인 개인성적 공개위주 시스템에서 선택교육 및 개인승인을 통한 개인맞춤형 교육 및 평가시스템 모델을 연구하였다. 이 연구를 통하여 교육의 본질을 고려하면서 개인별 맞춤교육 및 평가관리시스템이 학생 삶의 질 개선에 기여한 의의를 가지고자 한다.

• 산업진흥연구
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• 제8권4호
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• pp.229-239
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• 2023

이 연구는 집중산만 전략을 활용한 건강염려증의 해소 방안을 모색하는 문헌연구이다. 건강염려증은 우리말로 건강기우증, 건강불안, 질병공포, 질병불안장애, 건강염려성 신경증, 건강염려성 성격장애, 신체 증상장애 등의 용어로 불리워지나 이 연구에서는 건강염려증으로 명명한다. 이는 기본적으로 염려, 두려움, 불안 더 나아가 공포를 야기하여 가정, 직장 및 사회에서 삶의 질을 저하하게 만드는 요인이다. 건강염려증은 주로 중년기 성인들이 겪는 심리적 문제로서 자기자신에게 집중, 몰두하다가 이에 노출된다. 이 증상은 건강에 대한 지나친 염려로 인해 빈번한 건강검진 등 병원을 전전하면서 상당한 사회적 비용이 소비되고, 개인의 삶의 질이 저하되어 상담심리, 심리상담 분야에서는 이 문제를 해결해주고, 심리적 평안을 회복하도록 해야 하는 과제를 안고 있다. 따라서 이 연구는 건강염려증을 해소할 수 있는 방안으로 인지 전략 가운데 집중산만 전략을 활용하여 그 증상 해소를 모색해보려는 시도라 할 수 있다. 집중산만 전략은 일종의 인지적 '회피 전략'이라 할 수 있다. 자신의 건강에 대하여 지나치게 집중하는 인식, 주의를 회피, 다른 방향으로 '분산'시키거나 '산만'하게 하는 것으로 건강염려를 약화시키는 것이다.

• Bulletin of the Korean Chemical Society
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• 제28권6호
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• pp.947-952
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• 2007

Mycobacterium tuberculosis is a pathogen responsible for 2-3 million deaths every year worldwide. The emergence of drug-resistant and multidrug-resistant tuberculosis has increased the need to identify new antituberculosis targets. Acetohydroxy acid synthase, (AHAS, EC 2.2.1.6), an enzyme involved in branched-chain amino acid synthesis, has recently been identified as a potential anti-tuberculosis target. To assist in the search for new inhibitors and “receptor-based” design of effective inhibitors of tubercular AHAS (TbAHAS), we constructed four different structural models of TbAHAS and used one of the models as a target for virtual screening of potential inhibitors. The quality of each model was assessed stereochemically by PROCHECK and found to be reliable. Up to 89% of the amino acid residues in the structural models were located in the most favored regions of the Ramachandran plot, which indicates that the conformation of each residue in the models is good. In the models, residues at the herbicide-binding site were highly conserved across 39 AHAS sequences. The binding mode of TbAHAS with a sulfonylurea herbicide was characterized by 32 hydrophobic interactions, the majority of which were contributed by residue Trp516. The model based on the highest resolution X-ray structure of yeast AHAS was used as the target for virtual screening of a chemical database containing 8300 molecules with a heterocyclic ring. We developed a short list of molecules that were predicted to bind with high scores to TbAHAS in a conformation similar to that of sulfonylurea derivatives. Five sulfonylurea herbicides that were calculated to efficiently bind TbAHAS were experimentally verified and found to inhibit enzyme activity at micromolar concentrations. The data suggest that this time-saving and costeffective computational approach can be used to discover new TbAHAS inhibitors. The list of chemicals studied in this work is supplied to facilitate independent experimental verification of the computational approach.

• The Korean Journal of Pain
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• 제36권1호
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• pp.84-97
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• 2023

Background: The concept of high-impact chronic pain (HICP) has been proposed for patients with chronic pain who have significant limitations in work, social life, and personal care. Recognition of HICP and being able to distinguish patients with HICP from other chronic pain patients who do not have life interference allows the necessary measures to be taken in order to restore the physical and emotional functioning of the affected persons. The aim was to reveal the risk factors and predictors associated with HICP. Methods: Patients with chronic pain without life interference (grade 1 and 2) and patients with HICP were compared. Significant data were evaluated with regression analysis to reveal the associated risk factors. Receiving operating characteristic (ROC) analysis was used to evaluate predictors and present cutoff scores. Results: One thousand and six patients completed the study. From pain related cognitive processes, fear of pain (odds ratio [OR], 0.92; 95% confidence interval [CI], 0.87-0.98; P = 0.007) and helplessness (OR, 1.06; 95% CI, 1.01-1.12; P = 0.018) were found to be risk factors associated with HICP. Predictors of HICP were evaluated by ROC analysis. The highest discrimination value was found for pain intensity (cut-off score > 6.5; 83.8% sensitive; 68.7% specific; area under the curve = 0.823; P < 0.001). Conclusions: This is the first study in our geography to evaluate HICP with measurement tools that evaluate all dimensions of pain. Moreover, it is the first study in the literature to evaluate predictors and cut-off scores using ROC analysis for HICP.

• 디지털융복합연구
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• 제12권12호
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• pp.561-570
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• 2014

본 연구는 장애인들의 일상생활 경험에서 어려움을 알아보고자 하였다. 이를 위해 서울지역 재가 장애인 8명을 심층면접 실시하여 합의적 질적(CQR) 방법으로 분석하였다. 연구 결과는 3개의 범주에서 14개 영역 및 그에 따른 48개의 내용에 따라 빈도분석을 하였다. 장애인들의 일상생활에서 심리 정서적 경험의 어려움은 자신감 결여, 건강문제 염려, 결혼(재혼) 및 이성문제, 가족관계 어려움, 외로움, 노후문제 염려로 나타났다. 사회 경제적 경험의 어려움은 관계의 어려움, 생계문제, 출산 양육문제, 직장생활 어려움, 외출 시 번거로움으로 나타났다. 이러한 경험들을 대처하는 과정으로는 종교기관 모임, 지역사회체계 이용, 주변사람들의 도움을 이용하였다. 본 연구 결과에 의하여 장애인들이 일상생활에서 어려움을 잘 극복할 수 있도록 실질적인 도움이 되는 사회복지서비스와 지역사회체계를 통하여 지속적인 지원이 필요함을 제언하였다.

• Animal Bioscience
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• 제35권10호
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• pp.1479-1488
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• 2022

Objective: This work was to determine coat inheritance and evaluate production performance for crossbred pigs from Berkshire×Chenghua (BC) compared with Chinese indigenous Chenghua (CH) pigs. Methods: The coat color phenotypes were recorded for more than 16,000 pigs, and the genotypes of melanocortin 1 receptor (MCIR) gene were identified by sequencing. The reproductive performance of 927 crossbred BC F4 gilts and 320 purebred CH gilts was recorded. Sixty pigs of each breed were randomly selected at approximately 60 days of age to determine growth performance during fattening period, which lasted for 150 days for BC pigs and 240 days for CH pigs. At the end of the fattening period, 30 pigs of each breed were slaughtered to determine carcass composition and meat quality. Results: The coat color of BC pigs exhibits a "dominant black" hereditary pattern, and all piglets derived from boars or sows genotyped E^D1 E^D1 homozygous for MC1R gene showed a uniform black coat phenotype. The BC F4 gilts displayed a good reproductive performance, showing a higher litter and tear size and were heavier at farrowing litter and at weaning litter than the CH gilts, but they reached puberty later than the CH gilts. BC F4 pigs exhibited improved growth and carcass characteristics with a higher average daily live weight gain, lower feed-to-gain ratio, and higher carcass lean meat rate than CH pigs. Like CH pigs, BC F4 pigs produced superior meat-quality characteristics, showing ideal pH and meat-color values, high intramuscular fat content and water-holding capacity, and acceptable muscle-fiber parameters. C18:1, C16:0, C18:0, and C18:2 were the main fatty acids in M. longissimus lumborum in the two breeds, and a remarkably high polyunsaturated/saturated fatty acid ratio of ~0.39 was observed in the BC F4 pigs. Conclusion: The BC F4 pigs exhibit a uniform black coat pattern and acceptable total production performance.

• 한국산업정보학회논문지
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• 제4권3호
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• pp.1-7
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• 1999

소프트웨어 프로젝트 관리과정의 활동에서 프로젝트 관리자의 중요한 임무는 소프트웨어의 크기와 인적 노력 등을 예측하는 것이다. 최근 소프트웨어 개발에 주로 사용되는 제 4세대 언어(4GL)와 데이터베이스 환경에서 개발되는 프로젝트에 대한 크기를 예측하는 모델은 불행하게도 연구가 미비한 실정이다. 본 논문에서는 4GL로 개발되는 프로젝트 개발 초기 단계에서 수집한 메트릭스를 이용하여 소프트웨어 크기를 예측하는 추정 모델을 제안 한다. 제안된 방법은 상대오차(MRE)를 최소화시키는 방법으로 개발 초기과정에서 얻어지는 측도들의 이상치에 덜 민감한 특성을 가지고 있다. 본 논문에서 제안된 모델에 대하여 적합도와 예측력의 성능을 테스트하기 위하여 데이터 ？을 I,II 2개로 나누어 실험하였다. 실험결과, 추정된 모델의 적합도와 예측력은 제안된 MRE 추정방법이 데이터 셀 I,II 모두에서 전통적인 방법 LS, RLS보다 우수하게 나타났다.

• 한국산업정보학회:학술대회논문집
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• 한국산업정보학회 1999년도 춘계학술대회 발표논문집
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• pp.97-105
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• 1999

소프트웨어 프로젝트 관리과정의 활동에서 프로젝트 관리자의 중요한 임무는 소프트웨어의 크기와 인적 노력 등을 추정하는 것이다. 최근 소프트웨어 개발에 주로 사용되는 제 4세대 언어(4GL)와 데이터베이스 환경에서 개발되는 응용시스템에 대한 크기를 예측하는 모델은 불행하게도 연구가 미비한 실정이다. 본 논문에서는 4GL로 개발되는 프로젝트 개발 초기 단계에서 수집한 메트릭스를 이용하여 소프트웨어 크기를 예측하는 추정 모델을 제안 한다. 제안된 방법은 상대오차(MRE)를 최소화시키는 방법으로 개발 초기과정에서 얻어지는 측도들의 이상치에 덜 민감한 특성을 가지고 있다. 본 논문에서 제안된 모델에 대하여 적합도와 예측력의 성능을 테스트하기 위하여 데이터 셀을 I과 II 2개로 나누어 실험하였다. 실험결과, 추정된 모델의 적합도와 예측력은 데이터 셀 I과 II 모두에서 제안된 MRE 추정방법이 전통적인 방법 LS, RLS보다 우수하게 나타났다.

• KIEAE Journal
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• 제7권5호
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• pp.93-98
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• 2007

Effort has been performed for latest 20 years to improve resident's comfort and indoor environment in building. And interest and effort to improve indoor air environment among various indoor environment elements have continuously increased since 1990s, because it is examined scientifically that various contaminants generated indoor affect human body. Specially, indoor air contaminants generated from apartments are those exhausted from resident's indoor environment, closing materials and household. Indoor air environment in buildings is different according to pollution degree, existence availability of pollution source, ventilation amount, and meteorology. It is known that other contaminants more than about 900 kinds generate according to a kind of work or action in a room. Specially, nowadays buildings are well insulated and confidentiality-centered for environment protection and economical side. So indoor air contaminants are generated from indoor air pollution sauces of unprepared ventilation, human body carbon dioxide emissions, and various building materials. when these are accumulated in long term human body, it is harmful to resident's health, but awareness for this is very insufficient. Because bedroom is space that people inhabit for a long time by unconscious state and indoor environment occupies important part for resident's health and quality of life at sleep, the actual condition of air quality is investigated, improvement countermeasure is considered, and ventilation amount is analyzed. In this study, putting case that the most longest stayed time is sleeping time when people inhabit in the apartment, the air quality according to volume of bedroom space at sleep was measured and analyzed, and the data acquired will be the basis for improvement on this.

• International Journal of Computer Science & Network Security
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• 제22권7호
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• pp.35-42
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• 2022

The article identifies the problem of monitoring the quality of higher education in three main areas, which are comparative pedagogical systems of education. The first direction is determined by dissertation works, the second - monographs and textbooks, and the third reveals scientific periodicals. According to its internal structure, monitoring the quality of education combines important management components identified in the article (analysis, evaluation and forecasting of processes in education; a set of methods for tracking processes in education; collecting and processing information to prepare recommendations for research processes and make necessary adjustments). Depending on the objectives, three areas of monitoring are identified: informational (involves the accumulation, structuring and dissemination of information), basic (aimed at identifying new problems and threats before they are realized at the management level), problematic (clarification of patterns, processes, hazards, those problems that are known and significant from the point of view of management). According to its internal structure, monitoring the quality of education combines the following important management components: analysis, evaluation and forecasting of processes in education; a set of techniques for tracking processes in education; collection and processing of information in order to prepare recommendations for the development of the studied processes and make the necessary adjustments. One of the priorities of the higher education modernization program during the COVID-19 pandemic is distance learning, which is possible due to the existence of information and educational technologies and communication systems, especially for effective education and its monitoring in higher education. The conditions under which the effectiveness of pedagogical support of monitoring activities in the process of distance learning is achieved are highlighted. According to the results of the survey, the problems faced by higher education seekers are revealed. A survey of students was conducted, which had a certain level of subjectivity in personal assessments, but the sample was quite representative.