• Radiation Oncology Journal
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• v.29 no.2
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• pp.63-70
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• 2011

Purpose: To evaluate the extent of pain response and objective response to palliative radiotherapy (RT) for bone metastases from hepatocellular carcinoma according to RT dose. Materials and Methods: From January 2007 to June 2010, palliative RT was conducted for 103 patients (223 sites) with bone metastases from hepatocellular carcinoma. Treatment sites were divided into the high RT dose and low RT dose groups by biologically effective dose (BED) of 39 $Gy_{10}$. Pain responses were evaluated using the numeric rating scale. Pain scores before and after RT were compared and categorized into 'Decreased', 'No change' and 'Increased'. Radiological objective responses were categorized into complete response, partial response, stable disease and progression using modified RECIST (Response Evaluation Criteria In Solid Tumors) criteria; the factors predicting patients' survival were analyzed. Results: The median follow-up period was 6 months (range, 0 to 46 months), and the radiologic responses existed in 67 RT sites (66.3%) and 44 sites (89.8%) in the high and low RT dose group, respectively. A dose-response relationship was found in relation to RT dose (p=0.02). Pain responses were 75% and 65% in the high and low RT dose groups, respectively. However, no statistical difference in pain response was found between the two groups (p=0.24). There were no differences in the toxicity profiles between the high and low RT dose groups. Median survival from the time of bone metastases diagnosis was 11 months (range, 0 to 46 months). The Child-Pugh classification at the time of palliative RT was the only significant predictive factor for patient survival after RT. Median survival time was 14 months under Child-Pugh A and 2 months under Child-Pugh B and C. Conclusion: The rate of radiologic objective response was higher in the high RT dose group. Palliative AT with a high dose would provide an improvement in patient quality of life through enhanced tumor response, especially in patients with proper liver function.

• Journal of Korean Society of Environmental Engineers
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• v.38 no.1
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• pp.14-24
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• 2016

Information on the lists of pollutants from industrial wastewater discharge are essential not only to specify the key pollutants to be managed in permission process but to design the treatment facilities by the dischargers. In this study, wastewater quality analysis was conducted for three industrial categories including the specified hazardous water pollutants. The general description of the wastewater occurrence, major sources, treatment facilities are also investigated to obtain integrated database on the pollutant inventories for the industrial categories. In addition Based on the analysis of raw wastewater and final effluent, the detected pollutant items are confirmed by analyzing their presence in the raw or supplement materials, the potential of formation as byproducts, and the possibility of inclusion as impurities. The three industrial categories include petrochemical basic compounds, basic organic compounds, and thermal power generation. The water pollutants emitted from petrochemical basic compound manufacturing facilities are 31 items including 16 specified hazardous water pollutants. Basic organic compound manufacturing facilities discharge 30 kinds of pollutants including 14 specified hazardous water pollutants. Thermal power generation facilities emit 20 pollutants, 8 specified hazardous water pollutants among them. These substances were decided as emission inventories of water pollutants finally through the probability evaluation. The compounds detected for each categories are screened through investigation on the possible causes of their occurrence and confirmed as the final water pollutant inventories.

• Journal of Food Hygiene and Safety
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• v.14 no.4
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• pp.372-379
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• 1999

A bacteriological study of sea water and oyster in Tongyeong coastal area was conducted to evaluate sanitary conditions of the bay and compliance of waters with the recommended bacteriological criteria fur the designated area of shellfish cultivation. The Samples were collected at 5 zone, 34 sampling stations(Fig. 1) established once a month from September 1997 to August 1998. During the study period, temperature ranged from 6.9 to 23.6$^{\circ}C$, transparency ranged from 2.6 to 6.2 m, chemical oxygen demand ranged from 1.35 to 1.82 mg/ι, dissolved oxy-gen ranged from 5.0 to 9.9 mg/ι, dissolved nitrogen ranged from 1.60 to 8.17 $\mu\textrm{g}$-at/ι, phosphate ranged from 0.14 to 1.21 $\mu\textrm{g}$-at/ι, Chlorophyll-a ranged from 2.03 to 69.9 mg/㎥, respectively. The coliform group and fecal coliform MPN's of sea water were ranged from <3.0~1,600 and <3.0~540, respectively. The coliform group and fecal coliform MPN's of oysters were ranged from <18~16,000 and <18~2,200, respectively. The viable cell counts in oyster ranged from $1.5\times$10$^2$to 8.2$\times$10$^3$. The coliform stoup, fecal coliform, classification of coliform group with IMViC reactions and pathogenic vibrios were analyzed. 437 strains that were obtained from Tongyeoung coastal area seawater samples represented E. coli group 47.5%, C. freundii group 14.8%, K. aerogenes 10.9%, unknown 26.8%, respectively. During the study period, infectious bacteria such as Vibrio ohoEerae, Salmonella sp. and Shigella sp. were not detected from the samples, but detection ratios of Vibrio parahaemolyticus and Vibrio vulnificus were 12~21% in summer months.

• Journal of Korean Society of Environmental Engineers
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• v.22 no.7
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• pp.1331-1343
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• 2000

Through the integration of USLE and GIS, the methodology to estimate the soil loss was developed, and applicated to the Sacheon river in Gangrung. Using GIS, spatial analysis such as watershed boundary determination, flow routing. slope steepness calculation was done. Spatial information from the GIS application was given for each grid. With soil and land use map, information about soil classification and land use was given for each grid too. Based upon these data, thematic maps about the factors of USLE were made. We estimated the soil loss by overlaying the thematic maps. In this manner, we can assess the degree of soil loss for each grid using GIS. Annual average soil loss of Sacheon river watershed is 1.36 ton/ha/yr. Soil loss in forest, dry field, and paddy field is 0.15 ton/ha/yr, 27.04 ton/ha/yr, 0.78 ton/ha/yr respectively. The area of dry field, which is 4% of total area, is $2.4km^2$. But total soil loss of dry field is 6561 ton/yr, and it occupies 84.9 % of total soil loss eroded in Sacheon river watershed. Comparing with the 11.2 ton/ha/yr of an average soil loss tolerance for cropland, provision for the soil loss in dry field is necessary. Run-off and water quality of Sacheon river were measured two times in flood season: from July 24, 1998 to July 28 and from September 29 to October 1. As the run-off of the river increased, SS, TN, TP concentrations and pollutant loadings increased. SS, TN, TP loads of Sacheon river discharged during the 2 heavy rains were 21%, 39%, and 19% of the total pollutant loadings generated in the Sacheon river watershed for one year. We can see that much pollutants are discharged in short period of flood season.

• Journal of Korean Home Economics Education Association
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• v.16 no.3
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• pp.81-98
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• 2004

This study is to conduct the basic study for the achievement and assessment standards for the subject of 'Human Development' and 'Food and Nutrition', which are the curricula of Vocational Home Economics High Schools. These two subjects were newly adopted in the Vocational study Section of the 2005 College Entrance Examinations. In other words, this study is to provide the basic data for implementing the quality education based on the proper assessment of the curricula. For this purpose. this study analyzed the character & objective of 'Human Development' and 'Food and Nutrition'. Secondly. through the theoretical review for the concept & necessity of absolute evaluation standards. this study ensures the concept of achievement and assessment standards. and also designs the developing measures (including procedures). The achievement standards were developed by the following 5 step procedures. (1) Analyzing the objectives & contents of curricula. (2) Designating the development field of achievement standards (3) Developing the achievement standards. (4) The assessment of achievement standards. (5) Confirming the achievement standards. The assessment standards were developed by the following 5 step procedures. (1) Analyzing the achievement standards, (2) Designating the assessment field (3) Developing the assessment standards (4) Evaluating the assessment standards (5) Confirming the assessment standards Thirdly, this study suggested the exemplary achievement standards and assessment standards for the subject of Human Development, Food and Nutrition. Future study needs some critical review for the method of developing achievement and assessment standards for the subject of Human Development, Food and Nutrition. For example. the properness of 'Contents Element' which was designated as the developing field in the achievement standards, the discussion on validity of Contents Element abstract. the base of evaluating classification in terms of low, middle and high level, and other things should be considered through critical discussion. Especially the follow-up study should include the development of various evaluating methods to enable the clear communication for the achievement and assessment standards based on abstract concept and theory, thereby it could enable the actual interpretation and practical use.

• Korean Journal of Soil Science and Fertilizer
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• v.37 no.4
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• pp.199-206
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• 2004

Factors of universal soil loss equation, USLE, and its revised version, RUSLE for Korean soils were reevaluated to estimate the national scale of soil loss based on digital soil maps. Rainfall erosivity factor, R, of 158 locations of cities and counties were spacially interpolated by the inverse distance weight method. Soil erodibility factor, K, of 1321 soil phases of 390 soil series were calculated using the data of soil survey and agri-environmental quality monitoring. Topographic factor, LS, was estimated using soil map of 1:25,000 scale with soil phase and land use type. Cover management factor, C, of major crops and support practice factor, P, were summarized by analyzing the data of lysimeter and field experiments for 27 years (1975-2001) in the National Institute of Agricultural Science and Technology. R factor varied between 2322 and 6408 MJ mm $ha^{-1}$ $yr^{-1}$ $hr^{-1}$ and the average value was 4276 MJ mm $ha^{-1}$ $yr^{-1}$ $hr^{-1}$. The average K value was evaluated as 0.027 MT hr $MJ^{-1}$ $mm^{-1}$. The highest K factor was found in paddy rice fields, 0.034 MT hr $MJ^{-1}$ $mm^{-1}$, and K factors in upland fields, grassland, and forest were 0.026, 0.019, and 0.020 MT hr $MJ^{-1}$ $mm^{-1}$, respectively. C factors of upland crops ranged from 0.06 to 0.45 and that of grassland was 0.003. P factor varied between 0.01 and 0.85.

• Environmental and Resource Economics Review
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• v.14 no.1
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• pp.167-199
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• 2005

The following policy implications can be drawn from this study: 1) The Air Pollution Emission Amount Report published by the Ministry of Environment since 1991 classifies industries into 4 sectors, i. e., heating, manufacturing, transportation and power generation. Currently, the usability of report is very low and extra efforts should be given to refine the current statistics and to improve the industrial classification. 2) Big pollution industries are as follows - s7, s17 and s20. The current air pollution control policy for these sectors compared to other sectors are found to be inefficient. This finding should be noted in the implementation of future air pollution policy. 3) s10 and s17 are found to be a big polluting industrial sector and its pollution reduction effect is also significant. 4) The effect of emission coefficient (${\Delta}f$) has the biggest impact on the reduction of emission amount change and the effect of economic growth coefficient (${\Delta}y$) has the biggest impact on the increase of emission volume. The effect of production technology factor (${\Delta}D$) and the effect of the change of the final demand structure (${\Delta}u$) are insignificant in terms of the change of emission volume. 5) Further studies on emission estimation techniques on each industry sector and the economic analysis are required to promote effective enforcement of the total volume control system of air pollutants, the differential management of pollution causing industrial sectors and the integration of environment and economy. 6) Korea's economic growth in 1990 is not pollution-driven in terms of the Barry Commoner's hypothesis, even though the overall industrial structure and the demand structure are not environmentally friendly. It indicates that environmental policies for the improvement of air quality depend mainly on the government initiatives and systematic national level consideration of industrial structures and the development of green technologies are not fully incorporated.

• The Korean Society of Law and Medicine
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• v.17 no.2
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• pp.85-124
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• 2016

The Human gene testing act (GenDG) in Germany starts from the characteristic features of gene testing, i.e. dualisting structure consisted of anlaysis on the one side and the interpretation on the other side. The linguistic distincion of 'testing', 'anlaysis' and 'judgment' in the act is a fine example. Another important basis of the regulation is the ideological purpose of the law, that is information autonomy. The normative texts as such and the founding principle are the basis of the classification of testing types. Especially in the case of gene testing for medical purpose is classified into testing for diagnostic purpose and predictive purpose. However, those two types are not always clearly differentiated because the predictive value of testing is common in both types. In the legal regulation of gene testing it is therefore important to manage the uncertainty and subjectivity which are inherent in the gene-analysis and the judgment. In GenDG the system ensuring the quality of analysis is set up and GEKO(Commity for gene tisting) based on the section 23 of GenDG concretes the criterium of validity through guidelines. It is also very important in the case of gene testing for medical purpose to set up the system for ensurement of procedural rationality of the interpretation. The interpretation of the results of analysis has a wide spectrum because of the consistent development of technology on the one side and different understandings of different subjects who performs gene testings. Therefore the process should include the communication process for patients in oder that he or she could understand the meaning of gene testing and make plans of life. In GenDG the process of genetic counselling and GEKO concretes the regulation very precisely. The regulation as such in GenDG seems to be very suggestive to Korean legal polic concerning the gene testing.

• Journal of Food Hygiene and Safety
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• v.33 no.5
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• pp.404-411
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• 2018

To evaluate bacteriological and toxicological safety hygienic indicator bacterium and paralytic and diarrhetic shellfish toxins in the shellfish produced in Hansan Geojeman 2013-2017 were investigated. Fecal coliforms were < 18~330 MPN/100 g in 404 oyster samples. But all samples tested, did not exceed 230 E. coli MPN/100 g. Geometric mean of E. coli for oyster samples collected during major shellfish production period was 24.3 MPN/100 g, considerde stable results. Bacteriological quality of oysters collected from Hansan Geojeman meets the standard value based on shellfish hygiene of the Food Sanitation Act of Korea and also meets Grade A, according to classification of shellfish harvesting areas of the European Union. For toxicological evaluation of Hansan Geojeman, 532 oyster samples and 268 mussel samples as an indicator, were analyzed. Paralytic shellfish toxins were detected in the range of 0.42~2.29 mg/kg in eight mussel samples, and exceeded criteria in three samples from early to late April 2013. Diarrhetic shellfish toxin was detected in three of 120 samples, but it was revealed to be under regulation value (0.16 mg Okadaic Acid equ./kg). As a result of toxicological evaluation, paralytic and diarrhetic shellfish toxins were not detected in oyster samples, but it was found that mussel as an indicator species, exceeded the threshold value of paralytic shellfish toxin. Accordingly, sanitary surveys were continuously requested for food safety management of shellfish.

• KIPS Transactions on Software and Data Engineering
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• v.9 no.10
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• pp.303-308
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• 2020

The ReLU(Rectified Linear Unit) function has been dominantly used as a standard activation function in most deep artificial neural network models since it was proposed. Later, Leaky ReLU, Swish, and Mish activation functions were presented to replace ReLU, which showed improved performance over existing ReLU function in image classification task. Therefore, we recognized the need to experiment with whether performance improvements could be achieved by replacing the RELU with other activation functions in the super resolution task. In this paper, the performance was compared by changing the activation functions in EDSR model, which showed stable performance in the super resolution task. As a result, in experiments conducted with changing the activation function of EDSR, when the resolution was converted to double, the existing activation function, ReLU, showed similar or higher performance than the other activation functions used in the experiment. When the resolution was converted to four times, Leaky ReLU and Swish function showed slightly improved performance over ReLU. PSNR and SSIM, which can quantitatively evaluate the quality of images, were able to identify average performance improvements of 0.06%, 0.05% when using Leaky ReLU, and average performance improvements of 0.06% and 0.03% when using Swish. When the resolution is converted to eight times, the Mish function shows a slight average performance improvement over the ReLU. Using Mish, PSNR and SSIM were able to identify an average of 0.06% and 0.02% performance improvement over the RELU. In conclusion, Leaky ReLU and Swish showed improved performance compared to ReLU for super resolution that converts resolution four times and Mish showed improved performance compared to ReLU for super resolution that converts resolution eight times. In future study, we should conduct comparative experiments to replace activation functions with Leaky ReLU, Swish and Mish to improve performance in other super resolution models.