• Title/Summary/Keyword: q-series

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3D-QSAR Analysis on the Fungicidal Activity with N-Phenylbenzenesulfonamide Analogues against Phytophthora blight (Phytophthora capsici) and Prediction of Higher Active Compounds (고추역병균(Phytophthora capsici)에 대한 N-Phenylbenzenesulfonamide 유도체들의 살균활성에 관한 3D-QSAR 분석과 고활성 화합물의 예측)

  • Soung, Min-Gyu;Kang, Kyu-Young;Cho, Yun-Gi;Sung, Nack-Do
    • Applied Biological Chemistry
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    • v.50 no.3
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    • pp.192-197
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    • 2007
  • 3D-QSARs on the fungicidal activity of N-phenylbenzenesulfonamide and N-phenyl-2-thienylsulfonamide analogues (1-37) against Phytophthora blight (Phytophthora capsici) were studied quantitatively using CoMFA and CoMSIA methods. The statistical results of the optimized CoMFA (2) model ($r^2_{cv.}(q^2)$ = 0.692 & $r^2_{ncv.}$= 0.965) show better predictability and fitness than CoMSIA (2) model ($r^2_{cv.}(q^2)$ = 0.796 & $r^2_{ncv.}$= 0.958). The fungicidal activities according to the information of the optimized CoMFA (2) model were dependent upon the steric and electrostatic fields of the molecules. Therefore, from the contribution contour maps of CoMFA (2) model, it is expected that 63% contribution was caused by the steric bulk of meta-substituent ($R_1$) on the S-phenyl ring. Also, the other contribution level of 32.9% was represented by the positive charged $R_4-group$ ($R_1$) on the N-phenyl ring and para-substituent ($R_1$) on the S-phenyl ring. A series of higher active compounds, $R_1$= 3-decyl substituent ($pred.pI_50$= 5.88) etc. were predicted based on the findings.

Respiration in the Adult of the Water Striders, Gerris paludum insuralis(Insecta, Hemiptera, Gerridae) (소금쟁이(G. paludum insuralis)성체의 흐름)

  • Park, Sang-Ock;Joo, Eun-Young
    • The Korean Journal of Zoology
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    • v.29 no.3
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    • pp.201-207
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    • 1986
  • The authors attempted to investigate the oxygen consumption rate of sexuals in the water-striders, Gerris paludum insuralis, at four temperature groups of 25, 30, 35 and $40^\\circ C$ in a series of studies on respiration of a heminetabolous insects. THe results are summarised as follows: (1) At $30^\\circ C$, the change of oxygen consumption rate according to the lapse of time was small in comparison with the other three temperature groups which shows a cyclic decreasing pattern. The rate during initial and final 5 minutes was much alike. Thereupon, the optimum temperature was regarded as $30^\\circ C$. (2) The oxygen consumption rate of male was higher than that of female. (3) The oxygen consumption rates at 25, 30, 35 and $40^\\circ C$ were 0.42, 0.49, 0.79 and 1.11 $\\mu$l/mg/h respectively. That is, the rate was increased as the temperature was increased. (4) The $Q_10$ of male showed a high value in the lower temperature interval ($25^\\circ C \\sim 35^\\circ C$), but the female showed a high value in the higher temperature interval ($30^\\circ C \\sim 40^\\circ C$). The mean $Q_10$ was 2.12. (5) The respiratory rate was decreased as the body weight was increased in the above fresh weight of 10mg and dry weight 5 mg. (6) The upper temperature threshold for respiration was $48.31^\\circ C$ and the lower temperature threshold was $17.68^\\circ C$. (7) The ceasing time of breathing at the other three temperature groups except $30^\\circ C$ was infered to be about 110 minutes after the start of experiment.

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Epicenter Estimation Using Real-Time Event Packet of Quanterra digitizer (Quanterra 기록계의 실시간 이벤트 패킷을 이용한 진앙 추정)

  • Lim, In-Seub;Sheen, Dong-Hoon;Shin, Jin-Soo;Jung, Soon-Key
    • Geophysics and Geophysical Exploration
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    • v.12 no.4
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    • pp.316-327
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    • 2009
  • A standard for national seismological observatory was proposed on 1999. Since then, Quanterra digitizer has been installed and is operating on almost all of seismic stations which belong to major seismic monitoring organizations. Quanterra digitizer produce and transmit real-time event packet and data packet. Characteristics of event packet and arrival time of each channel's data packet on data center were investigated. Packet selection criteria using signal to noise ratio (hereafter SNR) and signal period from real-time event packet based on 100 samples per second (hereafter sps) velocity data were developed. Estimation of epicenter using time information of the selected event packet were performed and tested. A series of experiment show that event packets were received approximately 3~4 second earlier than data packets and the number of event packet was only 0.3% compare to data packets. Just about 5% against all of event packets were selected as event packet were related P wave of real earthquake. Using the selected event packets we can estimate an epicenter with misfit less than 10 km within 20 sec for local earthquake over magnitude 2.5.

Dietary Factors Associated with Attention Deficit Hyperactivity Disorder (ADHD) in School-aged Children (학동기 어린이 주의력결핍 과잉행동장애에서 식이요인의 역할 규명)

  • An, Minji;An, Hyojin;Hwang, Hyo-Jeong;Kwon, Ho-Jang;Ha, Mina;Hong, Yun-Chul;Hong, Soo-Jong;Oh, Se-Young
    • Korean Journal of Community Nutrition
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    • v.23 no.5
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    • pp.397-410
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    • 2018
  • Objectives: An association between dietary patterns and mental health in children has been suggested in a series of studies, yet detailed analyses of dietary patterns and their effects on ADHD (attention deficit hyperactivity disorder) are limited. Methods: We included 4569 children who had dietary intake data as part of the CHEER (Children's Health and Environmental Research) study conducted nationwide from 2005 to 2010. We assessed ADHD (Attention Deficit Hyperactivity Disorder) by the DuPaul's ADHD Rating Scales and dietary intake by a semi-quantitative food frequency questionnaire. Using intake data, we constructed five dietary patterns: "Plant foods & fish," "Sweets," "Meat & fish," "Fruits & dairy products," and "Wheat based." Results: The overall proportion of ADHD was 12.3%. Boys (17.8%) showed a higher rate of ADHD than girls (6.5%). The total intake of calories (85 kcal) and plant fat (2g) in the ADHD group was significantly higher than that of the normal group. ADHD was significantly negatively associated with dietary habits such as having breakfast and meal frequency, and positively associated with eating speed, unbalanced diet, overeating, and rice consumption. Regarding dietary patterns, the "Sweets" category was relevant to high ADHD risk (OR 1.59, 95% CI: 1.18, 2.15 for Q5 vs. Q1) in a linear relationship. An inverse, non-linear association was found between "Fruits & dairy products" and ADHD (OR 0.55, 95% CI: 0.39, 0.76 for Q4 vs. Q1). Conclusions: Our study confirms both positive and negative associations between diet and ADHD in elementary school age children. Moreover, linear or nonlinear associations between diet and ADHD draw attention to the possible threshold role of nutrients. Further studies may consider characteristics of diet in more detail to develop better intervention or management in terms of diet and health.

Investigation on Granger Causality between Economic Growth and Demand for Electricity in Korea: Using Quarterly Data (한국의 경제성장과 전력수요간의 인과성에 관한 연구: 분기별 자료를 이용하여)

  • Baek, Moon-Young;Kim, Woo-Hwan
    • The Korean Journal of Applied Statistics
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    • v.25 no.1
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    • pp.89-99
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    • 2012
  • This study investigates the Granger-causality between economic growth and demand for electricity in Korea, using two quarterly time-series data (real GDP and electricity consumption) for 1970:Q1 through 2009:Q4. We apply Hsiao's sequential procedure to identify a vector autoregressive model to a decision of the optimal lags in the vector error-correction model because the two time-series data contain unit roots respectively and they are cointegrated. According to the empirical results in this study, we find that Hsiao's approach to the Granger-causality indicates a bidirectional causal relation between economic growth and demand for electricity in Korea. Following the Granger and Engle's approach, we also find the statistical evidence on (1) short-run bidirectional causality between real GDP and electricity consumption, (2) bidirectional strong causality between them, and (3) long-run unidirectional causality running from demand for electricity to economic growth. Our results show an inconsistency with the existing studies on Korea's case; however, the results appear to provide more meaningful policy implications for the Korean economy and its strategy of sustainable growth.

Simulations of the Effect of Flow Control and Phosphate Loading on the Reduction of Algae Biomass in Gangjeong-Goryong Weir (유량 조절과 인 부하 변동에 따른 강정고령보 조류저감 효과 수치 모의)

  • Park, Dae-Yeon;Kim, Sung-Jin;Park, Hyung-Seok;Chung, Se-Woong
    • Journal of Environmental Impact Assessment
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    • v.28 no.6
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    • pp.507-524
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    • 2019
  • The purpose of this study was to validate the EFDC model for the weir pool of Gangjeong-Goryong Weir located in Nakdong River, and evaluate the effect of flow control and phosphate loading reduction on the water quality and algae biomass by group (Diatom, Green, Cyanobacteria). As a result of model validation using 2018 experimental data,the time series of water level and vertical distribution of water temperature, DO, organic matter, nitrogen, and phosphorus time series were properly simulated. Seasonal fluctuations of algae biomass by group were adequately reproduced, but the deviations between measured and simulated values were significant in some periods. As a result of scenario simulations to control the water level and flow rate, the thermal stratification was resolved as the water level was lowered and the flow rate increased. The flow velocity at which the water temperature stratification was resolved was about 0.1 m/s, which is consistent with the previous study results of Baekje Weir in Geum River. Simulations of the 2Q flow scenario showed that Chl-a decreased by 8.7% and the cell density of diatom and green algae declined. The cell density of cyanobacteria increased, however, because the high concentrations of cyanobacteria in the upstream boundary conditions directly affected downstream due to increased flow velocity. In the scenario simulation of reducing the influent phosphate load concentration (average 0.056 mg/L) to 50%, Chl-a decreased by 13.6%.The results suggest that the upstream algae concentration and phosphorus load reduction should be considered simultaneously with hydraulic control to prevent algal overgrowth of Gangjeong-Goryong Weir.

Detrending Crop Yield Data for Improving MODIS NDVI and Meteorological Data Based Rice Yield Estimation Model (벼 수량 자료의 추세분석을 통한 MODIS NDVI 및 기상자료 기반의 벼 수량 추정 모형 개선)

  • Na, Sang-il;Hong, Suk-young;Ahn, Ho-yong;Park, Chan-won;So, Kyu-ho;Lee, Kyung-do
    • Korean Journal of Remote Sensing
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    • v.37 no.2
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    • pp.199-209
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    • 2021
  • By removing the increasing trend that long-term time series average of rice yield due to technological advancement of rice variety and cultivation management, we tried to improve the rice yield estimation model which developed earlier using MODIS NDVI and meteorological data. A multiple linear regression analysis was carried out by using the NDVI derived from MYD13Q1 and weather data from 2002 to 2019. The model was improved by analyzing the increasing trend of rime-series rice yield and removing it. After detrending, the accuracy of the model was evaluated through the correlation analysis between the estimated rice yield and the yield statistics using the improved model. It was found that the rice yield predicted by the improved model from which the trend was removed showed good agreement with the annual change of yield statistics. Compared with the model before the trend removal, the correlation coefficient and the coefficient of determination were also higher. It was indicated that the trend removal method effectively corrects the rice yield estimation model.

A Study on Demand Forecasting Change of Korea's Imported Wine Market after COVID-19 Pandemic (코로나 팬데믹 이후 국내 수입와인 시장의 수요예측 변화 연구)

  • Jihyung Kim
    • The Journal of Bigdata
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    • v.8 no.2
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    • pp.189-200
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    • 2023
  • At the beginning of the COVID-19 pandemic, Korea's wine market had shrunk as other countries. However, right after the pandemic, Korea's imported wine consumption had been increased 69.6%. Because of the ban on overseas travel, wine was consumed in the domestic market. And consumption of high-end wines were increased significantly due to revenge spending and home drinking. However, from 2022 Korea's wine market has begun to shrink sharply again. Therefore this study forecasts the size of imported wine market by 2032 to provide useful information to wine related business entities. KITA(Korea International Trade Association)'s 95 time-series data per quarter from Q1 of 2001 to Q3 of 2023 was utilized in this research. The accuracy of model was tested based on value of MAPE. And ARIMA model was chosen to forecast the size of market value and Winter's multiplicative model was used for the size of market volume. The result of ARIMA model for the value (MAPE=10.56%) shows that the size of market value in 2032 will be increased up to USD $1,023,619, CAGR=6.22% which is 101% bigger than its size of 2023. On the other hand, the volume of imported wine market (MAPE=10.56%) will be increased up to 64,691,329 tons, CAGR=-0.61% which is only 15.12% bigger than its size of 2023. The result implies that the value of Korea's wine market will continue to grow despite the recent decline. And the high-end wine market will account for most of the increase.

Synthesis and 3D-QSARs Analyses of Herbicidal O,O-Dialkyl-1-phenoxyacetoxy-1-methylphosphonate Analogues as a New Class of Potent Inhibitors of Pyruvate Dehydrogenase

  • Soung, Min-Gyu;Hwang, Tae-Yeon;Sung, Nack-Do
    • Bulletin of the Korean Chemical Society
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    • v.31 no.5
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    • pp.1361-1367
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    • 2010
  • A series of O,O-dialkyl-1-phenoxyacetoxy-1-methylphosphonate analogues (1~22) as a new class of potent inhibitors of pyruvate dehydrogenase were synthesized and 3D-QSARs (three dimensional qantitative structure-activity relationships) models on the pre-emergency herbicidal activity against the seed of cucumber (Cucumus Sativa L.) were derived and discussed quantitatively using comparative molecular field analysis (CoMFA) and comparative molecular similarity indeces analysis (CoMSIA) methods. The statistical values of CoMSIA models were better predictability and fitness than those of CoMFA models. The inhibitory activities according to the optimized CoMSIA model I were dependent on the electrostatic field (41.4%), the H-bond acceptor field (26.0%), the hydrophobic field (20.8%) and the steric field (11.7%). And also, it was found that the optimized CoMSIA model I with the sensitivity to the perturbation ($d_q{^{2'}}/dr^2{_{yy'}}$ = 0.830) and the prediction ($q^2$ = 0.503) produced by a progressive scrambling analyses were not dependent on chance correlation. From the results of graphical analyses on the contour maps with the optimized CoMSIA model I, it is expected that the structural distinctions and descriptors that subscribe to herbicidal activities will be able to apply new an herbicide design.

A Study on the Integrated Computer Program for the Multi Analysis of In-Situ Aquifer and Geothermal Response Test (현장 열응답시험과 현장 대수성시험결과를 동시 분석 가능한 통합전산 Program에 관한 연구)

  • Hahn, Jeong-Sang;Han, Hyuk-Sang;Yonn, Yun-Sang
    • Journal of the Korean Society for Geothermal and Hydrothermal Energy
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    • v.4 no.1
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    • pp.11-19
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    • 2008
  • Groundwater flow in confined aquifer and heat transport in underground geologic media are using same governing equation(line source) like well fuction. Therefore the conventional slope method using only later data obtained from in-situ thermal response test to determine the thermal conductivity of vertical geothermal heat exchanger(GHEX) is basically identical with one of Theis straight line method of aquifer test under artesian condition. In case that the pumping rate(Q, $m^3$/d) and drawdown(s,m) which are used for input data of existing hydrogeologic computer programs for aquifer test are replaced and converted to supplying heat energy per unit length of bore hole(Q/L,w/m or Kcal/h.m) and temperatures (T,$^{\circ}C$)measured at in and out-let of GHEX as in put data respectively, thermal conductivity around geothermal heat exchanger can be easily estimated without any special modification of the existing hydrogeologic computer program. Two numbers of time series temperature variation data obtained from in situ geothermal response test are analized using Theismethods(standard curve and straight line method) by using existing aquifer test program and conventional Slope method proposed by ASHRAE. The results show that thermal conductivity values estimated by two straight methods are identical and the difference of estimated values between standard curve methods and Slope method are also within acceptable ranges. In general,the thermal conductivity estimated from Theis straight linemethod gives more accurate value than the one of Slope method due to that Slope method uses only visual matching otherwise Theis method uses automatic curve matching estimation with reducing RSS.

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