• 종양간호연구
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• 제11권1호
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• pp.26-32
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• 2011

Purpose: The purpose of this study was to analyze the trend of cognitive developmental interventions on patients with breast cancer who underwent chemotherapy. Methods: The researcher searched databases and selected 17 literatures using chemotherapy, breast cancer, cognitive function and intervention as searching key words. Searched databases included Ovid, Pubmed, Proquest and Medline and data collection period was from January 2000 to May 2010. Results: Interventions for patients with breast cancer have been continuously developed and frequent research topics included breast cancer, chemotherapy, quality of life, and cognitive function. In terms of study design, four research articles were pre-experimental study designs, one was case study, and the rest of studies were non-equivalent pretest-posttest control group design. Effects of intervention were examined in only 5 studies among 17. The interventions were not found to have direct effects in cognitive improvement. Conclusion: It is needed to figure out the mechanism of cognitive deterioration of the patients with breast cancer who underwent chemotherapy. And nursing interventions needs to be developed in order to hold up the cognitive downhill and help their cognitive rehabilitation.

• 한국환경보건학회지
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• 제37권6호
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• pp.397-405
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• 2011

Objectives: The impact of climate change on the health has been of increasing concern due to a recent temperature increase and weather abnormality, and the research results of the impact varied depending on regions. We synthesized risk estimates of the overall health effects of low and high temperature taking account of the heterogeneity. Methods: A comprehensive literature search was conducted using PUBMED to identify journal articles of low and/or high temperature effects on mortality. The search was limited to the English language and epidemiological studies using time-series analysis and/or case-crossover design. Random-effect models in meta analysis were used to estimate the percent increase in mortality with $1^{\circ}C$ temperature decrease or increase with 95% confidence intervals (CI) in cold or hot days. Results: Twenty three studies were presented in two tables: 1) low temperature effects; 2) high temperature effects on mortality. The combined effects of low and high temperatures on total mortality were 2% (95% CI, 1-4%) per $1^{\circ}C$ decrease and 4% (95% CI, 2-5%) per $1^{\circ}C$ increase of temperature, respectively. Conclusions: This meta analysis found that both low and high temperatures affected mortality, and the magnitude of high temperature appeared to be stronger than that of low temperature.

• 대한한의진단학회지
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• 제10권1호
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• pp.46-53
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• 2006

Magnetocardiography provides non-invasive three-dimensional electroanatomical imaging of cardiac electrophysiology. The aim of this study is to find the index for using the indicator of magnetocardiography. An object of this study is 214 papers registered on www.pubmed.com. The index used in magnetocardiography is the interval, morphology, amplitude and integrals of QRS complex, P wave, T wave. The current density and electric field map are used, too. A new try of the index is LAS, W-HEAD, Relative Smoothness index(RS index) etc.

• 대한암한의학회지
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• 제17권1호
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• pp.27-38
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• 2012

Objective : To present an overview of current reports and guidelines of physical activity and exercise intervention for cancer survivors Methods : We searched Pubmed for the related studies such as randomized controlled trials and observational studies, as well as published guidelines or recommendations for exercise intervention. Results : Physical activity and exercise intervention is considered safe and effective for most cancer survivors. According to the guidelines, patients with peripheral neuropathy, musculoskeletal disorder, or those who are at risk of fracture, should undergo proper medical assessment before starting exercise intervention. Also, patients with bone metastasis, thrombocytopenia, symptomatic anemia, or acute infection may fall into one of the contraindications of exercise intervention. Conclusions : Physical activity and exercise intervention may play a major role in improving physical functioning, quality of life, or treatment-related symptoms of cancer survivors. It is necessary to recognize the benefits and precautions of exercise in caring cancer patients.

• 대한한방내과학회지
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• 제31권3호
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• pp.448-456
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• 2010

Objective : To summarize and make a reference number of antihyperlipidemic herbal plants worldwide. Method : We surveyed all papers of antihyperlipidemic studies using herbal plants in Pubmed database as "hyperlipidemia AND herb", "hyperlipidemia AND herbal", etc. of Default Tag "Title". The number of papers, the formation of experiments, frequency of herbal plants studies, and main studies were analyzed. Result : Total 178 studies were finally selected. The number of papers were rapidly was increased since 1998. RCT studies were most papers(39.9%). Most studies were about plant sterol or plant stanol studies(78%). 10 papers studied about Herbal plants. Crataegus pinnatifida Bunge, Salvia miltiorrhiza Bunge, Alisma orientale(Sam.) Juz. and so forth were relatively studied much. Conclusion : This study produced an overview of worldwide antihyperlipidemic plants. This result may provide a valuable information for development of Korean herbal medicine against hyperlipidemia in the future.

• 동의신경정신과학회지
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• 제28권4호
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• pp.303-318
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• 2017

Objectives: To establish a base for further research by reviewing studies on traditional Chinese medicine treatment for Tourette Syndrome. This is the purpose of this study. Methods: Clinical studies involving the effects of traditional Chinese medicine treatment for Tourette Syndrome, published January 2010~June 2017, were obtained from CNKI, Pubmed. Selected Studies were evaluated by the Jadad Scale. Results: Among a total of 252 articles, 39 articles that meet the criteria were selected. 'Diagnostic and Statistical Manual for Mental Disorders, 4th edition (DSM-IV)' was most frequently used as diagnosis criteria. 'Yale Global Tic Severity Scale (YGTSS)' was primarily used for outcome measurements. Most of the studies showed effective results of traditional Chinese medicine therapy. However, the quality of a selected clinical studies was low. Conclusions: Despite several limitations, various studies to prove limited yet effective traditional Chinese medicine treatment on Tourette Syndrome provides much significance. Subsequent studies conducted by the complementary systematic review and well-designed clinical trials using the methodological quality will be needed to more firmly validate the effect of traditional Chinese medicine therapy.

• 보건의료산업학회지
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• 제5권4호
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• pp.161-175
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• 2011

The purpose of this study was to expand the home-based rehabilitation services in the long term care insurance. This study was reviewed on the home-based physical therapy in the OECD. The way of this study was literature search and review. This was to reviewed Proquest, Sciencedirect, SpingerLink, Pubmed. Kew word is "home-based therapy". This was collected 71 articles and final analyzed article was 49. The results were as follows; The article number is seven in Canada, fifteen in USA, five in UK, six in Australia, three in Sweden, five in New Zealand, two in Netherlands, one in Turkey, South Korea, Japan, France, Spain, Italy respectively. Randomized controlled trial is fifty, case-control study is eleven, interview is three, literature review is two, and case report, cost-analysis, cost-effectiveness, pilot study, single blinded parallel design, demonstrative study, survey is one respectively. Physical therapist played an important role in home-based rehabilitation among OECD than nurse. Therefore, we must introduce home-based physical therapy in long term care insurance in South Korea.

• 대한한의학회지
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• 제41권1호
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• pp.93-106
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• 2020

Objectives: The aim of this review is to ascertain whether Bojungikgi-tang and its modifications is more effective than non-specific management in chronic fatigue syndrome (CFS). Methods: We collected clinical trials to investigate the effects of Bojungikgi-tang and non-specific management on general symptoms, fatigue, and sleep quality in CFS patients. The databases used for data retrieval were Pubmed, Central Cochrane, CNKI, VIP, CiNii, OASIS, RISS, and Koreamed. We performed selection/exclusion process from the found records according to prespecified criteria, and assessed the final included trials according to the Cochrane risk of bias tool. The included studies were classified on the basis of interventions in experimental group. Results: Seven randomized controlled trials (476 participants) were eligible and their results were synthesized in the meta-analysis. The synthesis showed a substantial effect of Bojungikgi-tang (relative risk 0.20 [95% CI 0.13 to 0.31], Z=7.44, P<0.00001; I²=0%) and combination of Bojungikgi-tang and Sosiho-tang (relative risk 0.15 [95% CI 0.08 to 0.28], Z=5.85, P<0.00001; I²=0%) compared with non-specific management on improvement of general symptoms. However, we could not find sufficient clinical research records to determine their effects of improvement on fatigue and sleep quality. Conclusions: Bojungikgi-tang and its modifications are more effective than non-specific management for improvement of general symptoms in CFS post-treatment.

• 대한한의학회지
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• 제41권1호
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• pp.107-116
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• 2020

Objectives: To overcome the limitations of randomized controlled trials, many other trials design is tested. The n-of-1 trial is a promising research method in the field of Korean medicine because of this methodology can examine the optimal treatment for each patient strictly. Therefore, we reviewed the status of N-of-1 studies on herbal medicine. Methods: A systematic literature review was conducted based on the pubmed database. The search term were 'N-of-1 Trial', 'Chinese Medicine', 'Herbal Medicine', 'Kampo'. There was no restriction in year. Results: Four clinical trials have been identified to demonstrate the effectiveness of herbal medicines for Kidney-yin-deficiency syndrome, bronchiectasis and gastric cancer. These studies suggest that the N-of-1 design is a study that encourages patient involvement, demonstrates the effectiveness of herbal medicines and helps reduce unnecessary medication. Conclusion: The N-of-1 clinical trial may be a rigorous methodology suitable for the clinical setting and may help the development of evidence-based Korean medicine. Attention is also needed in this research method in Korea.

• 대한한의학회지
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• 제41권3호
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• pp.247-259
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• 2020

Objectives: This review aims to investigate clinical studies related to bee venom pharmacopuncture for cancer patients and to analyze the research trend for further study. Methods: We searched for clinical studies using bee venom pharmacopuncture therapy on patients with cancer through the electronic databases including Pubmed, Cochrane library, OASIS, KISS, NDSL, and KMBASE. There was no restriction on language and publication date, and after selection/exclusion process, the study design, target disease, intervention details including acupoints, treatment frequency and period, outcomes, study results and adverse events were extracted. Results: Thirteen clinical studies were finally selected. There were a randomized controlled trial RCT about the effect of sweet bee venom pharmacopuncture on cancer-related pain, and three case series about chemotherapy-induced peripheral neuropathy. In case reports, there were nine studies about oligodendroglioma, plexiform neurofibroma, breast cancer, prostate cancer, lung cancer, urachal adenocarcinoma, malignant melanoma, and atypical squamous cells of undetermined significance. The bee venom therapy affected the improvement of outcomes such as symptoms, quality of life, tumor response, and lab findings. Conclusions: The present study found that bee venom therapy is applicable to the treatment of cancer patients, and showed some effect on various symptoms. However, due to insufficient number and quality of studies, well designed and high-quality clinical trials are necessary to confirm the effectiveness and safety of bee venom pharmacopuncture therapy in patients with cancer.