• 한국간호교육학회지
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• 제25권2호
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• pp.263-272
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• 2019

Purpose: The purpose of this study was to identify the moderating effect of interpersonal skills on the relationship between childhood emotional trauma and depression. Methods: From June to July, 2017, a convenience sample of 226 nursing students was recruited. Research data were collected through self-report questionnaires and analyzed using SPSS version 22.0. Results: 68.1% (154) respondents experienced emotional abuse, and 48.1% (110) emotional neglect in childhood emotional trauma. The average depression score was 10.76. There were 54.4% (123), 34.5% (78), 12.8% (29), and 7.1% (16) of respondents with mild, moderate, and severe depression, respectively. The average interpersonal skills score was 3.59. There was a significant correlation between childhood emotional trauma (emotional abuse, emotional neglect), interpersonal skills and depression. And the moderating effect of interpersonal skills on the relationship between childhood emotional neglect and depression was significant. Conclusion: Interpersonal skills play a role as a moderating variable influencing the relationship between emotional neglect of childhood emotional trauma and depression, and also reduce the effects of childhood emotional trauma on depression. When developing a depression prevention program for nursing college students, such programs should consider strategies to reduce the negative effects of childhood emotional trauma and to improve interpersonal skills.

• 산업진흥연구
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• 제3권2호
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• pp.41-51
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• 2018

본 연구는 아동학대문제를 사회문제로 보고, 이는 사회 전체가 해결점을 찾아야 할 사안임을 직시하고 그 해결방안을 제시하고자 한다. 본 연구 결과는 다음과 같다. 첫째, 법적 보완이 우선되어야 한다. 이는 관련 법률에 대한 입법 및 법 개정을 통한 법적 보완으로 해결할 수 있다. 둘째, 제도적 보완이 이루어져야 한다. 피학대아동에게 학교교육보다는 신체적 심리적 치료가 절실하다. 향후 아동복지시설은 양육시설보다는 가정에서 살고 있지만 문제행동을 하는 아동을 위한 아동상담소와 전문적 치료가 필요한 아동을 위한 치료형 보호시설을 확충해야 한다. 셋째, 학대피해아동에 대한 조치가 뒤따라야 한다. 피해아동을 대상으로 하는 조치결과에는 원가정보호, 분리보호, 가정복귀, 사망이 있다.

• Biomolecules & Therapeutics
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• 제21권4호
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• pp.307-312
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• 2013

Quetiapine is an atypical or second-generation antipsychotic agent and has been a subject of a series of case report and suggested to have the potential for misuse or abuse. However, it is not a controlled substance and is not generally considered addictive. In this study, we examined quetiapine's dependence potential and abuse liability through animal behavioral tests using rodents to study the mechanism of quetiapine. Molecular biology techniques were also used to find out the action mechanisms of the drug. In the animal behavioral tests, quetiapine did not show any positive effect on the experimental animals in the climbing, jumping, and conditioned place preference tests. However, in the head twitch and self-administration tests, the experimental animals showed significant positive responses. In addition, the action mechanism of quetiapine was found being related to dopamine and serotonin release. These results demonstrate that quetiapine affects the neurological systems related to abuse liability and has the potential to lead psychological dependence, as well.

• 대한핵의학회지
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• 제27권1호
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• pp.22-27
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• 1993

Drug abuse is widespread in worldwide and has been associated with neurologic complication. Zipeprol is one of the drugs which been abused for psychological satisfaction in some adolescents. This agent is non-opioid antitussive agent, which is not legally considered as being capable of creating dependence or abuse liability at therapeutic serum levels. But it has been reported that acute or chronic overdose create neurologic complication such as convulsion as well as dependence. Recently we experienced six zipeprol abusers who admitted due to convulsion and variable neurologic symptoms. The aim of our study was to determine the role of $^{99m}Tc$-HMPAO brain SPECT in those patients. EEG and brain CT showed no abnormal finding, but brain SPECT showed focal or multiple perfusion abnormalities in frontal, parietal, occipital cortex, basal ganglia, thalamus and especially at temporal cortex. These results suggest that brain SPECT may be a useful diagnostic tool to evaluate the cerebral dysfunction infused by zipeprol abuse.

• Biomolecules & Therapeutics
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• 제22권6호
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• pp.558-562
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• 2014

Tramadol is an opioid analgesic agent that has been the subject of a series of case reports suggesting potential for misuse or abuse. However, it is not a controlled substance and is not generally considered addictive in Korea. In this study, we examined the dependence potential and abuse liability of tramadol as well as its effect on the dopaminergic and serotonergic systems in rodents. In animal behavioral tests, tramadol did not show any positive effects on the experimental animals in climbing, jumping, and head twitch tests. However, in the conditioned place preference and self-administration tests, the experimental animals showed significant positive responses. Taken together, tramadol affected the neurological systems related to abuse liability and has the potential to lead psychological dependence.

• 한국사회복지학
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• 제61권2호
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• pp.277-301
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• 2009

본 연구의 목적은 남성 폭력행위자의 부부갈등 대처전략이 아내폭력에 미치는 영향을 규명하는 데 있다. 이를 위해 전국 가정폭력상담소14개소에서 가정폭력 문제로 상담을 받기 시작한 남성 폭력행위자를 대상으로 설문조사를 실시하여 회수한 설문지 121부 모두를 본 연구의 분석에 사용하였다. 위계적 다중회귀분석을 실행한 결과, 남성 폭력행위자의 부부갈등 대처전략은 심리적 신체적 아내폭력에 유의미한 영향을 미치는 것으로 나타나서, 문제해결 대처전략을 사용하지 않을수록 심리적 폭력의 빈도가 유의미하게 증가했으며, 회피대처 전략을 사용할수록 신체적 폭력의 빈도가 유의미하게 증가했다. 또한 결혼만족도가 낮을수록 심리적 신체적 아내폭력의 빈도가 증가하고, 적대감이 높을수록, 음주문제 정도가 심각할수록 심리적 아내폭력의 빈도가 증가하는 것으로 밝혀져서, 결혼만족도, 적대감, 음주문제 정도가 아내폭력에 유의미한 영향을 미치는 요인임을 규명하였다. 이와 같은 연구결과는 부부갈등 대처전략이 아내폭력의 발생에 영향을 미치는 요인으로서 행위자 대상의 치료프로그램에서 적극적으로 다루어져야 할 주제임을 보여 주는 것이라 할 수 있다. 또한 가정폭력 문제의 개입에서 행위자의 음주문제를 포함한 정신건강 증진과 전반적인 결혼의 질 향상을 포함하는 포괄적인 개입이 이루어질 필요성이 있음을 제시한 것이라 할 수 있다.

• 가정과삶의질연구
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• 제21권6호
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• pp.53-67
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• 2003

The aim of this research is to verify the assumption that the husband-to-wife violence lies upon a continuum of severity and to study how the premarital violence experience of husbands, along with their psychological characteristics and various marital interactions, can be the cause of husbands' violence against their wives. At the same time, the research aims at constructing a causal model of the husband-to-wife violence. For the purpose, this research surveyed 242 husbands residing in Pusan and another 50 husbands as violent assaulters in major cities of Korea. The following is a summary of the results of this research. First, the research can verify the two assumptions that “the group which has once inflicted a severe form of violence can easily inflict minor violences” and that “the factors related to violence play a far greater role in severe violences than in weaker violences.” As a result, it may be concluded that the study of a regular household violence can be based on the continuum of violence assumption. Secondly, In the husbands' experience of violence, dating violence and their experienced childhood abuse from their parents, in their psychological characteristics, temper control ability and their patriarchal sex role attitude, and finally in marital interactions, marital conflicts and distractor of communication played great role in their influence on the husband-to-wife violence. Thirdly, as the various factors which contribute to the violence against the wife have cause-and-effect rule, we shall be able to make a model which can be conceptualized.

• Archives of Pharmacal Research
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• 제26권7호
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• pp.540-544
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• 2003

Morphine, an analgesic with significant abuse potential, is considered addictive because of drug craving and psychological dependence. It is reported that repeated treatment of morphine can produce conditioned place preference (CPP) showing a reinforcing effect in mice. CPP is a useful method for the screening of morphine-induced psychological dependence. In the present study, we investigated the effect of the methanolic extract of Coptis japonica (MCJ) on morphine-induced CPP in mice. Furthermore, we examined c-fos expression in the parietal cortex, piriform cortex, striatum, nucleus accumbens, and hippocampus of the morphine-induced CPP mouse brain. Treatment of MCJ 100 mg/kg inhibited morphine-induced CPP. Expression of c-fos was increased in the cortex, striatum, nucleus accumbens, and hippocampus of the morphine-induced CPP mouse brain. These increases of expression were inhibited by treatment with MCJ 100 mg/kg, compared to the morphine control group. Taken together, these results suggest that MCJ inhibits morphine-induced CPP through the regulation of c-fos expression in the mouse brain.

• Biomolecules & Therapeutics
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• 제16권2호
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• pp.113-117
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• 2008

Morphine is a potent analgesic with significant abuse potential, because of drug craving and psychological dependence. It is reported that repeated treatment of morphine can produce conditioned place preference (CPP) showing a reinforcing effect in mice. Previously, we have reported the inhibitory effect of the methanolic extract of Coptis japonica (MCJ) on morphine-induced CPP in mice. The present study was employed whether p-CREB expression is involved in the inhibitory effect of MCJ on the morphine-induced CPP in the mouse hippocampus. Repeated administration of MCJ 100 mg/kg inhibited morphine-induced CPP. Expression of p-CREB was increased in the dentate gyrus of the hippocampus that had undergone morphineinduced CPP. This increase of expression was significantly inhibited by administration of MCJ 100 mg/kg, compared to the morphine control group. Taken together, these results suggest that MCJ inhibits morphine-induced CPP through the regulation of p-CREB expression in the mouse dentate gyrus of the hippocampus.

• 한국병원경영학회지
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• 제25권3호
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• pp.1-13
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• 2020

Purpose: This study was conducted to identify the conceptual definition and attributes of 'Taeoom' (or workplace bullying) inflicted to newly employed nurses in Korea. Method: Walker & Avant(2011)'s eight-stage process was used to perform a conceptual analysis of 'Taeoom'. Literature review of 40 studies published between Jan. 2009 and March 2018 published in Korea was followed by the in-depth interview with nine newly employed hospital nurses and the ex-post review of results by nursing experts. Findings: 'Taeoom' was associated with five attributes: (1) bullying for no reason, (2) peer rejection for no reason, (3) decreased physical function and psychological withdrawal, and (4) verbal abuse, defamation and nagging, (5) impotent feeling due to power imbalance. Four antecedents found in this study include offensive action, distrust, power imbalance, and undue workload exceeding capacity. As consequences of Taeoom, negative physical and psychological symptoms and turnover intention were increased while nursing performance was decreased. Conclusion: This study suggests the need for more qualitative researches with more comprehensive approach on Taeoom and the development of effective program to improve the organizational culture in nursing field. This study is significant in that it provides a qualitative but comparative review on the attributes, antecedents and consequences of Taeoom through literature review accompanied by focus group interview and expert review.