• 근관절건강학회지
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• 제6권1호
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• pp.22-36
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• 1999

The purpose of the study was to identify disease characteristics and behavior pattern of treatment for patients with Fibromyalgia. This study was carried out between May to Aug. in 1998 through direct interview in Rheumatism clinic at H. University Hospital and subject in this study were 125 outpatients diagnosed with Fibromyalgia. Collected data were analyzed by descriptive statistics and t-test, ANOVA using SPSS Window program. The results of this study are as follows. 1. General Characteristics : All of the persons with Fibromyalgia were female who were mostly in their forties(37.5%). A third of them(38.4%) were graduated from high school. The greatest part of them(54.4%) were christians but little part of them(16.8%) were employed 2. Disease Characteristics : They have struggled with Fibromyalgia for 10 years on an average. About half of them(56.9%) suffered from Fibromyalgia only but the others had another diseases which were in greatest part occupied by Osteoarthritis. The number of tender point which is a feature of Fibromyalgia differed according to measuring criteria. Yunus criteria. however, was proved to be the most proper measuring criteria than any other method as it showed high correlations between symptoms and physical activities. The most serious symptoms that complained the patients among subjective symptoms are pain, sleep disorder, and fatigue in sequence, and activities most hard to do among physical activities are washing by hand, scrubbing by hand, and shopping in sequence. 3. Behavior Pattern of Treatment : The largest part of them(42.4%) had received medical treatment after they were determined to have the disease and most of them were taking medicine as prescribed by physician(88.8%) or other medicines(16.8%), Of them, two thirds stated that the medicine they took were effective. Around a third of them took exercises mostly composed of swimming. The medical institution they visited in the past were orthopedic surgical department, Oriental hospital, physical therapy department in sequence and, in a slight percent(11.4%), psychiatric department. 4. Relations between Disease Characteristics and Behavior pattern of Treatment : It shows that number of tender point and level of symptom are significantly different according to duration of disease and medical intervention. As a results, it can be suggest that persons with Fibromyalgia need to take exercises and medicine continually regardless of medical treatment as it is a chronic disease whose symptoms are hardly mitigated.

• 정신신체의학
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• 제22권2호
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• pp.87-92
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• 2014

연구목적 본 연구에서는 섬망의 오진과 관련된 임상적 특징 및 임상의를 오진으로 유도할 수 있는 증상적 특징들을 알아보고자 한다. 방 법 일 대학병원에 입원하여 정신과에 협의진료 의뢰된 환자 중, 정신건강의학과 전문의에 의해 섬망으로 진단된 256명을 대상으로 후향적으로 의무기록을 조사하였다. 협진요청서에 명시된 사유를 검토하여, 의뢰의사의 진단이 섬망인 경우 진단일치군으로 섬망이 아닌 경우 진단불일치군으로 구분하였다. 결 과 69명(27%)이 진단불일치군으로, 섬망이 아닌 다른 진단으로 협진이 의뢰되었다. 진단불일치군에서 항정신병약물의 사용, 기질성 정신질환의 과거력이 많았다. Delirium rating scale-Revised-98(DRS-R-98) 중 증상의 변동 항목의 점수가 진단일치군에서 더 높았다. 로지스틱 회귀분석결과 질환의 낮은 심각도, 항정신병약물 사용력, 적은 증상의 변동이 임상의가 섬망 외에 다른 진단을 고려하는 예측인자였다. 결 론 본 연구에서 항정신병약물을 복용중인 경우, 섬망증상의 변동이 적은 경우 오진의 위험이 높았다. 지연된 섬망의 진단과 치료는 환자의 예후에 부정적인 영향을 미칠 수 있으므로 주의 깊은 임상적 관심이 필요하다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제10권1호
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• pp.34-42
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• 1999

본 연구는 정서 행동적 문제를 자주 동반하는 것으로 알려진 아토피피부염 소아 청소년에 대해, 정신과적 문제의 정도와 병변 심각도에 영향을 미칠 수 있는 심리 사회적요인을 알아보고자 하였다. 서울대학교병원 아토피 크리닉을 방문한 아토피피부염 환자 70명(평균 나이 9.9세, 범위：$4{\sim}15$세)과 그 어머니를 대상으로 병력조사설문지, CBCL, MBRI, CDI, STAI을 주어 완성하도록 한 후, 정신과적 면담을 시행하였다, 환자의 피부 병변에 대해 SCORAD index를 이용하여 침범부위, 병변의 경중도, 주관적 증상으로 나누어 평가하였다. 16명(22.9%)이 임상적으로 유의한 정서 행동적 문제가 있을 것으로 예측되었으며 이들은 우울, 특성 불안, 어머니의 통제적 태도, 부정적평가 척도에서 다른 아토피 군보다 점수가 높았다. 병변의 경중도는 특성불안이나 우울정도와, 주관적 증상은 우울, 특성불안, 가족영향, 사회능력, 내재화 및 외현화 문제, 성문제, 아이에 대한 부정적 평가와 관련이 있었다. 아토피피부염을 가진 소아 청소년은 정신과적 문제의 고위험군이며 이러한 정신과적 문제는 양육태도와 함께 피부증상의 주관적 지각에 영향을 미칠 가능성이 높다고 할 수 있다. 향후 이에 대한 정신과적 개입이 필요할 것으로 생각된다.

• 생물정신의학
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• 제8권2호
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• pp.271-275
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• 2001

60세 남자 환자로 좌측 정중 전두엽과 양측 기저절 경색 후 발생한 과잉성욕 증상과 강박 증상을 주소로 내원하였다. 환자는 뇌졸중 후에 발생한 운동 기능 장애는 시간이 경과하면서 호전되어 발병 1개월 이내에 거의 정상화된 반면 과잉성욕 증상과 강박 증상은 호전되지 않았다. 환자에게 과잉성욕 증상과 강박 증상을 목표로 fluvoxamine과 perphenazine을 처방하였으며 치료 시작 후 2개월이 경과하면서 환자의 과잉성욕 증상과 강박 증상은 서서히 사라졌다. 이 증례는 기저절-시상전두엽 회로가 성적 행동과 강박 증상의 조절에 있어 중요한 역할을 하고 있음을 시사한다고 할 수 있다. 과잉성욕 증상은 임상에서 간과하기 쉽고 또한 일반적으로 성적 활동에 대한 변화는 환자들 스스로 보고하지 않는 경향이 많다. 따라서 뇌졸중 환자, 특히 정중 전두엽이나 기저절 병변을 동반한 환자들의 경우에는 비록 그 병변이 측두엽 침범이 없거나 Kluver-Bucy syndrome의 전형적인 증상을 보이지 않는다 할 지라도 성욕등 성적 활동에 대한 체계적인 조사가 필요할 것으로 생각된다. 또한 과잉성욕 증상과 강박 증상을 함께 가지고 있는 경우 선택적인 세로토닌 재흡수 억제제의 사용이 두 증상 모두를 효과적으로 치료하는 데에 도움이 될 수 있을 것이다.

• Journal of Hospice and Palliative Care
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• 제12권4호
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• pp.177-193
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• 2009

완화의학에서 환자의 평가는 치료의 의사결정과 그 결과에 이르기까지 중요한 역할을 한다. 평가도구의 사용 목적은 이를 환자 진료에 반영하여 개개인 환자와 가족들에 대한 돌봄의 질을 높이는 데 있다. 환자의 기능 상태와 통증 및 비 통증 증상을 평가하는 다양한 단일 영역 및 다차원 평가 척도들이 사용 가능하며, 삶의 질을 측정하는 다양한 도구들이 존재한다. 삶의 질이나 증상 측정에서 우월하다고 추천되는 단일 도구는 없는 실정이다. 도구마다 측정하는 시간의 틀이 다르고, 특성이 다르므로 사용 목적과 상황에 따라 적절한 도구를 선택하여야 한다. 여명 예측을 위해서는 예후 지수의 병용이 권고되는 추세이고, 웹을 기반으로 하는 예측 프로그램들도 등장하였다. 예후지수로는 최근 우리나라에서 다기관 연구를 통해 개발한 객관적 예후지수가 임상적인 여명 예측을 포함하지 않으면서 새로운 객관적인 예후 요인을 반영하여, 누구나 쉽게 사용이 가능하다. 완화의학 입문자의 경우 상대적으로 사용이 용이한 도구가 좋다. 따라서 기능의 평가에는 Eastern Cooperative Oncology Group 기능지수를 사용하고, 통증에서는 10점만점의 숫자 통증 등급(Numeric Rating Scale) 도구를 활용하면서 초기 통증 평가로는 간이 통증 조사지를 추천한다. 여러 가지 증상을 한꺼번에 측정하기 위해서는 숫자 등급으로 직접 물어보거나 혹은 M.D. Anderson 증상조사지(the Korean version of MD Anderson Symptom Inventory) 설문지를 사용하기 바란다. 삶의 질을 평가하는데에는 European Organization Research and Treatment Quality of Life Questionnaire Core 15 for Palliative Care, 예후 지수로는 객관적 예후 지수(Objective Prognostic Score)를 사용하기를 권한다. 향후 완화의학에서 평가도구의 발전방향은 국제 공동 연구의 활성화와 디지털 기기를 통한환자 보고의 전산화이고, 머지않은 앞날에 우리나라에도 이러한 경향이 도입될 것이다.

• 보건교육건강증진학회지
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• 제19권3호
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• pp.107-120
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• 2002

There has been a rapid industrial progress in Korea since 1962 by the success of 5-year economic development plan, and the number of industrial work has also made a rapid increase. Consequently, the management of the occupational health for the purpose of promoting the health of industrial workers and improving the working environment is badly needed in these days. Health services on industrial noisy environment have been provided only for noise-induced hearing loss management until now. But gradually, modem diseases and death have come to be related to the stress and mental health, therefore noise-induced mental disorder, like a stress became very important. Thus, this study has been carried out to analyze the relationship between workers' stress symptoms and the perceived working environment and the perceived working conditions. This study included 786 industrial workers selected from II factories in Buchun. The results were as follows: 1. For demographic characteristics, most of the workers were males(75.7%), the 20～29 years old were 33.8% and those who graduated from high school were 56.1%. The workers whose monthly income ranged from 700,000 to 1,500,000 won were 37.9% and who has a religion were 49.0%. 2. For occupational characteristics, workers who had worked 5～10 years in the factories were 35.8%. Those who felt much for them workload were 42.7% and who worked more than 8 hours a day were 73.7%. Those who were dissatisfied with their pay and job were 51.1 % and 31.2%. The workers who responded ventilation condition of their worksites were bad were 50.4% and the dissatisfied with working environment of their worksites were 43.8%. 3. For the noise exposure level in worksite, workers who were exposed to 70∼90㏈ were 37.4%, 90∼100㏈ were 25.2% and 50∼70㏈ were 18.8%. 4. Workers∼ stress symptoms were significantly related to marital status and their monthly income(P〈0.05). Workers who were single and had lower monthly income showed higher PSI(Psychiatric Symptom Index) scores than those who were married and had higher monthly income. Higher PSI scores were also significantly related to the night-work, workload, dissatisfaction with their job, and bad relationship with their bosses or co-workers. 5. The higher noise exposure level in worksite from 80㏈ was, the more severe stress symptoms including PSI subparts were reported; Anxiety, Anger, Depression, and Cognitive disorder symptom(P〈0.001). 6. According to the results of stepwise multiple regression analysis, factors affecting workers' PSI scores were noise exposure level in worksite(R2=0.150), relationship with coworkers, amount of workload, monthly income and relationship with bosses orderly and the total R2 of this 6 factors was 29.7%.

• 정신신체의학
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• 제28권2호
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• pp.135-142
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• 2020

연구목적 간호사의 신체화 증상과 스트레스, 우울 및 불안, 정신 증상 위험의 관계를 확인하여 정신신체의학 연구의 임상 근거를 창출하고, 신체화 증상의 의미에 대해 제고하는 것을 목적으로 한다. 방 법 서울시 내 1개 상급종합병원 외과계 중환자실 간호사 70명에게 자가기입형 도구(Perceived Stress scale, Fatigue Severity Scale, Patient Health questionnaire-15, Korean Beck Depression Inventory, Korean Beck Anxiety Inventory, Symptom Checklist-90-Revision)를 사용하여 수집한 데이터를 분석하였다. 결 과 대상자 중 12.9%가 신체화 증상을 경험하였고 피로, 낮은 에너지, 생리통, 허리 통증이 나타났다. 신체화 증상과 정신적 스트레스 인지의 통계적 관련성은 없었으나 불안한 느낌이나, 자신감의 감소는 신체화 증상의 수준과 관련이 있었다. 신체화 증상이 심한 집단은 우울, 불안을 더 많이 경험하였다. 신체적 피로가 높은 집단은 정신적 스트레스 인지의 통계적 관련성은 없었으나 긴장이나 스트레스를 느끼거나 통제력이 감소되는 경험에 영향을 미쳤다. 신체적 피로 수준의 증가는 불안과는 관련이 없었고 우울을 더 많이 경험하는 것으로 확인되었다. 신체화 수준이 높을수록 정신 증상 중 강박과 적대감이 증가하였다. 선형회귀모형에서 스트레스, 우울, 불안은 신체화 증상을 39.3%, 신체적 피로 증상을 16.1% 설명하였다. 결 론 이 연구의 결과를 바탕으로 우리는 한국 문화에서 신체화 증상의 특징으로 스트레스 인지 증상의 감소, 우울과 불안 경험, 강박 및 적대감의 동반 가능성을 추정할 수 있다. 이 연구에서 신체화와 정신 증상은 인과관계를 확인할 수 없었으나 상호관련성이 관찰되어 향후 중재 전략 마련에 참조할 수 있을 것이다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제17권2호
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• pp.149-162
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• 2006

Objectives : This study examined psychopathology, abuse history and the relation of them in sheltered runaway adolescents. The purpose is to investigate characteristics of adolescents who are in shelters according to abuse type and then to offer basic data which are needed in establishing comprehensive protection policy for runaway adolescents. Methods : One hundred twenty eighty adolescents who stay in the runaway shelters were asked to complete self-report questionnaires including basic sociodemographic data, Korean Youth Self Report (K-YSR), Minnestota Multiphasic Personality Inventory (MMPI), and Symptom Checklist-90-Revised (SCL-90-R) and then examined the correlation of psychopathology and abuse in runaway adolescents. Results : In abused runaway adolescents, social performance scale of K-YSR was higher than school performance sealer and among scales of behavioral problem syndrome delinquent scale was highest. Scales of behavioral problem syndrome showed relatively significant correlation with abuse history. In MMPI scale of psychopathic deviate scale was highest, social introversion showed significant correlation with emotional abuse, and psychopathic deviate and hypomania showed significant correlation with physical abuse, neglect and sexual abuse. In SCL-90-R somatization scale was highest. Scales of somatization, hostility, and paranoid ideation scale were significantly high in adolescents with emotional abuse and neglect history, and scores of anxiety and depression scale were significantly high in sexually abused adolescents. Conclusion : Runaway adolescents who had abuse experience showed significantly higher level of psychopathology than general adolescents and there were various interrelations between them according to the presence and the type of abuse. More precise psychiatric evaluation and detailed treatment intervention for runaway adolescents are needed.

• 대한한방내과학회지
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• 제33권4호
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• pp.485-497
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• 2012

Objectives : The aim of this study was to systematically investigate herbal-drug-associated adverse drug reactions (herbal ADRs) reports submitted by a single oriental hospital and to analyze the general characteristics, causative agents, clinical manifestations, severity and types of herbal medicines which caused herbal ADRs. Methods : This study proceeded with IRB approval. The data on herbal ADR were collected prospectively from January 2008 to February 2012 by EMR of Dongguk University Ilsan Oriental Hospital. The World Health Organization (WHO)-Uppsala Monitoring Center (UMC) criteria was used to determinate causality for each herbal ADR. WHO-Adverse Reaction Terminology (WHO-ART) System Organ Class (SOC) code and WHO severity category were also used in this study. Results : A total of twenty eight cases were reported. Twenty two cases were assessed to have over possible relations with herbal medication. The gender ratio of these cases were 64.6 percent female and 36.4 percent male, demonstrating no statistical significance. Patients aged over 60 were 59.1%. Gastro-intestinal system was reported to be the most frequently affected organ (38.8%), and followed by psychiatric system (22.4%), and integumentary system (22.4%). The most common clinical symptom was headache (12.2%), followed by diarrhea (10.2%), and pruritus (10.2%). The severity of most cases was assessed to be mild (89.8%). The percentage of moderate ones was 10.2%, and there were no severe cases. Conclusions : Progressive study and further analysis on herbal ADRs are warranted for safety in the clinical use of herbal medicines.

• 생물정신의학
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• 제6권2호
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• pp.253-258
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• 1999

The fluoxetine is one of the most frequently prescribed drugs for the treatment of depression and obsessive-compulsive disorder(OCD). This has been known as one of the most safest medication. But since the advent of this drug, there have been several reports of side effects-the mania and suicidal ideation-encountered during coadministration of fluoxetine with or without other psychotropic drugs. We experienced a case of 20 years old male OCD patient who developed into abrupt manic state and also was preoccupied with intense suicidal ideation following fluoxetine use. He was a only child in his family and his father had a history of alcoholism about 15years ago. Our patient's obsessive-compulsive symptoms have been occured since puberty. His OCD symptoms and anxiety were aggravated since joining the army. Beside these facts, we could not find any other psychiatric history such as depressive disoder and bipolar disorder. We used the fluoxetine starting dosage of 20mg and increased to 40mg at second week. About 3 weeks after the treatment, he developed sudden manic symptom and more aggravated suicidal ideation without any OCD symptoms. He felt vitalized and energetic without having enough sleep and food. These symptoms were ceased over two weeks by stopping medication. Up to this point, the reason why fluoxetine induces mania and suicidal preoccupation is unclear. But somehow the fluoxetine has effects on serotonin receptor and serotonin-dopamine regulations, thus we could make an assumption that fluoxetine can induce mania, extrapyramidal symptoms(EPS) and suicidal ideation in some part of the serotonin unbalanced patients. We think this would be the first report to remark on fluoxetine's suicidal and manic side effects in Korea. So here we present the case with the summary of reviewed articles.