• Journal of Nutrition and Health
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• 제41권8호
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• pp.754-766
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• 2008

본 연구는 대구 경북지역의 유방암 환자와 대조군을 대상으로 열량 및 영양소 섭취수준에 따른 유방암 발생의 상대 위험도를 분석하였다. 조사 대상자는 경북대학교 병원에서 유방암 진단을 처음 받고 입원한 103명의 유방암 환자와 유방암과 관련된 질환 및 전신 질환이 없으면서 연령(5세 내의 차이) 및 폐경 상태가 동일한 사람들을 대상으로 빈도 짝짓기를 통하여 선정한 159명의 지역사회 대조군이었다. 이들의 반정량적 식품섭취 빈도조사 결과를 분석하여 영양 섭취량을 산출하였고, 일반 특성에 대한 분석 결과에서 환자군과 대조군간 유의한 차이를 보인 요인들을 혼란변수로 통제한 후 열량 및 영양섭취 수준에 따른 상대 위험도를 분석하였다. 전체적으로 높은 BMI와 열량과 당질의 높은 섭취 수준은 유방암 발생의 상대적 위험을 유의하게 높이는 것으로 나타났고, 총 지방, 식이섬유, 포화지방산, 단일불포화지방산, 다불포화지방산, n-3 지방산, n-6 지방산, 비타민 E, 칼슘은 섭취수준이 높을수록 위험도가 유의하게 낮아지는 것으로 나타났다. 폐경 전 여성에서는 당질의 섭취 수준이 높을 때 유방암 위험이 유의하게 높고, 총지방, 식이섬유, 포화지방산, 단일불포화지방산, 다불포화지방산, n-6 지방산, 비타민 E, 엽산, 칼슘, 인, 칼륨의 섭취 수준이 높을 때 위험도가 유의하게 낮은 것으로 나타났다. 폐경 후 여성에서는 총지방, 콜레스테롤, 다불포화지방산, n-6 지방산의 섭취 수준이 높을 때 유방암 위험도가 유의하게 낮은 것으로 나타났다. 특히 지방의 경우 식물성 급원의 섭취 수준이 높을 때 유방암의 위험이 유의하게 감소되는 것으로 나타났다. 이상의 결과에서 대구 경북지역에서 유방암 발생 위험을 높일 가능성이 있는 영양섭취상태는 열량과 당질의 높은 섭취이며, 한편 유방암의 위험을 낮출 가능성이 있는 영양섭취 상태는 높은 지방의 섭취로 나타났다. 특히 지방의 경우 식물성 급원의 섭취가 높을 때 위험이 낮아지는 것으로 나타났다. 이는 지방 섭취량과 유방암 위험도 사이에 정의 상관성을 보고한 일부 국외의 연구 결과와는 상반되는 결과이며 그 원인으로는 한국인의 경우 식물성 지방 섭취의 비율이 서구인에 비해 상대적으로 높기 때문인 것으로 추정된다. 유방암의 위험을 낮출 가능성이 있는 미량 영양소로는 비타민 중에는 E와 엽산, 무기질로서는 칼슘, 인 그리고 칼륨으로 나타났다. 본 연구결과의 제한점으로서 조사 사례수가 적다는점을 들 수 있으므로 선행연구들의 결과와 상반된 결과를 보인 지방섭취와 유방암 위험과의 관련성에 대해서는 향후보다 많은 사례를 대상으로 한 조사 연구를 통해 재확인할 필요가 있다고 보며, 본 연구의 결과는 지역민의 유방암 예방을 위한 영양교육 자료의 일부로서 활용될 수 있다고 본다.

• 정신신체의학
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• 제30권1호
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• pp.30-37
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• 2022

연구목적 본 연구는 정신건강 고위험군 대학생을 위한 인지행동치료 기반 개입 프로그램의 개발 및 정신건강 요인들에 대한 치료 효과 확인을 목표로 하였다. 방 법 본 프로그램은 대학생 특정 개입으로서 우울 등의 문제 증상을 감소시키고 회복탄력성 및 긍정정서를 증진시키기 위해 개발되었다. 총 26명의 고위험군 대학생을 대상으로 총 8주동안의 집단 프로그램을 진행하여, 우울, 회복탄력성, 삶의 만족도, 긍정 및 부정적 정서의 사전, 사후 변화를 측정하여 비교하였다. 결 과 본 프로그램의 주요 목표 증상인 우울 점수는 개입 전에 비해 개입 후 유의미하게 감소하였다(t=3.51, p=0.002). 또한, 대학생들의 회복탄력성(t=-3.65, p=0.001)과 삶의 만족도(t=-3.00, p=0.006)와 같은 보호 요인 또한 유의미하게 향상되었다. 한편, 부적 정서는 개입 전후 유의미한 차이가 관찰되지 않았으며(t=-0.94, p=0.356), 긍정 정서는 개입 후 감소하였다(t=2.28, p=0.031). 결 론 본 연구는 집단 프로그램 시행 후 참가자들의 우울 증상이 감소하고, 회복탄력성 및 삶의 만족도가 증가함을 확인하였다. 이는 본 프로그램이 대학생 정신건강 고위험군의 문제 증상 및 보호 요인에 효과적으로 개입할 수 있음을 시사한다.

• Journal of Nutrition and Health
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• 제35권3호
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• pp.380-393
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• 2002

The purpose of this study was to investigate the lift-style and eating behavior of stomach cancer patients in the Daegu and Kyungpook area, and to collect basic data for nutrition education designed to prevent stomach cancer in this community. The subjects of the study were 102 patients who were recently diagnosed as having stomach cancer at the Kyungpook National University Hospital. The control subjects were 105 persons who did not have any gastrointestinal disease, and included patients from the Department of Orthopedic Surgery and healthy volunteers. The survey, which covered the personal characteristics and eating behavior of the subjects, was conducted by individual interviews using questionnaires. It was found that the stomach cancer patients (case group) had experienced a significantly higher level of stress in their daily lives than the control group. A significantly higher proportion of the case group subjects recognized their personality as pessimistic, and had family histories of cancer, compared with the control group subjects. The cancer patients had higher preferences for salty and hot tasting foods, and tended to ingest meals faster without enough chewing, compared with the control subjects. The level of nutritional knowledge of the case group was lower than the control group, and there was a positive correlation between subjects' nutritional knowledge scores and nutritional attitude scores. Subjects' estimates of their food intake frequencies during the decade before the cancer was diagnosed revealed that the case group consumed significantly higher amounts of pickled fish, soybean paste soup and stew, cooked vegetables, beef and pork, charcoal broiled meat and alcohol, while consuming significantly lower amounts of green tea than the control group. In summary, the results of the study suggest that the stress of daily life, a family history of cancer, and a pessimistic personality might be the risk factors for the development of stomach cancer. Dietary factors which were suspected as risk factors for stomach cancer in the present study included strong preferences to salty and hot lasting foods, poor eating habits, and frequent consumption of pickled fish, soybean paste soup, cooked vegetables, beef and pork, charcoal broiled meat and alcohol. A high consumption of green tea seemed to be a protective factor against stomach cancer. The results of the study appear to provide useful data for nutritional education focussed on the prevention on stomach rancor in local residents.

• 농촌의학ㆍ지역보건
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• 제38권2호
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• pp.71-84
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• 2013

지역사회 노인들의 자살생각에 영향을 주는 요인을 확인하기 위해, 경주시에 거주하는 재가노인 중 지역사회 내 노인정을 주기적으로 방문하는 157명의 노인들을 대상으로, 설문지를 이용하여 통증, 일상생활능력, 가족지지, 우울, 그리고 자살생각을 조사하였다. 얻어진 자료는 SPSS/PC(version 18.0)의 t-test 혹은 ANOVA를 이용하여 집단에 따른 자살생각의 차이를 비교하였으며, Pearson 상관분석을 통해 각 변수 간 관련성을 측정하였고, 최종적으로 자살생각에 영향하는 요인을 구별하기 위해 위계적 회귀분석을 실시한 결과는 다음과 같다.; 무교노인들의 자살생각이 유의하게 높았으며, 경제 상태를 낮게 지각하는 노인의 자살생각이 타 경우에 비해 유의하게 높았다. 스스로의 건강상태를 나쁘다고 인식하는 경우 자살생각이 유의하게 높았으며, 통증이 평균 이상인 집단이 그렇지 않은 경우에 비해 자살생각이 유의하게 높았으며, 우울이 평균 이상인 집단이 역시 자살생각이 유의하게 높았다. 상관관계를 측정한 결과, 자살 생각과 음의 관련성을 보인 요인들은 노인이 소속된 사회 모임의 수, 지각된 건강 상태, 일상생활수행능력, 그리고 가족지지 등이었다. 반면에 신체적 질병의 수, 통증, 그리고 우울 등은 자살 생각과 양의 관련성을 보였다. 지역사회 노인들의 자살생각에 영향을 미치는 요인을 확인한 결과, 사회인구학적 변수만을 투입한 경우 남성 노인일수록 그리고 사회 모임의 수가 적을수록 자살생각이 증가하는 것으로 나타났다. 그러나 최종 모형에서는 우울만이 자살생각에 유의하게 영향을 주는 변수로 채택되었으며, 그 설명력은 38.4%로 측정되었다. 이상의 결과를 바탕으로, 종교가 없는 노인들, 건강상태가 나쁜 노인들, 참여하고 있는 사회 모임의 수가 적은 노인들, 경제적으로 취약한 노인들, 신체적 질병이 다수인 노인, 일상생활수행능력이 저하된 경우, 그리고 가족의 지지가 부족한 소외 노인들, 만성적인 통증을 호소하는 노인, 우울감이 있는 노인들을 대상으로 우울이나 자살 생각을 정기적으로 측정하는 것이 필요하다고 사료된다. 특히, 우울은 자살 생각을 설명할 수 있는 유일한 설명 요소로 확인이 되었기에, 자살 예방의 관점에서 노인의 우울은 반드시 관리되어야 할 것이다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.2007-2017
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• 2016

Background: Modifying lifestyle factors such as diet and exercise can reduce the risk of cancer. Psychological stress (PS) might be indirectly associated with cancer because it alters lifestyle factors. However, the relationship among these variables has not been fully investigated. Thus, we examined interactions between self-reported PS (SRPS) and habitual exercise on diet. Materials and Methods: In all, 5,587 men and 2,718 women were divided into "exerciser" and :non-exerciser" groips, based on whether they exercised reguarly, and classified into three SRPS levels: low, moderate and high. Diet was estimated using a validated food frequency questionnaire. Using a general linear model, food and nutrient consumption was estimated for each SRPS level in the 2 exercise groups, and the interactions between SRPS levels and exercise were calculated. Results: In women, the intake of pork and beef, low fat milk and yogurt, natto (fermented soybean), carrots and squash, other root vegetables, mushrooms, seaweeds, and wine along with the nutrients vegetable protein, soluble, insoluble and total dietary fiber, daidzein, genistein, carotene, retinol equivalents, vitamin B2, pantothenic acid, potassium, calcium, magnesium, phosphorus and iron demonstrated significant interaction with SRPS and habitual exercise (p for interaction <0.05). In men, raw and green leafy vegetable and fruit and vegetable juice significantly interacted with SRPS and habitual exercise (p for interaction <0.05). Conclusions: We suggest that certain foods and nutrients, which are thought to have a protective effect against cancer, interact with SRPS and habitual exercise, especially in women. This information is valuable for understanding and improving interventions for cancer prevention.

• Journal of Hospice and Palliative Care
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• 제25권2호
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• pp.55-65
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• 2022

Caring for patients with cancer is highly stimulating and rewarding, attracting health professionals to the field who enjoy the challenge of managing a complex illness. Health professionals often form close bonds with their patients as they confront ongoing disease or treatment impacts, which may be associated with multiple losses involving function and/or eventual loss of life. Ongoing exposure to patient loss, along with a challenging work setting, may pose significant stress and impact health professionals' well-being. The prevalence rates of burnout and compassion fatigue (CF) are significant, yet health professionals have little knowledge on these topics. A 6-week continuing education program consisting of weekly small-group video-conferencing sessions, case-based learning, and an online community of practice was delivered to health care providers providing oncology care. Program content included personal, organization and team-related risk and protective factors associated with CF, grief models, and strategies to mitigate against CF. Content analysis was completed as part of the program evaluation. In total, 189 participants (93% nurses) completed the program, which was associated with significant improvements in confidence and knowledge of CF and strategies to support self and team resilience. Qualitative themes and vignettes from experiences with the program are presented. Key themes included knowledge gaps, a lack of support related to CF and strategies to support resilience, organization-and team-based factors that can inhibit expression about the impacts of clinical work, the health professional as a "person" in caregiving, and the role of personal variables, self-skill practices, and recommendations for education and support for self and teams.

• 재무관리연구
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• 제1권1호
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• pp.119-131
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• 1985

Although Korea is short of capital technology, and natural resources, she has achieved an outstanding progress by the export-drive policies by Korean government and the creative endeavor of Korean firms. As a result of that, Korean economy and enterprises are in the same file of newly industrialized countries and Korea is ready for an economic take-off as a developed country. But in the early 1980s, each country strengthens protective trade theory and resources nationalism, and this has a great influence on the field of international trade environment. In spite of that, to continue the same high development as that of the past. Korea must try to secure and find export markets, solve trade barriers, make sure of the long-term security of resources, develop technology, and strengthen economic cooperations. To satisfy these desires by 2000s, we must try to make Korean enterprises have the global competitive power and them grow strongly among world wide firm through capital and technology accumulated during the passed years, and to do so, there must be a foreign production and marketing management, too, this can be achieved only through foreign overseas direct investment. This investment has various forms, to say, verifical integrated, horizontal integrated. conglomerate integrated forms, and the amount of investment in each country from 18 century to today reaches 500 billion dollars. This investment is done by strategic, behavioral economic, and financial motives. So I am going to approach the fields of like these; in spite of the differences among political, economical, caltural, and social systems, and many risk compared with domestic enterprises, why do Korean firms witsh to transfer the productive facilities to overseas countries and run them there? What is the comparative advantage of foreign direct investment compared with domestic investment ?. why is the factor of comparative advantage transferred through foreign direct investment?, what is the motive of foreign overseas direct investment?, and last the ownership-specific factors and the theory of internalization, and the location specific factors were analysed chiefly. But in consideration of the given condition in Korea, Korean overseas direct investment must be propelled rationally on the basis of the above mentioned theory.

• Journal of Chest Surgery
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• 제18권4호
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• pp.718-731
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• 1985

Renal dysfunction is a common complication of open-heart surgery: a form of controlled hemorrhagic shock, and successful perioperative management of renal dysfunction depends on recognition of the risk factors and optimal management of factors influencing renal function, including cardiopulmonary bypass, and early detection of renal failure. Changes in renal functional parameters including Ccr, Cosm, CH2O, FENa, and RFI were observed prospectively in forty five patients operated on at Dept. of Thoracic and Cardiovascular Surgery, S.N.U.H., from April to June, 1985. They were 23 males and 22 females with 35 acquired and 10 congenital heart diseases and the mean age and body surface area of them were 38.010.3 years [22-63] and 1.5518 M2[1.151.92] respectively. Followings are the conclusion. 1. The Ccr, representative of renal function, is significantly improved from 90.231.3 ml/min/M2 preoperatively to 101.536.4 ml/min/M2 postoperative and day [P<0.05], and all patients were classified as postoperative renal functional class I of Abel, which representing adequate renal protection during our cardiopulmonary bypass. 2. The Cosm is significantly elevated at immediate postperfusion time and remained high at postoperative one day representing osmotic diuresis at that time, but CH2O shows no significant changes at immediate postperfusion period and is decreased significantly at postoperative one day, representing recovery of renal concentrating ability at that time with decreasing urine flow. 3. The absolute value and changing tendency in FENa and RFI during perioperative period shows no diagnostic reliability on these parameters, but those of CH2O appear to reveal future renal function more accurately than Ccr 4. The depth of hypothermia may be protective upon renal function against the ill effects of prolonged nonpulsatile cardiopulmonary bypass. 5. The depth of the hypothermia, pump time of more than 150 minutes, poor cardiac function, and intraoperative events such as embolism appear to be related with immediate postperfusion renal function. 6. Hemoglobinuria and hemolysis, poor preoperative renal function, history of cardiac surgery, and massive transfusion associated with bleeding appear not to be related with renal dysfunction.

• Asian Pacific Journal of Cancer Prevention
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• 제14권3호
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• pp.1585-1592
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• 2013

Functional food for prevention of chronic diseases is one of this century's key global challenges. Cancer is not only the first or second leading cause of death in China and other countries across the world, but also has diet as one of the most important modifiable risk factors. Major dietary factors now known to promote cancer development are polished grain foods and low intake of fresh vegetables, with general importance for an unhealthy lifestyle and obesity. The strategies of cancer prevention in human being are increased consumption of functional foods like whole grains (brown rice, barley, and buckwheat) and by-products, as well some vegetables (bitter melon, garlic, onions, broccoli, and cabbage) and mushrooms (boletes and Tricholoma matsutake). In addition some beverages (green tea and coffee) may be protective. Southwest China (especially Yunnan Province) is a geographical area where functional crop production is closely related to the origins of human evolution with implications for anticancer influence.

• Nutrition Research and Practice
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• 제10권1호
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• pp.67-73
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• 2016

BACKGROUND/OBJECTIVES: This study was aimed at examining the association between dietary flavanones intake and lipid profiles according to the presence of metabolic syndrome (MetS) in Korean women with type 2 diabetes mellitus (T2DM). SUBJECTS/METHODS: A cross-sectional analysis was performed among 502 female T2DM patients (non-MetS group; n = 129, MetS group; n = 373) who were recruited from the Huh's Diabetes Clinic in Seoul, Korea between 2005 and 2011. The dietary intake was assessed by a validated semi-quantitative food frequency questionnaire (FFQ) and the data was analyzed using the Computer Aided Nutritional Analysis program (CAN-Pro) version 4.0 software. The intake of flavanones was estimated on the basis of the flavonoid database. RESULTS: In the multiple linear regression analysis after adjustment for confounding factors, daily flavanones intake was negatively associated with CVD risk factors such as total cholesterol, LDL-cholesterol, and apoB and apoB/apoA1 ratio only in the MetS group but not in the non-MetS group. Multiple logistic regression analysis revealed that the odds ratio for a higher apoB/apoA1 ratio above the median (${\geq}0.74$) was significantly low in the $4^{th}$ quartile compared to that in the $1^{st}$ quartile of dietary flavanones intake [OR: 0.477, 95% CI: 0.255-0.894, P for trend = 0.0377] in the MetS group. CONCLUSIONS: Dietary flavanones intake was inversely associated with the apoB/apoA1 ratio, suggesting a potential protective effect of flavanones against CVD in T2DM women with MetS.