• Title/Summary/Keyword: prospective studies

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Prospective Study on the Survival of HCC Patients Treated with Transcatheter Arterial Lipiodol Chemoembolization

  • Mao, Ying-Min;Luo, Zu-Yan;Li, Bo;Hu, Ting-Yang
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.3
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    • pp.1039-1042
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    • 2012
  • Aim: Tanscatheter arterial embolization irrespective of with or without an anticancer agent and lipiodol has been controversial with regard to survival benefit. Therefore, we conducted a prospective study to analyze the effect of transcatheter arterial lipiodol chemoembolization (TACE) on the survival of HCC. Methods: A prospective study was conducted, and a total of 326 patients with primary liver cancer who were newly diagnosed were collected from January 2004 to January 2005 in Zhejiang Provincial People's Hospital of China. A univariate Cox's regression analysis was used to assess the survival of the HCC cases receiving TACE. Results: The duration of follow-up for the HCC patients treated with TACE ranged from 3 months to 60 months. For the overall patients, survival rate at 5 years was 42%. Both HBV Ag and HCV Ab positive patients showed significantly low survival rate at 5 years. The multivariate analysis revealed The IV TNM stage was related to an heavy increased risk of death of HCC patients, and Child C grade group showed a significant moderate increased risk. Conclusion: Our study showed TACE is associated with a better prognosis of HCC patients, and the HBV infection, TNM stage, Child-Pugh grade and number of TACE may influence the survival probability. Further TACE studies should be assess the quality of life of HCC patients, so as to provide more information for treatment of HCC.

Intolerance of Uncertainty Scale: Construct validity of Prospective and Inhibitory factor structure (불확실성에 대한 인내력 부족 척도: 전향적·억제적 요인의 구인 타당도 검증)

  • Choi, Hyo Sun;Kim, Eun-Kyung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.9
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    • pp.338-344
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    • 2020
  • Intolerance of Uncertainty is associated with numerous psychopathologies, including generalized anxiety disorders. However, several studies differ in the factor structures applicable for the Intolerance of Uncertainty Scale (IUS), and there exists a debate regarding the factorial and construct validity. Thus, in the current study, the IUS was newly translated to explore and verify the structures and factors relative to the cultural background of Korea. The study involved an exploratory factor analysis of randomly extracted data from 260 of 533 adults selected. Results determined that a prospective factor of 3 items and inhibitory factor of 5 items was appropriate. In addition, a confirmatory factor analysis and correlation analysis of the remaining 273 data revealed that a structural model comprising of the 8-items two factors model was well suited (x2=37.699, TLI=0.951, CFI=0.969, RMSEA=0.063, SRMR=0.039), and showed significant static correlation with worry, depression, and state-trait anxiety.

A Prospective Analysis of Dynamic Loss of Breast Projection in Tissue Expander-Implant Reconstruction

  • Mioton, Lauren M.;Jordan, Sumanas W.;Kim, John Y.S.
    • Archives of Plastic Surgery
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    • v.42 no.3
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    • pp.309-315
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    • 2015
  • Background Breast projection is a critical element of breast reconstruction aesthetics, but little has been published regarding breast projection as the firm expander is changed to a softer implant. Quantitative data representing this loss in projection may enhance patient education and improve our management of patient expectations. Methods Female patients who were undergoing immediate tissue-expander breast reconstruction with the senior author were enrolled in this prospective study. Three-dimensional camera software was used for all patient photographs and data analysis. Projection was calculated as the distance between the chest wall and the point of maximal projection of the breast form. Values were calculated for final tissue expander expansion and at varying intervals 3, 6, and 12 months after implant placement. Results Fourteen breasts from 12 patients were included in the final analysis. Twelve of the 14 breasts had a loss of projection at three months following the implant placement or beyond. The percentage of projection lost in these 12 breasts ranged from 6.30% to 43.4%, with an average loss of projection of 21.05%. Conclusions This study is the first prospective quantitative analysis of temporal changes in breast projection after expander-implant reconstruction. By prospectively capturing projection data with three-dimensional photographic software, we reveal a loss of projection in this population by three months post-implant exchange. These findings will not only aid in managing patient expectations, but our methodology provides a foundation for future objective studies of the breast form.

Case Study of Mathematical Pedagogy for Prospective Elementary Teachers in the US (미국의 초등 예비교사를 위한 수학 교수법에 관한 사례 연구)

  • Pang, Jeong-Suk
    • Journal of Elementary Mathematics Education in Korea
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    • v.15 no.3
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    • pp.487-507
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    • 2011
  • Despite the recent increased attention to mathematics teacher education there have been lack of empirical studies on how to teach teachers. A study of mathematics instruction for prospective teachers can be conducted either by a teacher educator's critical reflection on her teaching or by observation of others' teaching practices. This paper was from the author's observation of a mathematics instruction course for future elementary teachers at the University of California at Irvine. As such this paper described in detail how the course was implemented throughout the quarter and drew implications for a teacher preparation program in Korea. As the course had a specific purpose of promoting future teachers' expertise in mathematics instruction and employed various strategies that were different from a typical university course, this paper is expected to provide teacher educators with the insight of an alternative teaching style and to provoke discussion of how to connect theory to practice for effective teacher education.

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Volunteering, Hypertension Risks, and Related Phenomena: A Prospective Cohort Study (자원봉사활동과 고혈압 및 관련 현상과의 전향적 연구)

  • Lee, Hyunkee
    • 한국노년학
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    • v.41 no.3
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    • pp.397-420
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    • 2021
  • The paper tried to determine relationships between volunteering and hypertension risks, symptom betterment, activity difficulty occurrences, and medicine treatment among middle-aged and older adults, with a prospective cohort study. Multilevel mixed-effects generalized linear models were used for the analysis of longitudinal panel data collected over 10 years from 2008 to 2018, using 5,867 cohort samples. The results showed that those who volunteered at least 200 hours per year were 3.4 times more lower than not-volunteering in risks of hypertension, those who volunteered yearly 50~99 hours were a lot more improved than not-volunteering in the symptom betterment, those who volunteered yearly at least 200 hours were 7.7 times lower than not-volunteering in activity difficulty occurrences, and those who volunteered yearly 50~99 hours were 2.5 times lower than not-volunteering in the occurrences of medicine treatment. These indicate that volunteering among middle-aged and older adults may have health benefits against incident hypertension. Finally the thesis discusses the study limitations, future directions of studies, and the practices implications.

Trends and Prospective of Environmental Health Research through SWOT Analysis (SWOT 분석을 통한 환경보건 연구의 동향과 전망 고찰)

  • Shin, Jihun;Ra, Jin-Sung;Kim, Ki-Tae;Lee, Jongdae;Yang, Wonho
    • Journal of Environmental Health Sciences
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    • v.48 no.5
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    • pp.255-265
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    • 2022
  • Background: Research in environmental health (EH) is of crucial strategic importance for contemporary society. It is becoming even more critical in light of the increasingly rapid pace of environmental changes, opportunities, and threats. Objectives: This study aimed to identify trends and the prospective of environmental health research using SWOT analysis. Methods: The trends in environmental health research were reviewed in previous studies and reports. Reviewed manuscripts were searched for using the keywords of 'environmental health' and 'environmental hygiene' in the KCI (Korean Journal of Citation Index), KISS (Korean Academic Information), PubMed, and Google Scholar. Results: It is essential to center the EH research agenda around key priorities focusing on technological innovation, job creation, and the increasingly prominent role of the private sector. Given the rapidly evolving global sustainability agenda, greater clarity on the ever-increasing sources of complexity and growing expectations of the public might be needed. This requires the identification of criteria to identify EH research priorities with the ultimate goal of maximizing societal benefit. Public health relevance, such as extent and severity of health impact, level of exposure, and inequalities of effects, could be included. Conclusions: Considering the recent interest in and importance of environmental health, a comprehensive approach to environmental health research should be required through the application of the latest science and technology, citizen participation, and environmental health surveillance systems.

Persistent headache and chronic daily headache after COVID-19: a prospective cohort study

  • Larissa Clementino Leite Sa Carvalho;Priscila Aparecida da Silva;Pedro Augusto Sampaio Rocha-Filho
    • The Korean Journal of Pain
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    • v.37 no.3
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    • pp.247-255
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    • 2024
  • Background: Little is known about the frequency and impact of the persistent headache and about the incidence of chronic daily headache (CDH) after coronavirus disease 2019 (COVID-19). The aim of this prospective cohort study was to assess the incidence, risk factors, characteristics, and impact of CDH in patients with COVID-19. Methods: In the first stage, 288 patients were interviewed by telephone after the acute phase of COVID-19. Subsequently, 199 patients who presented headache were reinterviewed at least one year after COVID-19. Headaches that persisted beyond the acute phase of COVID-19 for three or more months and presented frequency ≥ 45 days over the first three months were considered to be CDH. Results: One hundred and twenty-three patients were included, 56% were females; median age: 50 years (25th and 75th percentile: 41;58). The headache persisted beyond the acute phase of COVID-19 in 52%, and 20.3% had CDH (95% confidence interval: 13.6-28.2). Individuals who previously had headaches and who had headaches of greater intensity during the acute phase were at higher risk of developing CDH. The group with CDH included more females, greater impact of headache, more persistence of headache beyond the 120th day of COVID-19 and less throbbing headache than did the other individuals whose headache persisted. Conclusions: Patients who had COVID-19 had a high incidence of CDH. Previous headache and greater intensity of headache were associated with higher risk of CDH.

Risk Stratification in Cancer Patients with Acute Upper GastrointestinalBleeding: Comparison of Glasgow-Blatchford, Rockall and AIMS65, and Development of a New Scoring System

  • Matheus Cavalcante Franco;Sunguk Jang;Bruno da Costa Martins;Tyler Stevens;Vipul Jairath;Rocio Lopez;John J. Vargo;Alan Barkun;Fauze Maluf-Filho
    • Clinical Endoscopy
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    • v.55 no.2
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    • pp.240-247
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    • 2022
  • Background/Aims: Few studies have measured the accuracy of prognostic scores for upper gastrointestinal bleeding (UGIB) among cancer patients. Thereby, we compared the prognostic scores for predicting major outcomes in cancer patients with UGIB. Secondarily, we developed a new model to detect patients who might require hemostatic care. Methods: A prospective research was performed in a tertiary hospital by enrolling cancer patients admitted with UGIB. Clinical and endoscopic findings were obtained through a prospective database. Multiple logistic regression analysis was performed to gauge the power of each score. Results: From April 2015 to May 2016, 243 patients met the inclusion criteria. The AIMS65 (area under the curve [AUC] 0.85) best predicted intensive care unit admission, while the Glasgow-Blatchford score best predicted blood transfusion (AUC 0.82) and the low-risk group (AUC 0.92). All scores failed to predict hemostatic therapy and rebleeding. The new score was superior (AUC 0.74) in predicting hemostatic therapy. The AIMS65 (AUC 0.84) best predicted in-hospital mortality. Conclusions: The scoring systems for prognostication were validated in the group of cancer patients with UGIB. A new score was developed to predict hemostatic therapy. Following this result, future prospective research should be performed to validate the new score.

Importance of Social Support in Cancer Patients

  • Usta, Yasemin Yildirim
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.3569-3572
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    • 2012
  • Social support is regarded as a complex construct which has long been suggested to have direct and buffering effects on patients' wellbeing and emotional adjustment to cancer. Cross-sectional and prospective studies show a positive association between perceived social support and psychological adjustment following cancer treatment. Research findings suggest that the evidence for the relationship between social support and cancer progression is sufficiently strong. This report points out the importance of social support in cancer and provides recommendations for health care professionals.

Photometric Observations of Eccentric Accretion in Algol-type Binary Stars

  • Reed, Phillip A.
    • Journal of Astronomy and Space Sciences
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    • v.29 no.2
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    • pp.141-143
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    • 2012
  • Some Algol-type interacting binary stars exhibit strange photometric variations that can be phase-dependent and/or secular. This paper discusses the possibility of explaining these observed variations as resulting from an accretion structure eclipsing one or both of the stars. Some previous studies are reviewed and suggestions for future work are made, including the prospective of incorporating data from the Kepler Observatory.