• 제목/요약/키워드: prospective studies

검색결과 859건 처리시간 0.027초

세계화시대와 가정학 연구 (A Prospective Study : Human Ecology-Based Researches in Korea Facing Global Promotion)

  • 박영숙;최혜선;윤인경;이승신;이주리
    • 대한가정학회지
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    • 제42권2호
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    • pp.47-68
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    • 2004
  • Human Ecology researches studying human life patterns in Korea are on the same tracts of recent global promotion in Korea as that of other academic studies. In this changing academic atmosphere, Human Ecology-based researches are in demands of suitable research topics and methods. This study was done to investigate the present research situations of Human Ecology-based subdivisional fields, including food and nutrition, clothing and textiles, child studies, family studies, home management, housing studies, consumer sciences and home economics education, by an increasing need in the society of KHEA (Korean Home Economics Association). The study focused on understanding the trends of research topics and methods shown in the papers published in major academic periodicals in Korea as well as world-class (SCI, SSCI) journals in order to predict the future for Ecology-based studies in Korea. The data were collected from all periodicals from January, 2000 to August, 2003, listed in the Korean Research Foundation and from world-class journals comparable to the former. Twenty-six periodicals were chosen for analysis, including papers with authors of ecology-based, field faculty at colleges or universities. There were some differences between the Korean and world-class research topics and methods. In order to narrow the gap between the two, we suggested that serious consideration be given to the research's application-ability toward human beings, which would be the home-ecology study's identity. The same criteria in these fields as used in other natural science fields are not suitable for supporting and evaluating research proposals and outputs, and recent global academic promotions may not be desirable in some respects. However, they do present an opportunity to expose Korean researcher's to world-class scientific societies and upgrade their studies. These efforts should stimulate the field of Human-Ecology studies and enhance the recognitions of these fields among future students.

대한외상학회지에 게재된 문헌들의 추세: 계량서지학과 인용을 이용한 분석 (Trends in Article Published in the Journal of Trauma and Injury: Bibliometric and Citation Analysis)

  • 예진 허치슨;차현민;오재훈;강형구;임태호;이윤재;강보승;김창선;최혁중
    • Journal of Trauma and Injury
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    • 제28권3호
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    • pp.182-189
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    • 2015
  • Purpose: We performed a quantitative and qualitative analysis in the Journal of the Korean Society of Traumatology (JKST) by Bibliometrics to know the trends of articles. Methods: We reviewed articles in the JKST retrospectively through 1988 to 2014. Articles were classified into original articles, case reports, review articles, and also it is further classified as topics and the information related to the Department of Medicine of corresponding author. Original article was classified prospective and retrospective studies. Results: 753 studies and average of 27.9 studies per year were posted on JKST. 576 original articles (76.5%) were posted. Retrospective studies around 449 studies (78%) were posted and there were about 35 descript studies and 541 analytic studies. The most common themes were related to abdominal trauma, 144 pieces, 95 pieces following damage to the chest and the 84 pieces of special order of trauma. Emergency department had the highest case whereas general surgery came to the second place. Conclusion: Recently, there has been reduced proportion of original article in JKST. It was not possible to evaluate the Korea Citation index journals due to the fact that it does not correspond to listed register Journal of National Foundation of Korea. There will be the need for the effort to improve the maintenance of the posted article number, as well as the qualitative development of the posted articles.

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Matrix Metalloproteinase-9 as a Prognostic Factor in Gastric Cancer: A Meta-Analysis

  • Zhang, Qiong-Wen;Liu, Lei;Chen, Ru;Wei, Yu-Quan;Li, Ping;Shi, Hua-Shan;Zhao, Yu-Wei
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권6호
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    • pp.2903-2908
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    • 2012
  • Background: Matrix metalloproteinase-9 (MMP-9) is associated with disruption of basement membranes of blood vessels and promotion of metastasis through the lymphatics. However, its prognostic value for survival in patients with gastric cancer remains controversial. Method: We therefore conducted a meta-analysis of the published literature in order to clarify the impact of MMP-9. Clinical studies were selected for further analysis if they provided an independent assessment of MMP-9 in gastric cancer and reported analysis of survival data according to MMP-9 expression. Results: A total of 11 studies, covering 1700 patients, were included for meta-analysis. A summary hazard ratio (HR) of all studies and sub-group hazard ratios were calculated. The combined HR suggested that a positive MMP-9 expression had an impact on overall survival: 1.25 (95% confidence interval 1.11-1.40) in all eligible studies; 1.13 (1.06-1.20) in 8 studies detecting MMP-9 by immunohistochemistry; 1.36 (1.12-1.65) in 7 studies from Asia. Only one study for DFS showed a significant impact on disease free survival (HR 1.73, 95%CI 1.27-2.34). Conclusions: Our findings suggested that MMP-9 protein expression might be a factor for a poor prognosis in patients with gastric cancer. However, the association was rather weak, so that more prospective studies should further explore the prognostic impact of MMP-9 mRNA and correlations between MMP-9 and clinicopathological characteristics.

건강신념모델과 한국인 만성질환자의 환자역할 행위 (Health Belief Model and Sick Role Behavior of Koream Chronic ill Paients)

  • 구미옥;이은옥
    • 대한간호
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    • 제29권3호
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    • pp.49-63
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    • 1990
  • This article reviewed & analyzed 33 studies of the Health Belief Model applied to korean chronic ill patients which were published from 1975 to 1990. The findings of analysis are as follows. The subjects of researchs are patients with various chronic illness including Pulmonary Tb., DM., Hemodialysis & Kindney Transplantation, Hypertension, etc. The type of research is retrospective survey in all studies. The measurement of health' belief in all studies & sick role behavior in most studies have relied on self report. The analysis of the relationship between health belief and sick role behavior was done using correlation coefficient in most studies. To analyze empirical support for the relatiohship between health belief and sick role behavior, Significance ratio was computed. This ratio is value wherein the number of statistically significant findings with relationship in the expected direction for an HBM dimension are divided by total number of studies which reported significance levels for that dimension. Examination of this ratio across the 33 studies reveals susceptibility(30.3%), severity(34.4%), benifit(65.6%), barrier(50%). The following suggestions are based on the above findings and literature review. 1. It is necessary to develop the reliable, valid and standadized instrument for measurement of health beliefs. 2. In the further 'measurement of perceived susceptibility of the chronic ill patients, It is considering that the perceived susceptibility and perceived severity are measured together or the measurement of perceived, susceptibility is eliminated. 3. Relationship between perceived severity and sick role behavior is suggested to be analized using ANOV A, $x^2$ square instead of correlation coefficient. 4. Sick role behaviors should be measured by both self report and objective measurement. 5. Prospective, longitudinal survey should be needed. 6. Other factors influencing sick role behaviors of chronic ill patients should be investigated further.

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Biomarkers associated with periodontitis and peri-implantitis: a systematic review

  • Kalsi, Amardip Singh;Moreno, Federico;Petridis, Haralampos
    • Journal of Periodontal and Implant Science
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    • 제51권1호
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    • pp.3-17
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    • 2021
  • Purpose: The pathology of peri-implantitis is still not fully understood and there have been recent challenges to the consensus on its aetiology and pathology, especially in comparison with periodontitis. The assessment of biomarkers allows a comparison of the pathology of these diseases. The aim of this systematic review was to answer the research question: "Is there a difference in the biomarkers associated with peri-implantitis compared with periodontitis in adult humans?" Methods: Electronic databases were searched and screened, and a manual search was also undertaken. The inclusion criteria were adults with peri-implantitis who had been compared to adults with periodontitis with the outcome of biomarkers assessed via biopsies or crevicular fluid samples in primary or secondary care settings, as recorded in case-control, case series and retrospective, prospective and cross-sectional observational studies. Two reviewers independently screened titles and abstracts and assessed full text articles for eligibility and inclusion. Both reviewers independently extracted data and assessed risk of bias. Differences in biomarker levels were the primary outcome and a narrative review was undertaken due to the heterogeneity of studies. Results: In total, 2,374 articles were identified in the search, of which 111 full-text articles were assessed for eligibility and 13 were included in the qualitative synthesis. Five of the 13 included studies were deemed to be at high risk of bias, with the others having moderate risk. All studies were cross-sectional and performed at university hospitals. Nine of the 13 included studies found significant differences in the levels of biomarkers or their ratios between periimplantitis and periodontitis. Four of the studies found no significant differences. Conclusions: Within the limitations of the included studies, it appears that there may be a difference in biomarker levels and ratios between peri-implantitis and periodontitis, suggesting that these disease processes are somewhat distinct.

The association between dietary sodium intake and obesity in adults by sodium intake assessment methods: a review of systematic reviews and re-meta-analysis

  • Jounghee Lee;Cheongmin Sohn;Oh-Yoen Kim;Young-Min Lee;Mi Ock Yoon;Myoungsook Lee
    • Nutrition Research and Practice
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    • 제17권2호
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    • pp.175-191
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    • 2023
  • BACKGROUND/OBJECTIVES: The scientific evidence of a sodium-obesity association is limited by sodium intake assessments. Our specific aim is to synthesize the association between dietary sodium intake and obesity across the sodium intake assessments as evidenced by systematic reviews in adults. SUBJECTS/METHODS: A systematic search identified systematic reviews comparing the association of dietary sodium intakes with obesity-related outcomes such as body mass index (BMI), body weight, waist circumference, and risk of (abdominal) obesity. We searched PubMed on October 24, 2022. To assess the Risk of Bias in Systematic Reviews (ROBIS), we employed the ROBIS tool. RESULTS: This review included 3 systematic reviews, consisting of 39 unique observational studies (35 cross-sectional studies and 4 longitudinal studies) and 15 randomized controlled trials (RCTs). We found consistently positive associations between dietary sodium intake and obesity-related outcomes in cross-sectional studies. Studies that used 24-h urine collection indicated a greater BMI for those with higher sodium intake (mean difference = 2.27 kg/m2; 95% confidence interval [CI], 1.59-2.51; P < 0.001; I2 = 77%) compared to studies that used spot urine (mean difference = 1.34 kg/m2; 95% CI, 1.13-1.55; P < 0.001; I2 = 95%) and dietary methods (mean difference = 0.85 kg/m2; 95% CI, 0.1-1.51; P < 0.05; I2 = 95%). CONCLUSIONS: Quantitative synthesis of the systematic reviews has shown that cross-sectional associations between dietary sodium intake and obesity outcomes were substantially different across the sodium intake assessments. We need more high-quality prospective cohort studies and RCTs using 24-h urine collection to examine the causal effects of sodium intake on obesity.

Prognostic factors associated with the success rates of posterior orthodontic miniscrew implants: A subgroup meta-analysis

  • Hong, Sung-Bin;Kusnoto, Budi;Kim, Eun-Jeong;BeGole, Ellen A;Hwang, Hyeon-Shik;Lim, Hoi-Jeong
    • 대한치과교정학회지
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    • 제46권2호
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    • pp.111-126
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    • 2016
  • Objective: To systematically review previous studies and to assess, via a subgroup meta-analysis, the combined odds ratio (OR) of prognostic factors affecting the success of miniscrew implants (MIs) inserted into the buccal posterior region. Methods: Three electronic searches that were limited to articles on clinical human studies using MIs that were published in English prior to March 2015 were conducted. The outcome measure was the success of MIs. Patient factors included age, sex, and jaw of insertion (maxilla vs. mandible), while the MI factors included length and diameter. A meta-analysis was performed on 17 individual studies. The quality of each study was assessed for non-randomized studies and quantified using the Newcastle-Ottawa Scale. The meta-analysis outcome was a combined OR. Subgroup and sensitivity analyses based on the study design, study quality, and sample size of miniscrews implanted were performed. Results: Significantly higher success rates were revealed for MIs inserted in the maxilla, for patients ${\geq}20$ years of age, and for long MIs (${\geq}8mm$) and MIs with a large diameter (> 1.4 mm). All subgroups acquired homogeneity, and the combined OR of the prospective studies (OR, 3.67; 95% confidence interval [CI], 2.10-6.44) was significantly higher in the maxilla than that in the retrospective studies (OR, 2.10; 95% CI, 1.60-2.74). Conclusions: When a treatment plan is made, these risk factors, i.e. jaw of insertion, age, MI length, and MI diameter, should be taken into account, while sex is not critical to the success of MIs.

암의 발생과 진행에 있어서 심리적 요인 (Psychological Effects on the Development and Course of Cancer)

  • 전우택
    • 정신신체의학
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    • 제2권1호
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    • pp.10-21
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    • 1994
  • The author reviewed the effect of psychological factors on the development and course of cancer. Cancer is a bilogical disease, but it also has a large number of psychological aspects. There have been no reports that specific personality types had tendency to cause cancer. In some studies, however, type A personality was reported to have relevance to a higher incidence of cancer and a better prognosis. And in other studies, type C personality was reported to have relevance to a higher incidence of cancer. It was reported that people who had strong tendency to control their anger and regarded the rationality and antiemotionality in their behavior as important things were susceptable to cancer. In the course of cancer, the patients who had more positive and aggressive attitude and 'fighting spirit' to their disease tended to have a better prognosis than those who accepted their disease as fate. Some studies showed that feeling of helplessness and loss of control had a negative offset on cancer. It was reported that, in the early stage of cancer, the psychological factors had great influence on the prognosis, but in the middle and late stage, the influence decreased. For the future studies, cancer should not be regarded as a single disease and a single condition. The kinds and stages of cancer should be difined for studies. The scales for psychological evaluation for cancer patients should be sensitive and selected carefully, considering the complexity of the cancer patients mind. The need for prospective studies is emphasized. Finally, as the cured cancer patients have great difficulties in returning to their work and daily life, rehabilitation of cancer patients is also emphasized.

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The Oncological Safety of Nipple-Sparing Mastectomy: A Systematic Review of the Literature with a Pooled Analysis of 12,358 Procedures

  • Headon, Hannah Louise;Kasem, Abdul;Mokbel, Kefah
    • Archives of Plastic Surgery
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    • 제43권4호
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    • pp.328-338
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    • 2016
  • Nipple-sparing mastectomy (NSM) is increasingly popular as a procedure for the treatment of breast cancer and as a prophylactic procedure for those at high risk of developing the disease. However, it remains a controversial option due to questions regarding its oncological safety and concerns regarding locoregional recurrence. This systematic review with a pooled analysis examines the current literature regarding NSM, including locoregional recurrence and complication rates. Systematic electronic searches were conducted using the PubMed database and the Ovid database for studies reporting the indications for NSM and the subsequent outcomes. Studies between January 1970 and January 2015 (inclusive) were analysed if they met the inclusion criteria. Pooled descriptive statistics were performed. Seventy-three studies that met the inclusion criteria were included in the analysis, yielding 12,358 procedures. After a mean follow up of 38 months (range, 7.4-156 months), the overall pooled locoregional recurrence rate was 2.38%, the overall complication rate was 22.3%, and the overall incidence of nipple necrosis, either partial or total, was 5.9%. Significant heterogeneity was found among the published studies and patient selection was affected by tumour characteristics. We concluded that NSM appears to be an oncologically safe option for appropriately selected patients, with low rates of locoregional recurrence. For NSM to be performed, tumours should be peripherally located, smaller than 5 cm in diameter, located more than 2 cm away from the nipple margin, and human epidermal growth factor 2-negative. A separate histopathological examination of the subareolar tissue and exclusion of malignancy at this site is essential for safe oncological practice. Long-term follow-up studies and prospective cohort studies are required in order to determine the best reconstructive methods.

군진의학에서의 침치료 활용을 위한 연구동향 고찰 (A Study on Research for Utilization Acupuncture Treatment in Military Medicine)

  • 최희승;차윤엽
    • 한방재활의학과학회지
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    • 제26권3호
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    • pp.85-95
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    • 2016
  • Objectives Military medicine is the study of research which includes health, sanitation, clinic, and quarantine in military personnel. This study is focused on research the acupuncture treatment of military medicine. Methods The study on acupuncture research for Military Medicine was referred from via KoreaMed, OASIS, The Journal of Korean Military Medical Association, KMbase, KAMJE, NDSL, KISS, KISTI, PubMed, MEDLINE, EMBASE, and The Cochran library. As a result, 18 research papers were found and they were analyzed according to the year of publishment, the titles of journals, the nation of research center, the types of study, the purpose of study, the outcome of measurement, the type of acupuncture, and the assessment of acupuncture effect. And then assessed the risk of bias about RCT, NRCT, prospective cohort studies, and before and after studies. Results The number of the published research papers on acupuncture was increased since 2013. The studies were mainly published in the USA and eight out of 18 were RCT. The purpose of study is mostly for musculoskeletal and psychological disease and medical decision for acupuncture. The type of the acupuncture used is not only traditional acupuncture but also the auricular acupuncture. Even though the research results about the effect of acupuncture were excellent and positive, some of studies had a high risk of bias. Conclusions The studies state about acupuncture treatment as mostly positive and effective, however, further clinical studies are required to obtain objective clinical evidence of acupuncture treatment. Furthermore, future trials would be needed to find out effective acupuncture treatments on military duty.