• Childhood Kidney Diseases
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• v.27 no.2
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• pp.97-104
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• 2023

Purpose: Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers (ARBs) are frequently employed to counteract the detrimental effects of proteinuria on glomerular diseases. However, the effects of ARBs remain poorly examined in pediatric patients with immunoglobulin A (IgA) nephropathy. Herein, we evaluated the efficacy and safety of losartan, an ARB, in pediatric IgA nephropathy with proteinuria. Methods: This prospective, single-arm, multicenter study included children with IgA nephropathy exhibiting proteinuria. Changes in proteinuria, blood pressure, and kidney function were prospectively evaluated before and 4 and 24 weeks after losartan administration. The primary endpoint was the difference in proteinuria between baseline and 24 weeks. Results: In total, 29 patients were enrolled and received losartan treatment. The full analysis set included 28 patients who received losartan at least once and had pre- and post-urinary protein to creatinine ratio measurements (n=28). The per-protocol analysis group included 22 patients who completed all scheduled visits without any serious violations during the study period. In both groups, the mean log (urine protein to creatinine ratio) value decreased significantly at 6 months. After 24 weeks, the urinary protein to creatinine ratio decreased by more than 50% in approximately 40% of the patients. The glomerular filtration rate was not significantly altered during the observation period. Conclusions: Losartan decreased proteinuria without decreasing kidney function in patients with IgA nephropathy over 24 weeks. Losartan could be safely employed to reduce proteinuria in this patient population. ClinicalTrials.gov trial registration (NCT0223277)

• Journal of Industrial Convergence
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• v.22 no.1
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• pp.75-84
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• 2024

This study aims to provide basic data for improved the level of subjective health awareness in the physical and mental aspects of prospective seniors by verifying the effect of self-esteem of pre-elderly on subjective health awareness and the mediating effect of interpersonal skills. For the analysis, data were collected through a survey of 270 prospective seniors aged 55 and over to 64 years old, who participated in the prospective elderly program operated by social welfare institutions in the metropolitan area, from February 16 to March 16, 2023, and SPSS WIN 25.0 and PROCESS MACRO were used. Frequency analysis, descriptive statistics analysis, and correlation analysis were conducted as analysis methods, and the mediating effect of interpersonal ability was verified through structural equation analysis, and the main analysis results are as follows. First, it was found that the self-esteem of the pre-elderly had a positive (+) effect on subjective health perception. Second, interpersonal ability showed a mediating effect in the relationship between self-esteem and subjective health perception of pre-elderly. Based on these results, it is significant in that it presents basic data for a successful and active retirement life in the future old age.

• Journal of Digital Convergence
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• v.22 no.1
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• pp.33-38
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• 2024

In recent years, as more and more middle-aged people who worked at companies are retiring, they are becoming interested in starting their own businesses, and the rate of middle-aged people starting businesses is increasing. The purpose of this study was to analyze the quality and satisfaction of educational services and trust in educational institutions in providing entrepreneurship education to prospective entrepreneurs over the age of 40 who want to start a business, and to analyze the impact of entrepreneurship education on entrepreneurship in the future. Afterwards, the goal is to establish an education strategy to improve the quality of entrepreneurship education. To achieve the purpose of the study, a hypothesis was established and an empirical analysis was conducted on educated prospective entrepreneurs and retirees over 40 years of age. As a result of the analysis, it was confirmed that confidence and reliability ultimately influence the factors that increase satisfaction with entrepreneurship education for middle-aged and older people. Satisfaction was found to play a meaningful role in trust. The research points out that entrepreneurship education institutions should provide education centered on the trainees rather than entrepreneurship education centered on support organizations. Moreover, due to the diversity of education, not only the content and method of education but also the education of employees working in supporting organizations is important.

• Journal of the Korean Society of Marine Environment & Safety
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• v.30 no.4
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• pp.308-316
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• 2024

Maintaining the appropriate number of national seafarers is essential for securing the competitiveness of maritime industry and security in Korea. However, the number of national seafarers in Korea has been decreased continuously recently. The government recognizes the repercussion of this issue and has been attempting to solve it. One of the most significant reasons contributing to the rapid decrease in national seafarers is presumed to be the high initial turnover rate due to the decreased preference for maritime careers among people in the 20s and 30s. Therefore, plans have been devised to prepare various policies that allow young people to select long-term boarding. This study analyzed the determinants of long-term boarding decisions among students enrolled in the Maritime College of 'M' University and verifies the relationship with the desired boarding period. Additionally, the crew composition (CC), long-term planning (LP), work environment (WE), and family environment (FE) were derived as the determinants of long-term boarding recognized by prospective seafarers. Among them, LP and WE significantly affect the desired boarding period, thus suggesting that the stronger the perception toward long-term planning and the more insensitive one is to the work environment, the longer is the desired boarding period. In terms of group differences in the perception of long-term boarding, analysis results show that the several determinants of long-term boarding are recognized differently depending on gender. This study may facilitate the preparation of factors and group-specific policy measures to promote long-term boarding among prospective seafarers.

• Proceedings of the Materials Research Society of Korea Conference
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• 2000.05a
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• pp.53-76
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• 2000

Multi-color organic electroluminescent (EL) displays have already been commercialized, and the simple extensions of present technologies on organic EL can not be a target for basic research anymore. Future prospect of research on organic electroluminescent devices are described from the view point of possible future break-through. Three aspects, perspective for further increase of device efficiencies, possibility of simplified device structures and possible use of thick organic layers, are discussed.

• 한국생물공학회:학술대회논문집
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• 2005.04a
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• pp.590-590
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• 2005

• Journal of the Korean Data and Information Science Society
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• v.14 no.1
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• pp.93-101
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• 2003

Computation with fuzzy numbers is a prospective branch of a fuzzy set theory regarding the data processing applications. In this paper we consider an open problem about distributivity of fuzzy quantities based on the extension principle suggested by Mare (1997). Indeed, we show that the distributivity on the class of fuzzy numbers holds and min-norm is the only continuous t-norm which holds the distributivity under t-norm based fuzzy arithmetic operations.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2004.04a
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• pp.518-523
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• 2004

PLGA was suggested. Under various conditions, their diameters and porosity as well as mechanical strength were evaluated. In addition to those, cell(chondrocyte) proliferation and formation of extracelluar matrices were also investigated along with the conventional membrane type PLGA scaffolds for the potential use in tissue engineering. As conclusions, this type of scaffold showed a potential of application to tissue engineering in view of mechanical stability as well as cellular responses.

• 대한예방의학회:학술대회논문집
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• 2005.10a
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• pp.496-496
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• 2005

• Journal of the Speleological Society of Korea
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• no.82
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• pp.8-12
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• 2007

In this paper, we have investigated the characteristics of the magnetic abrasive using sludge on polishing of internal finishing of seamless stainless steel tube applying magnetic abrasive polishing. Either green carborundum(GC) grain was used to resin sludge at a low temperature, and the sludge of magnetic abrasive powder was synthesized and crushed into 200 meshes. Surface roughness was measured before and after polishing, and more than 38% of improvement of surface roughness was achieved when grain was used under a specific condition. Even though some degree of surface roughness due to deeper scratches still exist, but the result showed a prospective magnetic abrasive polishing using sludge with green carborundum grains.