• Journal of Periodontal and Implant Science
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• 제50권6호
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• pp.368-378
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• 2020

Purpose: Vitamin D deficiency may cause bone loss and increased inflammation, which are well-known symptoms of periodontal disease. This study investigated whether serum 25-hydroxyvitamin D (25(OH)D) levels are associated with periodontal disease status and tooth loss. Methods: Cross-sectional data from 5,405 individuals aged ≥50 years (2,253 males and 3,152 females) were obtained from the 2008-2010 Dong-gu study, a prospective cohort study of risk factors for chronic diseases. Periodontal examinations were conducted to evaluate the number of remaining teeth, the periodontal probing depth (PPD), the clinical attachment level (CAL), and bleeding on probing. The percentages of sites with PPD ≥4 mm and CAL ≥4 mm were recorded for each participant. The severity of periodontitis was classified using the Centers for Disease Control and Prevention and the American Academy of Periodontology case definitions. Serum 25(OH)D levels were classified as reflecting severe deficiency, deficiency, insufficiency, or sufficiency. Multivariate linear regression analysis was performed to assess the associations of serum 25(OH)D levels with periodontal parameters and the number of remaining teeth after adjusting for confounders including age, smoking status, alcohol consumption status, month of blood collection, and physical activity. Multivariate logistic regression was used to evaluate the association between serum vitamin D levels and severe periodontitis. An overall statistical analysis and a stratified analysis by sex were performed. Results: Overall, the rates of severe deficiency, deficiency, insufficiency, and sufficiency were 6.5%, 67.9%, 22.4%, and 3.2%, respectively. After adjustment for confounders, vitamin D levels were directly associated with the number of remaining teeth, an association that was significant in males, but not in females. Sufficient serum 25(OH)D was associated with a low frequency of severe periodontitis. Conclusions: This population-based cross-sectional study indicates that low serum 25(OH) D is significantly associated with tooth loss and severe periodontitis in Koreans aged 50 years and older.

• 한국초등과학교육학회지:초등과학교육
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• 제41권1호
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• pp.65-78
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• 2022

이 연구의 목적은 예비 교사들을 대상으로 과학적 자기 효능감 척도의 타당도 검증과 배경 변인에 따른 잠재평균분석을 통해 예비 교사 교육에서의 시사점을 도출하는 것이다. 이를 위하여 187명의 예비 교사들을 대상으로 과학적 자기 효능감 척도(Tark, 2011)를 활용한 사전 검사를 진행하였다. 그리고 탐색적 요인분석을 통해 도출한 결과를 바탕으로 전문가 협의회를 실시하여 문항을 보완한 후 354명의 예비 교사들에게 본 검사를 실시하였으며 탐색적 요인분석과 확인적 요인분석을 실시하였다. 분석 결과 사전 검사에는 과학적 자기 효능감 척도에 예비 교사들은 3개 요인으로 응답하였으나 2개 문항의 타당도가 낮게 나타났다. 수정한 척도를 활용하여 본 검사를 실시한 결과 29개 문항이 의도한 3개 요인에 적재되었음을 확인하였으며 각 요인별 신뢰도는 .882~.886으로 나타났다. 예비 교사들의 배경 변인에 따른 잠재평균분석을 실시하여 효과 크기를 도출한 결과, 성별에 따라서는 자기조절효능감(Cohen's d > .5)은 여성이 자신감(Cohen's d > .3)은 남성이 유의미하게 높은 결과를 보여주었다. 진로 계열과 과학에 대한 선호도 변인에서는 과제곤란도선호 요인과 자기조절효능감 요인에서 자연(이공)계열, 그리고 과학에 긍정적 선호를 선택한 예비 교사가 유의미하게 큰 효과크기 차이(Cohen's d > .8)를 보여주었다. 이 연구 결과를 토대로 수정된 과학적 자기 효능감 척도를 활용하면 예비 교사들의 과학 과목에 대한 자기 효능감을 정확히 진단하는데 큰 기여를 할 것이라 판단된다. 또한 과학적 자기 효능감 검사 결과를 바탕으로 예비 교사들의 과학적 자기 효능감을 효과적으로 향상시킬 수 있는 교육과정 및 교육 내용 개편에도 기여할 수 있을 것이다.

• 한국식품영양학회지
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• 제35권6호
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• pp.435-444
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• 2022

In vitro digestibility and protein digestibility corrected amino acid scores (PDCAAS) were investigated to verify the availability of protein in various Rhizopus oligosporus fermented products of domestic soybean (Glycine max L.) cultivars. Danbaegkong (DBK), Daepung (DP), Daewonkong (DWK), Saedanbaek (SDB), Seonyu (SY), and Cheongja4ho (CJ4) were used as raw samples, which were fermented using commercially available Rhizopus oligosporus for 48 h. All cultivars showed increased crude protein content after fermentation. The crude protein content of DBK and SDB was significantly higher than that of the other samples (55.12% in DBK and 54.22% in SDB) (p<0.001). CJ4 had the highest alanine content of 28.88 mg/g (p<0.001), and no significant difference in cysteine content was detected among the cultivars. In most of the fermented samples, the in vitro digestibility was 0.9 or higher, indicating high protein in the fermented samples. However, it is considered that restrictions on digestion are low. In DWK, the amino acid content and PDCAAS, which together indicate protein quality, were 0.917 and 0.855, respectively, confirming that it was the best cultivar to provide the raw material for fermentation. In conclusion Rhizopus oligosporus fermented soybean products can be considered a prospective source of protein with high utility value.

• 대한한의학방제학회지
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• 제30권4호
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• pp.241-248
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• 2022

Objective : The purpose of this trial is to observe the preliminary effects of Salvia plebeia (SP) extract on quality of life in patients with solid cancer. Methods : This is a prospective, open-label, single-arm, and single-dose clinical trial. Twenty participants who have been diagnosed with solid cancer between the ages of 20 and 65 will be included. All participants will be administered SP granules for 12 weeks. Data will be collected at 4, 8, and 12 weeks after enrollment. The primary outcome is quality of life, using the Korean version of the Functional Assessment Cancer Therapy-General questionnaire. Secondary outcomes include tumor markers in blood tests for each cancer type, soluble programmed death-ligand 1, the percentage of natural killer cells among lymphocytes, ratio of T-helper and T-suppressor cells, ratio of total T, T-helper, T-suppressor, and B cells in lymphocytes, level of C-reactive protein, and tumor size via radiology examination. Safety will be assessed by clinical laboratory tests and monitoring of adverse events. Discussion : This study aims to observe the effects of an oral administration of SP preparations in patients with solid cancer on changes in quality of life and an improvement in immune function. It is expected to provide objective evidence of the effect and safety of SP for patients with solid cancer. Trial registration: KCT0007315 (Clinical Research Information Service)

• Journal of Korean Neurosurgical Society
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• 제65권5호
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• pp.751-757
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• 2022

Objective : Tumours of the brain are a rare occurrence accounting for approximately 2% of all neoplasms in adults. Few studies have been done in Nigeria on the profile of brain tumours. The aim of this study is to determine the profile of brain tumours in general and determine the change in Kanofsky Performance Score (KPS) after treatment. Methods : This is a prospective hospital-based study in Kaduna. All consecutive patients over 18 years of age with diagnosis of brain tumours from January 2016 to December 2019 were included in the study. Demographic and clinical data was collected using a proforma during the study. Patients who received treatment were followed up for 12 months. The primary outcome data was the difference in the quality of life as measured by KPS at the point of first contact and at 1-month after treatment and at 12-month follow up. Data obtained was analysed with SPSS version 25.0 for Windows. Descriptive statistics was done to determine the profile. Paired t-test at 95% confidence interval was done to check for significant correlation between the mean KPS. Results : A total of 39 consecutive patients were included in the study. There was a slight male preponderance with a M : F of 1.17 : 1. Meningioma and metastasis were more common in females while gliomas and pituitary tumours were more common in males. The mean age of patients was 49.8 years and standard deviation of 11.8 years. Pituitary tumours were the most common tumours. The most common location of the tumour was frontal lobe followed by the pituitary gland. The mean duration of symptoms before neurosurgical consultation was 38 weeks. The most common presenting symptoms of patient with brain tumour was headache. The quality of life improve compare to the baseline in 81% of patient at discharge and at 1 year follow up. The overall mortality rate was 25.6%. Conclusion : The most common brain tumour in our study is pituitary tumour. Most patients present late. The most common presenting symptoms is headache. There is significant improvement in the KPS of patients following treatment. The overall mortality rate at 1-year post treatment is 25.6%.

• 자원환경지질
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• 제55권4호
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• pp.399-406
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• 2022

2050 탄소중립이라는 메가트렌드에 맞추어 청정에너지기술에 사용되는 핵심광물의 양이 파리기후변화협약기반 시나리오와 2050 탄소중립기반 시나리오에 따르면 각각 4배, 6배 증가하는 것으로 평가된다. 그리고, 한국의 경우, 2차전지에 사용되는 배터리 공급망에서 볼 때 배터리물질과 배터리셀팩을 제조하는 미드스트림에서는 강점을 보이나 원료물질을 제공하고 처리하는 업스트림에서는 어려움을 겪고 있다. 한국지질자원연구원은 이러한 배터리원료광종의 업트스림 리스크에 대응하기 위해 리튬, 니켈, 코발트에 대한 확보전략을 수립하고 탐사기술을 개발하고 있다. 리튬의 경우, 경상북도 울진에서 2020년부터 탐사를 진행하고 있고 2021년말 제반탐사자료를 종합하고 3D모델을 구축하여 정밀탐사대상지를 선정했으며, 2022년에는 정밀탐사대상지를 중심으로 리튬페그마타이트의 부존잠재량을 평가할 예정이다. 니켈의 경우, 과거 탐광을 했던 10여개 니켈황화물광상을 대상으로 예비조사를 통하여 2022년말 탐사대상지를 선정할 예정이다. 코발트의 경우, 남한에서는 유일하게 보국코발트가 알려져있지만 열수광상으로 코발타이트가 산출되었다는 기록만 있을뿐 세계적인 코발트광상(예. 모로코 Bou Azzer)의 성인을 보면, 초염기성암과 관련된 사문암체와 화강암의 접촉부에서 코발트광체가 발견되어 국내에서는 코발트탐사를 위한 프로토콜을 정립할 예정이다.

• 한국의상디자인학회지
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• 제24권2호
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• pp.117-129
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• 2022

In terms of junior high school girls' growth patterns during early adolescence, unlike childhood when relatively balanced growth patterns are found and high school years in which the normal adult body type is almost reached, junior high school girls display imbalanced and rapid growth. In fact, diverse size changes by body part occur with a significant difference among individuals. Therefore, it has been difficult for junior high school students to select their exact size when buying a school uniform. This study attempted to develop winter blouse and skirt patterns reflecting the latest comfortable and active school uniform trends, using middle school girl avatars of various body shapes. Skirt and blouse pattern-drawing methods and margins differed. Based on such results, research prototypes were prepared. Then, virtual wear prospective drawings, clothing pressure, and appearance were assessed by body shape. Skirts were assessed with 22 factors while blouses were analyzed with 25 factors. Then, correlations between skirts and blouses were analyzed. According to the analysis, the reason why the dart & pleats position and margin were rated low was confirmed. In a virtual wear assessment on skirt patterns by body shape, a significant difference was found in all categories except for position of the hip circumference, margin of the hips, width of the skirt, and appropriateness of waist line position. The virtual wear assessment on the blouse patterns by body shape also revealed a significant difference in all categories but fit and shape pf the back part. In blouses, a significant difference was observed around shoulders and waist in type 1 and around the belly in type 2. On the contrary, for skirts, a significant difference was found around the hips and waists in type 1 and type 2. Therefore, these factors should be considered in making blouses and skirts. The above results suggested that skirt and blouse patterns should vary by body shape. It is anticipated that there should be further studies comparing brand-name school uniforms for high school girls and school uniforms by body shape.

• 한국엔터테인먼트산업학회논문지
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• 제15권6호
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• pp.55-70
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• 2021

본 연구는 국내 엔터테인먼트 산업을 대상으로 하여 다음의 두 가지 내용을 실증적으로 분석하는 것을 목적으로 한다. 우선, 기업의 현금보유수준이 엔터테인먼트 기업의 재무적 가치측면에서 어떠한 영향을 미치는지를 분석한다. 그 다음으로, 기업의 어떠한 특성들이 엔터테인먼트 기업의 현금보유수준에 영향을 미치는지를 분석한다. 이를 검증하기 위하여 2000년부터 2018년의 총 19년 동안의 장기간 표본을 이용하여 한국거래소 유가증권시장 및 코스닥시장에 상장된 엔터테인먼트 기업들을 대상으로 분석을 진행하였다. 분석의 주요 결과는 다음과 같다. 첫째, 엔터테인먼트 기업의 현금보유수준이 비엔터테인먼트 기업에 비하여 더 높은 것으로 나타났다. 둘째, 엔터테인먼트 기업의 현금보유수준의 증가는 기업가치를 증가시키는 작용을 하고 있었다. 셋째, 기업의 특성 변수 중에서 부채비율 및 수익성이 현금보유수준에 큰 영향을 미치는 것으로 나타났다. 부채비율이 낮고 수익성이 높을수록 엔터테인먼트 기업은 현금을 더 많이 보유하는 것이 발견되었다. 이러한 결과는 다음과 같은 시사점을 준다. 첫째, 엔터테인먼트 산업은 향후 투자기회가 높은 것으로 주식시장에서 평가받고 있고, 이에 따라 높은 현금보유수준은 높은 기업 가치로 연결된다. 둘째, 엔터테인먼트 기업의 현금보유는 부채조달의 대용수단으로 사용되어 자금조달이 필요한 경우를 대비하고 있으며, 엔터테인먼트 기업의 현금보유와 관련한 대리인문제는 낮은 것으로 판단된다.

• 감성과학
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• 제25권3호
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• pp.91-106
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• 2022

본 연구에서는 온라인 패션시장에서 소호 패션쇼핑몰의 성공적 창업의 성장 과정을 알아보기 위해 현재 성공적으로 운영되고 있는 4개 소호 패션쇼핑몰을 대상으로 기업가 과정을 창업기회포착, 사업모델, 위기관리 및 사업성과 등 3개 단계로 구분하여 분석하였다. 사례연구의 결과는 다음과 같다. S사는 짧은 경력의 창업자가 패션감각과 기업가정신으로 전자상거래를 창업한, 가격경쟁력과 디자인력, 다양한 상품구색을 갖춘 캐주얼 쇼핑몰로 데이터 관리/분석, 유통채널 다각화를 통해 성장한 사례이다. B사는 짧은 경력의 창업자가 SNS 네트워크 역량과 기업가정신으로 제조업/전자상거래를 창업한, 아이템 경쟁력과 스타트업 특성을 갖춘 컨템포러리 쇼핑몰로 브랜드 정체성 확립, 시장 확장을 통해 성장한 사례이다. M사와 C사는 보다 긴 경력의 창업자가 브랜드 인지도가 있는 소호 패션쇼핑몰 사례이다. M사는 풍부한 경력과 디자인 정신의 창업자가 감성적/감각적 패션디자이너 브랜드를 창업하여 기업 지평을 넓히는 다양한 활동을 통해 성장하였고, C사는 디자인 역량과 기업가정신의 창업자가 감성 표현에 집중한 럭셔리 패션브랜드를 창업하여 적극적인 고객관리를 통한 브랜드인지도 및 매출 확보 등을 통해 성장한 사례이다. 본 연구 결과는 소호쇼핑몰 예비창업자나 창업과정의 교육 및 연구에서 기초자료로 활용될 수 있다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제23권1호
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• pp.19-28
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• 2023

Background: Fearful and anxious patients who find dental treatment intolerable without sedative and analgesic support may benefit from moderate sedation. Target controlled infusion (TCI) pumps are superior to bolus injection in maintaining low plasma and effect-site concentration variability, resulting in stable, steady-state drug concentrations. We evaluated the safety and efficacy of moderate sedation with remifentanil and propofol using TCI pumps in non-hospital dental settings. Methods: A prospective chart review was conducted on 101 patients sedated with propofol and remifentanil using TCI pumps. The charts were completed at two oral surgeons and one general dentist's office over 6 months. Hypoxia, hypotension, bradycardia, and over-sedation were considered adverse events and were collected using Tracking and Reporting Outcomes of Procedural Sedation (TROOPS). Furthermore, patient recovery time, sedation length, drug dose, and patient satisfaction questionnaires were used to measure sedation effectiveness. Results: Of the 101 reviewed sedation charts, 54 were of men, and 47 were of women. The mean age of the patients was 40.5 ±18.7 years, and their mean BMI was 25.6 ± 4.4. The patients did not experience hypoxia, bradycardia, and hypotension during the 4694 min of sedation. The average minimum Mean Arterial Pressure (MAP) and heartbeats were 75.1 mmHg and 60.4 bpm, respectively. 98% of patients agreed that the sedation technique met their needs in reducing their anxiety, and 99% agreed that they were satisfied with the sedation 24 hours later. The average sedation time was 46.9 ± 55.6 min, and the average recovery time was 12.4 ± 4.4 min. Remifentanil and propofol had mean initial effect-site concentration doses of 0.96 µ/.ml and 1.0 ng/ml respectively. The overall total amount of drug administered was significantly higher in longer sedation procedures compared to shorter ones, while the infusion rate decreased as the procedural stimulus decreased. Conclusion: According to the results of this study, no patients experienced adverse events during sedation, and all patients were kept at a moderate sedation level for a wide range of sedation times and differing procedures. The results showed that TCI pumps are safe and effective for administering propofol and remifentanil for moderate sedation in dentistry.