• Asian-Australasian Journal of Animal Sciences
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• v.25 no.8
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• pp.1089-1095
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• 2012

Neonatal Fc receptor (FcRn) gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G (IgG) and is responsible for IgG transport and stabilization. In this report, the 8,900 bp porcine FcRn genomic DNA structure was identified and putative FcRn protein included 356 amino acids. Alignment and phylogenetic analysis of the porcine FcRn amino acid sequences with their homologies of other species showed high identity. Tissues expression of FcRn mRNA was detected by real time quantitative polymerase chain reaction (Q-PCR), the results revealed FcRn expressed widely in ten analyzed tissues. One single nucleotide polymorphism (SNP) (HQ026019:g.8526 C>T) in exon6 region of porcine FcRn gene was demonstrated by DNA sequencing analysis. A further analysis of SNP genotypes associated with serum Classical Swine Fever Virus antibody (anti-CSFV) concentration was performed in three pig populations including Large White, Landrace and Songliao Black pig (a Chinese indigenous breed). Our results of statistical analysis showed that the SNP had a highly significant association with the level of anti-CSFV antibody (At d 20; At d 35) in serum (p = 0.008; p = 0.0001). Investigation of expression and polymorphisms of the porcine FcRn gene will help us in further understanding the molecular basis of the antibody regulation pathway in the porcine immune response. All these results indicate that FcRn gene might be regarded as a molecular marker for genetic selection of anti-CSFV antibody level in pig disease resistance breeding programmes.

• Asian-Australasian Journal of Animal Sciences
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• v.26 no.4
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• pp.564-572
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• 2013

Two trials were conducted to investigate the effect of decreasing the crude protein (CP) content of diets for finishing pigs containing two levels of available lysine on nutrient digestibility, nitrogen (N) balance and production performance. Ten finishing diets containing five levels of CP (on average 144, 155, 168, 182 and 193 g/kg fresh basis) and two levels of available lysine (6.9 and 8.2 g/kg fresh basis) were formulated. The diets were offered to pigs on a performance trial (n = 800 Large White (LW)${\times}$Landrace (LR) pigs) from 10 wk of age until finish at 21 wks+5 d of age. Average daily gain (ADG), average daily feed intake (ADFI) and feed conversion ratio (FCR) were calculated. In addition, a digestibility/N balance trial was conducted using pigs (n = 80 $LW{\times}LR$) housed in metabolism crates. Digestibility of dry matter (DM), CP, oil, fibre and energy was determined. N balance values were determined through analysis of N content of urine and faeces ('as determined'). N balance values were also calculated using ADG values and assuming that 16% of growth is protein deposition ("as calculated"). Pig performance was poor between 10 and 13 wk of age which indicated that the dietary treatments were nutritionally inadequate for pigs less than 40 kg. There was a significant (p<0.01) quadratic effect of increasing CP level on feed intake, ADG and FCR from 10 to 13 wk which indicated that the lower CP levels did not supply adequate levels of essential or non-essential amino acids. There was no effect of increasing available lysine level throughout the early period, which in conjunction with the response in older pigs, suggested that both 8.2 and 6.9 g/kg available lysine were insufficient to drive optimum growth. There was a positive response (p<0.05) to increasing available lysine level from 13 wk to finish which indicated that 6.9 g/kg available lysine was not adequate for finishing pigs. Energy digestibility decreased with decreasing CP level of diets containing 6.9 g/kg available lysine which may be attributed to the higher fibre content of the lower CP diets. Nitrogen excretion (g/d) was lowered when dietary CP was reduced regardless of whether the values were determined through balance or calculated using ADG. Calculated N excretion decreased linearly (p<0.001) and quadratically (p<0.001) with decreasing dietary CP content. When the N balance figures calculated in this study were compared with those quoted in the Northern Ireland and English Nitrates Directive Action Programmes, N excretion was less per pig (wean to finish) offered a 169 g/kg CP, 8.2 g/kg available lysine diet (2.39 kg vs 3.41 kg (Northern Ireland) and 2.93 kg (England)).

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5349-5357
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• 2015

Background: Breast cancer is the most common cancer and the leading cause of cancer mortality among women of all ethnic and age groups in Malaysia. Delay in seeking help for breast cancer symptoms is preventable and by identifying possible factors for delayed diagnosis, patient prognosis and survival rates could be improved. Objectives: This narrative review aimed to understand and evaluate the level of in-depth breast cancer knowledge in terms of clinical breast examination and breast self-examination, and other important aspects such as side-effects and risk factors in Malaysian females. Since Malaysia is multicultural, this review assessed social perceptions, cultural beliefs and help-seeking behaviour in respect to breast cancer among different ethnic groups, since these may impinge on efforts to 'avoid' the disease. Materials and Methods: A comprehensive literature search of seven databases was performed from December 2015 to January 2015. Screening of relevant published journals was also undertaken to identify available information related to the knowledge, perception and help-seeking behaviour of Malaysian women in relation to breast cancer. Results: A total of 42 articles were appraised and included in this review. Generally, women in Malaysia had good awareness of breast cancer and its screening tools, particularly breast self-examination, but only superficial in-depth knowledge about the disease. Women in rural areas had lower levels of knowledge than those in urban areas. It was also shown that books, magazines, brochures and television were among the most common sources of breast cancer information. Delay in presentation was attributed mainly to a negative social perception of the disease, poverty, cultural and religion practices, and a strong influence of complementary and alternative medicine, rather than a lack of knowledge. Conclusions: This review highlighted the need for an intensive and in-depth breast cancer education campaigns using media and community health programmes, even with the existing good awareness of breast cancer. This is essential in order to avoid misconceptions and to frame the correct mind-set about breast cancer among women in Malaysia. Socio-cultural differences and religious practices should be taken into account by health care professionals when advising on breast cancer. Women need to be aware of the risk factors and symptoms of breast cancer so that early diagnosis can take place and the chances of survival improved.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.8
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• pp.3435-3442
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• 2015

Objective : To provide background information for strengthening cervical cancer prevention in the Pacific by mapping current human papillomavirus (HPV) vaccination and cervical cancer screening practices, as well as intent and barriers to the introduction and maintenance of national HPV vaccination programmes in the region. Materials and Methods: A cross-sectional questionnaire-based survey among ministry of health officials from 21 Pacific Island countries and territories (n=21). Results: Cervical cancer prevention was rated as highly important, but implementation of prevention programs were insufficient, with only two of 21 countries and territories having achieved coverage of cervical cancer screening above 40%. Ten of 21 countries and territories had included HPV vaccination in their immunization schedule, but only two countries reported coverage of HPV vaccination above 60% among the targeted population. Key barriers to the introduction and continuation of HPV vaccination were reported to be: (i) Lack of sustainable financing for HPV vaccine programs; (ii) Lack of visible government endorsement; (iii) Critical public perception of the value and safety of the HPV vaccine; and (iv) Lack of clear guidelines and policies for HPV vaccination. Conclusion: Current practices to prevent cervical cancer in the Pacific Region do not match the high burden of disease from cervical cancer. A regional approach, including reducing vaccine prices by bulk purchase of vaccine, technical support for implementation of prevention programs, operational research and advocacy could strengthen political momentum for cervical cancer prevention and avoid risking the lives of many women in the Pacific.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.3
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• pp.1213-1217
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• 2015

Background: Gastric cancer is the second most common cause of cancer- related deaths worldwide and ranks $11^{th}$ or $14^{th}$ among all deaths. Patients with advanced disease require supportive care along with the medical and/or surgical treatment. Aim: To assess the need for palliative care for patients with advanced tumours along with standard clinical therapy. Materials and Methods: Eighty-four patients with metastatic (stage 4) gastric cancer, including both patients who had received surgical treatment or not, were followed up in Bagcilar Training and Research Hospital, Division of Medical Oncology between 2011 and 2014. They were categorised as supportive care (-) (Group 1, n=37) and (+) groups (Group 2, n=47) and evaluated retrospectively. Results: Demographic characteristics of the patients were as follows: mean age, Group 1, $65.2{\pm}10.5$ years, Group $2,63.7{\pm}11.3$ years; male/female ratio, Group 1, 21/16, Group 2, 28/19; distribution of Eastern Cooperative Oncology Group (ECOG) performance scores of 0 and 1, Group 1, ECOG 0 (n=9) and 1 (n=14), Group 2, ECOG 0 (34) and 1 (n=13) (p<0.0001); patients receiving second-line, Group 1 (n=7) and Group 2 (n=22) (p<0.008) or third - line chemotherapy,Group 2 (n=6) (p<0.02); mortality rates, Group 1, (n=28; 75.6%) and Group 2 (n=30; 63.8%); progression-free survival (PFS) rates, Group 1, $17.4{\pm}6$ weeks, Group 2, $28.3{\pm}16.2$ weeks; statistically significant overall survival rates, Group 1, $20.8{\pm}8.2$ weeks and Group 2, $28.3{\pm}162$ weeks (p<0.01). Conclusions: The supportive care team (medical oncologist, general surgeon, internal medicine specialist, algologist, psychiatrist and radiologist) can play a role in the treatment of metastatic gastric tumours, with improvements shown in terms of the performance status of cases, eligibility of patients to be on chemotherapy programmes for longer duration and overall survival rates in Turkey.

• Journal of Korean Society of Forest Science
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• v.77 no.2
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• pp.242-251
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• 1988

Private forestland in Korea occupies about 48 percent of the total land area. But, the ownership size is too small to expect self-supporting management of forestowners. In order to improve individual management of the small-sized forest through the to the state of self-support, a cooperative forest management has been demanded, enlargement of the size of the management units by combining the different individual management units. The cooperative management of the private forest is to combine forestry production factors such as forestland, labor-power, and capitals according to the agreement. For the cooperative forest management, a proper plan should be established and well-trained working-crew should be produced. In addition, forestry facilities should be provided and operated jointly. Though the cooperative forest management by owners is considered to be favorable theoretically, it is difficult for forestowners including many nonresidents to organize the forest management cooperatives without outside help. Therefore, intensive pulblication and extension programmes are required and a financial support by the government should be followed.

• Journal of Korea Technology Innovation Society
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• v.18 no.2
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• pp.358-386
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• 2015

The aim of this paper is to evaluate policy impact of Inno-biz verification and Venture verification, especially focusing on the complementarity effect according to the overlapped support in Korean ICT industry. Alongside the implementation of various government innovation policies, discussions regarding evaluations of such policies have been consistently undertaken in economics, because it is very important to evaluate whether public policies have played a proper role. However, one of the distinguished point of this research from previous studies is that this paper not only includes evaluations of a single policy, but also the discussion about interaction between different innovation policies. The main result of this paper is that, in the case of overlapping homogeneous policies such as Inno-biz and venture verification, the complementarity effect is negative. Compared with previous studies, the uniqueness of this research is as follows. First, deviating from the view of previous studies that focused on the evaluation of a single policy, this paper has considered interactions and the complementarity effect of innovation policy through "policy mix," an economic term. Second, based on this concept, the paper suggests an analysis framework for the evaluation of interactions and the complementarity effect of innovation policy.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.8
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• pp.5287-5295
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• 2015

This study was conducted to identify the related factors of cancer preventive behaviors for adolescent smokers. Data were collected from September 1st 2012 to March 31st 2013 of 200 adolescent smokers who were participating in smoking cessation school at W hospital in B city. As a results, there were significant differences in cancer preventive behaviors by grade, religion, benefit, barrier, perceived health status, daily living, alcohol, exercise, nicotine dependency, first smoking age, smoking duration and non-smoking intention. Cancer preventive behaviors were weakly negative related to knowledge about cancer, And there is weakly positive correlation between cancer preventive behaviors and attitude about cancer. Meaningful variables which explain cancer preventive behaviors were daily living, barrier, grade, exercise, benefit, knowledge about cancer, smoking cessation intention in order. Total explanation power was 30.6% and daily living has most explanation power. In conclusion, It is necessary to encourage sound hobbies and exercise instead of smoking for adolescent smokers in their daily living. And health education programmes, based on the grade and smoking cessation intention of adolescent smokers, need to be developed to emphasize the benefit of cancer preventive behaviors, and to decrease barriers against those behaviors.

• Korean Journal of Social Welfare
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• v.56 no.1
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• pp.127-153
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• 2004

In the absence of a male provider the state must decide how far and under what conditions it will provide for the mother and her children. In the case of lone mothers, there are three main possible sources of income: the labour market, the absent father, and the state. However, the relative proportions of these three sources vary significantly from country to country as well as from individual to individual within the group of lone parents. Until very recently the UK has been alone among countries of the EU in allowing lone parents to draw benefits without making themselves available for work so long as they have dependent children. However, in the 1990s, the UK government introduced major changes to his policies regarding lone parents. The UK government attempted to restrict the role of the state as a source of income for lone parent families. At the beginning of the 1990s, the emphasis in the UK was put on securing more money from 'absent fathers' to maintain. However, the policy was unsuccessful and by the mid-1990s attention to the only other possible source of income for lone parent families, the labour market, was stepped up, notwithstanding the ambivalence of politicians about the desirability of women with young children entering employment. From 1998 the Labour government introduced a series of reforms aimed at reducing both worklessness and poverty by raising welfare payments to families both in and out of work, improving financial incentives to work and introducing a more proactive welfare system. The results presented here suggest that these policies have raised the employment rates of lone parents by around 5 percentage points, or 80,000. These employment gains have come from a welfare reform package that does not require lone parents to search for jobs, or uses time limits in welfare programmes. In addition these gains have been achieved despite generous increases in welfare payments for lone parents who do not work. These earnings gains combined with the more generous welfare are making rapid progress in reducing lone parents' poverty.

• Korean Journal of Social Welfare
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• v.56 no.1
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• pp.155-179
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• 2004

This study is about the effectiveness and activation strategies of vacational training programme for the disabled guided by the Ministry of Labour and the Korea Employment Promotion Agency for the Disabled(KEPAD). This research employed quantitative approach. The quantitative research used the samples of 853 disabled people who had finished vocational training programme during recent 3 years. In this research the effectiveness is categorized into two ; product effectiveness and employment effectiveness. Product effectiveness is influenced by the kind of train-center, train-area, train-length. The KEPAD, non-IT job area and train-period over 6 month are more effective. Employment effectiveness is significantly influenced by demo-sociological factor rather than disability factor. Especially the kind of train-center is very important to be employed for the disabled. This implicates that choice of train-center by the disabled and effective management of it by the public sector is very important in developing employment. Effective management, stated above, includes reengineering programmes and functions accountable to the need form the trainee, bridging the gap among train-centers in terms of performance, differentiation of financial support according to the product to save the public fund, encouraging one special programme in one train-center.