• Journal of Biomedical Engineering Research
• /
• v.18 no.3
• /
• pp.291-299
• /
• 1997

As a microimaging device detecting gamma rays emitted from small lesions or tumors during operation, the intraoperative surgical probe has been proposed and is now under development. We have designed a multipurpose portable gamma prove system and evaluated the performance both for the absolute counting purpose of residual radioactivities and for the localizing capability of gamma events using the NaI(Tl) crystal and two types of photomultiplier tubes(PMTs). Counting efficiencies in the range of routine clinical use of radiation dose were measured using the assembly of single channel PMTs and 0.5 inch thick NaI(Tl) crystal of 1 inch diameter. The positioning of gamma events for imaging purpose requires the multiple channel PMTs with appropriate positioning electronics. We have designed a simple and reliable positioning circuit based on the concept of modified Anger. In preliminary experiments using the multiple channel PMT of 3 inch diameter and the dim lighth source, we were able to trace and localize the correct position with reduced positioning error by the use of two multiplier/divider chipset and simplified peripherals. The energy resolutions for the counting gamma probe measured as full width at half maximum(FWHM) for Cs-137, F-18, Tc-99m were 12%, 13%, and 36%, respectively. The spatial resolution for the imaging gamma probe measured as FWHM for green LED was 2.9 mm. The results indicate that the currently developing probe is very promising and could be very useful for many applications in nuclear medicine. Future studies will include developing collimators, improving interface hardwares, and evaluating the system with clinical data.

• Tribology and Lubricants
• /
• v.35 no.5
• /
• pp.286-293
• /
• 2019

In friction and wear tests that use friction force microscopy (FFM), the wear debris transfer to the tip apex that changes tip radius is a crucial issue that influences the friction and wear performances of films and coatings with nanoscale thicknesses. In this study, FFM tests are performed for bilayer $MoS_2$ film to obtain a better understanding of how geometrical and chemical changes of tip apex influence the friction and wear properties of nanoscale molecular layers. The critical load can be estimated from the test results based on the clear distinction of the failure area. Scanning electron microscopy and energy-dispersive spectroscopy are employed to measure and observe the geometrical and chemical changes of the tip apex. Under normal loads lower than 1000 nN, the reuse of tips enhances the friction and wear performance at the tip-sample interface as the contact pair changes with the increase of tip radius. Therefore, the reduction of contact pressure due to the increase of tip radius by the transfer of $MoS_2$ or Mo-dominant wear debris and the change of contact pairs from diamond/$MoS_2$ to partial $MoS_2$ or Mo/$MoS_2$ can explain the critical load increase that results from tip reuse. We suggest that the wear debris transfer to the tip apex should be considered when used tips are repeatedly employed to identify the tribological properties of ultra-thin films using FFM.

• Journal of the Korean Society for Nondestructive Testing
• /
• v.35 no.5
• /
• pp.291-298
• /
• 2015

An array type probe for monitoring metal tubes is proposed in this paper which utilizes peak value and peak time of a pulsed eddy current(PEC) signal. The probe consists of an array of encircling coils along a tube and the outside of coils is shielded by ferrite to prevent source magnetic fields from directly affecting sensor signals since it is the magnetic fields produced by eddy currents that reflect the condition of metal tubes. The positions of both exciter and sensor coils are consecutively moved automatically so that manual scanning is not necessary. At one position of send-receive coils, peak value and peak time are extracted from a sensor PEC signal and these data are accumulated for all positions to form an array type peak value signal and an array type peak time signal. Numerical simulation was performed using the backward difference method in time and the finite element method for spatial analysis. Simulation results showed that peak value increases and the peak appears earlier as the defect depth or length increases. The proposed array signals are shown to be excellent in reflecting the defect location as well as variations of defect depth and length within the array probe.

• Proceedings of the Korea Air Pollution Research Association Conference
• /
• 1999.10a
• /
• pp.121-123
• /
• 1999

Bio-Aerosol Concentrator Inlets were made to collect particles of which size was $2\mu\textrm{m}$ as aerodynamic diameter or larger. The Concentrator Inlets were designed by using virtual impactors, because the virtual impactors are known for high efficiency. In a virtual impactor, the intake air is typically divided into two streams with the major and the minor flow. In this work, several types of the acceleration nozzles and collection probes were designed. Subsequently, the results were evaluated experimentally. It was found that if controled properly, the velocity can improve substantially the aerosol concentration performance. The diameter of acceleration nozzle and type of collection probe were varied to obtain the optimum design. Subsequently, the different designs were compared respectively and the best design among them was identified. It is expected that this new finding can help improve design of future Aerosol Concentrator for high concentration rate.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.22 no.4
• /
• pp.868-878
• /
• 1998

There are recently increasing needs for precision XYZ-stage in the fields of nanotechnology, specially in AFMs(Atomic Force Microscope) and STMs(Scanning Tunneling Microscope). Force measurements are made in the AFM by monitoring the deflection of a flexible element (usually a cantilever) in response to the interaction force between the probe tip and the sample and controlling the force neasyred constant topography can be obtained. The power of the STM is based on the strong distance dependence of the tunneling current in the vacuum chamber and the current is a feedback for the tip to trace the surface topography. Therefore, it is required for XYZ-stage to position samples with nanometer resolution, without any crosscouples and any parasitic motion and with fast response. Nanometer resolution is essential to investigate topography with reasonable shape. No crosscouples and parasitic motion is essential to investigate topography without any shape distortion. Fast response is essential to investigate topography without any undesirable interaction between the probe tip and sample surface ; sample scratch. To satisfy these requirements, this paper presents a novel XYZ-stage concept, it is actuated by PZT and has a monolithic flexible body that is made symmetric as possible to guide the motion of the moving body linearly. PZT actuators have a very fast response and infinite resolution. Due to the monolithic structure, this XYZ-stage has no crosscouples and by symmetry it has no parasitic motion. Analytical modeling of this XYZ-stage and its verification by FEM modeling are performed and optimal design that is to maximize 1st natural frequencies of the stage is also presented and with that design values stage is manufactured.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.20 no.1
• /
• pp.175-184
• /
• 2016

In this paper, we propose the method to measure the capacitances using not LCR meter but capacitance to voltage(C/V) conversion. And we design the analog MUX circuits that convert 192 channels to 6 MUX channels in order to implement the diagnosis of multi-channel ultrasonic probe. This paper derives the conversion function that converts the digital voltage of each MUX channel to the capacitance using the least squares method because the circuit characteristics that convert the voltage of each MUX channel to the capacitance are different. The developed prototype illustrates the performance test results that the measure times are measured by within 4sec and the measure error rates of maximum, minimum, and average values are within 5% in terms of the repeated measurements of all 192 channels.

• Microbiology and Biotechnology Letters
• /
• v.45 no.4
• /
• pp.358-364
• /
• 2017

Asymmetric PCR preferentially amplifies one DNA strand for use in DNA hybridization studies. Linear-After-The-Exponential-PCR (LATE-PCR) is an advanced asymmetric PCR method which uses innovatively designed primers at different concentrations. This study aimed to optimise LATE-PCR parameters to produce single-stranded DNA of Candida spp. and Aspergillus spp. for detection via probe hybridisation. The internal transcribed spacer (ITS) region was used to design limiting primer and excess primer for LATE-PCR. Primer annealing and melting temperature, difference of melting temperature between limiting and excess primer and concentration of primers were optimized. In order to confirm the presence of single-stranded DNA, the LATE-PCR product was hybridised with digoxigenin labeled complementary oligonucleotide probe specific for each fungal genus and detected using anti-digoxigenin antibody by dot blotting. Important parameters that determine the production of single-stranded DNA in a LATE-PCR reaction are difference of melting temperature between the limiting and excess primer of at least $5^{\circ}C$ and primer concentration ratio of excess primer to limiting primer at 20:1. LATE-PCR products of Candida albicans, Candida parapsilosis, Candida tropicalis and Aspergillus terreus at up to 1:100 dilution and after 1 h hybridization time, successfully hybridised to respective oligonucleotide probes with no cross reactivity observed between each fungal genus probe and non-target products. For Aspergillus fumigatus, LATE-PCR products were detected at 1:10 dilution and after overnight hybridisation. These results indicate high detection sensitivity for single-stranded DNA produced by LATE-PCR. In conclusion, this advancement of PCR may be utilised to detect fungal pathogens which can aid the diagnosis of invasive fungal disease.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.16 no.11 s.102
• /
• pp.1164-1170
• /
• 2005

This paper presents a dual-band, dual-polarized microstrip patch antenna with simple dual-probe feed. The inter-port isolation and cross-polarization are greatly improved by designing feed structure with annular gap between patch and feed-probe. Measured results show that the antenna's inter-port isolation and cross-polarization in each -10 dB return loss bandwidth of $1.84\;GHz\~l.93\;GHz$ and $2.62\;GHz\~2.81\;GHz$ are greater than 21 dB, greater than 22.2 dB and greater than 27 dB, greater than 19 dB, respectively. The antenna gain is about 6.9 dBi in both frequency bands.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.26 no.12
• /
• pp.1058-1063
• /
• 2015

In this article, we propose a near field microwave scanning probe structure in which two short conducting rods are attached to the center of the ridged(H-type) aperture, thereby reducing significantly the beam spot area while maintaining the high transmission efficiency through the output coupling H-type(ridged) aperture. Here the two short parallel conducting rods seem to play an important role of concentrating the transmitted electromagnetic energy through the H-type aperture and so reducing the beam area for high resolution. For validation of the proposed theory, the near field waveguide probe is fabricated according to the simulated results and its return loss characteristics versus frequencies are measured. The comparison between theory and experiment is seen to be in good agreements.

• Proceedings of the Korean Geotechical Society Conference
• /
• 2010.09c
• /
• pp.24-30
• /
• 2010

The void ratio and elastic moduli are design parameters used in geotechnical engineering to understand soil behavior. Elastic and electromagnetic waves have been used to evaluate the various soil characteristics due to high resolution. The objective of this study is to evaluate the void ratio and elastic moduli based on elastic wave velocities and electrical resistivity. The Field Velocity Resistivity Probe (FVRP) is developed to obtain the elastic and electromagnetic wave profiles of soil during penetration. The Piezoelectric Disk Elements (PDE) and Bender Elements (BE) are used as transducers for measuring the elastic wave velocities such as compressional and shear wave velocities. The Electrical Resistivity Probe (ERP) is also installed for capturing the electrical resistivity profile. The application test is carried out on the southern coast of the Korean peninsula. The field tests are performed at a depth of 6~20 m, at 10 cm intervals for measuring elastic wave velocities and at 0.5cm intervals for measuring electrical resistivity. The elastic moduli such as constraint and shear moduli are calculated by using measured elastic wave velocities. The void ratios are also evaluated based on the elastic wave velocities and the electrical resistivity. Furthermore, the converted void ratios by using FVRP are compared with the volumetric void ratio obtained by a standard consolidation test. The comparison shows that the void ratios based on the FVPR match the volume based void ratio well. This study suggests that the FVRP may be a useful device to effectively determine the elastic moduli and void ratio in the field.