• Preventive Nutrition and Food Science
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• v.9 no.2
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• pp.161-166
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• 2004

The effects of kimchis intake on Helicobacter pylori infection in the stomach, the counts of lactic acid bacteria in the large intestine, and bacterial enzymes ($\beta$-glucosidase, $\beta$-glucuronidase) and pH in feces were examined. A total of 20 participants (age range 34 ∼ 57) were assessed for H. pylori infection status by Be urea breath test. Fourteen participants were eliminated because they were H. pylori-negative. This study consisted of 4 consecutive phase, each of which lasted 4 weeks. Three hundred grams of kimchi were administered to H. pylori-infected subjects during the kimchi phase, followed by 4 weeks of control phase. During the control phase, subjects consumed 60 g of kimchi, the minimum amount in their customary diets. All participants were found to be H. pylori-positive during all experimental periods. During the kimchi phase, delta over baseline (DOB) level was lower than during the control phase, although significant difference between the kimchi and control phases were not found (p=0.9439). However, the counts of Lactobacillus sp. and Leuconostoc sp. significantly (p < 0.0005) increased during the kimchi phase. $\beta$-Glucosidase and $\beta$-glucuronidase activities and pH were significantly decreased by kimchi intake compared to control (p=0.000l). These results suggested that kimchi consumption did not show any therapeutic effect on H. pylori in the stomach. However, kimchi seemed to be a good food for colon health, since it increased the beneficial bacteria such as lactobacillus and decreased toxic enzyme ($\beta$-glucosidase and $\beta$-glucuronidase) activity and pH.

• Journal of Korean Academy of Nursing
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• v.35 no.5
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• pp.763-773
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• 2005

Purpose: This study was conducted to determine the effects of a drug misuse and abuse prevention program on knowledge, attitude, and preventive behaviorsrelated to drug misuse and abuse, and depression in low-income elderly women in the urban area. Method: The design of this study was a nonequivalent control group pretest-posttest design. The subjects consisted of 26 in the experimental group and 23 in the control group. The program was performed for about 1 hour, once a week for 5 weeks. Data was analyzed by the SAS(ver.8.02) computer program, and it included descriptive statistics, Fisher's exact test, Mann-Whitney U test, Wilcoxon signed ranks test, and ANCOVA. Result: There were statistically significant differences in knowledge, attitude, and preventive behaviors related to drug misuse and abuse, and depression between the experimental group and the control group. Conclusion: This study showed that this prevention program of drug misuse and abuse is appropriate for low-income elderly women, Therefore this program is recommended as a nursing intervention strategy for the elderly.

• Journal of Society of Preventive Korean Medicine
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• v.7 no.2
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• pp.23-33
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• 2003

In order to study effects of Yukmiziwhang-Whan on the growth of rats, we divided the experimental rats into two groups(Control&Sample groups) and peformed the experimental study. Sample group was administered the extract of Yukmiziwhang-Whan 1.6ml/100g for 4 weeks, and Control group was administered equal dose of normal saline. We measured the body weight, the length of femur and tibia, the level of serum growth hormone, T3, T4, Insulin and testosterone. The results are summarized as follows : 1) The body weight was not changed compared with Control group. 2) The lengths of femur and tibia in the Sample group was longer than that of Control group, but it was not statistically significant. 3) The level of serum growth hormone in the Sample group significantly increased compared with Control group(p<0.05). 4) The level of serum T3 in the Sample group significantly increased compared with Control group(p<0.05) and T4 level was trending toward increasing compared with Control group. 5) The level of serum insulin in the Sample group was trending toward increase compared with Control group. 6) The level of serum testosterone in the Sample group was trending toward decrease compared with Control group. According to the above experimental results, ${\ulcorner}Yukmiziwhang-Whan{\lrcorner}$ are assumed to have effective activity on the growth of rats.

• Korean Journal of Pharmacognosy
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• v.36 no.1 s.140
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• pp.44-49
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• 2005

The protective effects of the DWP-04 [DDB : selenium yeast: glutathione {31.1 : 6.8 : 62.1 (%, w/w)} against hepatotoxicity by carbon tetrachloride $(CCl_4)$ were studied in rats. The rats were intraperitoneally injected with $CCl_4$ (50% in com oil) at initial dose of 1 ml/kg followed by 0.5 ml/kg 3 times during 1 week. The DWP-04 (50, 100 or 200 mg/kg) or its vehicle was administered everyday before the start of $CCl_4$ injection for two weeks. $CCl_4$ induced hepatocelluar degeneration and necrosis, which led to a great increase in serum aminotransferase, alkaline phosphatase activity and serum lipid levels. It was found by biochemical analysis that $CCl_4$ treatment remarkably increased thiobarbituric acid reactive substances and physphatidylcholine hydroperoxide in hepatic tissues and induced antioxidant enzymes such as catalase and superoxide dismutase (SOD). Liver and serum lipids were significantly lower in rats fed on DWP-04 than in rats induced by $CCl_4$ only-treatment. These results suggested that the DWP-04 could be a promising candidate for the protection of liver injury based on the preventive effects against lipid peroxidation and serum biochemical parameters.

• Journal of Life Science
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• v.11 no.6
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• pp.543-553
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• 2001

Lead poisoning is currently one of the major public health problems in industrialized countries. Several chelating agents have been developed and used to treat the lead poisoning. It was recently proposed that garlic, having a large quantity of S-S compounds, may react readily with lead, producing various sulfur componds, and thus provide curative and protective effects on the lead toxicity. The present study was undertaken to evaluate this possibility in experimental animals. The garlic treatment on rats pre-exposed to lead significantly enhanced urinary excretion of lead at a garlic dose of 500 mg/kg and decreased the bloon level of lead at both 250 and 500 mg/kg doses. The administration of grilic 500mg/kg along with lead significantly alleviated the renal histological alterations induced by lead. These results suggest that garilic has a curative as well as a protective effect against lead poisoning , thus it may act as a chelator of lead.

• Journal of Preventive Medicine and Public Health
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• v.53 no.5
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• pp.371-380
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• 2020

Objectives: This study investigated the effects of socio-demographic factors on the decreasing trend in the sex ratio at birth from 1997 to 2017 in Korea. Methods: Data from 10 349 602 live births registered with Statistics Korea from 1997 to 2017 were analyzed. The secondary sex ratio (SSR), defined as the ratio of male to female live births, during the study period (1997-1999 [phase I], 2000-2002 [phase II], 2003-2005 [phase III], 2006-2008 [phase IV], 2009-2011 [phase V], 2012-2014 [phase VI], and 2015-2017 [phase VII]) was calculated according to selected socio-demographic factors, such as parental age, education, occupation, and birth order. Logistic regression models were used to estimate odds ratios (ORs) and 95% confidence intervals for a male birth after adjusting for potential confounders. Results: The SSR gradually decreased from 1.10 (in 1998-2000 and 2002) to 1.05 (in 2013-2016). While a decreasing trend in the SSR was not noted among first births, male-biased sex ratios were prominent among third and higher-order births, for which the highest SSR was 1.46 in 1998. Higher birth order was significantly associated with an excess of male births in phases I-VI (≥third vs. first, OR range, 1.03 to 1.35). Advanced maternal age was significantly associated with an excess of female births in phases II, III, and V (≥40 vs. 20-24 years, OR range, 0.92 to 0.95). Conclusions: This study demonstrated that advanced maternal age and reduction of the artificially-biased SSR among third and higher-order births may partially explain the decreasing trend in the SSR from 1997 to 2017 in Korea.

• Journal of Digital Convergence
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• v.14 no.12
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• pp.537-544
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• 2016

This study was to investigate their relevance between oral health behaviors and number of remaining teeth of the elderly welfare recipients through the fluoride and scaling of the business. Researcher collected 660 subjects over 60 elderly welfare recipients investigated self-administered survey and use denture and number of remaining teeth though oral examination. Increasingly age number of teeth remaining reduced, there is a difference on the number of remaining teeth according to gender, age, the use of oral hygiene products, self diagnosis oral condition, brushing after lunch and showed significant difference(p<0.05). The remaining number of teeth can be prevented by attention and efforts of subjects. Therefore, we investigated convergent effects of oral health behaviors on number of remaining teeth of the elderly, I hope that oral health care program continually provides expansion of preventive treatment and to maintain the provision of health care about vulnerable group.

• Journal of the Korea Institute of Building Construction
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• v.20 no.1
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• pp.73-81
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• 2020

The main purpose of the study is to reduce the accident death rate in the construction industry. To achieve this goal, the safety planning tasks were analyzed and assessed in terms of the importance and preventive effects of the tasks. Through the extensive literature reviews, the safety planning tasks were identified and reviewed by safety managers. based on the safety planning tasks developed in the previous stage, a survey was conducted in order to receive responses by experts with knowledge on the effects and importance of preventive measures for safety. Then, the Importance Performance Analysis(IPA) method was employed to identify the safety manager's tasks that have an effect on performance indicators. Advice and guidance on making the employment rules, etc. (#18) and details about participation and consultation at the Occupational Safety and Health Committee (#16) were found to require revision and improvement of details and guidelines. The effective safety tasks identified are expected to have a critical role in reducing the accident death rate in the construction industry.

• Journal of Ginseng Research
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• v.33 no.2
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• pp.149-154
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• 2009

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation and progressive cartilage and bone erosion. Korean red ginseng (KRG) has been shown to have an anti-inflammatory effect by inhibiting the secretion of inflammatory cytokines like $TNF-{\alpha}$, IL-1, -6, and -8, and $IPN-{\gamma}$. In this study, whether KRG extract has an inhibitory effect on the collagen-inducible development of arthritis in DBA/1J mice was investigated. To induce arthritis, type II collagen emulsified in Complete Freund's Adjuvant was intradermally injected into the base of the tails of mice. Three weeks after the initial injection, a booster injection of type II collagen emulsified in Incomplete Freund's Adjuvant was administered. The oral administration of KRG extract for 8${\sim}$10 weeks at the dose of 300 mg/kg (three days a week) inhibited the development of arthritis in the experimental group, compared to the control group which was given saline. While the administration of KRG extract three times a week demonstrated both preventive and inhibitory effects, the administration of KRG extract once a week had little inhibitory effect. In other studies, the regimen of KRG administration has been shown to decrease the plasma level of inflammatory cytokines like IL-8 and TNF-${\alpha}$, but the plasma levels of these cytokines were not decreased in the present study. The results of the present study suggest that KRG has preventive and inhibitory effects on collagen-induced arthritis.

• Korean Journal of Health Education and Promotion
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• v.25 no.1
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• pp.71-81
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• 2008

Objectives: The purpose of this study was to evaluate the long term effects of school-based oral health program on the decrease of dental caries among elementary school children. Methods: The subjects of this study were total 283 students of one elementary school in Deagu, Korea. They had received school-based oral health programs more than one year since 2004. This school-based oral health program included regular oral examination, fluoride mouthrinsing, pit-and-fissure sealing, APF gel application, tooth brushing instruction and chewing the xylitol tablets. The subjects' oral health status were examined and calibrated by a dentist every year from 2004 to 2007. Results: The change of DMFT index were as follows: (1)The subjects who entered the school at 2004 - 0.32(2004), 0.25(2005), 0.25(2006) and 0.38(2007), (2)the subjects who entered the school at 2005 - 0.18(2005), 0.31(2006) and 0.32(2007), and (3)the subjects who entered the school at 2006 - 0.19(2006) and 0.27(2007). Conclusions: This study partially showed the effects of school-based oral health programs on the increments of dental caries. This programs should be expanded widely among elementary schools in Korea.