• 제목/요약/키워드: preventive effects

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한인진(韓茵蔯)이 알콜 투여로 유발된 흰쥐의 고지혈증과 간 손상의 예방에 미치는 영향 (Preventive effects of water extracts from Artemisiae Iwayomogi Herba on hyperlipiderma and liver damage induced by alcohol)

  • 서부일
    • 대한본초학회지
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    • 제22권1호
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    • pp.103-110
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    • 2007
  • Objectives : This study was performed to prove the preventive effect of water extracts from Artemisiae Iwayomogi Herba on hyperlipiderma and liver damage induced alcohol. Methods : Except for the normal group, we fed rat on 25% alcohol for 55 days. And Artemisiae Iwayomogi Herba extract was administrated for the same period. We measured the serum component in rat's blood. body weight and weight of liver. Result : At first, we observed preventive effects of Artemisiae Iwayomogi Herba on hyperlipiderma induced by alcohol. Artemisiae Iwayomogi Herba group showed significant decrease of total cholesterol and triglyceride in comparison with those of the control group. Artemisiae Iwayomogi Herba group showed significant increase of body weight in comparison with those of the control group in 4weeks and 8weeks. At second, we observed preventive effects of Artemisiae Iwayomogi Herba on liver damage induced by alcohol. Artemisiae Iwayomogi Herba group showed significant decrease of GOT, ALP and LDH in comparison with those of the control group. Artemisiae Iwayomogi Herba group showed significant increase of liver weight in comparison with those of the control group. Conclusion : Reviewing these experimental results, it appears that water extracts from Artemisiae Iwayomogi Herba have pharmaceutical preventive efficacy on hyperlipiderma and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of Artemisiae Iwayomogi Herba.

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한약이 실험동물의 태자에 미치는 생식독성학적 영향 -오적산을 중심으로- (Herbal Toxicological Effects on Rats' Fetus -Focusing on Ojeoksan-)

  • 박해모;신헌태;이선동
    • 대한예방한의학회지
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    • 제12권2호
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    • pp.27-35
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    • 2008
  • Purpose : The experiments was undertaken to evaluate the effects of Ojeoksan-herbal medicine, in rats' fetus Methods : Female Sprague-Dawley rats were orally administered with the Ojeoksan at dose of 5mg/kg/day for 20 days. Pregnant rats were sacrificed at 20th day of gestation, and observed internal and reproductive organs. Approximately live fetuses in the 20th day of gestation were randomly selected and fixed in 95% ethanol. Results : Neonatal body weight and number of fetus of Ojeoksan group were increased to that of control group. The fetuses of dams treated with Ojeoksan didn't showed external malformation. Vertebral and sternal skeletal variations were observed in Ojeoksan administered group, but compared to the control, those skeletal variations were insignificant. There were no significant changes in number of ribs, cervical, thoracic, lumber, sacral and caudal Conclusion : From these results, it can be concluded that Ojeoksan showed no toxicity effects on number of live fetuses. There were no significant changes in skeletal variations were showed in vertebrate and sternum, Ojeoksan weren't shown significant changes in bone malformation. We need more precise study to investigate the mechanism of early or late resorption by the herbal medicines such as Ojeoksan.

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허베이 스피릿호 유류유출사고 지역 산모의 BTEX 노출과 건강영향 (BTEX Exposure and its Health Effects in Pregnant Women Following the Hebei Spirit Oil Spill)

  • 김병미;박은교;이안소영;하미나;김은정;권호장;홍윤철;정우철;허종일;정해관;이종협;김종호;이보은;서주희;장문희;하은희
    • Journal of Preventive Medicine and Public Health
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    • 제42권2호
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    • pp.96-103
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    • 2009
  • Objectives : We evaluated the health effects of exposure to BTEX(Benzene, Toluene, Ethylbenzene, m,p-Xylene, o-Xylene) in the Taean area after the Hebei Spirit oil spill. Methods : We used a questionnaire survey to look for health effects among 80 pregnant women 2 to 3 months following the Hebei Spirit oil spill. Their BTEX exposures were estimated using the CALPUFF method. We then used a multiple logistic regression analysis to evaluate the effects of BTEX exposure on the women s health effets. Results : Pregnant women who lived near the accident site reported more symptoms of eye irritation and headache than those who lived farther from the site. There was a trend of decreasing symptoms with an increase in distance from the spill site. Pregnant women exposed to higher ambient cumulative levels of Xylene were significantly more likely to report symptoms of the skin(OR 8.01 95% CI=1.74-36.76) in the first day after the accident and significantly more likely to report abdominal pain(OR 3.86 95% CI=1.02-14.59 for Ethylbenzene, OR 6.70 95% CI=1.82-24.62 for Xylene) during the 1st through 4th days following the accident. Conclusions : This study suggests that exposure to BTEX from an oil spill is correlated with an increased risk of health effects among pregnant women. This implies the need to take proper measures, including the development of a national policy for environmental health emergencies and a plan for studying the short- and long-term chronic health effects associated with such spills.

위험인식태도와 불안이 미세먼지 예방행동의도에 미치는 영향: RPA모델 적용을 중심으로 (Effects on Preventive Behavior Intention to Particulate Matter by Risk Perception Attitude and Anxiety : Focus on Adoption of RPA Model)

  • 고두희;송해룡
    • 디지털융복합연구
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    • 제18권10호
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    • pp.517-526
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    • 2020
  • 본 연구는 미세먼지에 대한 위험인식태도와 불안이 미세먼지 예방행동의도에 미치는 영향을 확인하는 것을 목적으로 했다. 또한, 위험인식태도모델(RPA)의 적용대상과 범위를 확장하기 위해서 불안 변인을 추가하였다. 570명의 대학생을 대상으로 진행한 설문조사를 진행하였으며, 수집된 자료를 바탕으로 상관관계분석 및 일원배치분산분석, 삼원변량분석을 진행하였다. 분석 결과, 미세먼지에 대한 지각된 위험과 효능감이 예방행동의도와 정보추구의도에 통계적으로 유의미 한 것으로 나타났다. 불안도 예방행동의도와 정보추구에 유의미하게 영향을 주는 것으로 나타났다. RPA 모델의4 태도집단으로 구분하여 분석한 결과, 각 집단별로 예방행동의도와 정보추구의도에서 유의미한 차이를 보였으며, 불안요인이 일부 태도집단에 유의미한 영향을 주는 것으로 나타났다. 본 연구결과는 미세먼지 예방캠페인에서 태도집단에 맞는 메시지의 계획과 실행이 필요함을 시사한다. 후속 연구에서 사회심리학 변인 등의 영향을 고려한다면, 미세먼지 관련 건강행동을 파악하는데 도움이 될 것이다.

환자-교차 대조군 연구를 적용한 산업재해 발생의 단기적 영향 요인 (Transient Effects the Risk of Occupational Injuries as an Acute Events : a Case-crossover Study)

  • 정선아;원종욱;노재훈;이종태
    • Journal of Preventive Medicine and Public Health
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    • 제34권1호
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    • pp.35-40
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    • 2001
  • Objectives : To elucidate the transient effects on the risk of occupational injuries as acute events and establish so alternative proposal. Methods : The study population comprised a total of 302 workers randomly selected from applications for occupational injury compensation reported to the Inchon local labor office from January 1. 1999 to December 31. A case-crossover design, where each case serves its own control, was applied to this study. Through a telephone interview, workers provided useful data concerning five job related stressful events such as company transfer, work load change, overtime work, exchange duty, and work-part transfer. They were asked whether there were stressful events within a week of the occurrence of injury and the degree of stress. Exposure status from one year prior was used as control information. In the end, the data provided by 158 of selected persons was used for the analysis based on the quality of the data provided by the participants. A conditional logistic regression was used to discover the transient effects on the risk of occupational injuries as acute events. Results : The effects a company transfer and work load change on occupational injury was statistically significant on the risk of occupational Injuries as an acute event(RR=5.5, 95% CI=2.501-12.428; RR=3.1, 95% CI=1.963-5.017, respectively). Other stressful events were found to elevate the risk factor for the occurrence of occupational jujury, but were not significant. Conclusions : Our results suggested that transient stressful events elevated the risk factor for the occurrence of occupational injury.

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장애인의 건강관심도, 건강실천행위 그리고 건강수준간의 구조분석 (Structural Relationships among Health Concern, Health Practice and Health Status of the Disabled)

  • 천병렬;감신;예민해;강윤식;김건엽;손재희;이영숙;박기수
    • Journal of Preventive Medicine and Public Health
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    • 제32권3호
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    • pp.276-288
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    • 1999
  • Objectives: This study was performed to determine the relationships among health concern, health practice and health status of the disabled. Methods: A self-administered questionnaire survey was carried out for 1,662 disabled persons in Taegu city from April to July, 1997. Results: Health concern had a significant and positive relationship with health practice(p<0.05) and health practice also had a significant and positive relationship with self-rated health status(p<0.05) in men and women. To determine the structural model of the Health concern, health practice, health status and sociodemographic variables, the covariance structural analysis was used. In men, age, economic status, medical security type, educational level and type of disability had significant direct effects on Health concern(T>2.0). Educational level and type of disability had significant direct effects on health practice(T>2.0). And Economic status, medical security type and job status had significant direct effects on health status(T>2.0). In women, economic status and educational level had significant direct effects on Health concern(T>2.0). However there was no variable which had a significant direct effect on health practice. Job status had a significant direct effect or health status(T>2.0). In men and women, health practice was significantly increased with increasing health concern and the more health practice, the higher health status(T>2.0). Conclusions: It is recommended that the institutional approach which improve the economic status of the disabled with understanding their behavior and attitude should be established to increase health status, in addition, the health policy for encouraging the disabled, such as health education, consulting and health promotion program, should be done.

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