• 제목/요약/키워드: preventive effects

검색결과 2,605건 처리시간 0.047초

난알부민 유도 알레르기 비염 마우스에 대한 소청룡탕(小靑龍湯)의 효능 실험연구 (Anti-allergic effects of So-Cheong-Ryong-Tang in ovalbumin-induced allergic rhinitis model)

  • 김일환;구진모;허한솔;나창혁;장보형;신용철;고성규
    • 대한예방한의학회지
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    • 제18권3호
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    • pp.69-80
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    • 2014

  • Objective : Allergic rhinitis (AR) is an allergic inflammation of the nasal airways. Socheongryong-Tang traditionally has been used in Korea for treatment of allergy diseases. In the present study, we investigated whether SCRT suppresses the progression of AR in vivo and in vitro. Method : In this study, we investigated the effect of oral administration of SCRT on the Ovalbumin(OVA)-induced allergic rhinitis mouse models. Additionally, to find a possible explanation for the anti-inflammation effects of SCRT, we evaluated the inflammatory cytokine levels in LPS-stimulated mouse inflammation cell (RAW264.7) and mouse splenocyte. Results : The finding of this study demonstrated that SCRT reduced mast cells and inflammation cells infiltration in OVA-induced nasal cavity. Additionally, SCRT inhibited the production of inflammatory cytokines in splenocyte. However SCRT don't inhibited the production of inflammatory cytokines in RAW264.7 cells. Conclusion : Taken together, our results showed that oral administration of SCRT beneficial effects in allergic rhinitis, suggesting that SCRT might be a useful candidate for the treatment of allergic rhinitis.

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황사 기간 동안에 어린이, 성인, 노인에서의 자각증상과 예방행동에 대한 조사연구 (Study on Perceived Symptoms and Preventive Behaviors during Asian Dust storms among Children, Adults and Elders)

  • 이보은;하은희;박혜숙;권지숙;신경림
    • 한국학교보건학회지
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    • 제18권1호
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    • pp.15-25
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    • 2005

  • Purpose: Recently there are scientific evidences for the health effects of Asian dust-storms. Particularly in 2002, the daily average of $PM_10$ exceeded 600 and 700 $\mu{g}/m^3$ in March and April respectively. We examined the effects of Asian dust‐storms on perceived symptoms and preventive behaviors among children, adults, and elders. Method: The subjects of this study were 425 children, 444 adults and 60 elders. A questionnaire survey was carried out on the children and the adults by teachers and on the elders by interviewers to obtain information on demographic variables, perceived symptoms and preventive behaviors, previous respiratory disease, environmental tobacco smoke, and proximity between the house and the road during Asian dust-storms. We analyzed using descriptive statistics, $X^2$ test and multiple logistic regression models. After adjustment for potential confounders, we estimated the odds ratios and 95% confidence intervals of the children and the elders for perceived symptoms and preventive behaviors. Result: The elders had a significantly higher prevalence of respiratory symptoms than the other groups. The children had a significantly higher prevalence than the adults in getting URI (1.51), coughing (1.68), rhinorrhea (1.46), fever (2.39) and medication for allergy or asthma (1.90). The children had better behaviors than the elders in closing windows (3.57), taking less outdoor recreational activity (2.59) and staying home (2.60). Conclusion: This study suggested that children and elders are susceptible to the effects of Asian dust on health. Health educators should inform these populations about the influence of Asian dust and provide health education for preventive behaviors.

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