• Clinical and Experimental Pediatrics
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• v.63 no.8
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• pp.291-300
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• 2020

Advances in autoimmune encephalitis studies in the past 10 years have led to the identification of new syndromes and biomarkers that have transformed the diagnostic approach to the disorder. The disorder or syndrome has been linked to a wide variety of pathologic processes associated with the neuron-specific autoantibodies targeting intracellular and plasma membrane antigens. However, current criteria for autoimmune encephalitis are quite dependent on antibody testing and responses to immunotherapy, which might delay the diagnosis. This form of encephalitis can involve the multifaceted presentation of seizures and unexpected behavioral changes. The spectrum of neuropsychiatric symptoms in children is less definitive than that in adults, and the incorporation of clinical, immunological, electrophysiological, and neuroradiological results is critical to the diagnostic approach. In this review, we document the clinical and immunologic characteristics of autoimmune encephalitis known to date, with the goal of helping clinicians in differential diagnosis and to provide prompt and effective treatment.

• Clinical and Experimental Pediatrics
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• v.45 no.10
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• pp.1278-1282
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• 2002

Glutaric aciduria(type 1) is characterized clinically by progressive dystonia and dyskinesia in childhood, pathologically by degeneration of caudate and putamen, biochemically by tissue deficiency of glutaryl-CoA dehydrogenase(GCDH), and is transmitted as an autosomal recessive traits. Mutations of the GCDH gene on chromosome 19 have been implicated in the causation of glutaric aciduria(type 1). Macrocephaly in infancy and crossing of percentiles for head circumference are real clues to early diagnosis. Acute neuroregression of dystonia following an initial phase of normal or almost normal development is a common mode of presentation, at times preceded by seizures. We experienced a case of glutaric aciduria(type 1) in a 13-month old girl. She was admitted due to development delay and choreoasthetoid movememt that developed after generalized tonic-clonic type seizures. She was diagnosed as having glutaric aciduria(type 1) based on brain MRI and urine organic acid analysis finding.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.1
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• pp.70.4-71
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• 2016

The links between super-massive black hole masses and their host galaxy properties are observed, indicating that black hole growth and host galaxy evolution are closely related. Reverberation mapping, which uses the time delay from the central black hole to broad line regions, is one of the best methods to estimate masses of black holes of active galactic nuclei (AGNs). However, only masses of about 50 black holes have been determined in reverberation mapping studies so far, and most of them are limited to optical luminosities below 10^45 erg/s due to the challenges of long-term time domain observations in both photometry and spectroscopy. In this project, we expand reverberation mapping samples to higher luminosities of > 10^44.5 erg/s at 0.1 < z < 0.35, that have expected time lags of 40 - 250 light days. Photometric (using LOAO 1-m and MDM 1.3-m) and spectroscopic (using MDM 2.4-m and Lick 3-m) monitoring campaigns are being conducted for a 3 year duration and 20 day cadence. Precedent photometric observations in 2015B show some targets with variability and follow-up spectroscopic observations are on-going. In this presentation, we introduce our project, present reverberation mapping simulation results, and preliminary results on photometry. These reverberation mapping masses of relatively high luminous AGNs will provide a strong constraint on black hole mass calibration, e.g., the single-epoch mass estimation.

• The Transactions of the Korea Information Processing Society
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• v.3 no.6
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• pp.1386-1396
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• 1996

In the distributed multimedia application, high throughput and low delay is one of the most important QoS(Quality of Service) requirement. Emerging high speed communication offers transmission rate above Gbps, but it can not be utilized efficiently by the performance bottlenecks of communication protocols. To overcom the problem, we propose a horizontal processing architecture that processes data as soon as it arrive from the network. Unfortunately, the OSI protocol stack often imposes ordering constraints that prevent concurrent processing of the protocol layers. By using a fixed packet format, the network layer through the presentation layer are processed in parallel. Our prototype shows that the proposed model has performance improvement up to 61% more advantage than the conventional approach.

• The KIPS Transactions:PartC
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• v.9C no.6
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• pp.953-960
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• 2002

Rel-time application programs have constraints which need to be met between media-data. It is client-leading synchronization that is absorbing variable transmission delay time and that is synchronizing by feedback control and palyout control. It is the important factor for playback rate and QoS if the buffer level is normal or not. This paper, The method of maintenance buffer normal state transmits in multimedia server by appling feedback of filtering function. And synchronization method is processing adaptive playout time for smooth presentation without cut-off while media frame is skip. When audio frame which is master media is in upper threshold buffer level we decrease play out time gradually, low threshold buffer level increase it slowly.

• Journal of Broadcast Engineering
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• v.11 no.3 s.32
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• pp.363-378
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• 2006

The Digital Multimedia Broadcasting(DMB) system is developed to offer high quality audio-visual multimedia contents to the mobile environment. The system adopts MPEG-4 standard for the main video, audio and other media format. It also adopts the MPEG-4 scene description for interactive multimedia contents. The animated and interactive contents can be actualized by BIFS(Binary Format for Scene), the binary format for scene description that refers to the spatio-temporal specifications and behaviors of the individual objects. As more interactive contents are, the scene description is also needed more high bitrate. However, the bandwidth for allocating meta data such as scene description is restrictive in mobile environment. On one hand, the DMB terminal starts demultiplexing content and decodes individual media by its own decoder. After decoding each media, rendering module presents each media stream according to the scene description. Thus the BIFS stream corresponding to the scene description should be decoded and parsed in advance of presenting media data. With these reason, the transmission delay of BIFS stream causes the delay of whole audio-visual scene presentation although the audio or video streams are encoded in very low bitrate. This paper presents the effective optimization technique for adapting BIFS stream into expected MPEG-2 TS bitrate without any bandwidth waste and avoiding the transmission delay of the initial scene description for interactive DMB contents.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5349-5357
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• 2015

Background: Breast cancer is the most common cancer and the leading cause of cancer mortality among women of all ethnic and age groups in Malaysia. Delay in seeking help for breast cancer symptoms is preventable and by identifying possible factors for delayed diagnosis, patient prognosis and survival rates could be improved. Objectives: This narrative review aimed to understand and evaluate the level of in-depth breast cancer knowledge in terms of clinical breast examination and breast self-examination, and other important aspects such as side-effects and risk factors in Malaysian females. Since Malaysia is multicultural, this review assessed social perceptions, cultural beliefs and help-seeking behaviour in respect to breast cancer among different ethnic groups, since these may impinge on efforts to 'avoid' the disease. Materials and Methods: A comprehensive literature search of seven databases was performed from December 2015 to January 2015. Screening of relevant published journals was also undertaken to identify available information related to the knowledge, perception and help-seeking behaviour of Malaysian women in relation to breast cancer. Results: A total of 42 articles were appraised and included in this review. Generally, women in Malaysia had good awareness of breast cancer and its screening tools, particularly breast self-examination, but only superficial in-depth knowledge about the disease. Women in rural areas had lower levels of knowledge than those in urban areas. It was also shown that books, magazines, brochures and television were among the most common sources of breast cancer information. Delay in presentation was attributed mainly to a negative social perception of the disease, poverty, cultural and religion practices, and a strong influence of complementary and alternative medicine, rather than a lack of knowledge. Conclusions: This review highlighted the need for an intensive and in-depth breast cancer education campaigns using media and community health programmes, even with the existing good awareness of breast cancer. This is essential in order to avoid misconceptions and to frame the correct mind-set about breast cancer among women in Malaysia. Socio-cultural differences and religious practices should be taken into account by health care professionals when advising on breast cancer. Women need to be aware of the risk factors and symptoms of breast cancer so that early diagnosis can take place and the chances of survival improved.

• Journal of KIISE:Computing Practices and Letters
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• v.9 no.6
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• pp.623-634
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• 2003

In this paper, we propose a collaborative multimedia authoring system. Our authoring system represents a multimedia presentation in a 3D coordinate system. One axis represents the traditional timeline information (T-zone), and the other two axes represent spatial coordinates (XY-zone). Our system represents a visual media objects as a 3D parallelepipeds and audio media objects as cylinders. This interface allows for simultaneous authoring and manipulation of both the temporal and the spatial aspects of a presentation. Using our system, users can design multimedia presentations collaboratively in the unified spatio-temporal space while freely traversing the spatial domain and the temporal domain without changing the context of authoring. In addition, we suggest an efficient mechanism of concurrency control for shared objects generated by our collaborative writing system. The mechanism is mainly based on the user awareness, the multiple versions, and the access permission of shared objects. Our concurrency control mechanism is designed to keep data consistency by minimizing the collision due to the delay or the failure of network communication and to allow maximum responsiveness for users using optimistic concurrency control. Also, the mechanism maximize the responsiveness by refining the locking granularity and applying different concurrency control mechanisms to each.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.19
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• pp.8135-8142
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• 2014

Background: Breast cancer is the most common cancer in Iranian women and usually features delayed presentation and late diagnosis. Interpretation of symptoms, as the most important step, has a significant impact on patient delay in seeking treatment. There is a dearth of studies on symptom appraisal and the process leading to seeking help in breast cancer patients. This study explored the perceptions and experiences of Iranian women with self-detected possible breast cancer symptoms. Materials and Methods: A qualitative method was conducted involving in-depth semi-structured interviews with 27 Iranian women with self-discovered breast cancer symptoms. Participants were purposefully selected from women who attended Cancer Institute of Tehran University of Medical Sciences during June 2012 to August 2013. The audiotaped interviews were transcribed and analyzed using conventional content analysis with MAXQDA soft ware version 10. The trustworthiness of the study was verified by prolonged engagement, member validation of codes, and thick description. Results: The main concepts emerging from data analysis were categorized in four categories: symptom recognition, labeling of symptoms, interactive understanding, and confronting the fear of cancer. Symptom recognition through breast self-examination, symptom monitoring and employing prior knowledge distinguished normal from abnormal symptoms and accompanied with perception of being at risk of breast cancer led to symptom labeling. Social interaction by selective disclosure and receiving reassurance from a consultant led to confirmation or redefinition of the situation. Perceived seriousness of the situation and social meanings of breast cancer as a stigmatized and incurable illness associated with loss of femininity were reasons for patient worries and fear. Conclusions: This study emphasized that entangled cognitive, emotional and socio-cultural responses affecting understanding of symptom seriousness require further investigation. It is suggested that programs aimed at shortening patient delay in breast cancer should be focused on improving women's knowledge and self-awareness of breast cancer, in addition to correcting their social beliefs.

• Korean Journal of Cognitive Science
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• v.11 no.3_4
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• pp.83-93
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• 2000

The effect of immediate and delayed recognition memory on event-related potential (ERP) was studied using a continuous recognition memory task and event-related potential (ERP). Among 240 stimulus words 40 words were not repeated. 100 were immediately repeated and 100 were repeated after 5 intervening words. All words presented only once during the experiment were referred to as new words. Subjects responded faster and more accurately to words repeated immediately than to new words a and to those repeated after intervening words. In terms of ERP results the immediately repeated words were associated with large P300 amplitude, early P300 latency and a absence of N400. while words repeated after a delay were associated with small P300 a amplitude. late P300 latency and the presence of N400. N400 was elicited only to new w words and to those repeated after a delay. The general morphology of the waveform was s similar for three stimulus-presentation conditions until around 3l0ms after the onset of stimulus. These results indicate that immediate and delayed recognition memory could be dissociated into two distinct processes possibly being mediated by different cerebral mechanism, and the dissociation between two types of recognition memory emerges around 3l0ms poststim'ulus. The immediate and delayed recognition memory for words are considered in terms of template matching and memory searching.