• The Korean Journal of Archival Studies
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• no.61
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• pp.157-190
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• 2019

The Records Appraisal Review contains the processes and results of appraisal works for records. This study is an analysis of the 2018 Records Appraisal Review of 22 Local Education Offices where records managers were deployed. To ensure reliability of analyzing results, the analysis data preparation criteria were applied to maintain consistency in the analysis data preparation. Also, statistics by appraisal process and retention period were cross-checked. Through the analysis of the Records Appraisal Review identifies the actual condition for records appraisal. Based on this, the improvement measures that are applicable in practice were proposed in terms of records management of department, appraisal works of records manager and operation of Records Appraisal Review Commission.

• Journal of the Korean Academy of Esthetic Dentistry
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• v.29 no.1
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• pp.25-34
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• 2020

In recent years, as a burden on tooth preparationduring the processing the laminate veneer treatments to enhance aesthetics, the interests and demands for non-prep laminate veneers are increasing which do not require teeth preparation. Although there are clear limitationsbecause the restorations are fabricated without tooth preparation, there is a clear advantage of non-invasivehealthy teeth. When manufacturing a non-prep laminate veneer, an effective design should be selected according to the aesthetic requirements and intraoral condition because the margin of restorationsshould be determined on the natural tooth surface that isnot prepared. In this article, I would like to presentthe three different designsaccording to the range which teeth are covered, and the advantages and disadvantages of them. Non-prep laminate veneer introduced in this article was fabricated using Lithium disilicate press ingot.

• The Korean Journal of Physiology
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• v.1 no.1
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• pp.67-72
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• 1967

Present paper is attempted to introduce the phenomenon of 'after contraction' in isolated cardiac-muscle. Papillary muscles were removed from cat right ventricle and were used as a preparation. The muscle strip was Placed in tissue bath which is kept in steady temperature of around $25^{\circ}C$ and was perfuced by Tyrode solution, saturated with 95% $O_2$ and 5% $CO_2.$ under the condition of high calcium (8.2-10.0 mM/l), low sodium (72.4-70.0 mM/l) perfusion with the administration of epinephrine (1-2 mg/l) into tile tissue bath normally triggered muscle contraction was followed by oscillatory, repetitive contractions - after contraction. The phenomenon of after contraction was augumented by decrease in tissue bath temperature and by increase in number of preceding beats and in driving rate. Authors were able to maintain the phenomenon in prominent and steady state giving proper experimental conditions such as fixed bath temperature (ranged from $22^{\circ}C\;to\;27^{\circ}C$), suitable driving rate (20 per minute in average) and perfusion of high calcium, loll sodium and 1-2 mg/l of epinephrine. In some preparations, the strength of after contraction (second contraction) reached up-to 80% of normally triggered contraction and five repetitive contractions were observed as largest number of after contractions. Intracellular action potential measured in the muscle which was beating regulary showing steady after contraction revealed no oscillating after potential in most parts of the muscle but in few cases oscillating changes of after potentials were detectable. In electrogram of the muscle preparation recorded by means of contact electrode prominent, oscillating after potentials were observable when the recorder was set at highest sensitivity. It still is not clear that whether after contraction is the phenomenon which corresponds to those changes in action potential, oscillating after potential, of the muscle preparation. Possible mechanism of the phenomenon of after contraction relating with after potential changes was proposed. Detailed results obtained from further studies on after contraction and concrete discussion on the phenomenon will be reported by authors.

• Journal of Pharmaceutical Investigation
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• v.25 no.1
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• pp.31-36
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• 1995

Solid dispersions and inclusion complex were prepared for the enhancement of solubility and dissolution rate of poorly water-soluble ibuprofen(IPF) as a model drug. Polyethylene glycol 4000(PEG4000) and polyvinylpyrrolidone(PVP) were used for the preparation of solid dispersion. $2-Hydroxypropyl-{\beta}-cyclodextrin(2-HP{\beta}CD)$ was also used for the preparation of inclusion complex. The solubility of IPF increased as the concentration of PEG4000, PVP and $2-HP{\beta}CD$ increased. Solubilization capacity of $2-HP{\beta}CD$ was increased about 10 times when compared to PEG 4000 and PVP. The dissolution rate of drug from solid dispersions and inclusion complex in the simulated gastric fluid was enhanced when compared to pure IPF and commercial $BR4^{\circledR}$ tablet as a result of improvement of solubility. In case of solid dispersions, dissolution rate of drug was proportional to polymer concentration in the formulation. The marked enhancement of dissolution rate of drug by inclusion complexation with $2-HP{\beta}CD$ was noted. However, dissolution rate of drug from solid dispersions and inclusion complex in the simulated intestinal fluid was not significant because IPF was readily soluble in that condition. From these findings, water-soluble polymers and cyclodextrin were useful to improve solubility and dissolution rate of poorly water-soluble drugs. However, easiness and reliability of preparation method, scale-up and cost of raw materials must be considered for the practical application of solid dispersion and inclusion complex in pharmaceutical industry.

• KSBB Journal
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• v.32 no.2
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• pp.108-116
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• 2017

Omeprazole, a benzimidazole derivative, suppresses gastric acid secretion by inhibiting $H^+/K^+$ ATPase in gastric parietals cells, and by reducing $H^+$ concentration. To improve stability of esomeprazole magnesium dihydrate (ESMD), enteric-coated preperation was composed of core tablet, subcoating and enteric coating layer. We were evaluated in vitro dissolution characteristics between test and reference ESMD preparation and stability. We could prepare enteric-coated formulation of ESMD by controlling disintegrating agent and coating ratio which could rapidly dissolved in neutral or alkali medium. The formulation D5 with crospovidone of 1.25% and coating ratio of 16.25% had a similar dissolution behavior compare to reference preparation. Difference factor ($f_1$) and similarity factor ($f_2$) were 0~15 and 50~100 and there was no significant difference in bioequivalence between formulations. The content and dissolution rate of formulation D5 were $96.54{\pm}0.21$ and $78.56{\pm}0.87%$ without change of color in accelerated condition ($40^{\circ}C$, RH 75%, high density polyethylene (HDPE) container) for 6 months. This study concluded that our enteric coated preparation of ESMD could be an useful method to improve stability of unstable drug without direct contact with coating material.

• Fisheries and Aquatic Sciences
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• v.3 no.3_4
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• pp.200-204
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• 2000

To investigate pre-salting conditions in the preparation of salted anchovy from large anchovy, anchovy were salted with various salt concentration and stored at $5^{\circ}C$ and $20^{\circ}C$ for 10 days. Moisture content decreased with the increase of salt and the salinity increased in proportion to salt concentration at $20^{\circ}C$. Total nitrogen decreased slightly as the increase of salt concentration during pre-salting at $20^{\circ}C$. The nitrogenous components such as amino nitrogen and extractable nitrogen were invariable or decreased until 7 days in salt concentration over $25\%$ during pre-salting at $5^{\circ}C$. These results imply that soluble nitrogen with moisture run out of anchovy body in high salt concentration and the hydrolysis was inhibited by salt over $25\%$ at $5^{\circ}C$. VBN content were constant in salt concentration over $25\%$ until 7 days, regardless of curing temperature. The POV were under the influence of salt concentration and temperatures. We concluded that the optimal condition for preparation of salted anchovy were pre-salting with salt over $25\%$ at $5^{\circ}C$ for 7 days.

• Resources Recycling
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• v.17 no.4
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• pp.30-36
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• 2008

The preparation of porous lightweight materials as well as the measurement of physical properties has been performed by using SSA(sewage sludge ash) as the raw material. For this aim, two types of lightweight filler, that is, perlite and silica sphere were employed respectively and bentonite was also used as an inorganic binder. The properties of lightweight specimen calcined at 1,000 were measured in terms of density, compressive strength, thermal conductivity and sound absorption to examine the effect of material composition as well as the preparation condition on the properties of lightweight material. As a result, the density of specimen prepared with perlite was ranged from 1.23 to $1.37g/cm^3$ and the compressive strength was ranged from 242.3 to $370.5kg/cm^2$. In case of specimen prepared with silica sphere, it was found that the compressive strength was less than $100kg/cm^2$ even though density was lower than that of specimen with perlite. As far as the thermal conductivity of specimen was concerned, it was ranged from 0.3 to $0.5W/m^{\circ}K$ depending on material composition so that the insulation effect was superior to conventional concrete.

• Food Science and Biotechnology
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• v.18 no.5
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• pp.1230-1236
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• 2009

Optimum conditions for the freeze-thaw stability (FTS) of mung bean starch (MBS) paste as a main ingredient in omija-eui were investigated. For the optimization of the paste preparation condition, the FTS of MBS prepared by boiling in a shaking water bath (BMSW) or by pressure-cooking in an autoclave (PCMA) were analyzed using a response surface methodology (RSM). In addition, the effects of various additives such as gums, sugars, and emulsifier were evaluated on the FTS of MBS paste prepared under optimal conditions. The predicted maximal FTS of MBS paste prepared by the PCMA method (73%) was higher than that of the paste prepared by the BMSW method (36%). In case of additives, gellan gum and sodium alginate effectively prevented the syneresis of MBS paste in the BMSW method and in the PCMA method, respectively. The use of a fructose fatty acid ester as an emulsifier decreased syneresis in a dose-dependent, while the addition of sugars accelerated syneresis. Consequently, MBS paste for omija-eui preparation may be efficiently prepared by adding sodium alginate and fructose fatty acid ester under the optimal conditions of 4.3% MBS content, $121^{\circ}C$ heating temperature, and $89^{\circ}C$ cooling temperature by pressure-cooking in an autoclave.

• The Journal of the Korea Contents Association
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• v.16 no.12
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• pp.480-491
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• 2016

This study aims to determine the factors associated with preparation for turnover in youth employees, using a data from the Youth Panel 2007-2013. Study population were composed by 17,037 employees and a generalized estimating equations (GEE) using panel logit model was performed. It was identified that socioeconomic(age, sex, level of education, monthly income and type of employment) and work-related factors(perception of difficulties in performing tasks compared to level of education, perception on the Job-Major match, stabilization of employment, autonomy and empowerment of jobs, peer relationship in workplace) were statistically significant variables. Based on the analysis, dissatisfaction on working environment or condition might lead to employees prepare to turnover and it is a series of activities that to improve welfare and find a suitable job for oneself.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.41 no.2
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• pp.105-112
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• 2015

Resveratrol is a natural polyphenol. It protects skin from skin injury, ultraviolet radiation and pathogenic attack. This study is to find the optimum condition for the preparation of ethosome loading amount of resveratrol in ethosome. Ethosomes were prepared by modified hydrated liquid crystal method. Investigation of factors affecting the entrapment efficiency and particle size of ethosomes was carried out. The particle size of ethosome were measured by particle analyzer. The loading efficiency of resveratrol in ethosome was measured by HPLC. The particle sizes were 111.2 ~ 112.8 nm and the loading efficiency of resveratrol was 81.25 ~ 88.75%. The optimum conditions for the preparation of ethosome was obtained from of lecithin : resveratrol : cholesterol : ethanol at a weight ratio of 2.0 : 0.08 : 0.05 : 20.0.