• Title/Summary/Keyword: ppd

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Change of IFN-$\gamma$ and TNF-$\alpha$ Producing Capacity in the Course of Chemotherapy in Patients with Pulmonary Tuberculosis (폐결핵환자의 치료 시점에 따른 말초혈액 단핵구의 IFN-$\gamma$, TNF-$\alpha$ 분비능의 변화)

  • Yim, Jae-Joon;Lee, Sang-Min;Lee, Jae-Ho;Yoo, Chul-Gyu;Lee, Choon-Taek;Chung, Hee-Soon;Kim, Young-Whan;Han, Sung-Koo;Shim, Young-Soo
    • Tuberculosis and Respiratory Diseases
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    • v.48 no.2
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    • pp.149-154
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    • 2000
  • Background: Interleron-gamma(IFN-$\gamma$) and tumor necrosis factor-alpha(TNF-$\alpha$) playa critical role in protective immunity against Mycobacterium tuberculosis infection The change of IFN-$\gamma$ and TNF -$\alpha$ producing capacity in the course of antituberculous chemotherapy in patients with pulmonary tuberculosis was evaluated in this study. Method: In 29 patients with pulmonary tuberculosis, phytohemagglutinin(PHA) or purified protein derivative(PPD) stimulated production of IFN-$\gamma$ and TNF-$\alpha$ by peripheral blood mononuclear cells was quantified. Five patients were sampled before they underwent antituberculous treatment, 11 patients after 0-4 months, six after 4-completion and seven after treatment completion. Result: There was no difference in PHA- or PPD-stimulated production of IFN-$\gamma$ and TNF-$\alpha$ between each group. Conclusion: No difference in PHA- or PPD- stimulated production of IFN-$\gamma$ and TNF-$\alpha$ between two groups could be identified according to their treatment with pulmonary tuberculosis.

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A Study on the Synthesis of p-phenylenediamine (PPD) Using Copper Catalyst (Copper 촉매를 이용한 p-phenylenediamine (PPD) 합성에 관한 연구)

  • Kim, Jungsuk;Lee, Sang-yong;Lee, Jungho;Choi, Won Choon;Kang, Na Young;Park, Sunyoung;Kim, Kiwoong;Lim, Jong Sung;Park, Yong-Ki;Seo, Hwimin
    • Korean Chemical Engineering Research
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    • v.54 no.3
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    • pp.425-430
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    • 2016
  • p-Phenylenediamine (PPD) was synthesized by aromatic amination of p-diiodobenzene (PDIB) using liquid ammonia and Cu-catalysts. The effects of the catalyst, reductant, ammonia quantity and reaction temperature on PPD production were investigated. Cu(I) compounds and Cu powder were selected as catalyst due to a higher selectivity than Cu(II) compounds. As the catalyst quantity increased, rate of PPD production as well as side reaction of aniline decreased with increasing the quantity of ammonia. Reductants such as ascorbic acid, hydrazine and dihydroxyfumaric acid were tested to lower the catalyst loading. The use of reductants resulted in increasing the reaction rate but also increased the amount of aniline The rate of reaction using ascorbic acid or dihydroxyfumaric acid was faster than that using hydrazine. The lowest side reaction of aniline was found in dihydroxyfumaric acid of reductants investigated.

Variation of probability of sonar detection by internal waves in the South Western Sea of Jeju Island (제주 서남부해역에서 내부파에 의한 소나 탐지확률 변화)

  • An, Sangkyum;Park, Jungyong;Choo, Youngmin;Seong, Woojae
    • The Journal of the Acoustical Society of Korea
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    • v.37 no.1
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    • pp.31-38
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    • 2018
  • Based on the measured data in the south western sea of Jeju Island during the SAVEX15(Shallow Water Acoustic Variability EXperiment 2015), the effect of internal waves on the PPD (Predictive Probability of Detection) of a sonar system was analyzed. The southern west sea of Jeju Island has complex flows due to internal waves and USC (Underwater Sound Channel). In this paper, sonar performance is predicted by probabilistic approach. The LFM (Linear Frequency Modulation) and MLS (Maximum Length Sequence) signals of 11 kHz - 31 kHz band of SAVEX15 data were processed to calculate the TL (Transmission Loss) and NL (Noise Level) at a distance of approximately 2.8 km from the source and the receiver. The PDF (Probability Density Function) of TL and NL is convoluted to obtain the PDF of the SE (Signal Excess) and the PPD according to the depth of the source and receiver is calculated. Analysis of the changes in the PPD over time when there are internal waves such as soliton packet and internal tide has confirmed that the PPD value is affected by different aspects.

Electron Gun Assembly;Alternative Grid Alignment Systems

  • Brantjes, Con;Zonneveld, Maarten
    • 한국정보디스플레이학회:학술대회논문집
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    • 2002.08a
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    • pp.376-378
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    • 2002
  • Within LG.Philips Displays electron gun assembly different grid alignment methods are used. Besides the commonly used mandrel alignment of grids (Inner Reference System, IRS), also a unique Outer Reference System (ORS) is used as grid alignment method in high-end gun assembly. This alignment method combines alignment accuracy with maximum electron optical design freedom and maximum flexibility in electron gun production.

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The Electrical Properties of Cathode Active Materials in Li Polymer Battery System (리튬고분자 전지의 정극활물질에 관한 전기적 특성)

  • 나재진;박수길;임기조;이홍기;이주성
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1996.05a
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    • pp.273-276
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    • 1996
  • Polyphenylenediamine(PPD) film was prepared with dimethylsulfoxide after the synthesis of PPD by chemical polymerization. The molecular structure of conductive polymer synthesized were discussed by using SEM, FT-IR, NMR. The electrical conductivity measurements were carried out at room temperature. The electrical conductivity which was obtained from electrical instrument was 1.98${\times}$10$\^$-2/ S/cm at ambient temperature.

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Electronic excitation energy quenching of PPD by $CCl_4$ in different solvents

  • Biradar, D.S.;Thipperudrappa, J.;Hanagodimath, S.M.
    • Journal of Photoscience
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    • v.12 no.1
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    • pp.51-54
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    • 2005
  • The electronic excitationenergy quenching of 2, 5-diphenyl-1, 3, 4-oxadiazole (PPD) by Carbon tetrachloride ($CCl_4$) in different solvents viz, n-hexane, n-heptane, toluene, benzene, cyclohexane, 1, 4- dioxane has been carried out at room temperature to understand the role of quenching mechanism. The Stern-Volmer plots have been found to be linear. As probability of quenching per encounter 'p' is less than unity, and the activation energy for quenching '$E_a$' is greater than the activation energy of diffusion '$E_d$', it is inferred that the fluorescence quenching mechanism is not due to material diffusion alone.

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The influence of smoking on the outcome of surgical periodontal therapy -2-year retrospective study (흡연이 치주수술을 포함한 치주치료의 결과에 미치는 영향)

  • Chang, Mun-Taek;Yoon, Joung-Sik;Choi, Seoung-Hwan;Seo, Sung-Chan
    • Journal of Periodontal and Implant Science
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    • v.33 no.3
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    • pp.395-405
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    • 2003
  • The purpose of this study was to examine the effect of smoking on the clinical, radiographic outcome of surgical peridontal therapy. The outcome of periodontal surgery was evaluated in 51 systemically healthy subjects that had received maintenance care. The study subject consisted of 26 smokers and 25 non-smokers. The average age of smoking patients was 51 years old and non-smoking patients was 48 years old. Changes of probing pocket depth(PPD) and radiographic bone height, and number of missing teeth compared between smokers and non-smokers during maintenance period after surgical therapy. The clinical parameters were less favorable in the smoking group compared with non-smoking group. The number and percentage of missing teeth were greater in smokers(21.6%) than non-smokers(l2.4%), especially in molars. The mean presurgery PPD was similar in smokers and non-smokers, molars and premolars, but significantly decreased at least 2 years after surgery. The mean PPD reduction was significantly greater in non-smokers than smokers. Both in the smoking and non-smoking group, the mean PPD reduction was significantly greater in premolars than molars. The radiographical evaluation was also less favorable in the smoking group than non-smoking group. The radiographic evaluation of bone height in smokers showed bone loss. On the contrary, bone height of non-smokers showed bone gain during the period of maintenance. But there was no significant difference between molars and premolars. The clinical and radiographic outcomes of the smoking group was less favorable than those of the non-smoking group. Therefore , smoking seems to influence on the clinical and radiographic outcomes of surgical periodontal therapy.

The Effective Preparation of Protopanaxadiol Saponin Enriched Fraction from Ginseng using the Ultrafiltration

  • Seol, Su Yeon;Kim, Bo Ram;Hong, Se Chul;Yoo, Ji Hyun;Lee, Kun Hee;Lee, Ho Joo;Park, Jong Dae;Pyo, Mi Kyung
    • Natural Product Sciences
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    • v.20 no.1
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    • pp.58-64
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    • 2014
  • In this study, edible protopanaxadiol saponin enriched fraction were prepared by ultrafiltration (UF). Ginseng extract was prepared from mixtures of ginseng main root and rootlet (root: rootlet = 4 : 6). UF system was used the four-piston Diaphragm pump equipped with 5 kDa pore size Hydrosart Cassette made by regenerated cellulose acetate (CA) or 3 kDa pore size Hollow Fiber cartridge made by polyethersulfone (PES). Total ginsenoside contents of concentrated fraction by UF system was found to higher, compared to before those of untreated method. Especially, processing of UF showed the increase of PPD-type ginsenoside, while PPT-type ginsenoside was gradually decreased by both 3 kDa and 5 kDa membrane. After removal of 80% water by the 5 kDa Hydrosart Cassette and by 3 kDa Hollow Fiber cartridge, ginsenoside Rb1 content was higher 37.2 mg/g and 25.3 mg/g than 20.8 mg/g in untreated process. The ratio of Rb1 to Rg1 (Rb1/Rg1) and PPD- to PPT- type ginsenoside (PPD/PPT) were higher in inner fluid of ginseng extract after UF by 3 kDa cartridge (47.1 and 23.5, respectively) and 5 kDa Cassette (25.3 and 11.9, respectively) than those of before UF (5.7 and 3.7, respectively). PPD-type ginsenoside enriched fraction by UF system could be developed as a new ginseng material in food and cosmetic industrials.

The Preparation Characteristic of Dimercaptan-Polyphenylenediamine Cathodes for Lithium Battery (리튬전지용 Dimercaptan-Polyphenylenediamine 정극의 제막특성)

  • Park, Soo-Gil;Lee, Ju-Seong
    • Applied Chemistry for Engineering
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    • v.8 no.1
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    • pp.114-121
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    • 1997
  • The positive active material for polymer film-battery was prepared by using polyphenlenediamine(PPD) synthesized in our lab. and 2,5-dimercapto-1,3,4-thiadiazole(DMcT) with various mixture ratio. The transference measurement of surface morphology and thermal stability of the prepared composite film was carried out by using SEM and TGA, respectively. Electrochemical property and electrical conductivity of the composite film were also measured by using cyclic voltammetry and four-probe method in dry box, respectively. The thermal stability of prepared composite film was up to $200^{\circ}C$. The electrical conductivity of the composite film increased and showed the highest value(about 3 S/cm) when doped at 0.4% $LiCIO_4$ solution. And we could confirm that DMcT was effective on reactivation of PPD through cyclic voltammogram.

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Postpartum Depressive Score and Related Factors Pre- and Post-delivery (산후 우울 수준과 분만전후 관련 요인에 관한 연구)

  • Lee, Sun-Ok;Yeo, Jung-Hee;Ahn, Suk-Hee;Lee, Hyeon-Sook;Yang, Hyun-Joo;Han, Mi-Jung
    • Women's Health Nursing
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    • v.16 no.1
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    • pp.29-36
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    • 2010
  • Purpose: This study aimed to identify the scores of postpartum depression(PPD) on the first day, 1st week, and 6th week after the delivery and to explore their related factors before and after delivery in postpartum women. Methods: With a survey design, 293 postpartum women were recruited from a postpartum unit, Ilsin Christian hospital in Pusan via convenience sampling and were followed at 1st week and 6th week in the outpatient clinic. Results: Results showed that the scores of PPD(EPDS score) were low at postpartum 1st day, 1st week and 6th week but prevalence of PPD(EPDS ${\geq}13$)was 3.1%at 1st day, 8.2%at 1st week and 7.5%at 6th week, respectively. The pre-delivery factors were experience of depression, and the post-delivery factors were baby's sex(1st day), no caregiver for baby(1st week), and no help and concern for taking care of baby from husband and family(1st day and 6th week). The greater satisfaction with becoming a mother and her life, and greater maternal attachment were related to lower level of PPD at the three time points. Conclusion: Regular screening for postpartum depression and supportive and informative education is needed for postpartum women visiting the outpatient clinic for follow-up.