• Nutritional Sciences
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• v.8 no.3
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• pp.189-195
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• 2005

To assess the effect of pinitol supplementation and strength training for two weeks on the anaerobic capacity during and after exercise, and improvement of glucose metabolism during the recovery period of muscular fatigue with repeated acute bouts of cycling exercise, a total of 24 healthy young men were recruited and randomly and equally divided into three groups; pinitol supplementation group (PSG), placebo group (PLG), and control group (CON). Using a randomized double-blinded design, subjects in PSG were provided pinitol supplement, consumed orally 1.2 g/day, and participated in the resistance exercise program and cycling exercise for two weeks. Subjects in PLG underwent the same protocol as those in PSG but consumed the same amount of placebo. No supplementation and exercise program was given to CON. Before and after the intervention, all subjects were tested for their anaerobic capacities evaluated by Wingate test twice separated by 30 min. During the test, peak anaerobic power (PP), mean anaerobic power, total work, and fatigue index were evaluated During resting and recovery, blood samples were drawn and plasma pinitol, myo-inositol, chiro-inositol, insulin, free fatty acid, glucose, and lactate levels were analyzed After two weeks, PP and relative PP of the second biking were improved from the first biking in PSG only (p<0.05). No changes were found in all other variables of Wingate test in all groups. No statistical differences between groups and pre- and post-intervention were observed in concentrations of pinitol, myo-inositol, and chiro-inositol, but pinitol concentration was higher during recovery compared to the baseline in all groups and testings (p<0.05). Lactate level during recovery was higher than the resting level, but no other blood parameters were significantly changed. In conclusion, two weeks of pinitol supplementation in conjunction with short duration of anaerobic training in healthy young men did not induce any obvious benefits in terms of anaerobic capacity and energy metabolism Individual and/or population susceptibility may be one factor responsible for adopting pinitol supplementation.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.36 no.6
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• pp.743-748
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• 2003

An oil boom was set up in order to contain diffused oil from spills and for the retrenchment of damage caused by oil Pollution. Therefore, the oil boom anchor needed proper holding power to endure high resistance from flowing streams and to secure the oil boom around the spill, and must dredge directly into the seabed when it is dropped and block oil outflow immediately. This study investigated the holding power of the danforth anchor and the coastal fishing vessel anchor used for oil booms in the KMPRC (Korea Marine Pollution Response Corporation). For each type, a 30 kg and 20 kg anchor were used. The holding power of the danforth anchors were measured by dropping both weights 10 times. However the coastal fishing vessel anchors were dropped only 5 times each, because no substantial differences were found between drops. In the results of the danforth anchors, an anchor awoke occurred in 2 drops of the 30 kg anchor and in 4 drops of the 20 kg anchor, wherein there was no holding power to be measured. With exception to the anchor awoke cases, the maximum holding power of the danforth 30 kg and 20 kg anchors was 250-520 kg and 123-233 kg, respectively. In the case of the coastal fishing vessel anchors of 30 kg and 20 kg, throughout the experiment, there was no occurrence of an anchor awoke. For the 30 kg and 20 kg anchors, the maximum holding power was measured to be 209-230 kg and 155-170 kg, respectively. Therefore, the holding power of the coastal fishing vessel anchor was shown to be much poorer than that of the danforth anchor. However, the holding power of the danforth anchor was very unstable. Due to the occurrences of anchor awoke, there was no holding power and the measurement value of maximum holding power showed too much variation among the drop tests. Also, after the maximum holding power was achieved, anchor awoke occurred easily. In the case of the coastal fishing vessel anchor was much more stabile, because there was no anchor awoke and no instance where holding power failed. Also the maximum holding power was reached quickly and almost no variation occurred among the drop tests.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.1
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• pp.367-376
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• 2014

The purpose of this study was to investigate the effect of either endurance training only or endurance and weight training on muscle morphology and oxidative enzyme activities in human skeletal muscles. Fourteen healthy males were randomly divided into one of two experimental training groups, either swim exercise training (n=7, ST) or combined exercise training (swim and resistance exercise training; n=7, SWT). The change of muscle fiber type was not significantly different between ST and SWT following 6 weeks of exercise training. Mean cross sectional areas as well as the numbers of capillary of different types of muscle fiber were not also significantly different from baseline for both exercise training groups (p>.05) although the tendency of increase were more notable in SWT. All oxidative enzyme activities (i.e., ${\beta}$-hydroxyl acyl dehydrogenase, citrate synthase, and carnitine palmitoyl transferase) were marginally higher in SWT compared to ST even though statistical power did not reach the level of significance. Based on these results, it was concluded that performing of combined (swimming and weight) exercise training could be the better modality for improving muscle morphological changes and oxidative enzyme activities than performing of only single aerobic exercise intervention in young healthy human skeletal muscles.

• Physical Therapy Korea
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• v.5 no.1
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• pp.63-78
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• 1998

The decrease of muscle power and muscle size between twenties and seventies was about 30% and 40% respectively. The loss of muscle mass by aging resulted in the decrease of muscle power. The loss of muscle mass was due to the decrease of number of Type I fiber and Type II fiber and size of each muscle fiber. The aging skeletal muscle didn't show the loss of glycolysis capacity but showed 20% decrease of the oxidative enzymes and muscle vascularization. The vigorous endurance exercise training with graded intensity played a role in the vascular proliferation, increase of activity of oxidative enzymes and improvement of $VO_2$ max. The graded resistance exercise also played a role in the muscle hypertrophy and increase of muscle power, if it performed with adequate intensity and period. The exercise adaptation of aging skeletal muscle prevented it from sarcopenia, provided the activity of daily living with great effect and provided the aging related disease, that is Type II diabetes mellitus, arteriosclerosis, hypertension, osteoporosis and obesity, with great effect.

• Advances in Energy Research
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• v.2 no.1
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• pp.21-31
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• 2014

The use of a microporous membrane along with Au/C catalyst for direct glycerol alkaline fuel cell was investigated. In comparison with Nafion 112, the microporous Celgard 3401 membrane provides a better cell performance due to the lower ionic resistance as confirmed by impedance spectra. The single cell using Au/C as anode catalyst prepared by using PVA protection techniques provided a higher maximum power density than the single cell with commercial PtRu/C at $18.65mW\;cm^{-2}$ The short-term current decay studies show a better stability of Au/C single cell. The higher activity of Au/C over PtRu/C was owing to the lower activation loss of Awe. The magnitude of current decay indicates a low problem of glycerol crossover from anode to cathode side. The similar performance of single cell with and without humudification at cathode points out an adequate transport of water through the microporous membrane.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.45 no.1
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• pp.14-21
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• 2009

This experimental study was carried out to obtain the base data for saving the man power in the fishing operation of largehead hairtail hand line by using the continuous type hand line system with a rotary device which could make a main line move automatically. In order to solve the twists and entangling on the main line happened during operating test, the resistance board was suspended at the end of the main line at sea. As the result, there were no problems of tangling and so on due to up and down moving of a main line. According to the control of a fixed angle of guide roller, it was possible to prevent the main line to be separated from a side roller and a guide roller. In addition, PVC tube between a guide roller and a side roller enabled a main line to be moved smoothly without any entanglement.

• Journal of Sensor Science and Technology
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• v.14 no.6
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• pp.415-422
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• 2005

Using stretch sensors, a stuttering treatment training device that improve the abnormal breathing of stutterer was designed and developed. To improve stutterer's inadequate breathing method that is one of principal reason of stammering, the device estimates breathing method by checking the changes of the stretch sensor's resistances those are put on the chest and abdomen of user. And a vocal exercise program that carry out exercises only when the user maintains the abdominal breathing was designed. Using a PIC16C711 device that includes an A/D convertor, a main controller was designed and the vocal exercises software was developed using Director and C program with graphic user interface for user convenience. The controller sends the resistance data of sensors to PC through the serial port and the software verifies the breathing method. And the device was designed that the RTS (request to send) pin of serial port in PC is used as a power source so that it can work without any battery or other power source. Three stutterers have carried out the clinical experiments using the implemented device for two months and the results showed it was excellent to alleviate the stuttering.

• Physical Therapy Korea
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• v.10 no.1
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• pp.109-128
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• 2003

This study tested whether repeated measurement of median frequency (MDF)-related variables could express the muscle power changes during a 12-week DeLome strengthening program, by using consecutive overlapping FFT (Fast Fourier transformation) and integrated EMG (IEMG) from surface EMG data for isometric and isotonic exercise. To evaluate the effect of training, the following were recorded every 3 weeks for the elbow flexors and knee extensors of 5 healthy male volunteers: MVC, lRM, limb circumference, and surface EMG during isometric MVC or isotonic contraction at 10RM load. From the EMG data, IEMG and variables from a regression analysis between MDF and time were obtained. MVC, lRM, IEMG, and initial MDF increased linearly over the training period. The fatigue index and slope of the regression line increased temporarily until the 6th week and decreased thereafter. From these results, there appeared to be enhanced neural recruitment of fast twitch fibers in the first 6 weeks and continued enhancement in the recruitment and hypertrophy of fast twitch fibers, which led to increased fatigue resistance, over the last 6 weeks. Accordingly, the MDF and IEMG analysis technique could demonstrate the effect of the program detected significant changes in both isometric and isotonic contractions. EMG analysis methods can be used to estimate the electrophysiological and histological changes in skeletal muscles during a strengthening program.

• Bulletin of the Korean Chemical Society
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• v.33 no.4
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• pp.1123-1127
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• 2012

P-gp (P-glycoprotein) is a member of the ATP binding cassette (ABC) family of transporters. It transports many kinds of anticancer drugs out of the cell. It plays a major role as a cause of multidrug resistance (MDR). MDR function may be a cause of the failure of chemotherapy in cancer and influence pharmacokinetic properties of many drugs. Hence classification of candidate drugs as substrates or nonsubstrate of the P-gp is important in drug development. Therefore to identify whether a compound is a P-gp substrate or not, in silico method is promising. Recursive Partitioning (RP) method was explored for prediction of P-gp substrate. A set of 261 compounds, including 146 substrates and 115 nonsubstrates of P-gp, was used to training and validation. Using molecular descriptors that we can interpret their own meaning, we have established two models for prediction of P-gp substrates. In the first model, we chose only 6 descriptors which have simple physical meaning. In the training set, the overall predictability of our model is 78.95%. In case of test set, overall predictability is 69.23%. Second model with 2D and 3D descriptors shows a little better predictability (overall predictability of training set is 79.29%, test set is 79.37%), the second model with 2D and 3D descriptors shows better discriminating power than first model with only 2D descriptors. This approach will be used to reduce the number of compounds required to be run in the P-gp efflux assay.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.2
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• pp.487-495
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• 2021

The voltages mainly used in ships are 450 [V], 6.6 [kV], and 11 [kV], and an earthed system is applied to ensure the stability of the power distribution system. In general, low-voltage ships using 450 [V] apply an unearthed system, while high-voltage ships using 6.6 [kV] or 11 [kV] use a high-resistance earthed system. When an earth fault occurs in a ship's power distribution system, the voltage of the healthy phase increases to the line-to-line voltage or higher, which causes an excessive impact on the insulation of the cable. Thus, analyzing this behavior is very important. In this paper, we investigate the characteristics of the line-to-earth voltage variation according to earth faults and a recognition procedure of a faulty phase using the symmetrical coordinate method for a high-resistance earthed system and unearthed system. A mathematical model of the line-to-earth voltage was derived through the symmetric coordinate method, and the ship voltage for simulations was selected as 6.6 [kV] and 450 [V]. A MATLAB simulation proved that this method can determine the highest increase of the line-to-earth voltage, which leads by 120° on the faulty phase, and it accurately judges the faulty phase in both earthed systems.