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Physicochemical properties and physiological activity of bean sprouts extract containing Hovenia dulcis Thunb concentrates

  • Ji-An Heo;Wool-Lim Park;Hye-Ji Min;Jeong-Ho Kim;Yeong-Seon Won;Kwon-Il Seo
    • Food Science and Preservation
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    • v.30 no.4
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    • pp.617-629
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    • 2023
  • Reactive oxygen species are the byproducts of metabolic processes in the body, However, excessive amount may cause side effects such as cancer. Therefore, to reduce the production of these species, but their long-term administration at high doses may induce side effects. Hence, natural materials with antioxidant activities are attracting attention. Two of these natural materials are soybean sprouts and Hovenia dulcis Thunb. fruits, but few studies have evaluated the effects of their combination. Thus, we prepared a soybean sprout extract containing 1.5% H. dulcis Thunb. fruit concentrate (BHM) to develop a functional food material derived from natural products and then confirmed its physicochemical properties and physiological activity. Among the organic acids detected in BHM, malic acid exhibited the highest content of 1,451.03 ppm, and the main free sugars were glucose (645.48 ppm) and fructose (738.11 ppm). Taurine was the most abundant free amino acid at a concentration of 11.95 ppm, followed by those of arginine (10.97 ppm) and glutamic acid (10.16 ppm). Analyses of the mineral components revealed large amounts of Zn and Fe in BHM, and the respective total polyphenol and flavonoid contents in BHM were 957.16 and 601.93 ppm. The DPPH radical and H2O2 scavenging activities and reducing power indicated excellent antioxidant efficacy compared to the positive controls. Furthermore, blood alcohol and acetaldehyde concentrations were measured to confirm the hangover-relieving effects of BHM, with both significantly decreased (p<0.05). BHM displays potential for development as a functional food, and the results of this study may be used as basic data in further research.

Fluticasone Propionate and Beclomethasone Dipropionate in Asthmatic Patients (천식환자에서 Fluticasone propionate와 Beclomethasone dipropionate의 치료효과 비교)

  • Yang, Dong-Kyu;Kim, Young-Sam;Ahn, Chul-Min;Ko, Won-Ki;Chang, Joon;Kim, Sung-Kyu;Lee, Won-Young
    • Tuberculosis and Respiratory Diseases
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    • v.47 no.5
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    • pp.629-641
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    • 1999
  • Background: Corticosteroid is most potent and effective anti-inflammatory medication currently available and inhaled form has been used in the long-tenn control of asthma. Fluticasone propionate(Flixotide/Flovent: FP) is highly potent and topically active inhaled corticosteroid and has at least twice the potency of beclomethasone dipropionate(BDP) in the control of asthma. The aim of this study was to compare the efficacy of FP and BDP in several aspects. Method: Fifty patients with asthma were treated in a randomized, parallel group study of 4 weeks duration. During 2-week run-in period $\beta_2$-agonist was administered. After run-in period, FP $500{\mu}g/day$ was administered via Diskhaler or BDP $800{\mu}g/day$ via reservoir dry-power device. During the run-in and treatment period, morning and evening peak expiratory flow rate(PEFR) were measured daily. Daytime and nighttime asthma symptoms, daytime and night-time rescue bronchodilator use were checked daily. $FEV_{1.0}$ and FVC were measured biweekly in both groups. Results: Three patients treated with FP and seven patient treated with BDP were dropped out. Therefore forty patients completed the study. Morning and evening PEFR was increased and diurnal variation of PEFR decreased significantly in both groups. $FEV_{1.0}$ increased significantly in FP treatment group but not in BDP group. There were also improvements in daytime and night-time asthma symptoms, daytime and night-time rescue bronchodilator use in both groups after treatment There were no significant difference between groups in any of the efficacy parameters. Therapeutic effects were demonstrated earlier in patient treated with FP than BDP. Conclusion: In this study, $500{\mu}g/day$ fluticasone propionate was as effective as $800{\mu}g/day$ beclomethasone dipropionate in the control of asthma. Therapeutic effects were demonstrated earlier in patient treated with FP than BDP without adverse effect.

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Studies on Application Method and Safety of Macrogranule(GG) Herbicide for Remote-controlled Aerial Application (무인헬기용 Macrogranule(GG) 제초제의 안정성 및 살포방법 연구)

  • Yoon, Cheol-Su;Bae, Chang-Hyu;Lee, Sheong-Chun;Kim, Kyung-Hyun;Lee, Kye-Hwan;Cho, Tae-Kyoung;Hwang, In-Cheon
    • Korean Journal of Weed Science
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    • v.31 no.3
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    • pp.294-307
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    • 2011
  • This experiment carried out to confirm characteristics of macrogranule (GG) for herbicidal efficacy by using remote-controlled aerial application (RCAA) to control annual and perennial weeds in rice paddy field, application methods, and application times of formulation types. Particle of 500 g GG having average diameter of 2.5~3 mm was over 85 percent, the bulk density of the particle was $0.2\sim0.4g\;mL^{-1}$ and the particle was water floating granule. Active ingredients and external form of halosulfuronmethyl+mefenacet GG remained stable under condition of storage stability test. The disintegration time of the GG was faster as the water temperature was increased. But disintegration time was not affected by pH on the water conditions. By using hand, spoon and power applicator, drift distances of GG were 4~5m, 7 m and 10~12 m, respectively. GG showed good herbicidal efficacy and plant safety in all of the application methods such as, using hand, spoon, power applicator and RCAA. Application times of GG, GR, SC and TB by hand in $4,000m^2$ were 38 min. 4 sec, 42 min. 20 sec, 38 min. 10 sec and 21 min. 4 sec, respectively, but application time of GG by using RCAA was 1 min 32 sec. According to appearance and characteristics of formulation types, suspension concentrate (SC) and GG were possible formulation types for RCAA.

Effect of Pulse Energy and Pulse Repetition Rate at the Identical Total Power During Enamel Ablation Using an Er:YAG Laser (Er:YAG 레이저를 이용한 치아 삭제시 동일출력에서 펄스에너지와 조사반복률의 영향)

  • Won, Jung-Yeon;Kim, Mee-Eun;Kim, Ki-Suk
    • Journal of Oral Medicine and Pain
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    • v.31 no.3
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    • pp.223-229
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    • 2006
  • The objectives of this study was to investigate the amount of tooth ablation and the change of intrapulpal temperature by Er:YAG laser as it relates to pulse energy and pulse repetition rate at the identical power and, thereby, to reveal which of the two parameters strongly relates with ablation efficiency and intrapulpal temperature. Extracted healthy human molar teeth were sectioned into two pieces and each specimen was irradiated within the combination of pulse energy and pulse repetition time at the same power of 3W; $300mJy{\times}10Hz$ group, $200mJy{\times}15Hz$ group, and $150mJy{\times}20Hz$ group. Each specimen comprised ten tooth specimens. A laser beam with conjunction of a water flow rate of 1.6 ml/min was applied over enamel surfaces of the specimens during 3 seconds and the ablation amount was determined by difference in weight before and after irradiation. To investigate the temperature change in the pulp according to the above groups, another five extracted healthy human molar teeth were prepared. Each tooth was embedded into resin block and the temperature-measuring probes were kept on the irradiated and the opposite walls in the dental pulp during lasing. When the power was kept constant at 3W, ablation amount increased with pulse energy rather than pulse repetition rate (p=0.000). Although intrapulpal temperature increased with pulse repetition rate, there were no significant differences among the groups and between the irradiated and the opposite pulpal walls, except at a condition of $150y{\times}20Hz$ (p=0.033). Conclusively, it is suggested that ablation efficacy is influenced by pulse energy rather than pulse repetition rate.

The Effect of Emotional Intelligence on School Adjustment of Specialized Vocational High School Students (특성화고등학교 학생의 정서지능이 학교적응에 미치는 영향)

  • Park, So-Hyeon;Song, Gyo-Won;Lee, Chang-Hoon
    • 대한공업교육학회지
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    • v.43 no.1
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    • pp.41-57
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    • 2018
  • The purpose of this study is to help research and application about effective strategies to improve school adjustment of students by investigating the influence of specialized vocational high school students' emotional intelligence on school adjustment. A survey was conducted to 760 engineering major students at the vocational high schools from 18 vocational high schools of 5 major metroplex. A questionnaire consists of measurement tool for emotional intelligence (40 questions) and one for school adjustment (20 questions). The findings of this study are as follows: First, students with high emotional intelligence showed a higher level of school adjustment than students with lower emotional intelligence, and they also has a higher standard in all sub factors of school adjustment, Second, it is found that the explanatory power of emotional intelligence on school adjustment is 33.6%. It means the higher the emotional intelligence of the students, the higher the school adjustment, so it can be seen that emotional intelligence might be one alternative that increases school adjustment for specialized vocational high school students. Furthermore, emotional intelligence shows the greatest explanatory power to peer relationship in school adjustment sub factors. This is showed that students with high emotional intelligence have good peer relationship than students with lower emotional intelligence relatively. Also, it can be known that school adjustment is high because the better peer relationship is, the higher self-efficacy, class immersion, resilience and so on are.

An Evaluation of Transfer of Training Effects on Nuclear Power Plant MCR Operators

  • Kim, Jung Ho;Byun, Seong Nam
    • Journal of the Ergonomics Society of Korea
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    • v.32 no.1
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    • pp.77-85
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    • 2013
  • Objective: The aim of this study sets factors from previous research known to impact transfer effects as the independent variables, and examines their relationship with the dependent variables, near transfer effects and far transfer effects. Background: Transfer of Training refers to the application of what learners acquire knowledge and skills in training programs to their job. The ultimate goal of training is to apply what employees learn in training sessions to their workplace. In this sense, transfer of training has been a vital concern for training effectiveness. For training to be effective, trainees(learners) should be able to use what they learn in training program back on the job. Method: For this research purpose, this study conducted a survey on 170 nuclear operators in nuclear education and training center. Of these, survey result from the 167 recruits were sampled. Theoretical model of this study is based on Holton & Baldwin's(2003) distance model of transfer effects. This study sets transfer effects(near transfer, far transfer) as the main dependent variables. Meanwhile, the independent variables are trainee characteristics, training characteristics, organizational transfer climate. Each independent variable has subordinate variables. Subordinate variables of trainee characteristics are self-efficacy, motivation to learn, motivation to transfer and ability to transfer. Subordinate variables of training characteristics are training contents, ability of trainers, training design, training climate. The last Subordinate variables of organizational transfer climate are support of supervisors, support of peer, support of organization. Conclusion: As a analysis result, trainee characteristics appeared to be in effect only significant influence near far transfer of training, the effect of the far transfer of training, there is no significant. In addition, the training characteristics appeared to be having a significant influence on near and far transfer effects. Organizational transfer climate appeared to be having a significant influence on near and far transfer effects. Finally, near transfer effect appeared to be having a significant influence on far transfer effects. Application: Results of this analysis in the study to training organization and training characteristics of the transition environment effects on nuclear power institutions and operators training organization having a significant impact that says. The transfer of knowledge and technology, as well as that can be applied to a new situation in terms of education and training are important characteristics.

The Effect of Saururus Chinensis Extracts on Antioxidant Activity and Melanin Synthesis (삼백초 추출물이 항산화활성과 멜라닌 합성에 미치는 영향)

  • Jung, Somi;Park, Hyejeong;Kim, Jaeho;Oh, Yunghee;Kim, Moon-Moo
    • Journal of Life Science
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    • v.30 no.10
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    • pp.851-859
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    • 2020
  • Saururus chinensis has white roots, leaves, and flowers and is known to have antibacterial activity and anti-cancer efficacy. The aim of this study was to investigate the effect of the ethyl acetate fraction of a methanol extract of Saururus chinensis (SCEA) on antioxidant activity and melanin synthesis. SCEA at 64 ㎍/ml showed 62% of the DPPH radical scavenging activity of vitamin C, and its reducing power was 33% greater than that of vitamin C. Tyrosinase activity was 26% higher and melanin synthesis was 44% higher in the presence of SCEA at 64 ㎍/ml than in a blank group in a dopa oxidation assay. MTT assay showed that SCEA displayed cytotoxicity above 0.5 ㎍/ml, and SCEA at 1 ㎍/ml increased melanin synthesis by 69% in live B16F1 cells. SCEA was also separated into 13 fractions by silica column chromatography, and fraction 2 (Fr. 2) showed the highest DPPH radical scavenging activity, reducing power, and melanin synthesis. SCEA also promoted melanin production in live cells. LC-MASS analysis showed that Fr.2 had a molecular weight of 239, and these findings suggest that SCEA could be available for the promotion of melanin synthesis in black hair.

Optimal Design of Permanent Magnet Thrust Bearings (영구자석형 스러스트 베어링의 최적 설계)

  • Yoo, Seong-Yeol;Kim, Woo-Yeon;Kim, Seung-Jong;Lee, Wook-Ryun;Bae, Yong-Chae;Noh, Myoung-Gyu
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.35 no.4
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    • pp.353-358
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    • 2011
  • In this paper, we describe a process for optimally designing a ring-type permanent magnet thrust bearing. The bearing consists of two sets of permanent magnet rings. One set is located inside the other set. An axial offset between the two sets creates axial force, which results in a thrust bearing function. In order to realize an optimal design of the bearing where the required load capacity of the bearing is achieved with the least magnet volume, we derived analytical design equations by adopting the equivalent current sheet (ECS) method. We considered the following two types of magnet arrays: axial arrays and Halbach arrays. These two types of arrays are optimized using the analytical design equations. The results of the optimization are verified using three dimensional (3D) finite element analyses (FEA). The results show that the Halbach array can achieve the required load capacity with less amount of permanent magnet than the axial array does. The efficacy of the ECS method is also verified by using 3D FEA. It is found that the accuracy of ECS method is more sensitive to the underlying assumptions for the Halbach array than for the axial array.

Characterization of Porcine Tissue Perforation Using High-Power Near-Infrared Laser at 808-nm Wavelength (808 nm 파장의 고출력 근적외선 레이저 조사 시 돼지 조직의 천공 특성 연구)

  • Kim, Seongjun;Cho, Jiyong;Choi, Jaesoon;Lee, Don Haeng;Kim, Jung Kyung
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.37 no.9
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    • pp.807-814
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    • 2013
  • A fundamental study on laser-tissue interaction was conducted with the aim of developing a therapeutic medical device that can remove lesions on the intestinal wall by irradiating a high-power 808-nm infrared laser light incorporated in an endoscopic system. The perforation depth was linearly increased in the range of 1~4 mm in proportional to laser output (3~12 W) and irradiation time (5~20 s). We demonstrated that the perforation depth during laser irradiation was varied according to the tissue property of each extracted porcine organ. The measurement of the temperature distribution suggests that the energy is localized in the irradiation spot and transferred to deep tissue, which protects the surrounding tissue from thermal injury. These results can be used to set the driving parameters for a laser incision technique as an alternative to conventional surgical interventions.

Antioxidant Activity of Fermented Wild Grass Extracts (산야초 발효액의 항산화 활성)

  • Lee, Young-Jun;Yoon, Bo-Ra;Kim, Dan-Bi;Kim, Myoung-Dong;Lee, Dae-Won;Kim, Jae-Keun;Lee, Ok-Hwan
    • The Korean Journal of Food And Nutrition
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    • v.25 no.2
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    • pp.407-412
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    • 2012
  • Wild grass is edible, and it grows in the mountains or field areas. Wild grass has diverse biological effects, such as antiobesity, anti-cancer, antioxidant activities and immune stimulation. Currently, many studies are aimed at enhancing the efficacy of medicinal foods on biological activity using a bioconversion technology, including the fermentation process. In this study, the quality characteristics and antioxidative activity of the fermented wild grass was investigated. The antioxidant activity of fermented wild grass was assessed by various radical scavenging assays using DPPH(2,2-diphenyl-1-picrylhydrazyl), FRAP(ferric ion reducing antioxidant power), reducing power, and ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)). Moisture contents of the fermented wild grass is $49.6{\pm}0.06%$. Contents of crude ash, crude protein, and crude fat were $0.65{\pm}0.01$, $0.65{\pm}0.04$, and $3.3{\pm}0.59%$, respectively. Moreover, fermented wild grass showed that the hunter's color values were 80.36(lightnees), 11.47(redness), and 44.53(yellowness), respectively. Total phenolic contents of the fermented wild grass was $1,185{\pm}159{\mu}g$ GAE(gallic acid equivalent)/g. The antioxidative activities of the fermented wild grass were significantly increased in a dose dependent manner. In addition, fermented wild grass did not show any cytotoxicity up to 500 ${\mu}g/m{\ell}$. However, the anti-adipogenic effect of the fermented wild grass extract was barely detectable. This antioxidant potential is partly due to the phenolic compounds that are present in the fermented wild grass extracts.