• Food Science of Animal Resources
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• v.43 no.6
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• pp.1087-1110
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• 2023

The growing demand for sustainable food production and the rising consumer preference for fresh, healthy, and safe food products have been driving the need for innovative methods for processing and preserving food. In the meat industry, this demand has led to the development of new interventions aimed at extending the shelf life of meats and its products while maintaining their quality and nutritional value. Cold plasma has recently emerged as a subject of great interest in the meat industry due to its potential to enhance the microbiological safety of meat and its products. This review discusses the latest research on the possible application of cold plasma in the meat processing industry, considering its effects on various quality attributes and its potential for meat preservation and enhancement. In this regard, many studies have reported substantial antimicrobial efficacy of cold plasma technology in beef, pork, lamb and chicken, and their products with negligible changes in their physicochemical attributes. Further, the application of cold plasma in meat processing has shown promising results as a potential novel curing agent for cured meat products. Understanding the mechanisms of action and the interactions between cold plasma and food ingredients is crucial for further exploring the potential of this technology in the meat industry, ultimately leading to the development of safe and high-quality meat products using cold plasma technology.

• The Journal of Small Business Innovation
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• v.19 no.1
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• pp.17-35
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• 2016

Understanding key factors that affect entrepreneurial intention of university students is important to establish effective pedagogy for educating potential entrepreneurs. This cross-cultural study examines the direct effects of entrepreneurship education and self-efficacy on entrepreneurial intention of university students, and further examined how self-efficacy interacts with an entrepreneurship education in promoting entrepreneurial intention of Korean and Chinese university students. Empirical findings of this study suggest that entrepreneurship education and self-efficacy affect significantly entrepreneurial intention of university students in both countries. The proposed moderation effect of self-efficacy was supported for Korea but not China. The implications of the study were discussed and presented in terms of theoretical and practical aspects.

• Journal of the Korean Society of Physical Medicine
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• v.15 no.4
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• pp.131-143
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• 2020

PURPOSE: The purpose of this study was to determine if an exercise program with vertical vibration can improve balance, walking speed, muscle strength and falls efficacy in the healthy elderly. METHODS: A total of 28 elderly were randomly divided into two groups: vertical vibration exercise group (exercise with vertical vibration) (N = 14) and control group (exercise without vibration) (N = 14). The exercise program, comprising calf raise, deep-squat, semi-squat, front lunge, and leg abduction was conducted with or without vibration, respectively. Subjects in each group participated in the 30 minutes training program, 2 times per week for 6 weeks. In both groups, the balance evaluation system (BT4) was used to evaluate standing balance, and walking speed was measured using the 10MWT. The manual muscle test system was applied to evaluate the knee extensor and ankle planter flexor muscle strength of the subjects, whereas the Korean falls efficacy scale (K-FES) evaluated the falls efficacy. RESULTS: After intervention, the vertical vibration group showed significantly higher changes compared to the control group, in the parameters of standing balance (P < .05), 10MWT (P < .05), left knee extensor (P < .05), right knee extensor (P < .01), both ankle plantar flexors (P < .05), and K-FES (P < .05). CONCLUSION: The exercise program with vertical vibration has the potential to improve balance, walking speed, muscle power and falls efficacy in the elderly.

• Journal of Microbiology and Biotechnology
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• v.19 no.6
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• pp.622-628
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• 2009

In the present study, the therapeutic potential of purified and well-characterized bacteriophages was evaluated in thermally injured mice infected with Klebsiella pneumoniae B5055. The efficacy of five Klebsiella phages (Kpn5, Kpn12, Kpn13, Kpn17, and Kpn22) was evaluated on the basis of survival rate, decrease in bacterial counts in different organs of phage-treated animals, and regeneration of skin cells as observed by histopathological examination of phage-treated skin. Toxicity studies performed with all the phages showed them to be non-toxic, as no signs of morbidity and mortality were observed in phage-treated mice. The results of the study indicate that a single dose of phages, intraperitoneally (i.p.) at an MOI of 1.0, resulted in significant decrease in mortality, and this dose was found to be sufficient to completely cure K. pneumoniae infection in the burn wound model. Maximum decrease in bacterial counts in different organs was observed at 72 h post infection. Histopathological examination of skin of phage-treated mice showed complete recovery of burn infection. Kpn5 phage was found to be highly effective among all the phages and equally effective when compared with a cocktail of all the phages. From these results, it can be concluded that phage therapy may have the potential to be used as stand-alone therapy for K. pneumoniae induced burn wound infection, especially in situations where multiple antibiotic-resistant organisms are encountered.

• Herbal Formula Science
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• v.30 no.2
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• pp.59-66
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• 2022

Objectives : This study is to investigate whether Carthami flos exhibits a synergistic effect on the apoptotic effect of doxorubicin on human gastric cancer cells. Methods : We used AGS, a human gastric cancer cell line. To investigate the apoptotic efficacy of doxorubicin and Carthami flos, MTT and CCK-8 methods were used. To confirm apoptosis, cell cycle and mitochondrial membrane potential changes were confirmed. To investigate the mechanism of apoptosis, the reactive oxygen species (ROS) experiment was performed. Results : 1. Doxorubicin or Carthami flos induced cell death in the human gastric cancer cell line AGS. 2. Carthami flos showed a synergistic effect of cell death by doxorubicin. 3. The cell cycle and mitochondrial membrane potential changes revealed that cell death was apoptosis. 4. Apoptosis was related to reactive oxygen species (ROS) generation. Conclusions : This result shows the anticancer synergistic effect of Carthami flos in gastric cancer cells, and is considered to be an important basis for the development of anticancer drugs for Carthami flos.

• The Journal of Internal Korean Medicine
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• v.33 no.4
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• pp.533-542
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• 2012

Objectives : We try to compared the efficacy of six herbal medicines, Rhizoma Alismatis (RA), Fructus Crataegi (FC), Fructus Lycii (FL), Radix Curcumae (RC), Radix Salviae Miltiorrhizae (RSM), and Herba Artemisiae Scopariae (HAS), constituting KHchunggan-tang which was previously proven to be hepatoprotective on non-alcoholic fatty liver disease with combined properties of cellular steatosis, ROS production, and cytoprotection. Methods : HepG2 cells were pretreated with aqueous extracts of the six herb medicines at concentrations of 1, 10, 50 and 100 ${\mu}g/ml$ each, and treated with 0.5 mM palmitate consecutively. After 21 hrs, cell viability was assessed using MTT assay, and the percentage of cells with sub-G1 DNA content was measured using fluorescence-activated cell sorting after propidium iodide staining. Results : The first three extracts, RA, FC, and FL restored cell viability reduced by palmitate in MTT assay, and RA, FC, FL and RC inhibited palmitate-induced apoptosis in sub-G1 analysis. FL showed relatively weak potential only at tested maximal dose, and RA showed the greatest higher efficacy on this experimental cellular model of nonalcoholic fatty liver disease. Conclusions : According to this comparative experiment, Rhizoma Alismatis seems to have the most powerful potential among the six herbs constituting KHchunggan-tang, and consecutive further study seems to be required for more standardized and effective clinical application of KHchunggan-tang for treatment of non-alcoholic fatty liver disease.

• Nutrition Research and Practice
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• v.12 no.6
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• pp.527-534
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• 2018

BACKGROUND/OBJECTIVES: Veggiecation was developed to improve children's vegetable consumption through classroom lecture and cooking activities. In this study, we explored potential determinants of vegetable consumption behavior and intention, and examined the impact of Veggiecation on vegetable consumption behavior, intention and personal factors among Korean children. SUBJECTS/METHODS: The 4-week Veggiecation program was implemented for second-graders in South Korea (35 children in the intervention group, 36 in the control group). We identified personal and environmental factors influencing vegetable consumption behavior and intention using multiple regression analyses. Consumption behavior, intention and, personal factors such as preference, attitude, and self-efficacy were compared between the groups before and after the intervention. RESULTS: Children's vegetable consumption behavior was significantly correlated with personal, social-, and physical-environmental factors as well as intention. Among the variables, preference was the most influential factor on intention, and attitude and intention had great influence on the behavior. After the program, children in the intervention group demonstrated significant improvements in vegetable consumption, intention, attitude, preference, and self-efficacy compared with children in the control group. CONCLUSION: Veggiecation, a school-based culinary nutrition education program, improved vegetable consumption and intention, as well as preference, attitude, and self-efficacy, in second-graders. Veggiecation has great potential, as a global program, to increase children's vegetable consumption. This program can be expanded through various channels, such as after-school programs or camps, to provide a positive impact for children.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.15 no.6
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• pp.155-166
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• 2020

The purpose of this study is to explore the impact of self-efficacy, hope, and resilience, which are factors of the positive psychology capital of the re-startup CEO, on the quality of decision-making through the absorption capacity, and the effect of the re-startup's absorption capacity. In particular, this study was started from the question of how positive psychological capital would affect to the re-startup CEO. The survey was conducted from re-founders who received funding from Korea SMEs & Startups Agency. And 144 sample data were analyzed by using SPSS 24.0 for descriptive statistics and by using Smart PLS 3.0. for SEM. The factors of Positive Psychological Capital were extracted to three factors: self-efficacy, hope, and resilience. As a result, it is shown that self-efficacy had a positive effect on potential absorption capacity, and hope had no effect on potential absorption capacity, and positive effects on realized absorption capacity. Resilience has been shown to have a positive effect on potential absorption and realized absorption capacity. It has been shown that potential absorption and realized absorption have a positive effect on the quality of decision making. This study is intended to provide theoretical and practical implications.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.64 no.5
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• pp.732-738
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• 2015

In ac discharge, emission efficiency shows an time-varying characteristics during discharge. The phenomenon is caused by the potential distribution changes during the discharge, which indicates that a specific potential distribution can contribute to a high improvement of the emission efficiency. To create an artificial environment for a potential distribution favorable to emission efficiency, we used the asymmetric electrode structure and proved the capability. Our results showed that the ratio of the area of anode to cathode became larger, the emission efficacy was greatly improved.

• Journal of Ginseng Research
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• v.48 no.4
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• pp.347-353
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• 2024

Ginsenosides in ginseng are known for their potential health benefits, including antioxidant properties and their potential to exhibit anticancer effects. Besides a various range of coding genes, ginsenosides impose their efficacy by targeting noncoding RNAs. Long noncoding RNA (lncRNA) has gained significant attention from both basic and clinical oncology fields due to its involvement in various cancer cell activities such as proliferation, apoptosis, metastasis, and autophagy. These events can be achieved either by lncRNA alone or in association with microRNAs or proteins. This review aims to summarize the diverse activities of lncRNAs that are regulated by ginsenosides, focusing on their role in regulating target genes through signaling pathways in human diseases. We highlight the results of studies on the expression profiles of lncRNAs induced by ginsenosides in efforts to inhibit cancer cell proliferation. Finally, we discuss the potential and challenges of utilizing lncRNAs as diagnostic markers for disease treatment.