• Clinical and Molecular Hepatology
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• v.24 no.4
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• pp.374-383
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• 2018

Background/Aims: There have been numerous efforts to reduce mother-to-child transmission (MTCT) of hepatitis B virus (HBV) with antiviral agents during pregnancy. However, there are limited data regarding the outcomes of pregnant women after delivery. This study was performed to evaluate the efficacy of antiviral agents in preventing MTCT of HBV and maternal long-term outcomes. Methods: The HBV-infected pregnant women treated with antiviral agents to prevent MTCT were retrospectively reviewed. Forty-one pregnant women who received telbivudine or tenofovir during late pregnancy (28-34 week) were analyzed. Hepatitis B virus surface antibody (HBsAb) positivity was tested in 43 infants after 7 months of birth. Eleven mothers were followed >1 year after delivery. Results: The mean HBV DNA titer before antiviral therapy was 8.67 (6.60-9.49) log copies/mL, and the median age at delivery was 32 years (range, 22-40). Eleven patients were treated with tenofovir and 30 with telbivudine. The median duration was 57 days (range, 23-100), and the median HBV DNA titer at birth was 5.06 log copies/mL (range, 2.06-6.50). Antiviral treatments were associated with significant HBV DNA reduction (P<0.001). Among 43 infants (two cases of twins), HBsAb was not detected in two, subsequently confirmed to have HBV infection. Biochemical flare was observed in two of 11 mothers followed >12 months, and an antiviral agent was administered. Conclusions: Antiviral treatment during late pregnancy effectively reduced MTCT. Long-term follow-up should be required in such cases. In addition, given that maternal biochemical flare occurred in 18% of mothers, re-administration of antiviral agents might be required.

• Journal of Trauma and Injury
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• v.18 no.2
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• pp.112-118
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• 2005

Background: N-Butyl Cyanoacrylate (NBCA) is a liquid embolic material that can be useful for transcatheter arterial embolization (TAE) of acute bleeding especially in patients with coagulopathy, because it does not depend on coagulation for its therapeutic effect. The aims of this study were to evaluate the clinical efficacy and safety of TAE with NBCA in acute bleeding patients. Methods: Between August 2003 and September 2004, TAE using NBCA for acute bleeding was performed in 23 patients (16 men, 7 women; mean age, 56.5years). The causes of bleeding were gastric ulcer (n=5), postoperative bleeding (n=4), post-biopsy bleeding (n=3), postpartum bleeding (n=3), duodenal ulcer (n=2), angiodysplasia (n=2), gastric lymphoma (n=1), iatrogenic injury (n=1), CMV gastritis (n=1), stab injury of the liver (n=1). TAE was performed using 1:3 mixtures of NBCA and iodized oil. The angiographic and clinical success rate, recurrent bleeding rate, procedure-related complication and clinical outcomes were evaluated. Results: The angiographic and clinical success rate was 100% and 91.3% (21/23), respectively. There was no serious ischemic complication. Recurrent bleeding occurred in 2 patients (8.7%) and they were managed with successful second TAE (n=1) and endoscopic treatment (n=1). Nine patients (39.1%) had coagulopathy at the time of TAE and clinical success rate in this group of patients was 88.9% (8/9). Conclusions: TAE with NBCA is highly effective and safe treatment modality for acute bleeding patients, especially when the patient has a coagulopathy.

• Clinical and Experimental Reproductive Medicine
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• v.12 no.1
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• pp.71-81
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• 1985

A clinical analysis has been made on 717 cases of tubal sterilization which had been performed at the Dept. of Obstet. & Gynecol., Kyung Hee University Hospital from Jan. 1, 1976 to Dec. 31, 1980. The results are as follows: 1) Prominant age group consisted of those 26-30 years old with frequency of 43.9%, the average being 30.6 years old. 2) Women having 2 living children represented 52.4% of the total and the average No. of living children was 2.5. 3) According to the sex of their children, 29.7% of all cases had one son and one daughter. 12.1% of cases had no son, while 25.7% of cases had no daughter, which showed a trend of male preference. 4) 47.7% of total cases had not experienced artificial abortion before sterilization and the mean No. of artificial abortion was 1.8. 5) With respect to interval between last delivery and tubal sterilization, 76.1% of cases was sterilized within postpartum period (including-c-section) and 12.4% of cases was sterilized within 3 years. 6) The contraceptive methods prior to sterilization were 42.8% with no method used, 17.7% by condom, 16.6% by oral pills, 14.9% by IUD method. 7) 84.5% of puerperal sterilization operation was performed within 48 hours after bearing. 8) Sterilization procedures were coincidentally performed with appendectomy (36.7%), D&E (15.8%), perineorrhaphy (5.0%), salpingectomy (1.8%), and ovarian cystectomy (1.5%). 9) General anesthesia was performed in the majority cases (88.4%). 10) Complications after the procedure were encountered in 7.8% (56 cases), but no intensive medical care was required for these complications. 11) The failure (0.3%) resulting in intrauterine pregnancies occured after the laparoscopic sterilization.

• The Journal of Korean Obstetrics and Gynecology
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• v.26 no.4
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• pp.48-65
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• 2013

Objectives: We took breast milk samples and analyzed them using HPLC and LC/MS/MS, to evaluate the effects of taking Saenghwa-tang during breastfeeding on breast milk. Methods: The study participants were 20 lactating women who admitted in Korean medical postpartum care center. Breast milks were collected from paticipants who have been administrated Saenghwa-tang for more than 3 days. We used HPLC and LC/MS/MS for the determinations of amygdalin, liquiritins, 6-gingerol, decursin and decursinol angelate in Saenghwa-tang. Results: 1. Participants' $Mean{\pm}S.D$ (standard deviation) of age is $31.05{\pm}1.96$, and 15 participants had normal delivery and 5 participants had cesarean delivery. 12 participants were primipara and 8 participants were multipara. $Mean{\pm}S.D$ of lactating date is $9.4{\pm}0.94$. 2. Using HPLC, we learned LOQ level peak that matches the peak retention time of standard components of Saenghwa-tang was not detected from 20 breast milk samples. 3. Using LC/MS/MS, decursin of Angelicae Gigantis Radix was detected from HMSP 02, HMSP 04, HMSP 06, HMSP 11, and the each concentrations are 16, 2, 64, 11 ppb. Liquiritin of Glycyrrhizae Radix was not detected from HMSP 13~HMSP 18. Conclusions: Data obtained by this approach shows that this method is reliable and suitable for determining the safety of taking Saenghwa-tang during breastfeeding.

• Journal of the East Asian Society of Dietary Life
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• v.14 no.1
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• pp.27-33
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• 2004

The objectives of the present study were to measure the content of iron, copper and zinc in human milk and to estimate the intake of iron, copper and zinc of breast-fed infants during the early period of lactation. Twenty-five lactating women who delivered in a hospital in Seoul volunteered for the study. Milk samples were collected at day 2, 3, 4, 5, 6, 7, 15 and 30 postpartum. The contents of iron, copper and zinc were determined using the atomic absorption spectrophotometer after wet digestion. The intakes of iron, copper and zinc of infants were estimated by multiplization with the infant milk intake reported in our laboratory. The content of iron was 0.58 $\mu\textrm{g}$/g in colostrum, 0.48 $\mu\textrm{g}$/g in transitional milk and 0.39 $\mu\textrm{g}$/g in mature milk while the estimated iron intake of infants was 271, 255 and 259 $\mu\textrm{g}$/day, respectively. The content of copper in the milk was 0.45 $\mu\textrm{g}$/g in colostrum, 0.43 $\mu\textrm{g}$/g in transitional milk and 0.33 $\mu\textrm{g}$/g in mature milk while the estimated copper intake of infants was 210, 229 and 220 $\mu\textrm{g}$/day, respectively. The content of zinc in the milk was 5.24 $\mu\textrm{g}$/g in colostrum, 3.70 $\mu\textrm{g}$/g in transitional milk, 2.93 $\mu\textrm{g}$/g in mature milk while the estimated zinc intake of infants was 2452, 1968, and 1949 $\mu\textrm{g}$/day, respectively. These results suggest that copper and zinc intake of infants are met to RDA but iron is not.

• Korean Institute of Interior Design Journal
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• v.15 no.5 s.58
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• pp.193-201
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• 2006

In according as the social action of women is active, the average life span is longer than male, not only woman's social position is higher, but also the construction of the more professional woman special hospital Is increased. In occasion to the recent woman special hospital, give medical treatment about pediatrics and the breast surgery as well, and the sphere is increasing as compose the variety network, from the health medical center to check the woman's physical to the postpartum care center. The trend of the lobby is arranged the more service area as the concept of the woman hospital is changed, the sphere is increasing. Accordingly, this study research and analyze the service zone and design elements on the focus the lobby of the internal woman special hospital, have an intention of guideline about the interior design of the after woman hospital. As the subject of study, selected the hospital that lobby serves to show the identity of total space, and the woman special hospital that is introduced to the relation journal with architecture or interior design, is opened after 2000 years, below the 100 bed. As the study method, understand the composition of lobby space through floor analysis, examination by the visit, analyzed the arrangement constituent, the design trend. The direction of lobby space mentioned in the study result is that secure the publicness, guarantee the privacy zone, and is important that the adequate arrangement of commercial space contribute to client's mental stability, desire that inflected as the more positive communication place.

• The Journal of the Korea Contents Association
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• v.17 no.8
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• pp.366-381
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• 2017

This study was conducted in order to evaluate validity and reliability of the Korean version scale to measure maternal satisfaction in normal birth(KSMMS-normal birth). The SMMS-normal birth was administered to 205 postnatal women, together with the perception of birth experience scale. An exploratory factor analysis revealed six factors solution for the twenty three-item scale. Confirmatory factor analysis supported good convergent and discriminant validities, and factor correlations ranged from 0.11 to 0.57. The KSMMS-normal birth showed good concurrent validity with the perception of birth experience scale. The Cronbach alpha for the total scale was .91. It ranged between .80 to .90 for six subscales. The KSMMS-normal birth is reliable and valid instrument to measure maternal satisfaction. Therefore this scale can be used to assess maternal satisfaction in normal birth at hospital during the postpartum 2nd and 3rd day.

• Korean Journal of Social Welfare
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• v.65 no.2
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• pp.131-154
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• 2013

Although fatalities due to child abuse are frequently happened, there has been a dearth of research on the topic. The present research analyzes deaths due to child abuse in representative newspapers in order to examine incidences, causes, and characteristics of child abuse. The results showed that from 2000 to 2012 child abuse deaths occurred 141 cases. Most deaths due to child abuse were committed by single mothers, biological mothers, cohabiting women and stepmothers, and biological fathers. As regards the reasons of deaths due to child abuse, the frequency of newborn infant deaths as the result of abuse by single mother or single parent was the highest, and lack of parenting skills, postpartum depression, hardships of living and lack of financial abilities were followed. Also, subjects received extensive media coverage were crime compositions-stereotypes of child abusers, habitual and continual child abuse, lack of child abuse reporting and prevention system, and mild penalties. Finally, based on the results of the study, the implications to prevent and resolve deaths due to child abuse were discussed.

• Journal of Oriental Medical Thermology
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• v.8 no.1
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• pp.48-63
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• 2010

Purpose : Mothers and primary encounter and Korean traditional Gynecology clinician's perspective on breastfeeding, the importance and general knowledge, familiar with the breastfeeding-related issues to help resolve the maternal education and treatment. treatment options for a specific note down the need for Maternity and think that the existing studies and articles about breast diseases with reference to the view of the contemplated. Method : Maternity and breast disease with reference to research and review papers. Results : The first, from the past to encourage nursing mothers to eat a lot of nursing was given recently is changing the perception of adequate calories. and second, the posture of breastfeeding in prevention of mother's fatigue and pain and the baby's milk intake should be considered effective. The third, breast feeding is heavier than normal because of the surrounding muscle tissue in the breast to support the training may be helpful to. At last is emotional stability, and adequate nutritional intake and their milk is not enough awareness and interest in and education about breast-feeding mothers to breastfeed will help you look. Conclusion : Prenatal care program in order to facilitate breastfeeding and breast-feeding from the breast managed Postpartum Care Program consists of a map for the breast-related discomfort in advance to lead to prevention and to increase women's satisfaction seems to be.

• The Journal of Korean Obstetrics and Gynecology
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• v.32 no.3
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• pp.192-213
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• 2019

Objectives: The purpose of this study is to analyze the domestic study trends of pharmacopuncture therapy on obstetrics and gynecological diseases in Korean literature, through reviewing the clinical and experimental studies. Methods: We searched for clinical and experimental studies using pharmacopuncture therapy on obstetrics and gynecological diseases, published from January 2000 to May 2019, through 5 Korean databases. The study design, target disease, type of pharmacopuncture, method of intervention, and study results were analyzed. Results: 36 experimental studies and 15 clinical studies were finally included according to inclusion and exclusion criteria. In experimental studies, there were 12 studies about postmenopausal osteoporosis, 9 studies about obesity, 4 studies about endometriosis, 3 studies about hemostatic effects and analgesic anticoagulative effects, 2 studies about ovarian function, and analgesic antiphlogistic anticoagulative effects, and 1 study about menopausal symptoms. In clinical studies, there were 3 studies about obesity, postpartum disorders, dysmenorrhea, and women's urologic disease, and 1 study about menopausal symptoms, atypical squamous cells of undetermined significance (ASCUS) and breast cancer. Various types of pharmacopuncture have been proved to have a therapeutic effect in each of those obstetrics and gynecological diseases. Conclusions: This study indicates that pharmacopuncture therapy could be a good treatment for obstetrics and gynecological diseases. However, more well-designed and high-quality clinical researches are needed in further studies, to prove the effectiveness and safety of pharmacopuncture therapy.