• Carbon letters
• /
• v.27
• /
• pp.12-17
• /
• 2018

We fabricated a Li-S battery with post-treated carbon nanotube (CNT) films which offered better support for sulfur, and investigated the effect of the surface properties and pore structure of the post-treated CNT films on Li-S battery performance. Post-treatments, i.e., acid treatment, unzip process and cetyltrimethylammonium bromide (CTAB) treatment, effectively modified the surface properties and pore structure of the CNT film. The modified pore structure impacted the ability of the CNT films to accommodate the catholyte, resulting in an increase in initial discharge capacity.

• Journal of Pharmaceutical Investigation
• /
• v.36 no.6
• /
• pp.421-435
• /
• 2006

The objective of this report is to introduce the European Union's variation rules governing medicinal products that are subject to post-approval changes. The EMEA outlines a variety of changes occurring to approved medicinal products. It also recommends a marketing authorisation holder to follow specific post-approval applications in various situations. For instance, the Commission Regulation(EC) No. 1085/2003 explains variation types and suggests post-authorisation procedures with which an applicant should comply. In all cases of minor and major variations the applicant has to investigate and validate whether or not the intended changes would have impact on the safety, efficacy and quality of a drug product. The applicant should then submit to the EMEA a variation application with adequate documentation in support of the notified changes. This procedure is implemented to ensure that changes to the approved medicinal product do not cause my public health concerns. In fact, the post-authorisation guidance categorizes post-approval changes into type IA/IB variations, type II variations, and extension applications. Such classifications determine administrative procedures to be followed in an efficient manner. Based on the type of a variation, the regulatory agency opts to reduce or extend the evaluation time-frame. The thrust of the EU's post-authorisation guidance is introduced in text with appropriate explanation. All these information will be likely to be helpful in updating a Korean regulatory guidance that could better deal with post-approval changes to generic drugs available in the market.

• BMB Reports
• /
• v.44 no.3
• /
• pp.147-157
• /
• 2011

The meiotic process from the primordial stage to zygote in female germ cells is mainly adjusted by post-transcriptional regulation of pre-existing maternal mRNA and post-translational modification of proteins. Several key proteins such as the cell cycle regulator, Cdk1/cyclin B, are post-translationally modified for precise control of meiotic progression. The second messenger (cAMP), kinases (PKA, Akt, MAPK, Aurora A, CaMK II, etc), phosphatases (Cdc25, Cdc14), and other proteins (G-protein coupled receptor, phosphodiesterase) are directly or indirectly involved in this process. Many proteins, such as CPEB, maskin, eIF4E, eIF4G, 4E-BP, and 4E-T, post-transcriptionally regulate mRNA via binding to the cap structure at the 5' end of mRNA or its 3' untranslated region (UTR) to generate a closed-loop structure. The 3' UTR of the transcript is also implicated in post-transcriptional regulation through an association with proteins such as CPEB, CPSF, GLD-2, PARN, and Dazl to modulate poly(A) tail length. RNA interfering is a new regulatory mechanism of the amount of mRNA in the mouse oocyte. This review summarizes information about post-transcriptional and post-translational regulation during mouse oocyte meiotic maturation.

• Journal of Korean Society of Water and Wastewater
• /
• v.22 no.2
• /
• pp.213-218
• /
• 2008

Prediction models for post-chlorination require complicated information of reaction time, chlorine dosage considering flow rate as well as environmental conditions such as turbidity, temperature and pH. In order to operate post-chlorination process effectively, the correlations between inlet and outlet of clear well were investigated to develop prediction models of chlorine dosages in post-chlorination process. Correlations of environmental conditions including turbidity and chlorine dosage were investigated to predict residual chlorine at the outlet of clear well. A linear regression model and autoregressive model were developed to apply for the post-chlorination which take place time delay due to detention in clear well tank. The results from autoregressive model show the correlationship of 0.915~0.995. Consequently, the autoregressive model developed in this study would be applicable for real time control for post chlorination process. As a result, the autoregressive model for post chlorination which take place time delay and have multi parameters to control system would contribute to water treatment automation system by applying the process control algorithm.

• Language and Information
• /
• v.4 no.1
• /
• pp.110-120
• /
• 2000

• Fashion & Textile Research Journal
• /
• v.19 no.1
• /
• pp.19-29
• /
• 2017

This study identified the purchase decision-making process of outdoor wear consumers and examined the hypothesis that consumer satisfaction mediates the relationship between purchase decision-making process and repurchase intention. Data were acquired from a survey and analyzed with descriptive, factor analysis, reliability analysis and multiple regression analysis. Respondents were 454 adults who have purchased outdoor wear. The results are as follows. First, the purchase decision-making processes of outdoor wear consumers consisted of a series of steps: need recognition & passive information search, active information search, evaluation of alternatives with practical attributes, evaluation of alternatives with unpractical attributes, purchase decision, and post-purchase evaluation. Second, four purchase decision-making processes (except for need recognition & passive information search and active information search) had significantly positive effects on consumer satisfaction. Third, the need recognition & passive information search, the evaluation of alternatives with unpractical attributes and post-purchase evaluation had significantly positive effects on repurchase intention. Lastly, the partial mediation of consumer satisfaction in the relationship between two purchase decision-making processes (evaluation of alternatives with unpractical attributes and post-purchase evaluation) and repurchase intention were indicated. This academic study will help to understand the purchase decision-making processes of outdoor wear and allow companies to obtain information (from the industrial aspect) about which process to invest in and how to manage the process.

• Journal of Korean Academy of Nursing
• /
• v.42 no.3
• /
• pp.333-341
• /
• 2012

Purpose: The purpose of this study was to test whether pre-operative visual information and parental presence had positive effects on anxiety, delirium, and pain in pediatric patients who awoke from general anesthesia in a post-surgical stage. Methods: This study used a non equivalent control-group post test design (n=76). Independent variables were provision of pre-operative visual information and parental presence for post-surgical pediatric patients in PACU (post anesthesia care unit). Dependent variables were anxiety, delirium, and pain in the pediatric patients measured three times at 10 minute intervals after extubation in the PACU. Measurements included Numerical Rating Scale for assessing state anxiety, Pediatric Anesthesia Emergence Delirium Scale by Sikich & Lerman (2004) for delirium, and Objective Pain Scale by Broadman, Rice & Hannallah (1988) for pain. Results: Experimental group showed significantly decreased state anxiety at time points-10, 20, and 30 minutes after extubation. Delirium was significantly lower at 10 minutes and 30 minutes after extubation in the experimental group. Pain was significantly lower at 10 minutes after extubation in the experimental group. Conclusion: The results of this study suggest that this intervention can be a safe pre-operative nursing intervention for post-surgical pediatric patients at PACU.

• 한국공간정보시스템학회:학술대회논문집
• /
• 2004.05a
• /
• pp.37-42
• /
• 2004

The primary objective of this paper is to trace the post-buckling behavior of space trusses in the inelastic range. Modeled member material behavior characteristics of struts in the post-critical elasto-plastic stage are determined and three types of idealized hardening rules are described. To perform this analysis, the present work is used the current stiffness parameter method combined with the cylinderical arc-length method. Numerical examples are presented to illustrate the accuracy and the application of the numerical solutions introduced above.

• Proceedings of the Korea Society for Industrial Systems Conference
• /
• 2008.10b
• /
• pp.194-198
• /
• 2008

Under the rapid change of business circumstance to E-business, CRM is one of the major strategic choices to reinforce the relationship with customers. In this point, this study attempts to understand the relationships among the quality of CRM and the variables of post adoption on the innovation diffusion theory. With integration of information system success model and innovation diffusion theory, it developed a research model and several hypotheses focusing on CRM performance of post-adoption. To testify the hypotheses, it conducted a survey on insurance industry and performed a statistical analysis for the research model with structure equation model. The results show that the factors of CRM quality (system, service, and information) have significant relationships with level of CRM usage and satisfaction. And the relationships between satisfaction and CRM performance and between CRM performance and intension of CRM extension are found as statistically significant.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2009.11a
• /
• pp.345-346
• /
• 2009

The segmentation of vessel including portal vein, hepatic vein and artery, from Computed Tomography (CT) images plays an important role in the therapeutic strategies for hepatic diseases. Representing segmented vessels in three dimensional spaces is extremely useful for doctors to plan liver surgery. In this paper, proposed method is focused on smoothing technique of segmented 3D liver vessels, which derived from 3D region growing approach. A pixel expand algorithm has been developed first to avoid vessel lose and disconnection cased by the next smoothing technique. And then a binary volume filtering technique has been implemented and applied to make the segmented binary vessel volume qualitatively smoother. This strategy uses an iterative relaxation process to extract isosurfaces from binary volumes while retaining anatomical structure and important features in the volume. Hard and irregular place in volume image has been eliminated as shown in the result part, which also demonstrated that proposed method is a suitable smoothing solution for post processing of fine vessel segmentation.