• Journal of the East Asian Society of Dietary Life
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• v.6 no.1
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• pp.105-114
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• 1996

Certain Fungi Including Aspergillus flavus produce low molecular secondary metabolite that is toxic to human and animals, which have been termed mycotoxin. Given the proper humidity and temperature like summer in Korea, are capable of growing of those hazard fungi and elaborating mycotoxin on almost any organic substrate such as traditional foodstuffs and their raw materials including rice, barley, corn, meju, doenjang and gochujang etc. Until now, some people have examined to isolate various fungi such as Aspergillus sp., Penicillium sp. and Fusarium sp. from traditional foodstuffs and raw materials, and have screened various mycotoxin producing strains. Some mycotoxin contamination such as aflatoxin, ochratoxin, deoxynivalenol (DON) and zearalenone etc. also have been confirmed from similar above samples. But these data are different each other and inconsistent in experimental conditions and methods. Especially, almost experiments have been finished for one time. So more consistent experimental method and data are necessary to evaluate objectiely the safety of traditional foodstuffs subjected to the mycotoxin. For this purpose, we have to apply a new advanced technology to develop more simple and rapid methods for determination of mycotoxin and also have to concentrate our efforts on activation of research and accumulation of technology nth sustaining investment of financial support and enlargement of research installation. With those harmonious efforts, it should be possible to examine continuously nd systematically the mycotoxin contamination in our traditional foodstuffs and to assure the safety of them. Then we can maintain and develop the better traditional foodstuffs suited to internationalization.

• Journal of Breast Cancer
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• v.21 no.4
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• pp.382-390
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• 2018

Purpose: PIK3CA mutation is considered to be a possible cause for resistance to neoadjuvant chemotherapy (NAC) in human epidermal growth factor receptor 2 (HER2)-positive breast cancer. We investigated the association between PIK3CA mutations and the outcome of NAC in HER2-positive breast cancers. Methods: A total of 100 HER2-positive breast cancer patients who had undergone NAC and surgery between 2004 and 2016 were examined. Mutation status was sequentially assessed in pre-NAC, post-NAC, and recurrent specimens taken from these patients. Results: PIK3CA mutations were identified in the sequential specimens of 17 patients (17.0%). These 17 patients experienced shorter disease-free survival (DFS) than the rest of the patients (58.3 months vs. 119.3 months, p=0.020); however, there was no significant difference in pathologic complete response (pCR) and overall survival (OS) (pCR, 17.6% vs. 33.7%, p=0.191; OS, 84.5 months vs. 118.0 months, p=0.984). While there was no difference in pCR between the wild-type and mutant PIK3CA groups in pre-NAC specimens (25.0% vs. 31.8%, p=0.199), PIK3CA mutations correlated with lower pCR in postNAC specimens (0.0% vs. 24.3%, p<0.001). Multivariate analysis revealed significantly worse DFS in the mutant PIK3CA group than in the wild-type group (hazard ratio, 3.540; 95% confidence interval, 1.001-12.589; p=0.050). Moreover, the DFS curves of the change of PIK3CA mutation status in sequential specimens were significantly different (p=0.016). Conclusion: PIK3CA mutation in HER2-positive breast cancer was correlated with a lower pCR rate and shorter DFS. These results suggest that PIK3CA mutation is a prognostic marker for NAC in HER2-positive breast cancer, especially in post-NAC specimens.

• The Journal of Society for e-Business Studies
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• v.23 no.3
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• pp.159-171
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• 2018

The imported foods, which are imported and sold domestically, are on the rise every year, and the scale is expected to be larger, including processing the imported raw materials. However, the origin of raw materials is indicated when declaring cargo for finished products of agricultural products, but the standardization of inspection information management system for raw materials is insufficient. In addition, there is a growing concern about the presence of residual pesticides or radioactivity in raw materials or products, and customer want to know production history information when purchasing agrifoods. It manages the hazard analysis of imported agricultural products, but most of them are global issues such as microorganisms, residual pesticides, food additives, and allergy components, etc. Therefore, it is necessary to share among the logistics entities in the entire transportation process the related data. Additionally, to do this, it needs to design an architecture and standardize business model. In this paper, it defines the architecture and the work-flow that occurs between the business process for collecting, processing, and processing information for tracking the status of imported agricultural products by steps, and develops XML message with UBL and the extracted conceptual information model. It will be easy to exchange and share information among the logistics entities through the defined standard model and it will be possible to establish visibility, reliability, safety, and freshness system for transportation of agricultural products requiring real-time management.

• The Journal of Engineering Geology
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• v.29 no.1
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• pp.13-21
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• 2019

The rainfall intensity-duration curve (I-D curve) was used for selecting the dredging time of sediments behind a debris barrier which is located at the study area in Inje-gun, Kangwon Province. The I-D curve was newly suggested by using the data of rainfall-induced landslides for about 30 years from June to September in Kangwon Province. According to the monitoring results, the landslides have been not occurred during the monitoring period of the dredged sediments management system at the study area, and also all of the rainfall events were located below the I-D curve. The weight of the dredged sediments measured at the management system in the field was increased but the weight increment was small. It means that the increase of the dredged sediments was not the effect of landslide but the effect of soil erosion at the ground surface due to heavy rainfall. The weight of the dredged sediments behind a debris barrier could be known in real time using the rainfall data measured at the management system. Also, when the I-D curve is used with the management system, it is possible to select the optimum dredging time for sediments behind debris barrier.

• Journal of the Korean Society of Safety
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• v.34 no.4
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• pp.22-31
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• 2019

The flammable liquid conductivity is an important factor in determining the generation of electrostatic in fire and explosion hazardous areas, so it is necessary to study the physical properties of flammable liquids. In particular, the relevant liquid conductivity in the process of handling flammable liquids in relation to the risk assessment and risk control in fire and explosion hazard areas, such as chemical plants, is classified as a main evaluation item according to the IEC standard, and it is necessary to have flammable liquid conductivity measuring devices and related data are required depending on the handling conditions of the material, such as temperature and mixing ratio for preventing the fire and explosion related to electrostatic. In addition, IEC 60079-32-2 [Explosive Atmospheres-Part 32-2 (Electrostatic hazards-Tests)] refers to the measuring device standard and the conductivity of a single substance. It was concluded that there is no measurement data according to the handling conditions such as mixing ratio of flammable liquid and temperature together with the use and measurement examples. We have developed the measurement reliability by improving the structure, material and measurement method of measuring device by referring to the IEC standard. We have developed a measurement device that is developed and manufactured by itself. The test results of flammable liquid conductivity measurement and the data of the NFPA 77 (Recommended Practice on Static Electricity) Annex B Table B.2 Static Electric Characteristic of Liquids were compared and verified by conducting the conductivity measurement of the flammable liquid handled in the fire and explosion hazardous place by using Measuring / Data Acquisition / Processing / PC Communication. It will contribute to the prevention of static electricity related disaster by taking preliminary measures for fire and explosion prevention by providing technical guidance for static electricity risk assessment and risk control through flammable liquid conductivity measurement experiment. In addition, based on the experimental results, it is possible to create a big data base by constructing electrostatic physical characteristic data of flammable liquids by process and material. Also, it is analyzed that it will contribute to the foundation composition for adding the specific information of conductivity of flammable liquid to the physical and chemical characteristics of MSDS.

• Journal of the Korean Institute of Gas
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• v.26 no.3
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• pp.27-37
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• 2022

With the recent increase in the spread of ESS (Electric Storage System), the damage to human life and property is also rapidly increasing due to continuous fires caused by ESS. In the manufacture of urethane sandwich panels used in ESS, it is necessary to improve the flame retardant performance. In this study, in order to realize the flame retardant properties of flexible polyurethane foam, the effect of the tissue density of the product due to the change of the isocyanate functional group parameter that changes the physical properties of the product on the fire performance was studied. The product was manufactured by changing the density of the urethane structure, and combustion performance tests, gas toxicity tests, and smoke density tests were performed. As a result, it was confirmed that the total amount of heat released had excellent performance when the isocyanate functional group was high, and had no correlation with the maximum heat release rate. When the value of the isocyanate functional group was 2.7 or more, the collapse of the shape could be prevented. In the gas hazard test, the performance was increased when the isocyanate functional group was relatively high, so a flame retardant for the Char system, which had a dense structure and easy to form a carbonized film, was added. confirmed to be. Therefore, as a result of this study, it is thought that it will be possible to lay the foundation for the development of a flame retardant to replace the cheap urethane sandwich panel used in the past.

• Journal of Navigation and Port Research
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• v.46 no.1
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• pp.57-72
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• 2022

The recent increase in international trade volume and explosive increase in cargo volume due to the non-face-to-face society are leading to an increase in risk exposure and safety accidents in the port logistics industry. Consequently, as the atmosphere and consensus on safety are spreading throughout the society, various safety laws are being enacted by the industry. Nevertheless, according to the industrial accidents status analysis by the Ministry of Employment and Labor, the average annual number of injured persons increased by 11.1% and the number of deaths by 4.0% from 2015 to 2019. This means that special attention should be paid to possible future risks and preventive measures for major causes of accidents should be established. Therefore, in this study, risk assessment was conducted based on 5,028 accident cases that were reported by the Korea Occupational Safety and Health Agency for 5 years, from 2016 to 2020, and major risk factors for each industry were derived, and then bow-tie analysis was conducted to perform the risk assessment; Further, the study aimed to derive the causes and preventive measures from the risk factors.

• Resources Recycling
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• v.32 no.3
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• pp.3-8
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• 2023

This study discussed production, demand, and future prospects of rubidium, which is an alkali group metal that is highly reactive to various media and requires carefulness in handling, but no significant environmental hazard of rubidium has been reported yet. Rubidium is used in various fields such as optoelectronic equipment, biomedical, and chemical industries. Because of difficulty in production as well as limited demand, the transaction price of rubidium is relatively high, but its detail information such as market status and potential growth is uncertain. However, if the mass production of versatile ultra-high-performance equipment such as quantum computers and the necessity of rubidium use in the equipment are confirmed, there is a possibility that the rubidium market will expand in the future. Rubidium is often found together with lithium, beryllium, and cesium, and may be present in granite containing minerals such as lepidolite and pollucite, as well as in seawater and industrial waste. Several technologies such as acid leaching, roasting, solvent extraction, and adsorption are used to recover rubidium. The maximum recovery efficiency of the rubidium from the sources and the processing above is generally high, but, in many practices, rubidium is not the main recovery target, and therefore the actual recovery effects should depend on presence of other valuable components or impurities, together with recovery costs, energy consumption, environmental issues, etc. In conclusion, although the current production and consumption of rubidium are limited, with consideration of the possible market fluctuations according to the emergence of large-scale demand sources, etc., further investigations by related institutions should be necessary.

• Journal of the Korean Society of Marine Environment & Safety
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• v.29 no.7
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• pp.964-970
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• 2023

As part of the International Maritime Organization ef orts to reduce greenhouse gas emissions, the maritime industry is exploring low-carbon fuels such as liquefied natural gas and methanol, as well as zero-carbon fuels such as hydrogen and ammonia, evaluating them as environmentally friendly alternatives. Particularly, ammonia has substantial operational experience as cargo on transport ships, and ammonia ship engines are expected to be available in the second half of 2024, making it relatively accessible for commercial use. However, overcoming the toxicity challenges associated with using ammonia as a fuel is imperative. Detection is possible at levels as low as 5 ppm through olfactory senses, and exposure to concentrations exceeding 300 ppm for more than 30 min can result in irreparable harm. Using the KORA program provided by the Chemical Safety Agency, an assessment of the potential risks arising from leaks during ammonia bunkering was conducted. A 1-min leak could lead to a 5 ppm impact within a radius of approximately 7.5 km, affecting key areas in Busan, a major city. Furthermore, the potentially lethal concentration of 300 ppm could have severe consequences in densely populated areas and schools near the bunkering site. Therefore, given the absence of regulations related to ammonia bunkering, the potential for widespread toxicity from even minor leaks highlights the requirement for the development of legislation. Establishing an integrated system involving local governments, fire departments, and environmental agencies is crucial for addressing the potential impacts and ensuring the safety of ammonia bunkering operations.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.43 no.6
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• pp.699-708
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• 2023

Nuclear power plants (NPPs) consider possible external events, including natural hazards, during the design phase to ensure safe operation. However, in recent years, due to the increasing probability of natural hazards exceeding the design, a careful review of extreme natural hazards and unforeseen external events during the design phase has become necessary. In this study, the objective was to screen potential extreme natural hazards at NPP sites in Korea. Initially, we investigated and analyzed the characteristics of NPP sites and the events caused by external hazards. Furthermore, we analyzed existing literature and research data to establish screening procedures and criteria that suit the actual conditions of domestic NPPs. Based on these criteria and data, we conducted qualitative screening for each NPP site and identified potential extreme natural hazards through quantitative screening and walkdown. As a result of the screening, in addition to internal flooding caused by heavy rain, wind pressure and extreme air pressure caused by extreme winds were screened as potential extreme natural hazards common to all sites. Additionally, at the Kori site, storm surge was selected as the most significant potential extreme natural hazard.