• Title/Summary/Keyword: positive feature

Search Result 449, Processing Time 0.025 seconds

Myxofibrosarcoma Originating from Chest Wall (흉벽에서 발생한 점액성섬유육종)

  • Cha, Byung-Ki;Lee, Mi-Kyung;Lee, Sam-Youn;Choi, Chong-Bum;Choi, Soon-Ho
    • Journal of Chest Surgery
    • /
    • v.39 no.2 s.259
    • /
    • pp.166-170
    • /
    • 2006
  • Myxofibrosarcoma represents one of the most common soft tissue sarcomas of the extremities in adult and elderly patients. However, it only rarely occurs in the chest wall. A 58 years old woman presented with a huge painless lump (8 ${\times}$ 6.5 cm) in the right lower parasternal area which recurred a few months following excision from General surgery of our hospital. Histology showed an infiltrative deep seated dermal and subcutaneous tumor. It had a distinctive lobular growth pattern with prominent myxoid change and moderate cellularity. Tumor cells were spindleshaped with varying degrees of pleomorphism and frequent mitotic figures. Numerous blood vessels with curvilinear growth pattern were also seen. Immunostains for S-100, CD68, Mac 387, and FX IIIa were all negative, but positive for Vimentin. The histologic feature was of an intermediate grade myxofibrosarcoma. Wide excision was performed and recovered in good condition without any physical disabilities and was discharged at one month later. Currently she is waiting for the skin graft without chemotherapy and radiotherapy.

Feasibility study of a dedicated nuclear desalination system: Low-pressure Inherent heat sink Nuclear Desalination plant (LIND)

  • Kim, Ho Sik;NO, Hee Cheon;Jo, YuGwon;Wibisono, Andhika Feri;Park, Byung Ha;Choi, Jinyoung;Lee, Jeong Ik;Jeong, Yong Hoon;Cho, Nam Zin
    • Nuclear Engineering and Technology
    • /
    • v.47 no.3
    • /
    • pp.293-305
    • /
    • 2015
  • In this paper, we suggest the conceptual design of a water-cooled reactor system for a low-pressure inherent heat sink nuclear desalination plant (LIND) that applies the safety-related design concepts of high temperature gas-cooled reactors to a water-cooled reactor for inherent and passive safety features. Through a scoping analysis, we found that the current LIND design satisfied several essential thermal-hydraulic and neutronic design requirements. In a thermal-hydraulic analysis using an analytical method based on the Wooton-Epstein correlation, we checked the possibility of safely removing decay heat through the steel containment even if all the active safety systems failed. In a neutronic analysis using the Monte Carlo N-particle transport code, we estimated a cycle length of approximately 6 years under 200 $MW_{th}$ and 4.5% enrichment. The very long cycle length and simple safety features minimize the burdens from the operation, maintenance, and spent-fuel management, with a positive impact on the economic feasibility. Finally, because a nuclear reactor should not be directly coupled to a desalination system to prevent the leakage of radioactive material into the desalinated water, three types of intermediate systems were studied: a steam producing system, a hot water system, and an organic Rankine cycle system.

A study to Explore the Effect Relationship of Character and Life Goal on Happiness for Gifted Elementary Students in Science (초등과학영재학생의 인성, 생애목표와 행복감의 관계)

  • Chang, Heesun
    • Journal of Gifted/Talented Education
    • /
    • v.26 no.1
    • /
    • pp.161-185
    • /
    • 2016
  • The purpose of this study was to investigate for gifted elementary students in science the feature of character, life goals and happiness, and the effect relationship on happiness based on the relationship between factors. For this, independent t-test, multi-linear regression analysis and hierarchical regression were conducted. The results from this study are as follows. First, scientifically gifted elementary students show higher level of responsibility, ethics, positive self-understanding and contribution goal, but lower in material and image goal than general students. Second, character, life goal and happiness are correlated. Third, female students rather than male students and students with consideration/service character have intrinsic goals. While, the students with higher level of consideration/service and lower level of sympathy show extrinsic goals. The higher the level of consideration/service and the lower of self-control they have the higher their happiness are. Fourth, as scientifically gifted elementary students have more consideration and relationship goal, their happiness go up. While, the more they have self-growth and material goal, the lower the happiness. Fifth, the character of scientifically gifted elementary students is the factor that explains the effect on happiness more easily than life goal, relatively. The factor of life goal mediates the consideration/service and happiness. In conclusion, I hope that this study contribute to raise the happiness of scientifically gifted elementary students, and considerate the character education and counseling program for character development.

The Attitude towards Nature According to Awareness of the Natural Monuments -Focusing on Natural Monuments in Naejang National Park- (천연기념물 인식수준에 따른 자연에 대한 태도 차이)

  • Son, Ji-Won;Shin, Jin-Ho;Jeon, Yong-Sam
    • Korean Journal of Environment and Ecology
    • /
    • v.29 no.6
    • /
    • pp.959-966
    • /
    • 2015
  • A natural monument is designated and protected as a natural or natural/cultural feature of outstanding or unique value because of its aesthetic qualities or cultural significance. However, in recent years, a natural monument plays a role in satisfying the cultural desire of people. For this reason, the main purpose of this study was to investigate public awareness of natural monuments and to evaluate the attitudes towards nature the visitors to Naejang national park displayed. This study also examined the differences in visitors' level of attitudes towards nature according to their awareness of natural monuments. Population of Macropodous Daphniphyllum (Natural Monument No. 91) and Forest of Japanese Torreyas at Baegyangsa Temple, Jangseong (Natural Monument No. 153) are present in large numbers in Naejang national park. For the research, 240 Naejang national park visitors were surveyed to collect data. Results of this study indicated that fewer than 50% of visitors displayed an appropriate awareness of natural monuments. There were also significant differences in attitudes towards nature according to visitors' awareness of natural monuments. In particular, visitors' awareness of the population of Macropodous Daphniphyllum was relatively lower when compared to that on Forest of Japanese Torreyas at Baegyangsa Temple. In addition, visitors who had a high level of awareness about natural monuments and thought that natural monuments had high cultural value displayed more positive attitudes than those who didn't have good levels of awareness. Based on these findings, this study suggests policy changes to establish development plans of the natural monuments in this area.

Product Review Data and Sentiment Analytical Processing Modeling (상품 리뷰 데이터와 감성 분석 처리 모델링)

  • Yeon, Jong-Heum;Lee, Dong-Joo;Shim, Jun-Ho;Lee, Sang-Goo
    • The Journal of Society for e-Business Studies
    • /
    • v.16 no.4
    • /
    • pp.125-137
    • /
    • 2011
  • Product reviews in online shopping sites can serve as a useful guideline to buying decisions of customers. However, due to the massive amount of such reviews, it is almost impossible for users to read all the product reviews. For this reason, e-commerce sites provide users with useful reviews or statistics of ratings on products that are manually chosen or calculated. Opinion mining or sentiment analysis is a study on automating above process that involves firstly analyzing users' reviews on a product to tell if a review contains positive or negative feedback, and secondly, providing a summarized report of users' opinions. Previous researches focus on either providing polarity of a user's opinion or summarizing user's opinion on a feature of a product that result in relatively low usage of information that a user review contains. Actual user reviews contains not only mere assessment of a product, but also dissatisfaction and flaws of a product that a user experiences. There are increasing needs for effective analysis on such criteria to help users on their decision-making process. This paper proposes a model that stores various types of user reviews in a data warehouse, and analyzes integrated reviews dynamically. Also, we analyze reviews of an online application shopping site with the proposed model.

Pharmacophore Mapping and Virtual Screening for SIRT1 Activators

  • Sakkiah, Sugunadevi;Krishnamoorthy, Navaneethakrishnan;Gajendrarao, Poornima;Thangapandian, Sundarapandian;Lee, Yun-O;Kim, Song-Mi;Suh, Jung-Keun;Kim, Hyong-Ha;Lee, Keun-Woo
    • Bulletin of the Korean Chemical Society
    • /
    • v.30 no.5
    • /
    • pp.1152-1156
    • /
    • 2009
  • Silent information regulator 2 (Sir2) or sirtuins are NAD(+)-dependent deacetylases, which hydrolyze the acetyllysine residues. In mammals, sirtuins are classified into seven different classes (SIRT1-7). SIRT1 was reported to be involved in age related disorders like obesity, metabolic syndrome, type II diabetes mellitus and Parkinson’s disease. Activation of SIRT1 is one of the promising approaches to treat these age related diseases. In this study, we have used HipHop module of CATALYST to identify a series of pharmacophore models to screen SIRT1 enhancing molecules. Three molecules from Sirtris Pharmaceuticals were selected as training set and 607 sirtuin activator molecules were used as test set. Five different hypotheses were developed and then validated using the training set and the test set. The results showed that the best pharmacophore model has four features, ring aromatic, positive ionization and two hydrogen-bond acceptors. The best hypothesis from our study, Hypo2, screened high number of active molecules from the test set. Thus, we suggest that this four feature pharmacophore model could be helpful to screen novel SIRT1 activator molecules. Hypo2-virtual screening against Maybridge database reveals seven molecules, which contains all the critical features. Moreover, two new scaffolds were identified from this study. These scaffolds may be a potent lead for the SIRT1 activation.

Influence of Social Support and Social Network on Quality of Life among the Elderly in a Local Community (지역사회 거주 일반노인의 사회적지지, 사회적관계망이 삶의 질에 미치는 영향)

  • Kim, Hyeong-Min;Sim, Kyoung-Bo;Kim, Hwan;Kim, Souk-Boum
    • The Journal of Korean society of community based occupational therapy
    • /
    • v.3 no.1
    • /
    • pp.11-20
    • /
    • 2013
  • Objective : The purpose of this study is to identify the impact of the social support and social network on the quality of life of the elderly residing in a local community. Method : The subjects of this study were 75 healthy old men and women of 13 sites of welfare centers for the disabled and public health centers and senior welfare centers in Busan and Gyeongju. A survey was conducted with a questionnaire that include general characteristics, cognitive ability, social support, social network and quality of life. The analysis was made on 63 replies except 12 subjects who had been excluded by the subject selection criteria. Result : As a result of analyzing correlation of variables affecting life quality, there was positive correlation in contact frequency(p<.05), intimacy(p<.001), and social support(p<.001). Finally, it was analyzed that the variable of intimacy (p<.001) affected life quality of general aged people living in regional community. Conclusion : It was found that intimacy of general aged people living in regional community was a major variable to affect life quality. It could be identified that intimacy which is qualitative feature of social, relational network for the aged who live passive life was important.

  • PDF

Quantitative Ultrastructural Analysis of Endings Presynaptic to the Tooth Pulp Afferent Terminals in the Trigeminal Oral Nucleus

  • Lee, Suk-Ki;Kim, Tae Heon;Lee, Cheon-Hee;Park, Sook Kyung;Bae, Yong Chul
    • International Journal of Oral Biology
    • /
    • v.41 no.3
    • /
    • pp.133-139
    • /
    • 2016
  • The ultrastructural parameters related to synaptic release of endings which are presynaptic to tooth pulp afferent terminals (p-endings) were analyzed to understand the underlying mechanism for presynaptic modulation of tooth pulp afferents. Tooth pulp afferents were labelled by applying wheat-germ agglutinin conjugated horseradish peroxidase to the rat right lower incisor, whereafter electron microscopic morphometric analysis with serial section and reconstruction of p-endings in the trigeminal oral nucleus was performed. The results obtained from 15 p-endings presynaptic to 11 labeled tooth pulp afferent terminals were as follows. P-endings contained pleomorphic vesicles and made symmetrical synaptic contacts with labeled terminals. The p-endings showed small synaptic release-related ultrastructural parameters: volume, $0.82{\pm}0.45{\mu}m^3$ ($mean{\pm}SD$); surface area, $4.50{\pm}1.76{\mu}m^2$; mitochondrial volume, $0.15{\pm}0.07{\mu}m^3$; total apposed surface area, $0.69{\pm}0.24{\mu}m^2$; active zone area, $0.10{\pm}0.04{\mu}m^2$; total vesicle number, $1045{\pm}668.86$; and vesicle density, $1677{\pm}684/{\mu}m^2$. The volume of the p-endings showed strong positive correlation with the following parameters: surface area (r=0.97, P<0.01), mitochondrial volume (r=0.56, P<0.05), and total vesicle number (r=0.73, P<0.05). However, the volume of p-endings did not positively correlate or was very weakly correlated with the apposed surface area (r=-0.12, P=0.675) and active zone area (r=0.46, P=0.084). These results show that some synaptic release-related ultrastructural parameters of p-endings on the tooth pulp afferent terminals follow the "size principle" of Pierce and Mendell (1993) in the trigeminal nucleus oralis, but other parameters do not. Our findings may demonstrate a characteristic feature of synaptic release associated with p-endings.

Fire Detection Approach using Robust Moving-Region Detection and Effective Texture Features of Fire (강인한 움직임 영역 검출과 화재의 효과적인 텍스처 특징을 이용한 화재 감지 방법)

  • Nguyen, Truc Kim Thi;Kang, Myeongsu;Kim, Cheol-Hong;Kim, Jong-Myon
    • Journal of the Korea Society of Computer and Information
    • /
    • v.18 no.6
    • /
    • pp.21-28
    • /
    • 2013
  • This paper proposes an effective fire detection approach that includes the following multiple heterogeneous algorithms: moving region detection using grey level histograms, color segmentation using fuzzy c-means clustering (FCM), feature extraction using a grey level co-occurrence matrix (GLCM), and fire classification using support vector machine (SVM). The proposed approach determines the optimal threshold values based on grey level histograms in order to detect moving regions, and then performs color segmentation in the CIE LAB color space by applying the FCM. These steps help to specify candidate regions of fire. We then extract features of fire using the GLCM and these features are used as inputs of SVM to classify fire or non-fire. We evaluate the proposed approach by comparing it with two state-of-the-art fire detection algorithms in terms of the fire detection rate (or percentages of true positive, PTP) and the false fire detection rate (or percentages of true negative, PTN). Experimental results indicated that the proposed approach outperformed conventional fire detection algorithms by yielding 97.94% for PTP and 4.63% for PTN, respectively.

Empowerment Effects of the Chronic Mental Ill's Volunteer Program (정신장애인 자원봉사 프로그램의 임파워먼트 효과)

  • Choi, Myung-Min
    • Korean Journal of Social Welfare
    • /
    • v.56 no.3
    • /
    • pp.89-112
    • /
    • 2004
  • The purpose of this study is to systemize volunteer program for the people with chronic mental health problems to participate in helping the community as service providers not receivers, and then to examine empowerment effects of this volunteer program. The distinctive feature of this program was to volunteer the mental ill to help other people. Therefore, this volunteer program had specially strengthened preliminary stage which make not only the mental ill be ready to work but also the community to use them as volunteer, and to invite general citizen of the community as co-volunteers. The result showed this program empowered the mental disorders to have more positive self-concept. It revealed that co-volunteer's attitude toward the mental disorders was changed positively through this program, also. These results told us not only the chronic mental ill could be volunteers helping others using their abilities, but also this activity would make their self-image better and citizen's perception toward mental disorder less prejudiced. The volunteer program presented in this paper was expected to be useful for their empowerment and social integration.

  • PDF