• Biomedical Science Letters
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• v.6 no.1
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• pp.11-17
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• 2000

SNAP-25 was first investigated as a neuron-specific protein preferentially expressed in CA3 pyramidal neurons of mouse hippocampus. It is a presynaptic plasma membrane protein in the nerve cell and plays an important role in the synaptic vesicle membrane docking and fusion pathway. We have recently isolated SNAP-25 cDNA from a rat brain cDNA library using a probe of Z2 cDNA. It consisted of 2,101 bp and an open reading frame (ORF) was identified between nucleotides (nt) 209 and 827. The AUG codon (nt 209∼211) was surrounded by CTACCATGG, which corresponded to the consensus sequence of ribosomal binding site. The ORF was terminated by TAA (nt 827∼829) to encode a polypeptide of 206 amino acid residues. The 3'-untranslated region contained two extensive stretches of repeated (CA)28 and (CA)19 at positions 925∼980 and 1645∼1682. It is noteworthy that cysteine residues were clustered in the span of amino acid residues 84∼991 : Cys-Gly-Leu-Cys-Val-Cys-Pro-Cys. Rat SNAP-25 showed 88% and 97% identity in nucleotide sequences to that of human and mouse, respectively. Amino acid sequence of rat SNAP-25 showed 100% identity to that of mouse and human SNAP-21.

• Progress in Medical Physics
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• v.27 no.3
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• pp.156-161
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• 2016

When air discharged from a radioisotope production facility is contaminated with radiation, the public may be exposed to radiation. The objective of this study is to manage such radiation exposure. We measured the airborne radioactivity concentration at a 30 MeV cyclotron radioisotope production facility to assess whether the exhaust gas was contaminated. Additionally, we investigted the radioactive contamination of the air filter for efficient air purification and radiation safety control. To measure the airborne radiation concentration, specimens were collected weekly for 4 h after the beginning of the radioisotope production. Regarding the air purifier, five specimens were collected at different positions of each filter-pre-filter, high-efficiency particulate air filter, and charcoal filter-installed in the cyclotron production room. The concentrations of F-18, I-123, I-131, and Tl-201 generated in the radioiodine production room were $13.5Bq/m^3$, $27.0Bq/m^3$, $0.10Bq/m^3$, and $11.5Bq/m^3$, respectively; the concentrations of F-18, I-123, and I-131 produced in the radioisotope production room were $0.05Bq/m^3$, $16.1Bq/m^3$, and $0.45Bq/m^3$, correspondingly; and those of F-18, I-123, I-131, and Tl-201 generated in the accelerator room were $2.07Bq/m^3$, $53.0Bq/m^3$, $0.37Bq/m^3$, and $0.15Bq/m^3$, respectively. The maximum radiation concentration of I-123 generated in the radioiodine production room was 1,820 Bq/g, which can be disposed after 2 days. The maximum radiation concentration of Tl-202 generated in the radioisotope production room was 205 Bq/g, and this isotope must be stored for 53 days. The I-123 generated in the radioiodine production room had a maximum concentration of 1,530 Bq/g and must be stored for 2 days. The maximum radiation concentration of Na-22 generated in the radioisotope production room was 0.18 Bq/g and this isotope must be disposed after 827 days. To manage the exhaust, the efficiency of air purification must be enhanced by selecting an air purifier with a long life and determining the appropriate replacement time by examining the differential pressure through systematic measurements of the airborne radiation contamination level.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.40 no.3
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• pp.127-138
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• 2016

Diesel vehicles should be equipped with urea-selective catalytic reduction(SCR) system as a high-performance catalyst, in order to reduce harmful nitrogen oxide emissions. In this study, a three-dimensional Eulerian-Lagrangian CFD analysis was used to numerically predict the multiphase flow characteristics of the urea-SCR system, coupled with the chemical reactions of the system's transport phenomena. Then, the numerical spray structure was modified by comparing the results with the measured values from spray visualization, such as the injection velocity, penentration length, spray radius, and sauter mean diameter. In addition, the analysis results were verified by comparison with the removal efficiency of the nitrogen oxide emissions during engine and chassis tests, resulting in accuracy of the relative error of less than 5%. Finally, a verified CFD analysis was used to calculate the interanl flow of the urea-SCR system, thereby analyzing the characteristics of pressure drop and velocity increase, and predicting the uniformity index and overdistribution positions of ammonia.

• Journal of Korea Water Resources Association
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• v.49 no.1
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• pp.19-28
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• 2016

The objective of this study is the generation of the gridded flash flood index using the gridded hydrologic components of TOPLATS land surface model and statistic flash flood index model. The accuracy of this method is also examined in this study. The study area is the national capital region of Korea, and 38 flash flood damages had occurred from 2009 to 2012. The spatio-temporal resolutions of land surface model are 1 h and 1 km, respectively. The gridded meteorological data are generated using the inverse distance weight method with automatic weather stations (AWSs) of Korea Meteorological Administration (KMA). The hydrological components (e.g., surface runoff, soil water contents, and water table depth) of cells corresponding to the positions of 38 flood damages reasonably respond to the cell based hourly rainfalls. Under the total rainfall condition, the gridded flash flood index shows 71% to 87% from 4 h to 6 h in the lead time based on the rescue request time and 42% to 52% of accuracy at 0 h which means that the time period of the lead time is in a limited rescue request time. From these results, it is known that the gridded flash flood index using the cell based hydrological components from land surface model and the statistic flash flood index model have a capability to predict flash flood in the mountainous area.

• Journal of the Mineralogical Society of Korea
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• v.13 no.3
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• pp.164-170
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• 2000

Neutron single crystal and powder diffraction techniques have been applied to the structure analysis of yttria-stabilized zirconium, Z $r_{0.73}$ $Y_{0.27}$ $O_{1.87}$., prepared by the skull-melting method. The crystal structure has been determined to be cubic symmetry, space group Fm/equation omitted/ with a=5.155(2)$\AA$, V=136.99(5)$\AA$, Z=4, and R(F)=5.65%, $\omega$R(I)=10.57% for 70 integrated intensities of Bragg Peaks observed from single crystal of Z $r_{0.73}$ $Y_{0.27}$ $O_{1.87}$. The stabilizer atoms randomly occupy the zirconium sites and there are displacements of oxygen atoms with amplitudes of $\Delta$/a~0.033 and 0.11 along <110> and <100> directions from the ideal positions of the fluorite structure, respectively. There are no significant differences in crystallographic data between the single crystal and powder studies. Diffraction pattern after Rietveld refinement, using neutron powder data, has shown the evidence of a tetragonal impurity phase, or a slight tetragonal distortion.

• Korean Chemical Engineering Research
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• v.49 no.1
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• pp.47-55
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• 2011

The optimum mold design and the optimum process condition were constructed upon executing process simulation of rubber injection molding with the commercial CAE program of MOLDFLOW (Ver. 5.2) in order to solve the process-problems of K company relating to cracks, which occurs at the inner cavity wall of C. V. joint boots. As a result it was confirmed that the real cracks occurs at the exactly same position of the cavity as exhibits the defects of weld and meld line and unsatisfactory curing according to the result of simulation. In order to prevent the occurrence of weld and meld line at the defect-position, the location of gate was altered to the optimum position of the cavity. Consequently the filling pattern was established to minimize the degree of the melt-fronts confronting or the melt-flows melding to prevent the occurrence of weld and meld line at the defect-position. It was observed that both gate-positions to maximize the degree of the formation of weld and meld line and air traps are located, respectively, in opposite direction each other with reference to the optimum gate position. In addition, the temperature of mold was raised by $10^{\circ}C$ and maintained at $170^{\circ}C$ for satisfactory curing.

• Journal of East Asia Management
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• v.1 no.1
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• pp.1-27
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• 2020

Military experience has a great impact on a soldier ability to handle risks. Therefore, when those soldiers become managers, they may behave differently in making risky corporate decisions, especially in activities like the R&D investment. However, studies on how military experience affect R&D have been largely missing in the largest emerging economy, i.e. China, despite that the country hires a higher percentage of military managers than the US. In addition, it remains a question whether military managers affect the state-owned enterprises (SOEs) in China, as many of the corporate decisions are made by the government. This paper tries to address these questions. The imprinting theory and the upper echelon theory suggest that managers' personal experience can affect their behaviour, which in turn influences their corporate decisions. In this paper, we examine whether managers with military experience lead to higher R&D investment and whether such an effect exists in state-owned enterprises. Based on a sample of listed firms in China's A-share market over 2008-2017, we make two findings. First, companies with military managers have high R&D investment. By dividing managers' military positions into high and low rank, we find that companies tend to have higher (lower) R&D investment if their managers hold a high-rank (low-rank) position. Second, the effect of high-rank military managers on R&D investment is more pronounced if the manager is also the founder and the company is a non-state-owned enterprise. For low-ranking military managers, a stronger effect on R&D investment is also observed if they are also the founder, but whether their companies are state-owned or not has no impact on R&D investment. This study identifies managers' military experience as a contributing factors to corporate R&D investment in the largest emerging economy. This paper tests an implication of the imprinting theory and the upper echelon theory, i.e., managers' personal experience can affect their behaviour, which in turn influences their corporate decisions. Specifically, we focus on one aspect of personal experience - military experience - and look at whether it is beneficial to firms' technological innovation, therefore enriches the literature of managerial heterogeneity. Our findings on the influence of managers' military experience on firms' technological innovation can help us better understand the role of managers play in corporate decision making, and how managers' individual traits interact with the firm's characteristics.

• Journal of KIISE:Software and Applications
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• v.26 no.10
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• pp.1204-1218
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• 1999

문서영상 검색을 위한 디지털도서관의 대부분은 논문제목과/또는 논문요약으로부터 만들어진 색인에 근거한 제한적인 검색기능을 제공하고 있다. 본 논문에서는 영문 문서영상전체에 대한 검색을 위한 단어 영상 형태 특징기반의 단어검색시스템을 제안한다. 본 논문에서는 검색의 효율성과 정확도를 높이기 위해 1) 기존의 단어검색시스템에서 사용된 특징들을 조합하여 사용하며, 2) 특징의 개수 및 위치뿐만 아니라 특징들의 순서를 포함하여 매칭하는 방법을 사용하며, 3) 특징비교에 의해 검색결과를 얻은 후에 여과목적으로 문자인식을 부분적으로 적용하는 2단계의 검색방법을 사용한다. 제안된 시스템의 동작은 다음과 같다. 문서 영상이 주어지면, 문서 영상 구조가 분석되고 단어 영역들의 조합으로 분할된다. 단어 영상의 특징들이 추출되어 저장된다. 사용자의 텍스트 질의가 주어지면 이에 대응되는 단어 영상이 만들어지며 이로부터 영상특징이 추출된다. 이 참조 특징과 저장된 특징들과 비교하여 유사한 단어를 검색하게 된다. 제안된 시스템은 IBM-PC를 이용한 웹 환경에서 구축되었으며, 영문 문서영상을 이용하여 실험이 수행되었다. 실험결과는 본 논문에서 제안하는 방법들의 유효성을 보여주고 있다. Abstract Most existing digital libraries for document image retrieval provide a limited retrieval service due to their indexing from document titles and/or the content of document abstracts. This paper proposes a word spotting system for full English document image retrieval based on word image shape features. In order to improve not only the efficiency but also the precision of a retrieval system, we develop the system by 1) using a combination of the holistic features which have been used in the existing word spotting systems, 2) performing image matching by comparing the order of features in a word in addition to the number of features and their positions, and 3) adopting 2 stage retrieval strategies by obtaining retrieval results by image feature matching and applying OCR(Optical Charater Recognition) partly to the results for filtering purpose. The proposed system operates as follows: given a document image, its structure is analyzed and is segmented into a set of word regions. Then, word shape features are extracted and stored. Given a user's query with text, features are extracted after its corresponding word image is generated. This reference model is compared with the stored features to find out similar words. The proposed system is implemented with IBM-PC in a web environment and its experiments are performed with English document images. Experimental results show the effectiveness of the proposed methods.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.2
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• pp.299-306
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• 2016

In this paper, a method of shape prediction of an endoscope handling robot that can imitate a surgeon's behavior using a sensor network is suggested. Unit sensors, which are composed of a 3-axis magnetometer and 3-axis accelerometer pair comprise the network through CAN bus communication. Each unit of the sensor is used to detect the angle of the points in the longitudinal direction of the robot, which is made from a flexible tube. The signals received from the sensor network were filtered using a low pass Butterworth filter. Here, a Butterworth filter was designed for noise removal. Finally, the Euler angles were extracted from the signals, in which the noise was filtered by the low path Butterworth filter. Using this Euler angle, the position of each sensor on the sensor network is estimated. The robot body was assumed to consist of links and joints. The position of each sensor can be assumed to be attached to the center of each link. The position of each link was determined using the Euler angle and kinematics equation. The interpolation was carried out between the positions of the sensors to be able to connect each point smoothly and obtain the final posture of the endoscope in operation. The experimental results showed that the shape of the colonoscope can be visualized using the Euler angles evaluated from the sensor network suggested and the shape of serial link estimated from the kinematics chain model.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.2
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• pp.416-426
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• 2016

This study intended to identify dental hygienists' knowledge and extent of awareness and performance of patient's personal information protection. In addition, this research was conducted to contribute to medical centers' preparation of measures to strengthen the personal information protection by identifying the factors affecting dental hygienists' extent of performance related to the patient's personal information protection. After explaining the purpose and meaning of the research to the survey participants and gaining their consent, a self-administered survey was conducted from November 7, 2014 to June 30, 2015. The data on 210 dental hygienists in Busan city and Gyeongsangnam-do province was used for analysis. As a result, in dental hygienists with more than 10 years experience, the extent of the performance was significantly high (p<.05). In positions higher than a senior manager, the extent of knowledge was high (p<.01) and the extent of performance was significantly high (p<.05). In hospitals with more than 10 to 20 workers, the extent of awareness was significantly high (p<.05). Regarding the correlation of knowledge and the extent of awareness and performance, a high level of knowledge showed a positive correlation of the extent of awareness and performance (p<.01). As a result of a survey regarding what effects dental hygienists' knowledge and extent of awareness of patient's personal information protection have on dental hygienists' extent of performance, it was found that knowledge (.231) and the extent of awareness (.212) are factors affecting the extent of performance. Therefore, to increase the extent of dental hygienists' performance of patient's personal information protection, there is a need to improve the knowledge of patient's personal information protection and change its awareness. To change the awareness of patient's personal information protection, there is a serious need to carry out education targeting dental hygienists.