• The Journal of Korean Society of Virology
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• v.26 no.2
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• pp.215-225
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• 1996

Aseptic meningits, an acute inflammation of the meninges, is a common illness during childhood. Virus is the most important cause of aseptic meningitis. Especially enterovirus causes approximately above 85% of all cases of aseptic meningitis. In 1993, there was a big epidemic of aseptic meningitis by ECHO 9 and ECHO 30 viruses. And ECHO 3 virus was isolated as a causative agent of aseptic meningitis in 1994. This study was aimed to detect the causative agent of aseptic meningitis in 1995 and to analyze the 5'-noncoding region which was used to detect virus. Virus was isolated from 87 stools and cerebrospinal fluid specimens of the patients by cultured RD and HEp-2 cell. Neutralizing antibody tests using enterovirus serum pool were performed on the specimens with cytopathic effect. 3 of ECHO 7 viruses and 5 of Coxsackie B3 viruses were isolated from stool specimens and 1 of ECHO 7 and Coxsackie B3 mixed type was confirmed from cerebrospinal fluid specimens. RNA was isolated from the culture supernatants of infected cells and general primers were selected in highly conserved part of the 5'-noncoding region of the enteroviral genome for RT-PCR. PCR product from this virus showed a 152bp band on gel electrophoresis. Sequence of obtained DNA was compared with prototype sequences by accessing to the Genebank database. 5'-noncoding region of isolated Coxsackie B3 virus, which has point mutations in nucleotide sequence positions 493, 497, 502, 523, was closely related to that of polio virus type 1, Mahoney strain. In case of isolated ECHO 7 virus, nucleotide has been changed from cytosine to thymine at position 581 and from thymine to cytosine at position 583. We concluded the causative agents of the outbreak of aseptic meningitis during June to July in 1995 were both ECHO 7 and Coxsackie B3 virus, and the primer used in this study could allow a rapid diagnosis of enteroviruses by PCR.

• Journal of Animal Science and Technology
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• v.45 no.6
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• pp.933-938
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• 2003

This study was performed to analyse the sequences of variations of mtDNA D-loop and their effects on carcass traits in Hnawoo(Korean cattle). The resulting sequences were compared with previously published sequences for other cattle breeds(GenBank J01394). The PCR was used to amplify a total of 964 bp between nucleotide 15758 and 383 within D-loop region of mtDNA using specific primers. Twenty five polymorphic sites by nucleotide substitution were found in mtDNA of Hanwoo. The frequencies of positions at 169, 16042, 16093, 16119, 16255 and 16302 nt with high levels of sequence polymorphism were 0.891, 0.117, 0.109, 0.182, 0.197 and 0.117, respectively. The substitution effect at 169 and 16119 nt was found significant on marbling score. Also substitution effect at 169 and 16042 nt was highly significant(p〈0.01) on backfat. thickness. Polymorphism of mtDNA sequence in D-loop region could be useful for the analysis of cytoplasmic genetic variation and associations with the other economically important traits and maternal lineage analysis in Hanwoo.

• Bulletin of the Korean Chemical Society
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• v.33 no.5
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• pp.1581-1585
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• 2012

Two pyridinecarboxamide dicyanidecobalt(III) building blocks and two mononuclear seven-coordinated macrocycle manganese(II) compounds have been rationally selected to assemble cyanide-bridged heterobimetallic complexes, resulting in three cyanide-bridged $Co^{III}-Mn^{II}$ complexes. Single X-ray diffraction analysis show that these complexes $\{[Mn(L^1)][Co(bpb)]\}ClO_4{\cdot}CH_3OH{\cdot}0.5H_2O$ ($\mathbf{1}$), $\{[Mn(L^2)][Co(bpb)]\}ClO_4{\cdot}0.5CH_3OH$ ($\mathbf{2}$) and ${[Mn(L^1)][Co(bpb)]\}ClO_4{\cdot}H_2O$ ($\mathbf{3}$) ($L^1$ = 3,6-diazaoctane-1,8-diamine, $L^2$ = 3,6-dioxaoctano-1,8-diamine; $bpb2^{2-}$ = 1,2-bis(pyridine-2-carboxamido)benzenate, $bpmb2^{2-}$ = 1,2-bis(pyridine-2-carboxamido)-4-methyl-benzenate) all present predictable one-dimensional single chain structures. The molecular structures of these one-dimensional complexes consists of alternating units of $[Mn(L)]^{2+}$ ($L=L^1$ or $L^2$) and $[Co(L^{\prime})(CN)2]^-$ ($L^{\prime}=bpb2^{2-}$, or $bpmb2^{2-}$), forming a cyanide-bridged cationic polymeric chain with free $ClO_4{^-}$ as the balance anion. The coordination geometry of manganese(II) ion in the three one-dimensional complexes is a slightly distorted pentagonal-bipyrimidal with two cyanide nitrogen atoms at the trans positions and $N_5$ or $N_3O_2$ coordinating mode at the equatorial plane from ligand $L^1$ or $L^2$. Investigation over magnetic properties of these complexes reveals that the very weak magnetic coupling between neighboring Mn(II) ions connected by the diamagnetic dicyanidecobalt(III) building block. A best-fit to the magnetic susceptibility of complex ${\mathbf}{1}$ leads to the magnetic coupling constants $J=-0.084(3)cm^{-1}$.

• Geophysics and Geophysical Exploration
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• v.15 no.2
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• pp.66-74
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• 2012

This paper presents development of a three-dimensional marine controlled-source electromagnetic (mCSEM) modeling algorithm and its application to a salt and reservoir model to examine detectability of mCSEM for a reservoir under complex subsurface structures. The algorithm is based on the finite difference method, and employs the secondary field formulation for an accurate and fast calculation of modeling responses. The algorithm is verified for a two-layer model by comparing solutions not only with analytic solutions but also with those from other 3D modeling algorithm. We calculate and analyze electric and magnetic fields and their normalized responses for a salt and reservoir model due to three sources located at boundaries between a salt, a reservoir, and background. Numbers and positions of resistive anomalies are informed by normalized responses for three sources, and types of resistive anomalies can be informed when there is a priori information about a salt by seismic exploration.

• Korean Journal of Cognitive Science
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• v.23 no.2
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• pp.133-164
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• 2012

Paul Churchland(1989) suggests the theory of representation from the results of cognitive biology and connectionist AI studies. According to the theory, our representations of the diverse phenomena in the world can be represented as the positions of phase state spaces with the actions of the neurons or of the assembly of neurons. He insists connectionist AI neural networks can have the semantical category systems to recognize the world. But Fodor and Lepore(1996) don't look the perspective bright. From their points of view, the Churchland's theory of representation stands on the base of Quine's holism, and the network semantics cannot explain how the criteria of semantical content similarity could be possible, and so cannot the theory. This thesis aims to excavate which one is the better between the perspective of the theory and the one of Fodor and Lepore's. From my understandings of state space theory of representation, artificial nets can coordinates the criteria of contents similarity by the learning algorithm. On the basis of these, I can see that Fodor and Lepore's points cannot penetrate the Churchlands' theory. From the view point of the theory, we can see how the future's artificial systems can have the conceptual systems recognizing the world. Therefore we can have the perspectives what cognitive scientists have to focus on.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.26 no.2
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• pp.165-171
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• 2013

Due to the difficulty in considering dynamic load in the view point of a computer resource and computing time, it is common that external load is assumed as ideal static loads. However, structural analysis under static load cannot guarantee the safety of design of the structures under dynamic loadings. Recently, the systematic method to construct equivalent static load from the given dynamic load has been proposed. Previous study has calculated equivalent static load through the optimization procedure under displacement constraints. However, previously reported works to distribute equivalent static load were based on ad-hoc methods. Improper selection of equivalent static loading positions may results in unreliable prediction of structural design. The present study proposes the selection method of the proper locations of equivalent static loads to dynamically applied loads when we consider transient dynamic structural problems. Moreover, it is appropriate to take into account the stress constraint as well as displacement constraint condition for the safety design. But the previously reported studies of equivalent static load design methods considered only displacement constraint conditions but not stress constraint conditions. In the present study we consider not only displacement constraint but also stress constraint conditions. Through a few numerical examples, the efficiency and reliability of proposed scheme is verified by comparison of the equivalent stress between equivalent static loading and dynamic loading.

• Geomechanics and Engineering
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• v.10 no.4
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• pp.471-526
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• 2016

In order to investigate water flow characteristics after inrushing in process of karst tunnel excavation, numerical simulations for five case studies of water inrush from the tunnel floor are carried out by using the FLUENT software on the background of Qiyueshan high risk karst tunnel. Firstly, the velocity-distance curves and pressure-distance curves are drawn by selecting a series of probing lines in a plane. Then, the variation characteristics of velocity and pressure are analyzed and the respective optimized escape routes are made. Finally, water flow characteristics after inrushing from the tunnel floor are discussed and summarized by comparing case studies under the conditions of different water-inrush positions and excavation situations. The results show that: (1) Tunnel constructors should first move to the tunnel side wall and then escape quickly when water inrush happens. (2) Tunnel constructors must not stay at the intersection area of the cross passage and tunnels when escaping. (3) When water inrush from floor happens in the left tunnel, if tunnel constructors meet the cross passage during escaping, they should pass through it rapidly, turn to the right tunnel and run to the entrance. (4) When water inrush from floor happens in the left tunnel, if there is not enough time to escape, tunnel constructors can run to the trolley and other equipment in the vicinity of the right tunnel working face. In addition, some rescuing equipment can be set up at the high location of the cross passage. (5) When water inrush from floor happens in the cross passage, tunnel constructors should move to the tunnel side wall quickly, turn to the tunnel without water inrush and run to the entrance. (6) When water inrush from floor happens in the cross passage, if there is not enough time to escape, tunnel constructors can run to the trolley and other equipment near by the left or the right tunnel working face. The results are of important practical significance and engineering value to ensure the safety of tunnel construction.

• Archives of Craniofacial Surgery
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• v.17 no.1
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• pp.9-13
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• 2016

Background: Position of the facial foramina is important for regional block and for various maxillofacial surgical procedures. In this study, we report on anthropometry and morphology of these foramina using three-dimensional computed tomography (3D-CT) data. Methods: A retrospective review was performed for all patients who have undergone 3D-CT scan of the facial skeleton for reasons other than fracture or deformity of the facial skeleton. Anthropometry of the supraorbital, infraorbital, and mental foramina (SOF, IOF, MF) were described in relation to facial midline, inferior orbital margin, and inferior mandibular margin (FM, IOM, IMM). This data was analyzed according to sex and age. Additionally, infraorbital and mental foramen were classified into 5 positions based on the anatomic relationships to the nearest perpendicular dentition. Results: The review identified 137 patients meeting study criteria. Supraorbital foramina was more often in the shape of a foramen (62%) than that of a notch (38%). The supraorbital, infraorbital, and mental foramina were located 33.7 mm, 37.1 mm, and 33.7 mm away from the midline. The mean vertical distance between IOF and IOM was 13.4 mm. The mean distance between MF and IMM was 21.0 mm. The IOF and MF most commonly coincided with upper and lower second premolar dentition, respectively. Between the sex, the distance between MF and IMM was significantly higher for males than for female. In a correlation analysis, SOF-FM, IOF-FM and MF-FM values were significantly increased with age, but IOF-IOM values were significantly decreased with age. Conclusion: In the current study, we have reported anthropometric data concerning facial foramina in the Korean population, using a large-scale data analysis of three-dimensional computed tomography of facial skeletons. The correlations made respect to patient sex and age will provide help to operating surgeons when considering nerve blocks and periosteal dissections around the facial foramina.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.9 no.4
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• pp.55-64
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• 2014

While small and medium-sized companies are suffering from a shortage of workers as a result of social tendency to avoid those companies, college graduates still prefer large companies or governmental positions, which consequently results in inconsistencies in the demand and supply of work forces. The gap between them is getting so bad that employment difficulties are exacerbating. Accordingly this study tries to search for potential employee's expected value factors which make people select small and medium companies not big companies. A survey was conducted from October 1 to october 30, 2012 with university students in the Seoul metropolitan area. a total of 350 questionnaires were distributed and 335 were collected. of these, 332 questionnaires were used for data analyses excluding questionnaires with missing values. Data was analyzed by frequency, descriptive factor, reliability, and regression with SPSS win 18.0 program The result of this study were as follows. A factor analysis extracted four factors comprising small and medium companies, which we named career(factor 1), working environment(factor 2), working achievement(factor 3), job security (factor 4). This study showed that small and medium companies' preference were affected by the career, working environment, job security, corporate reputation, salary.

• Journal of Navigation and Port Research
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• v.38 no.4
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• pp.373-378
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• 2014

In order to prepare for recapitalization of differential GNSS (DGNSS) reference station and integrity monitor (RSIM) due to GNSS diversification, this paper focuses on differential correction algorithm using GPS/Galileo pesudorange. The technical standards on operation and broadcast of DGNSS RSIM are described as operation of differential GPS (DGPS) RSIM for conversion of DGNSS RSIM. Usually, in order to get the differential corrections of GNSS pesudorange, the system must know the real positions of satellites and user. Therefore, for calculating the position of Galileo satellites correctly, using the equation for calculating the SV position in Galileo ICD (Interface Control Document), it estimates the SV position based on Ephemeris data obtained from user receiver, and calculates the clock offset of satellite and user receiver, system time offset between GPS and Galileo, then determines the pseudorange corrections of GPS/Galileo. Based on a platform for performance verification connected with GPS/Galileo integrated signal simulator, it compared the PRC (pseudorange correction) errors of GPS and Galileo, analyzed the position errors of DGPS, DGalileo, and DGPS/DGalileo respectively. The proposed method was evaluated according to PRC errors and position accuracy at the simulation platform. When using the DGPS/DGalileo corrections, this paper could confirm that the results met the performance requirements of the RTCM.