• 대한환경공학회지
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• 제22권7호
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• pp.1319-1330
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• 2000

유기성폐슬러지를 염화아연과 황화칼륨으로 약품활성화하여 제조한 활성탄의 세공발달과 흡착특성을 연구하였다. 유기성폐슬러지로 제조한 탄소의 세공발달은 77K에서 질소흡착법을 이용하여 특성화하였다. 염화아연으로 약품활성화하여 제조한 $ZnCl_2$-활성탄은 활성화공정에 의해 미세공이 형성되었음을 지적해주는 BDDT 분류의 type I의 흡착특성을 보여주었다. 상용 분말활성탄과 $K_2S$-활성탄은 BDDT 분류의 type IV와 유사한 이력현상을 나타냈는데, 이것은 이들 활성탄에 중세공이 형성되었음을 말해준다. 이것은 $K_2S$-활성탄은 주로 중세공과 미세공으로 이루어졌으며, 거대세공의 발달은 미비하다는 것을 의미한다. 유기성폐슬러지로 제조한 $K_2S$-활성탄의 중금속 흡착능은 상용입상활성탄보다 우수한 것으로 나타났다. $K_2S$-활성탄에 대한 중금속의 흡착은 단분자층 흡착을 나타내는 Langmuir와 Freundlich 등온식에 잘 부합되었다. $PO_4$-P에 대한 흡착능은 $K_2S$-활성탄이 $ZnCl_2$-활성탄보다 우수한 것으로 나타난 반면, $NO_3$-N의 흡착은 $ZnCl_2$-활성탄이 우수한 것으로 나타났다. 본 연구결과, 활성화제로 염화아연과 황화칼륨을 사용하여 유기성폐슬러지를 약품처리할 경우, 탄화와 활성화공정을 거치는 2단계 공정을 통하여 상용입상활성탄보다 흡착능이 뛰어난 활성탄을 제조할 수 있었다.

• 공업화학
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• 제10권7호
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• pp.1066-1072
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• 1999

고기능성 건설재료로 활용하기 위하여 불포화폴리에스테르수지를 사용한 폴리머 콘크리트의 물성에 대하여 조사하였다. 탄산칼슘(충전제)의 첨가량(5~20 wt %)과 세골재의 첨가량(10~50 wt %)에 따라 다양한 배합의 공시체를 제작하여 압축 및 휨강도, 흡수시험, 내열수성시험, 내산성시험, 세공분포측정 및 SEM에 의한 미세조직 관찰등을 실시하였다. 그 결과 폴리머 콘크리트의 압축강도와 휨강도는 시멘트 콘크리트보다 4배 정도 향상되었고, 흡수율은 1/100로 감소되었으며, 내산성시험에 의한 중량감소율은 1/27로 현저히 감소되었다. 내열수성시험후에 측정한 폴리머 콘크리트의 압축 및 휨강도는 모두 내열수성시험전에 측정한 강도에 비하여 67%, 47%로 각각 감소되었으며 폴리머결합재의 분해에 의하여 세공량과 세공율은 크게 증가되었다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2006년도 춘계학술대회 논문집
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• pp.159-160
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• 2006

A novel approach to the manufacture of biocompatible ceramic scaffold for tissue engineering using micro-stereolithography system is introduced. Micro-stereolithography is a newly proposed technology that enables to make a 3D micro structure. The 3D micro structures made by this technology can have accurate and complex shape within a few micron error. Therefore, the application based on this technology can vary greatly in nano-bio fields. Recently, tissue-engineering techniques have been regarded as alternative candidate to treat patients with serious bone defects. So many techniques to design and fabricate 3D scaffolds have been developed. But the imperfection of scaffold such as random pore size and porosity causes a limitation in developing optimum scaffold. So scaffold development with controllable pore size and fully interconnected shape have been needed for a more progress in tissue engineering. In this paper, bone scaffold was developed by applying the micro-stereolithography to the mold technology. The scaffold material used was HA(Hydroxyapatite) nano powder. HA is a type of calcium phosphate ceramic with similar characteristic to human inorganic bone component. The bone scaffold made by HA is expected, in the near future, to be an efficient therapy for bone defect.

• ALGAE
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• 제33권4호
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• pp.305-318
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• 2018

In Trachelomonas hispida, the adult envelope that surrounds the monad is oval in shape and covered with spines. Development of the lorica is an interesting, but poorly known phenomenon. We observed in detail the formation of spineless envelopes of T. hispida using light microscopy and scanning electron microscopy. The results showed that young cells formed delicate and net-like envelopes. The structure changed with age, and mature specimens had solid, thick loricae with small pores. As the loricae aged, they changed their shape, and rope-like fibres from the external layer started to unwind, progressing from the apical pore, exposing the underlying net-like structure. X-ray spectrometry showed that Fe was the major mineral component in young and mature loricae, whereas old loricae did not contain Fe salts, although they did contain a high number of Mn compounds. We also noticed a different pattern of mineralization process in the envelopes. Apart from the even distribution of mineral deposition over the entire lorica, we observed that it started from the apical pore and ended at the posterior end. There was considerable morphological variation in envelope shape and ornamentation, which had collars and folds around the apical pore and process at the posterior end. This suggested that many varieties of T. hispida should be taxonomically reappraised. We also discuss a hypothetical role for the spines on lorica surfaces in aquatic ecosystems.

• FOCUS: LIFE SCIENCE
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• 제1호
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• pp.3.1-3.7
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• 2024

The article discusses the critical role of chromatography in the analysis and purification of proteins in biopharmaceuticals, emphasizing the importance of comprehensive characterization for ensuring their safety and efficacy. It highlights the use of Avantor® ACE® HPLC columns for the separation and purification of proteins, focusing on the analysis of intact proteins using reversed-phase liquid chromatography (RPLC) with fully porous particles. This article also details the application of different mobile phase additives, such as TFA and formic acid, and emphasizes the advantages of using type B ultra-pure silica-based columns for efficiency and peak shape in biomolecule analysis. Additionally, it addresses the challenges of analyzing intact proteins due to slow molecular diffusion and introduces the concept of solid-core (or superficially porous) particles, emphasizing their benefits over traditional porous particles for the analysis of therapeutic proteins. Furthermore, it discusses the development of Avantor® ACE® UltraCore BIO columns, specifically designed for the high-efficiency separation of large biomolecules, such as proteins, and demonstrates their effectiveness in achieving high-resolution separations, even for higher molecular weight proteins like monoclonal antibodies (mAbs). In addition, it underscores the complexity of analyzing and characterizing intact protein biopharmaceuticals, requiring a range of analytical techniques and the use of wide-pore stationary phases, operated at elevated temperatures and with relatively shallow gradients. It highlights the comprehensive range of options offered by Avantor® ACE® wide pore columns, including both fully porous and solid-core particles, bonded with a variety of complementary stationary phase chemistries to optimize selectivity during method development. The use of ultrapure and highly inert base silica is emphasized for enabling the use of lower concentrations of mobile phase modifiers without compromising analyte peak shape, particularly beneficial for LC-MS applications. Then the article concludes by emphasizing the significance of reversed-phase liquid chromatography and its compatibility with mass spectrometry as a valuable tool for the separation and analysis of intact proteins and their closely related variants in biopharmaceuticals.

• 대한화학회지
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• 제52권6호
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• pp.622-629
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• 2008

• 콘크리트학회논문집
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• 제16권6호
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• pp.875-881
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• 2004

The quality of recycled aggregate is affected by original concrete strength and the manufacturing process of recycled aggregates. In this study, the porosity of old and new mortar, and the compressive strength of concrete were investigated to examine the influence of recycled aggregate on the concrete. Six kinds of recycled coarse aggregates were produced from concrete blocks of differing strength levels (A:60. 1MPa, B:41.7MPa, C:25.5MPa). Original concrete strength and the bond mortar of recycled aggregate influences the pore structures of both old and new mortar. The pore size distribution of old mortar was found to be greatly affected by age, and the reduction of the porosity of bond mortar on low strength recycled aggregate increased at a greater rate than that of bond mortar on high strength recycled aggregate. The pore size distribution of new mortar in recycled aggregate concrete changed in comparison with that of new mortar in virgin aggregate concrete. The total porosity of new mortar using B level recycled aggregates was smaller than that of new mortar with A, and C level recycled aggregates. Moreover, the compressive strength of recycled aggregate concrete was found to have been affected by original concrete strength. The compressive strength of concrete only changed slightly in the porosity of new mortar over $15\%$, but increased rapidly in the porosity of new mortar fewer than $15\%$.

• Journal of Pharmaceutical Investigation
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• 제27권1호
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• pp.39-49
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• 1997

Nicotinic acid was mixed with glass powders such as controlled pore glass (CPG), glyceryl controlled pore glass (GPG) and glass beads (GB) at room temperature. The physicochemical properties of nicotinic acid in the various mixtures were examined by differential thermal analysis, X-ray diffraction study. Infrared spectroscopy and BET gas adsorption measurements. The peak area at the melting point from the various mixtures of nicotinic acid and CPG was increased with an increase of nicotinic acid concentration while the broad peak area was remained unchanged in the DTA curve. As shown in the powder X-ray diffraction patterns, the crystalline peaks of nicotinic acid disappeared in mixture with CPG, suggesting the interaction of nicotinic acid and porous powders. It was found that the larger the content of CPG, the higher the ratio of an amorphous state to a crystalline state. BET isotherm showed that as the amount of nicotinic acid was increased, the specific surface area was reduced proportionally to nicotinic acid content of up to 40% and remained constant thereafter. Sublimation of nicotinic acid from the mixture of nicotinic acid and CPG was examined. A large quantity of nicotinic acid was retained in the mixture when stored on various temperatures in vacuo for 10 hours. The nicotinic acid mixtures with CPG or GPG showed a high dissolution rates of nicotinic acid in aqueous solution, especially in the initial dissolution stage. CPG is expected to be a good pharmaceutical excipient to reduce the crystallinity of drugs and to prevent sublimation of drugs.

• 에너지공학
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• 제7권1호
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• pp.57-64
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• 1998

폴리에스터와 스테인레스스틸섬유를 재료로 제조된 제전사여과포에 대한 물리화학적 특성시험 및 여과포성능 기초시험을 수행하였다. 실험용먼지로 제철.제강, 시멘트제조, 열공급시설 및 폐기물공정에서 채취된 먼지를 처리하여 사용하였다. 제전사여과포의 물리화학적 특성 실험에서는 산성분위기하에서 인장강도 및 초기탄성계수변화를 조사하였고, Automated Permporometer를 이용하여 평균흐름세공압력, 기포점 세공지름, 평균흐름세공지름 및 세공크기분포를 구하였다. 또한 벤처규모의 여과포 기초성능 시험장치를 이용하여 먼지부하에 따른 압력손실, 먼지통과율 및 여과포성능 평가지표를 산출하였다. 산성가스 및 분위기하에서 제전사여과포의 인장강도는 온도 및 노출시간과 깊은 관련이 있었다. 압력손실은 여과속도와 먼지부하가 증가함에 따라 증가하였으며 증가형태는 먼지의 종류에 따라 달랐다. 먼지 통과율은 먼지종류에 관계없이 먼지부하의 증가에 따라 급격히 감소하는 경향을 나타내었다. 여과포성능지표는 먼지 포집 초기에는 증가했다가 급격히 감소하여 일정하게 유지되었다.

• 에너지공학
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• 제7권1호
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• pp.103-112
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• 1998

산업용 직물여과포의 운전에서 발견되는 다양한 문제점들을 해결하기 위한 일환으로 내열성여과포를 개발하여 성능을 규명하였다. 국내 산업체에서 배출되는 대표적인 네 종류의 먼지들, 즉 제철공정의 코크먼지, 시멘트 제조업체의 시멘트 먼지, 유동층 연소로의 비산회재, 그리고 폐플라스틱 소각로의 연소재에 대하여 여과포의 성능을 시험하였다. 내열성여과포의 물리화학적 특성은 평균 세공흐름압력 및 기포점 세공지름, 평균흐름 세공지름, 세공크기분포, SO2 및 NO2 분위기에서의 물성변화의 항목으로 평가 되었다. 또한, 벤치규모의 필터시험장치에서 직물여과포에 대한 압력손실, 먼지 통과율, 여과포 성능 평가지수를 조사하였다. 본 연구에서 개발된 직물여과포는 양호한 물리화학적 필터 특성을 지니고 있으며 전형적인 산업체 먼지를 처리하는데 적합하였다.