• Asian Pacific Journal of Cancer Prevention
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• v.13 no.2
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• pp.665-669
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• 2012

Aim: The distribution of DNA repair gene XRCC1 and XRCC3 genotypes was used to assess the potential influence of genetic polymorphisms on risk of colorectal cancer, and interactions with other factors. Methods: a 1:2 matched case-control study was conducted with 485 cases and 970 controls. XRCC1 and XRCC2 genotype polymorphisms were based upon duplex polymerase-chain-reaction with the confronting-two-pairprimer (PCR-CTPP) method. Results:The XRCC1 399Cln allele polymorphism was found to be associated with an increased colorectal cancer risk, while an non-significant inversely association was noted for XRCC3 241Thr/Thr genotype. We also found that individuals with the XRCC1 399 Gln and XRCC3 241Met alleles had an elevated risk, while XRCC3241Thr/Thr was proctective. Conclusion: This study is the first to provide evidence of importance of XRCC1 and XRCC3 gene polymorphisms for risk of colorectal cancer in the Chinese population.

• The Korean Journal of Health Service Management
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• v.11 no.3
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• pp.65-78
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• 2017

Objectives : Obesity is a worldwide health concern due to an increasing obese population. This study proposed to analyze the differences in medical costs and care utilization between obese and normal group using propensity score matching. Methods : Data were collected from the sample cohort database by the Korea National Health Insurance Corporation. Propensity score matching(PSM) was applied to control selection bias, and factors affecting obesity were used as covariates in PSM. Results : The results showed higher medical costs and care utilization in the obese group than the normal group. According to gender and medical type, there were differences in the relationships between obesity and medical charges and utilization. In particular, the differences in the female population were larger in both outpatients and inpatients than the male population. Conclusions : It is important to manage obesity, because obesity has a negative effect on national health insurance costs. These findings suggest directions for future research.

• Journal of Ecology and Environment
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• v.30 no.4
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• pp.319-324
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• 2007

To investigate the impacts of transgenic rice on freshwater organisms, we conducted two life table experiments using Daphnia magna for fifteen and twenty days, respectively. We examined life history traits such as population growth rates (r), reproductive rates ($R_0$), generation times, and survivorship. In the first experiment, we used non-drought-stressed transgenic and non-transgenic rice harvested in 2005. In the second study, we used non-transgenic and transgenic rice harvested in 2006 following drought stress. Each experiment involved three treatments in which D. magna neonates were fed with Selenastrum capricornutum (control treatment) and S. capricornutum with 5% aqueous extracts of non-transgenic rice (N-T) and transgenic rice (T). In the first experiment, D. magna showed reduced population growth rates and lowered fecundity in the N-T and T treatments. In the second experiment, D. magna receiving both transgenic and non-transgenic rice extracts showed very high mortality, low population growth rates and reproduction rates. We could not detect any significant negative effects of extracts from transgenic rice on D. magna life history traits at 95%.

• Korean Journal of Health Education and Promotion
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• v.4 no.2
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• pp.95-135
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• 1987

According to U.S. Bureau of Census (1984), the number of older adults (over the age of sixty) has grown twice as fast as the rest of the population over the past twenty-five years. It is predicted that between 1980 and 2020, their number will double again, In 1985, National Bureau of Statistics, Economic Planning Board, Republic of Korea reported that the number of older adults over 60 years of age was 2.7 million (6.7% of the total population). It is projected that their number will become 3.9 million (8% of the total population) by the year 2000.

• Research in Community and Public Health Nursing
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• v.27 no.3
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• pp.262-271
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• 2016

Purpose: Using food labels has been related to healthy eating habits and positive health outcomes. The purpose of this study is to describe the prevalence of food labels utilization and the association between food label use and obesity related factors. Methods: We conducted a self-reported population-based survey including health behaviors, 24-hour recalls, measurements of body mass indices with 6,266 Koreans aged 10 or older. ${\chi}^2$-test and ANOVA examined differences in demographic factors, health behavioral factors, and nutrition factors in tandem with food label use categories. Multivariates logistic regression was used to estimate association between food label use and obesity factors. Results: The percentages of food label users and non-users who perceive food labels were 21.8% and 48.5% respectively. In the multivariate logistic regression, food label use had significant positive associations with women, age, income, education attainment, and subjective obesity. After adjusting for socioeconomic factors and dietetic treatments, the positive associations between food label use and subjective obesity, weight control, and subjective obesity with objective normal weight remained. Conclusion: In order to improve eating habits and weight management, the obesity population that does not use food labels needs to receive proper nutrition education including food choice and body image correction.

• Parasites, Hosts and Diseases
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• v.56 no.2
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• pp.175-181
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• 2018

The giant roundworm Ascaris infects pigs and people worldwide and causes serious diseases. The taxonomic relationship between Ascaris suum and Ascaris lumbricoides is still unclear. The purpose of the present study was to investigate the genetic diversity and population genetic structure of 258 Ascaris specimens from humans and pigs from 6 sympatric regions in Ascaris-endemic regions of China using existing simple sequence repeat data. The microsatellite markers showed a high level of allelic richness and genetic diversity in the samples. Each of the populations demonstrated excess homozygosity (Ho0). According to a genetic differentiation index (Fst=0.0593), there was a high-level of gene flow in the Ascaris populations. A hierarchical analysis on molecular variance revealed remarkably high levels of variation within the populations. Moreover, a population structure analysis indicated that Ascaris populations fell into 3 main genetic clusters, interpreted as A. suum, A. lumbricoides, and a hybrid of the species. We speculated that humans can be infected with A. lumbricoides, A. suum, and the hybrid, but pigs were mainly infected with A. suum. This study provided new information on the genetic diversity and population structure of Ascaris from human and pigs in China, which can be used for designing Ascaris control strategies. It can also be beneficial to understand the introgression of host affiliation.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.22
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• pp.9871-9873
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• 2014

Brain tumors are a mixed group of neoplasms that originate from the intracranial tissues and the meninges with degrees of malignancy varying greatly from benign to aggressive. Not much is known about the epidemiology of primary malignant brain tumors (PMBTs) in our population in North-East India. In this analysis, an attempt was made to identify the age groups, gender distribution, topography and different histological types of PMBT with data from a hospital cancer registry. A total of 231 cases of PMBT were identified and included for the present analysis. Our analysis has shown that most of PMBT occur at 20-60 years of age, with a male to female ratio of 2.3:1. Some 70.5% of cases occurred in cerebral lobes except for the occipital lobe, and astrocytic tumors were the most common broad histological type. In our population the prevalence of PMBT is 1% of all cancers, mostly affecting young and middle aged patients. As brain tumors are rare, so case-control analytic epidemiological studies will be required to establish the risk factors prevalent in our population.

• Korean Journal of Health Education and Promotion
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• v.33 no.4
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• pp.1-9
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• 2016

Objectives: This review is to suggest strategies to reduce risk factors of non-communicable diseases (NCD) in South Korea. Methods: Prior research findings on the burden of NCD and associated risk factors and the effectiveness of intervention programs were reviewed. Strategies regarding the control of NCD risk factors were conceived. Results: The author presented research findings from the Global Burden of Disease study on the burden of non-communicable disease (NCD) and associated risk factors in South Korea. Strengths and limitations of population and high-risk strategies for preventing NCDs were introduced. The author also reviewed the evidence on the effectiveness of multiple cardiovascular risk factor interventions and community-based intervention programs on cardiovascular diseases conducted in industrialized countries. Finally, strategies to reduce NCD risk factors in South Korea were suggested. Conclusions: The evidence-based interventions and the importance of population strategies in NCD prevention were highlighted. The author indicated that strategies employed by unhealthy commodity industries to undermine effective public health policies and programs should be actively monitored. It has been suggested that effective high-risk strategies with ecological models to address social risks rather than medical risks among disadvantaged population should be further developed in South Korea.

• Journal of Environmental Science International
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• v.25 no.3
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• pp.447-456
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• 2016

Access to clean and affordable water is one of the fundamental human rights because water is essential to life and a foundation for socioeconomic development of any country in the world. Despite the efforts to secure water supply in Burundi, the amount of water supplied by public utilities does not meet the demand of the population because population keeps increasing with fluctuation of weather conditions. This study selected north Bujumbura that is a sprawling new residential area in the western part of Burundi as a case to investigate the potential of rainwater harvesting in meeting water demand of the country. Based on a long-term average monthly precipitation in the region, the rainwater harvesting potential was assessed as a function of roof sizes, number of households, and runoff coefficients of roof materials. For the entire region of north Bujumbura, the current water supply capacity of the local water company combined with the rainwater harvesting potential resulted in the water surplus of $468,604.1m^3/yr$. Although three communes among them still showed water deficit in dry season, they still got help from rainwater to relieve their water shortage. This suggests that at the regional scale, proper storages and water quality control for harvestable rainwater could contribute to relieving the regional water shortage and allow the population growth.

• Korean Journal of Occupational Health Nursing
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• v.29 no.4
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• pp.247-253
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• 2020

Purpose: Multimorbidity is defined as the coexistence of multiple chronic diseases within a person. This study explores the burden of multimorbidity in the working population, focusing on the recent increase in elderly workers in Korea. Methods: We summarized past empirical or theoretical literature. Results: Previous literature shows that about 80% of the elderly are multimorbid, and more than half of people with chronic disease have two or more chronic conditions. Multimorbidity is a common phenomenon in the elderly working population. However, little is known about its prevalence, the factors related to its unequal distribution among workers, and its effects on health outcome measures such as mortality, medical use, and employment decisions. Conclusion: This study asks researchers to focus on a subgroup analysis employing data on the working population. Health professionals need to develop clinical guidelines for multimorbid patients. As multimorbidity is a major health concern in the working elderly, prevention and control should be promoted in the workplace.