• Journal of IKEEE
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• v.26 no.3
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• pp.416-421
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• 2022

In this study, we present a fully automated system that combines camera technology with liquid crystal technology to create a polarization camera capable of detecting the partial linear polarization of light reflected from an object. The use of twisted nematic (TN) liquid crystals that electro-optically modulate the polarization plane of light eliminates the need to mechanically rotate the polarizing filter in front of the camera lens. Images obtained using these techniques are imaged by computer software. In addition, liquid crystal panels have been produced in a square shape, but many camera lenses are usually round, and lighting or other driving units are installed around the lens, so space is optimized through the application of a circular liquid crystal display. Through the development of this technology, an electrically switchable and space-optimized liquid crystal polarizer is developed.

• Proceedings of the Korea Association of Crystal Growth Conference
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• 1999.06a
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• pp.419-431
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• 1999

InP, III-V binary compound semiconductor, single crystal was grown by VGF (vertical gradient freeze) method using quartz ampoule and its electrical optical properties were investigated. Phosphorous powders were put in the bottom of quartz ampoule and Indium metal changed in conical quartz crucible hat was attached at the upper side position inside the quartz ampoule. It was vacuous under the pressure of 10-5 Torr and sealed up. In metal in the quartz crucible was melted at 1070$^{\circ}C$ and phophorous sublimated at 450$^{\circ}C$, there after it was diffused in In melt and so InP composition was formed. By cooling the InP composition melt (2$^{\circ}C$∼5$^{\circ}C$/hr of cooling rate) in range of 1070$^{\circ}C$∼900$^{\circ}C$, InP crystal was grown. the grown InP single crystals were investigated by X-ray analysis and polarized optical microscopy. Electrical properties of them were measured by Van der Pauw method. At the cooling rate of 2$^{\circ}C$/hr, its direction was (111), quality of the ingot ws better upper side of the ingot than lower. It was found that the InP crystals were n-type semiconductor and the carrier concentration, electron mobility and relative resistivity were 1015∼1016/㎤, 2x103∼3x104$\textrm{cm}^2$/Vsec and 2x10-1∼2x10-3Ωcm in the range of 150K∼300K, respectively.

• Archives of Plastic Surgery
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• v.50 no.4
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• pp.432-442
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• 2023

Background Macrophages play a major role in wound healing and prevent infection from the outside. Polarization conversion of macrophages regulates aspects of inflammation, and two macrophages, M1 (classically activated) and M2 (alternatively activated), exist at both ends of broad-spectrum macrophage polarization. Thus, we aimed to investigate whether macrophage polarization can be artificially regulated. To this end, MgSO4 and small-interfering RNA (siRNA) targeting magnesium transport 1 (MAGT1) were used to investigate the effects of intracellular magnesium (Mg2+) concentrations on the differentiation of macrophages in vitro. Methods THP-1 derived macrophages maintained in a culture medium containing 5 mM MgSO4 and siRNA to inhibit the expression of MAGT1. As comparative groups, THP-1 derived macrophages polarized into M1 and M2 macrophages by treatment with M1, M2 inducer cytokine. The polarization status of each group of cells was confirmed by cell surface antigen expression and cytokine secretion. Results We found that MgSO4 treatment increased CD163 and CD206, similar to the effect noted in the M2 group. The expression of CD80 and HLA-DR was increased in the group treated with MAGT1 siRNA, similar to the effect noted in the M1 group. Functional assays demonstrated that the group treated with MgSO4 secreted higher levels of IL-10, whereas the MAGT1 siRNA-treated group secreted higher levels of IL-6 cytokines. Additionally, the conditional medium of the Mg2+ treated group showed enhanced migration of keratinocytes and fibroblasts. Conclusion Mg2+ can help to end the delay in wound healing caused by persistent inflammation in the early stages.

• The Korean Journal of Physiology and Pharmacology
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• v.27 no.5
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• pp.437-448
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• 2023

Diabetic ulcer is usually seen in people with uncontrolled blood sugar. Reportedly, many factors such as impaired glucose metabolism, and macrovascular and microvascular diseases caused angiogenesis disorders and delayed the healing of diabetic ulcers, thus affecting the body's metabolism, nutrition, and immune function. This study aimed to explore the effect of paeonol on skin wound healing in diabetic rats and the related mechanism. A rat model of diabetic ulcer was established. High glucose-treated mouse skin fibroblasts were co-cultured with M1 or M2-polarized macrophages treated with or without paeonol. H&E and Masson staining were used to reveal inflammatory cell infiltration and collagen deposition, respectively. Immunohistochemistry visualized the expression of Ki67, CD31, and vascular endothelial growth factor (VEGF). Western blot was used to detect interleukin (IL)-1β, tumor necrosis factor (TNF)-α, IL-4, IL-10, CD31, VEGFA, and collagen I/III. The expression of iNOS and arginase 1 was revealed by immunofluorescence staining. Paeonol treatment augmented collagen deposition and the expression of Ki67, CD31, VEGF, and macrophage M2 polarization markers (IL-4 and IL-10) and reduced wound area, inflammatory cell infiltration, and macrophage M1 polarization markers (IL-1β and TNF-α) in the ulcerated area. In vitro, paeonol treatment promoted M2-polarization and repressed M1-polarization in macrophages, thereby improving the repair of cell damage induced by high glucose. Paeonol accelerates the healing of diabetic ulcers by promoting M2 macrophage polarization and inhibiting M1 macrophage polarization.

• Clean Technology
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• v.16 no.2
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• pp.145-152
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• 2010

Various technical methods are applied for removing water from the water-retaining media, and the energy efficiency is the main concern in those methods. The electroosmotic process is studied as an efficient way for dewatering. An experimental electroosmotic reactor is designed and used for evaluating the effects of operational variables. The operational variables such as the electrical fields and the structure of water-retaining medias were studied. Three different shapes of polarized electric fields in ranges of 0-100 V/cm and 0-10 kHz are used as the source of electric voltage. The effect of electroosmotic process with respect to the structural variation is estimated by filling the electroosmotic reactor with the glass beads in 0.18 mm, 0.35 mm and 1.2 mm in diameters. 6% of water removal is obtained in the simulating electroosmotic reactor of glass beads. The estimated energy consumption in the simulating electroosmotic was 330~490 cal/g-water.

• Journal of Ginseng Research
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• v.47 no.3
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• pp.469-478
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• 2023

Background: Nitrogen (N) is an essential macronutrient for plant growth and development. To support agricultural production and enhance crop yield, two major N sources, nitrate and ammonium, are applied as fertilizers to the soil. Although many studies have been conducted on N uptake and signal transduction, the molecular genetic mechanisms of N-mediated physiological roles, such as the secondary growth of storage roots, remain largely unknown. Methods: One-year-old P. ginseng seedlings treated with KNO₃ were analyzed for the secondary growth of storage roots. The histological paraffin sections were subjected to bright and polarized light microscopic analysis. Genome-wide RNA-seq and network analysis were carried out to dissect the molecular mechanism of nitrate-mediated promotion of ginseng storage root thickening. Results: Here, we report the positive effects of nitrate on storage root secondary growth in Panax ginseng. Exogenous nitrate supply to ginseng seedlings significantly increased the root secondary growth. Histological analysis indicated that the enhancement of root secondary growth could be attributed to the increase in cambium stem cell activity and the subsequent differentiation of cambium-derived storage parenchymal cells. RNA-seq and gene set enrichment analysis (GSEA) revealed that the formation of a transcriptional network comprising auxin, brassinosteroid (BR)-, ethylene-, and jasmonic acid (JA)-related genes mainly contributed to the secondary growth of ginseng storage roots. In addition, increased proliferation of cambium stem cells by a N-rich source inhibited the accumulation of starch granules in storage parenchymal cells. Conclusion: Thus, through the integration of bioinformatic and histological tissue analyses, we demonstrate that nitrate assimilation and signaling pathways are integrated into key biological processes that promote the secondary growth of P. ginseng storage roots.

• Journal of Convergence for Information Technology
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• v.12 no.3
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• pp.280-285
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• 2022

In order to ensure maximum capacity at a given frequency resource, the number of antennas must be increased. The increase in antennas means that such guaranteed channel resources can be used as an increase in channel capacity by aquiring another channel resource. In order to aggregate antennas in such a situation where there are a plurality of antennas, a problem of miniaturizing and integrating antennas must be accompanied. In this situation, in order to efficiently allocate channel resources and antenna resources in limited device resources, the problem of antenna selection and user scheduling was considered and solved together. By numerical simulation results, the proposed algorithm was proven to effectively reduce 34 % power consumption in averagewith increase in antennas.

• The Bulletin of The Korean Astronomical Society
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• v.46 no.2
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• pp.38.1-38.1
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• 2021

Dust polarization depends on the physical and mechanical properties of dust, as well as the properties of local environments. To understand how dust polarization varies with grain mechanical properties and the local environment, in this paper, we model the wavelength-dependence polarization of starlight and polarized dust emission by aligned grains by simultaneously taking into account grain alignment and rotational disruption by radiative torques (RATs). We explore a wide range of the local radiation field and grain mechanical properties characterized by tensile strength. We find that the maximum polarization and the peak wavelength shift to shorter wavelengths as the radiation strength U increases due to the enhanced alignment of small grains. Grain rotational disruption by RATs tends to decrease the optical-near infrared polarization but increases the ultraviolet polarization of starlight due to the conversion of large grains into smaller ones. In particular, we find that the submillimeter (submm) polarization degree at 850㎛(P850) does not increase monotonically with the radiation strength or grain temperature (Td), but it depends on the tensile strength of grain materials. Our physical model of dust polarization can be tested with observations toward star-forming regions or molecular clouds irradiated by a nearby star, which have higher radiation intensity than the average interstellar radiation field. Finally, we compare our predictions of the P850-Td relationship with Planck data and find that the observed decrease of P850 with Td can be explained when grain disruption by RATs is accounted for, suggesting that interstellar grains unlikely to have a compact structure but perhaps a composite one. The variation of the submm polarization with U (or Td)can provide a valuable constraint on the internal structures of cosmic dust

• The Bulletin of The Korean Astronomical Society
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• v.44 no.2
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• pp.57.4-57.4
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• 2019

BITSE is a project of balloon-borne experiments for a next-generation solar coronagraph developed by a collaboration with KASI and NASA. The coronagraph is built to observe the linearly polarized brightness of solar corona with a polarization camera, a filter wheel, and an aperture door. For the observation, the coronagraph is supported by the power distribution unit (PDU), a pointing system WASP (Wallops Arc-Second Pointer), telemetry & telecommand system SIP (Support Instrument Package) which are developed at NASA's Goddard Space Flight Center, Wallops Flight Facility, and Columbia Scientific Balloon Facility. The BITSE Command and Data Handling (C&DH) system used a cost-off-the-shelf electronics to process all data sent and received by the coronagraph, including the support system operation by RS232/422, USB3, Ethernet, and digital and analog signals. The flight software is developed using the core Flight System (cFS) which is a reusable software framework and set of reusable software applications which take advantage of a rich heritage of successful space mission of NASA. The flight software can process encoding and decoding data, control the subsystems, and provide observation autonomy. We developed a python-based testing framework to improve software reliability. The flight software development is one of the crucial contributions of KASI and an important milestone for the next project which is developing a solar coronagraph to be installed at International Space Station.

• Genomics & Informatics
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• v.21 no.1
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• pp.2.1-2.14
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• 2023

Microglia, similar to peripheral macrophages, are the primary immune cells of the central nervous system (CNS). Microglia exist in the resting state in the healthy CNS, but can be activated and polarized into either M1 or M2 subtypes for immune defense and the maintenance of CNS homeostasis by multiple stimuli. Several long noncoding RNAs (lncRNAs) mediate human inflammatory diseases and neuropathologies by regulating their target genes. However, the function of common lncRNAs that contribute to microglial activation remains unclear. Thus, we used bioinformatic approaches to identify common lncRNAs involved in microglial activation in vitro. Our study identified several lncRNAs as common regulators of microglial activation. We identified 283 common mRNAs and 53 common lncRNAs during mouse M1 microglial activation processes, whereas 26 common mRNAs and five common lncRNAs were identified during mouse M2 microglial activation processes. A total of 648 common mRNAs and 274 common lncRNAs were identified during the activation of human M1 microglia. In addition, we identified 1,920 common co-expressed pairs in mouse M1 activation processes and 25 common co-expressed pairs in mouse M2 activation processes. Our study provides a comprehensive understanding of common lncRNA expression profiles in microglial activation processes in vitro. The list of common lncRNAs identified in this study provides novel evidence and clues regarding the molecular mechanisms underlying microglial activation.