• Title/Summary/Keyword: point of impact

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Application of Response Surface Method as an Experimental Design to Optimize Coagulation Tests

  • Trinh, Thuy Khanh;Kang, Lim-Seok
    • Environmental Engineering Research
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    • v.15 no.2
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    • pp.63-70
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    • 2010
  • In this study, the response surface method and experimental design were applied as an alternative to conventional methods for the optimization of coagulation tests. A central composite design, with 4 axial points, 4 factorial points and 5 replicates at the center point were used to build a model for predicting and optimizing the coagulation process. Mathematical model equations were derived by computer simulation programming with a least squares method using the Minitab 15 software. In these equations, the removal efficiencies of turbidity and total organic carbon (TOC) were expressed as second-order functions of two factors, such as alum dose and coagulation pH. Statistical checks (ANOVA table, $R^2$ and $R^2_{adj}$ value, model lack of fit test, and p value) indicated that the model was adequate for representing the experimental data. The p values showed that the quadratic effects of alum dose and coagulation pH were highly significant. In other words, these two factors had an important impact on the turbidity and TOC of treated water. To gain a better understanding of the two variables for optimal coagulation performance, the model was presented as both 3-D response surface and 2-D contour graphs. As a compromise for the simultaneously removal of maximum amounts of 92.5% turbidity and 39.5% TOC, the optimum conditions were found with 44 mg/L alum at pH 7.6. The predicted response from the model showed close agreement with the experimental data ($R^2$ values of 90.63% and 91.43% for turbidity removal and TOC removal, respectively), which demonstrates the effectiveness of this approach in achieving good predictions, while minimizing the number of experiments required.

Impact of Trend Estimates on Predictive Performance in Model Evaluation for Spatial Downscaling of Satellite-based Precipitation Data

  • Kim, Yeseul;Park, No-Wook
    • Korean Journal of Remote Sensing
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    • v.33 no.1
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    • pp.25-35
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    • 2017
  • Spatial downscaling with fine resolution auxiliary variables has been widely applied to predict precipitation at fine resolution from coarse resolution satellite-based precipitation products. The spatial downscaling framework is usually based on the decomposition of precipitation values into trend and residual components. The fine resolution auxiliary variables contribute to the estimation of the trend components. The main focus of this study is on quantitative analysis of impacts of trend component estimates on predictive performance in spatial downscaling. Two regression models were considered to estimate the trend components: multiple linear regression (MLR) and geographically weighted regression (GWR). After estimating the trend components using the two models,residual components were predicted at fine resolution grids using area-to-point kriging. Finally, the sum of the trend and residual components were considered as downscaling results. From the downscaling experiments with time-series Tropical Rainfall Measuring Mission (TRMM) 3B43 precipitation data, MLR-based downscaling showed the similar or even better predictive performance, compared with GWR-based downscaling with very high explanatory power. Despite very high explanatory power of GWR, the relationships quantified from TRMM precipitation data with errors and the auxiliary variables at coarse resolution may exaggerate the errors in the trend components at fine resolution. As a result, the errors attached to the trend estimates greatly affected the predictive performance. These results indicate that any regression model with high explanatory power does not always improve predictive performance due to intrinsic errors of the input coarse resolution data. Thus, it is suggested that the explanatory power of trend estimation models alone cannot be always used for the selection of an optimal model in spatial downscaling with fine resolution auxiliary variables.

Patient Safety Program and Safety Culture (투약간호 중심의 환자안전 프로그램 개발 및 평가)

  • Kim, Young-Mee;Kim, Se-Young;Kim, Min-Young;Kim, Ju-Hee;Lee, Suk-Kyoung;Jang, Mi-Kyung
    • Journal of Korean Academy of Nursing Administration
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    • v.16 no.4
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    • pp.455-465
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    • 2010
  • Purpose: To determine the impact of the Patient Safety Program on the safety culture of nursing department. Methods: Patient Safety Program focused on medication safety was launched by QI team and patient safety committee. Patient Safety Program was composed of the establishment of improved reporting system as s way to learn from error, 'Patient Safety Guard' movement, and continuous education for medication safety. With one group pretest-posttest design, nurses' perception of the safety culture were measured with self-administered questionnaire. Subjects were all nurses and managers in nursing department of a tertiary teaching hospital in Seoul. Collected data from survey was statistically analyzed using t-test. Results: Patient Safety Program had been continued for 20 months in participation of all nurses and managers. Safety culture was improved (pretest=2.84, posttest=2.90, p<.001; 4 point scale). Conclusions: This study indicates that there has been a statistically significant increase in the nurses' perception of safety culture. These findings suggest that Patient Safety Program had made great contribution toward system wide safety culture in the hospital. To improve safety culture, leadership supports and flexibility to apply tailored interventions to the hospital were required necessarily.

An Essay on the Possibility of New Seoul International Airport as a Regional Hub (신공항(新空港)의 허브공항화(空港化)에 관한 소고(小考))

  • Kim, Jong-Seok
    • The Korean Journal of Air & Space Law and Policy
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    • v.5
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    • pp.303-320
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    • 1993
  • The construction of New Seoul International Airport is under way despite much controversy. Among much discussed, but not well-formulated controversy is the possibility of the airport as a hub in the North Asia Region. This paper specifies the factors which render it possible for an airport to be a regional hub. Then each factor is applied to the new airport to see whether it can function as a hub airport. Also examined is the qualitative cost and benefit calculation related to the hub function. The usual discussion has missed one big point of cost side of hub function in the belief that the hub only produces benefits to the national economy where the airline and airport industry belong; earlier-than-expected congestion and the necessity to expand the airport sufficiently enough to accommodate the increasing air demand. An airport as a hub is determined by several factors; geographical location ; economic status of the country where the airport belongs ; bilateral air service agreements according to which the airlines can exercise the route rights; the airport charges which directly influence the cost structure of the carriers ; international aviation and airport related policies of each country in the region ; airport capacity etc. The tentative implications of this paper are the followings; first, the new airport is able to function as a regional hub in the transpacific routes which connect Asian countries and North America. That is, directional hubbing by the airlines is implicated; second, the main benefits may be accrued to american airlines exercising all the route rights in the Asian region; third, the governmental effort to make the new airport a regional hub must take caution in optimizing the hubbing level (% of transitting passengers and freight) between the benefits and the costs. Further Studies may include optimal level of hubbing for the new airport and, quantification of the impact of the new airport on the national economy depending on the degree of hubbing.

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Comparative Genome-Scale Expression Analysis of Growth Phase-dependent Genes in Wild Type and rpoS Mutant of Escherichia coli

  • Oh, Tae-Jeong;Jung, Il-Lae;Woo, Sook-Kyung;Kim, Myung-Soon;Lee, Sun-Woo;Kim, Keun-Ha;Kim, In-Gyu;An, Sung-Whan
    • Proceedings of the Korean Society for Applied Microbiology Conference
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    • 2004.06a
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    • pp.258-265
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    • 2004
  • Numerous genes of Escherichia coli have been shown to growth phase-dependent expression throughout growth. The global patterns of growth phase-dependent gene expression of E. coli throughout growth using oligonucleotide microarrays containing a nearly complete set of 4,289 annotated open reading frames. To determine the change of gene expression throughout growth, we compared RNAs taken from timecourses with common reference RNA, which is combined with equal amount of RNA pooled from each time point. The hierarchical clustering of the conditions in accordance with timecourse expression revealed that growth phases were clustered into four classes, consistent with known physiological growth status. We analyzed the differences of expression levels at genome level in both exponential and stationary growth phase cultures. Statistical analysis showed that 213 genes are shown to, growth phase-dependent expression. We also analyzed the expression of 256 known operons and 208 regulatory genes. To assess the global impact of RpoS, we identified 193 genes coregulated with rpoS and their expression levels were examined in the isogenic rpoS mutant. The results revealed that 99 of 193 were novel RpoS-dependent stationary phase-induced genes and the majority of those are functionally unknown. Our data provide that global changes and adjustments of gene expression are coordinately regulated by growth transition in E. coli.

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An Experimental Study for the Improvement of Ventilation Conditions and Effectiveness in the Manufacturing Industry by Increasing the Mixing Factor (K-Factor) (혼합계수(K-Factor) 증가에 따른 사업장의 환기 조건 및 효율 개선에 관한 연구)

  • Lee, Yun-ho;Lee, Seokwon;Lee, Kyoungho;Kim, Hyunwook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.29 no.3
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    • pp.343-350
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    • 2019
  • Objectives: This study aims to identify whether ventilation conditions and their effectiveness can be significantly improved in an experimental chamber by increasing the mixing factor (K-Factor). Methods: In a chamber with a volume of $1m^3$, air velocity was measured at six different points with four roof fans in the upper part of the chamber being operated in order. The impact of the ventilation conditions was analyzed when the flow rates were increasing and the first inlet of the chamber was either open or closed. Smoke patterns were also observed at four corner points where ventilation was limited. Kruskal Wallis and Mann-Whitney tests were performed to compare air velocities measured in the chamber. Results: The air velocities measured at only the third point increased significantly from $0.03{\pm}0.03m/s$ (door open) and $0.05{\pm}0.06m/s$ (door closed) with two fans, $0.08{\pm}0.08m/s$ with three fans, and $0.09{\pm}0.09m/s$ with four fans operating (p<0.05). However, air velocities at the four corner points did not significantly increase. Smoke patters also showed that the open inlet of the chamber had no effect on improvement of ventilation conditions and effectiveness. Conclusions: In this study, the air velocities at six points in the chamber did not significantly increase despite the increase in the mixing factor and flow rates of ventilation in the controlled environment. Therefore, the inflow of outdoor air throughout an open inlet and installation of a forced ventilation system can potentially increase the indoor air velocity and improve ventilation condition without an increase in the mixing factor.

The Impact of Grit on University Student's Core Competency in Dental Hygiene Students

  • Park, Soo-Auk;Cho, Young-Sik
    • Journal of dental hygiene science
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    • v.19 no.3
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    • pp.170-180
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    • 2019
  • Background: Recently, competency-based education has been reorganized in the dental hygiene curriculum. In education, non-cognitive factors are emphasized. Grit, the non-cognitive ability to persevere to achieve an individual's long-term goals, is emerging. This study aims to identify the degree of grit and core competencies in students and to investigate the relationship between them and the factors that affect these core competencies. Methods: This study was conducted using 350 dental hygiene students who were randomly assigned a structured questionnaire to complete. The final analysis included 321 students. The survey contents evaluated grit, core competencies, and general characteristics. The difference in the degree of grit and core competencies in conjunction with the general characteristics of the subjects was analyzed using the t-test/Mann Whitney U-test and the ANOVA/Kruskal-Wallis H test. Multiple regression analysis was then conducted to determine the factors affecting the core competencies of the subjects. Results: The difference of 'grit' according to general characteristics was statistically significant in 'major satisfaction', 'relationship', 'perceived academic achievement', 'grade point average (GPA)'. The difference in 'core competency' according to general characteristics was statistically significant in 'grade', 'department selection', 'major satisfaction', 'relationship', 'perceived academic achievement', 'GPA'. Among the sub-areas of 'grit', 'perseverance of effort' showed a high correlation with 'core competency' and was statistically significant. As a result of regression analysis, 'major satisfaction', 'perceived academic achievement' and 'grit' of dental hygiene students had a statistically significant influence on 'core competency'. Meanwhile, 'GPA' was not seen to be statistically significant in 'core competency'. Conclusion: Grit, a non-cognitive factor, had a statistically significant effect on core competency, while the effects on GPA, a cognitive factor, were not statistically significant. Among the sub-factors of grit, 'perseverance of effort' had a statistically significant effect on 'problem-solving competency' and 'academic competency', which are 'core competency' sub factors.

Effects of mechanical intervention on cutaneous sensory change and pressure pain threshold in the same spinal segment of myofascial pain

  • Kim, Do Hyung;Lee, Su-Hyun;Lee, Byoung Hee
    • Physical Therapy Rehabilitation Science
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    • v.8 no.1
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    • pp.15-21
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    • 2019
  • Objective: The purpose of this study was to identify whether cutaneous sensory (CS) changes induced by mechanical intervention (MI) increases the trigger point threshold of the same spinal segment as well as to investigate the relationship between the amounts of change in CS pressure pain thresholds (PPT). Design: Randomized controlled trial. Methods: Thirty-nine persons with myofacial pain (MFP) were recruited in this experiment. The subjects consisted of 20 men and 19 women (age 20-39). MI was applied on the subjects using the Graston technique for 5 minutes to induce CS changes. The CS changes were measured with sensory tests by using the Von Frey Filament, and PPT changes were estimated by using the pressure threshold meter. For the observation of sensory and PPT changes with time, the test was conducted for 15 minutes including a pre, post, and after intervention session. Results: CS threshold increased significantly when MI was applied (p<0.001). On the same spinal segment, changes in the right infraspinatus PPT was observed (p<0.001) but the PPT changes in other muscles were not significantly different. Furthermore, the control group CS and PPT were not significantly different. In addition, regression analysis showed that the CS changes have a larger impact on PPT in the same spinal segment (p<0.001). Conclusions: CS changes induced by MI make to change PPT on the same spinal segment. In other words, it is possible to identify PPT changes following CS changes except for the muscle which belongs to a different spinal segment. Therefore, application of MI is necessary for the CS changes in the same spinal segment. Furthermore, it can be useful in the clinical fields as a method of providing pain control and increasing the PPT.

Comparative Analysis of the Intake Volume, Perception Volume, and Satiety Rate of an Augmented Rice Bowl with an Elevated Bottom (바닥을 올린 밥그릇의 식품 섭취량, 인지 섭취량 및 포만도에 대한 비교 분석)

  • Jung, Eun-Jin;Kim, Dong Geon;Chang, Un-Jae
    • Journal of the Korean Dietetic Association
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    • v.28 no.1
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    • pp.19-29
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    • 2022
  • This study examined the impact of perceived volume on satiety using 400 g kimchi fried rice in a normal rice bowl (Normal-400), 300 g kimchi fried rice in an augmented rice bowl with an elevated bottom (Illusion-300 and 300 g kimchi fried rice in a normal rice bowl (Normal-300). Thirty-six healthy women took part in this study once a week for three weeks. The Normal-400 (1st week), Illusion-300 (2nd week), and Normal-300 (3rd week) bowls were used to served kimchi fried rice to the same participants over three consecutive weeks. After each lunch, the consumption volume of fried rice, perception volume, and satiety rate were measured. The consumption volume of the fried rice was 313.8 g with the Normal-400, 248.9 g with the Illusion-300 and 240.2 g with the Normal-300. The perceived volume on an estimated five-point scale was 4.0 with the Normal-400, 4.1 with the Illusion-300 and 2.4 with the Normal-300. We compared the post-meal satiety of perceptually equal but quantitatively different amounts of food served in two different bowls (Normal-400 vs Illusion-300) and found that the participants felt equally full with both bowls despite having consumed significantly more food from the Normal-400. We also compared the post-meal satiety of perceptually different but quantitatively equal amounts of food in two different bowls (Illusion-300 vs Normal-300) and discovered that the subjects felt significantly fuller with the Illusion-300 although similar amounts of food were consumed from the two bowls. These two comparisons showed that visual cues play a critical role in determining satiety and that perceived volume is perhaps more important than the actual volume of consumed food, while in determining the level of fullness.

The Process of Determining of Pro-Social Tourism Behavior Intention according to the Perception of the Risk of COVID-19 : Utilizing the Norm Activation Model (코로나19 위험인식에 따른 친사회적 관광행동의도 결정과정 : 규범 활성화 모델을 활용하여)

  • Jeon, Chang-Young;Song, Woon-Gang;Yang, Hee-Won
    • Asia-Pacific Journal of Business
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    • v.12 no.2
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    • pp.145-159
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    • 2021
  • Purpose - The purpose of this study is to identify the preceding factors that form pro-social tourism behavior intent in a pendemic situation and to present theoretical and practical implications for the role of individuals for a safe tourism environment. Design/methodology/approach - This study conducted an analysis by collecting 420 valid questionnaires targeting citizens who have lived in Korea continuously for more than one year. For the analysis, a confirmatory factor analysis (CFA) and a structural equation model (SEM) were used, and a multi-group confirmatory factor analysis (MCFA) and a multi-group structural equation model (MSEM) were used to verify the difference by age group. Findings - First, cognitive and affective risk perception for Covid-19 had a significant (+) effect on the ascription of responsibility to tourists, and affective risk perception and ascription of responsibility had a significant (+) effect on personal norms. Second, personal norms have been shown to have a significant (+) influence on prosocial tourism behavior intention, and prosocial tourism behavior intention has a significant (+) influence on WTP on safety tourism. Research implications or Originality - Tourism behavior in a pendemic situation can affect the spread of infection. In this respect, this study attempted to confirm how moral norms affect pro-social tourism behavior from a personal point of view. In addition, we tried to present practical implications by identifying the impact of personal norms on willing to pay for a safe tourism environment.