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Association between the Brain-Derived Neurotropic Factor and Attention Deficit Hyperactivity Disorder (BDNF가 ADHD의 병인과 치료에 미치는 영향)

  • Kang, Na Ri;Song, Jae Min;Kwack, Young-Sook
    • Korean Journal of Biological Psychiatry
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    • v.25 no.2
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    • pp.21-30
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    • 2018
  • Attention deficit hyperactivity disorder (ADHD) is a common childhood psychiatric disorder. Recently, it has been suggested that brain-derived neurotropic factor (BDNF) may play a role in the pathogenesis of ADHD. Our aim of this review is to understand the physiological functions of BDNF and its potential relationship with ADHD and therapeutic approaches of ADHD. Searches were conducted in Pubmed and Research Information Service System (RISS). In this review, we summarized important literatures for the physiological functions of BDNF in neurodevelopment, change of serum BDNF level in ADHD, association of BDNF polymorphism and ADHD and potential association of treatment of ADHD with serum BDNF level. Further studies are required to more clearly understand the source and the role of BDNF in ADHD and to develop BDNF based-ADHD treatement.

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Noun versus Verb Bias Revisited

  • ChangSong, You-kyung;Pae, So-Yeong
    • Speech Sciences
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    • v.10 no.1
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    • pp.131-141
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    • 2003
  • Recently, researchers have been debating whether Korean children exhibit a verb bias or not. Since verbs are perceptually and structurally more salient in Korean language, it has been questioned whether these differences in the Korean make a difference in the pattern of noun and verb acquisition of Korean children. Although language structures may vary between Korean and English, universal cognitive constraints play an important role in early vocabulary acquisition. Several recent studies have examined the noun and verb acquisition of Korean children. However, their conclusions regarding the noun versus verb bias have still been inconclusive. In this paper, previous studies investigating Korean children's noun versus verb bias are examined. Methodological issues are mentioned and results were reinterpreted as favoring the noun bias for one-year-old Korean children.

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Applicability and Methods of Lean Production in Railway Transportation Organization: A Case Study of Urumqi Railway Bureau in China

  • Li, Hong-Chang;Rong, Chao-He;Song, De-Xi
    • International Journal of Railway
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    • v.1 no.2
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    • pp.45-58
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    • 2008
  • The concept of lean production originated and was applied mainly to manufacture industries Even proven successful with such companies as Toyota, lean production has to be combined railway transportation production in order to bring its function into full play. The paper analyzes for applicability of lean production in railway transportation production organization, puts forward implementation methods such as transportation resource integration, station-zone organization, dispatch command optimization, railway performance evaluation index system, etc., and makes an exemplification study of lean production of Urumqi Railway Bureau in China, which testifies the applicability and efficiency of railway lean production.

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How Effective Is the Injection Therapy in Foot and Ankle Disorder? (족부족관절 질환에서 주사 치료는 얼마나 효과가 있는가?)

  • Song, Ha Heon
    • Journal of Korean Foot and Ankle Society
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    • v.25 no.1
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    • pp.10-16
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    • 2021
  • Evidence-based papers on the treatment of some chronic tendinopathy or ligament lesions using an injection in foot and ankle disorders have been reported, but there are few reports on the treatment of acute ankle ligament injury. On the other hand, some papers have reported a faster return to play for injection therapy that combines RICE (Rest, Icing, Compression, and Elevation) treatment and rehabilitation. Injection therapy can be used as an additional treatment for ankle ligament injury. Rather than having narrow-minded thinking about these treatments, it is important to make efforts to verify the safety and precautions of treatment and recognize them as a category of normal treatment. Continuous analysis and monitoring of these treatments can satisfy patients whose needs are changing rapidly.

Framework analysis of Speed-running : Towards a Comparison Between the Normal Gameplayer and Speed Runners (스피드 러닝 프레임워크 분석 : 일반 게임플레이어와 스피드 러너 간의 비교를 중심으로)

  • Thiago, Araujo Silva;Song, Seung-Keun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.24 no.2
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    • pp.337-339
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    • 2020
  • Speed-run is a gameplay style in what the player tries to finish the game as quickly as possible. The purpose of this study is to observe and analyze the difference between a normal player and a speed runner in a speed run to better understand their interaction with the game and to extrapolate the applications of the analyzed frameworks to scenarios that extent normal gameplay. For this purpose, MDA (Mechanic, Dynamic, Aesthetics) and DPE (Experience, Design, Play) were used. As a result, the average player was found to focus on aesthetics or affects while the speed runner focused on mechanics and gameplay.

Platelet Anti-aggregating and Anti-oxidative Activities of 12-O-(4'-O-methyl-galloyl)-bergenin, a Novel Compound Isolated from Crassula cv. "Himaturi"

  • Lee, Yong-Yook;Jang, Dae-Song;Jin, Jing-Ling;YunChoi, Hye-Sook
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.193.3-194
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    • 2003
  • Platelets play critical roles in both hemostasis and thrombosis. It was reported that platelet aggregation is associated with an increase in superoxide production and can be inhibited by hydroxyl radical scavengers. In the course of our search for the anti-platelet, anti-coagulant and/or anti-oxidative components from plants, the MeOH extract of Crassula cv. "Himaturi" (Crassulaceae) was observed to have both anti-aggregatory and anti-coagulant effects. A novel compound, 12-O-(4'-O-methyl-galloyl)-bergenin (1), was isolated as an active component from the EtOAC soluble fraction. (omitted)

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Review of ginsenosides targeting mitochondrial function to treat multiple disorders: Current status and perspectives

  • Huang, Qingxia;Gao, Song;Zhao, Daqing;Li, Xiangyan
    • Journal of Ginseng Research
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    • v.45 no.3
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    • pp.371-379
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    • 2021
  • Mitochondrial dysfunction contributes to the pathogenesis and prognosis of many common disorders, including neurodegeneration, stroke, myocardial infarction, tumor, and metabolic diseases. Ginsenosides, the major bioactive constituents of Panax ginseng (P. ginseng), have been reported to play beneficial roles in the molecular pathophysiology of these diseases by targeting mitochondrial dysfunction. In this review, we first introduce the types of ginsenosides and basic mitochondrial functions. Then, recent findings are summarized on different ginsenosides targeting mitochondria and their key signaling pathways for the treatment of multiple diseases, including neurological disorders, cancer, heart disease, hyperglycemia, and inflammation are summarized. This review may explain the common targets of ginsenosides against multiple diseases and provide new insights into the underlying mechanisms, facilitating research on the clinical application of P. ginseng.

Microwave-treated Expandable Graphite Granule for Enhancing the Bioelectricity Generation of Microbial Fuel Cells

  • Kim, Minsoo;Song, Young Eun;Li, Shuwei;Kim, Jung Rae
    • Journal of Electrochemical Science and Technology
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    • v.12 no.3
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    • pp.297-301
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    • 2021
  • Microbial fuel cells (MFCs) convert chemical energy to electrical energy via electrochemically active microorganisms. The interactions between microbes and the surface of a carbon electrode play a vital role in capturing the respiratory electrons from bacteria. Therefore, improvements in the electrochemical and physicochemical properties of carbon materials are essential for increasing performance. In this study, a microwave and sulfuric acid treatment was used to modify the surface structure of graphite granules. The prepared expandable graphite granules (EGG) exhibited a 1.5 times higher power density than the unmodified graphite granules (1400 vs. 900 mW/m3). Scanning electron microscopy and Fourier transform infrared spectroscopy revealed improved physical and chemical characteristics of the EGG surface. These results suggest that physical and chemical surface modification using sulfuric acid and microwave heating improves the performance of electrode-based bioprocesses, such as MFCs.

Structure and Function of Tight Junctions in the Skin (피부에서의 치밀이음의 구조와 기능)

  • Song, Mee;Baek, Ji Hwoon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.48 no.2
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    • pp.181-188
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    • 2022
  • The skin protects the body from excessive water loss and the invasion of harmful substances, such as chemicals and microbes. The stratum corneum, is recognized as a very important physical barrier. However, in recent years evidence emerged that tight junctions (TJ) might also play a crucial role in barrier function of the skin. In the present study, TJ proteins including transmembrane proteins and plaque proteins, skin permeability barrier function and skin diseases of TJ were reviewed.

Perceptions of Corporate Social Responsibility and Implications for the Nonprofit Sector

  • Jihyeon Song;Seongho An;Jiwon Suh
    • Journal of Contemporary Eastern Asia
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    • v.22 no.1
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    • pp.26-48
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    • 2023
  • While corporate social responsibility (CSR) has been considered an important philanthropic support for nonprofits worldwide, little is known about how perceptions of CSR are associated with actual CSR practices that may benefit nonprofit organizations in different institutional contexts. This study applies stakeholder theory to examine how South Korean firms perceive CSR outcomes, and how these perceptions lead to different CSR practices. We constructed a panel dataset using two waves of the Giving Korea survey of CSR and two additional sources. The results indicate that perceived CSR outcomes may play a critical role in CSR practices: 1) the more financial performance is perceived as an outcome, the more will be donated; 2) the more organizational culture is perceived as an outcome, the greater the engagement in employee volunteering; and 3) the more reputation is perceived as an outcome, the more nonprofit organizations are supported. From the findings, we discuss theoretical implications and provide suggestions for nonprofit organizations.