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Effects of the Damping Ratios of Power Generators on Power Efficiency of an Ocean Renewable Energy Converter Utilizing Flow Induced Vibrations of Two Circular Cylinders (두 원형실린더의 유동유발진동 현상을 이용하는 해양신재생에너지 변환기의 발전 효율에 발전기의 감쇠비가 미치는 영향에 관한 연구)

  • Kim, Eun Soo;Park, Hongrae;Kim, Dong Hwi;Baek, Hyung-min;Bernitsas, Michael M.
    • New & Renewable Energy
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    • v.16 no.1
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    • pp.31-40
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    • 2020
  • Most countries in the world are trying to reduce the use of fossil fuels in the production of electricity and replace them with renewable energy technologies. In Korea, there are abundant ocean renewable energy sources that will play an important role in power generation in the future. This paper introduces a new tidal energy converter utilizing flow induced vibration (FIV), which can work efficiently, even in the currents slower than 1.0m/s. All tests were conducted at the Marine Renewable Energy Laboratory at the University of Michigan to examine the effects of the damping ratio of the electric generators on the power outputs and power efficiencies. In these tests, two identical circular cylinders were used, and passive turbulence controllers were applied to the surface of the cylinders to enhance the FIV. The experimental results showed that by using the two cylinders in the FIV, the power output and efficiency reached up to 31 W and 36%, respectively. In particular, the results showed that the power efficiency was higher at the relatively low flow speed (4

Molecular and biochemical characterization of a novel actin bundling protein in Acanthamoeba

  • Alafag Joanna It-itan;Moon Eun-Kyung;Hong Yeon-Chul;Chung Dong-Il;Kong Hyun-Hee
    • Parasites, Hosts and Diseases
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    • v.44 no.4 s.140
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    • pp.331-341
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    • 2006
  • Actin binding proteins play key roles in cell structure and movement particularly as regulators of the assembly, stability and localization of actin filaments in the cytoplasm. In the present study, a cDNA clone encoding an actin bundling protein named as AhABP was isolated from Acanthamoeba healyi, a causative agent of granulomatous amebic encephalitis. This clone exhibited high similarity with genes of Physarum polycephalum and Dictyostelium discoideum, which encode actin bundling proteins. Domain search analysis revealed the presence of essential conserved regions, i.e., an active actin binding site and 2 putative calcium binding EF-hands. Transfected amoeba cells demonstrated that AhABP is primarily localized in phagocytic cups, peripheral edges, pseudopods, and in cortical cytoplasm where actins are most abundant. Moreover, AhABP after the deletion of essential regions formed ellipsoidal inclusions within transfected cells. High-speed co-sedimentation assays revealed that AhABP directly interacted with actin in the presence of up to $10{\mu}M$ of calcium. Under the electron microscope, thick parallel bundles were formed by full length AhABP, in contrast to the thin actin bundles formed by constructs with deletion sites. In the light of these results, we conclude that AhABP is a novel actin bundling protein that is importantly associated with actin filaments in the cytoplasm.

A Study on the Image Changes of an Eye Shape according to Eyelash Design (속눈썹디자인에 따른 눈 형태의 이미지변화 연구)

  • Park, Jeong Shin
    • Journal of Fashion Business
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    • v.21 no.1
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    • pp.58-73
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    • 2017
  • The purpose of this study was to examine the need of the eyelash design area and the changes of an eye image according to eyelash design. Methodology included both a theoretical research and an empirical research. The theoretical research reviewed previous researches and technical books. The empirical research divided eye shapes, complemented the defect of eye shapes, and examined resulting image changes. A mechanical way was performed for treatment because it was more efficient than a manual way. A J-curl type was used. Eye length was divided into five and the point was determined. The length and density of curl were changed in each point to maximize a treatment effect. As a result, eye images were changed as follows. First, round eyes became stable. Slit eyes became vivid and soft. Wide-set eyes became intelligent and narrow-set eyes became smooth. Large eyes were naturally gradated and small eyes became larger. Double-eyelid eyes became stable and elegant and single-eyelid eyes became gentle and soft. Bulging eyes became easy and soft and sunken eyes became smooth. Peaked eyes became gentle and soft and sleepy eyes became strong and vivid. Based on the findings, eyelash design can play a role in changing an image according to eye shapes. In particular, a speed eyelash extension device to extend eyelash can reduce working hours and gradate only by angle control. It can complement the defect of eyes according to the design of each shape and change into a better image.

Improving Customer Satisfaction Management using the Satisfied Customer Segmentation based on Latent Class Analysis (Latent Class Analysis 기반의 만족 고객 세분화를 이용한 고객만족경영 향상 방안)

  • Song, Ki-Jeong;Seo, Kwang-Kyu;Ahn, Beum-Jun
    • The Journal of the Korea Contents Association
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    • v.11 no.12
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    • pp.386-394
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    • 2011
  • Recently it is difficult to draw an improvement for customer satisfaction because the ratio of satisfied customers increases in customer satisfaction survey. In addition, the effectiveness of practical application of customer satisfaction survey decreases due to its constitution limitation on its data analysis. In order to solve these problems, it is necessary to develop a novel research to identify the strategy meanings and find dissatisfied factors of satisfied customers using the satisfied customers' reclassification. This study focuses on the satisfied customer segmentation based on Latent Class Analysis (LCA). The case study with high-speed internet service customers show that the satisfied customers are divided into three subgroups using LCA and we draw meaning results such as satisfaction and dissatisfaction factors through analyzing each group. This study is expected to play the role as the groundwork for the revitalization of customer satisfaction survey as well as improving customer satisfaction management.

The Taste Compounds of Sun Dried Ascidian, Cynthia roretzi (건조(乾燥)멍게의 정미성분(呈味成分))

  • Sung, Nak-Ju;Lee, Jong-Ho;Chung, Seung-Yong
    • Journal of Nutrition and Health
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    • v.11 no.3
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    • pp.13-20
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    • 1978
  • Changes of free amino acids, nucleotides and their related compounds as taste compounds during sun drying of ascidian Cynthia roretzi, were analyzed by amino acid autoanalyzer and high speed liquid chromatography. In fresh ascidian, the results showed that 5'-UMP $(12.1\;{\mu}mole/g)$ was dominant and the content of cytosine, 2', 3'-CMP, 2', 3'-GMP, hypoxanhtine, 5'-AMP,5'-IMP were 5.8, 3.4, 3.1, 2,3, 1.7 and $1.3\;{\mu}mole/g$ ondry base respectively. 5'-IMP, 2', 3'-CMP and 2', 3'-GMP tended to degrade slowly and 5'-AMP, cytosine and 5'-UMP were decreased rapidly while hypoxanthine were increased remarkably during the sun drying. In dried ascidian, the content of hypoxanthine was the highest, 7.2 mole/g on dry base, whereas that of 5'-AMP $(0.5\;{\mu}mole/g)$) and 5'-IMP $(0.9\;{\mu}mole/g)$ were lower. Glutamic acid, alanine and serine were dominant amino acid in the fresh extracts, having 22.4% (611.3mg%, on dry qase), 19.8% (540.5mg%) and 14.8% (402.8mg%) of the total amino acid content respectively. The content of tyrosine, histidine, lysine, methionine, isoleucine and valine were low, and proline, phenylalanine were detected in trace amount. The free amino acid were not changed in composition but the increase of total free amino acid was approximately 116.8mg% during sun drying. In sun dried ascidian, glutamic acid (691.0mg, on dry base), alanine (641.3mg%), serine (469.5mg%), threonine (234.8mg%) and glycine (206.3mg%) were dominant amino acid. It is believed that glutamic acid, serine, alanine, threonine, glycine and hypoxanthine play an important role as taste compounds in sun dried ascidian.

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Implementation of a Samsulnori Ensemble System using a Touch Interface (터치 인터페이스를 이용한 사물놀이 협주 시스템 구현)

  • Lee, Yong-Woong;Cho, Jong-Sik;Ju, Jong-Gil;Lee, Ho-Chul;Hwang, Jeong-Hwan;Shin, Chang-Sun
    • The Journal of the Korea Contents Association
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    • v.10 no.6
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    • pp.213-221
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    • 2010
  • Recently, as the scale of the cultural content business market is being growed, it required that we should introduce the Korean music culture which is unique and competitive cultural contents to the worldwide. This paper proposes a Samulnori Ensemble System (SES), using a touch interface which plays the Korean traditional musical instruments. A SES consists of the Control Device which supports touch functions, the Performance Manager that detects signals from the Control Device and plays a melody, and the Communication Manager making a ensemble among the possible devices. Also, using the Network Time Protocol which is part of Synchronization Manager can be paly different speed communication environments. We utilized multi-touch functions to operate the system. We also implemented multi-touch interface and multi-play with other player for fun and interesting who are not interested Samulnori.

Applications of DNA Microarray in Disease Diagnostics

  • Yoo, Seung-Min;Choi, Jong-Hyun;Lee, Sang-Yup;Yoo, Nae-Choon
    • Journal of Microbiology and Biotechnology
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    • v.19 no.7
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    • pp.635-646
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    • 2009
  • Rapid and accurate diagnosis of diseases is very important for appropriate treatment of patients. Recent advances in molecular-level interaction and detection technologies are upgrading the clinical diagnostics by providing new ways of diagnosis, with higher speed and accuracy. In particular, DNA microarrays can be efficiently used in clinical diagnostics which span from discovery of diseaserelevant genes to diagnosis using its biomarkers. Diagnostic DNA microarrays have been used for genotyping and determination of disease-relevant genes or agents causing diseases, mutation analysis, screening of single nucleotide polymorphisms (SNPs), detection of chromosome abnormalities, and global determination of posttranslational modification. The performance of DNA-microarray-based diagnosis is continuously improving by the integration of other tools. Thus, DNA microarrays will play a central role in clinical diagnostics and will become a gold standard method for disease diagnosis. In this paper, various applications of DNA microarrays in disease diagnosis are reviewed. Special effort was made to cover the information disclosed in the patents so that recent trends and missing applications can be revealed.

The Massive Blooms of Gonyaulax polygramma (Gonyaulacales, Dinophyceae) in the Southern Coastal Areas of Korea in Summer, 2009 (2009년 남해안 전역에 발생된 고니아룩스 적조에 관한 연구)

  • Cho, Eun-Seob
    • Journal of Environmental Science International
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    • v.20 no.12
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    • pp.1521-1531
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    • 2011
  • This study was carried out to determine the characteristics of the marine environment, including nutritional content, in order to clearly understand the outbreaks of Gonyaulax polygramma in the southern coastal areas in August, 2009. Samples were collected at 13 sites and water temperature and salinity were measured using a CTD. Field surveys were twice: the first between August 5-7, the second between August 22-24. The cell density of G. polygramma was 6,500-10,000 cells $ml^{-1}$ during the $1^{st}$ survey, whereas during the $2^{nd}$ survey the range of the cells was recorded from 8,000 to 12,500 cells $ml^{-1}$. Cochlodinium polykrikoides ranged from 0 to 105 cells $l^{-1}$ during the field survey. In water environments, the majority stations during the $1^{st}$ survey showed a nearly homogeneous water column below $1^{\circ}C$ in temperature, as well as similar profiles of salinity. However, the stratification between the surface and bottom was observed in the $2^{nd}$ survey. Regarding nutrients, Dissolved Inorganic Nitrogen (DIN) in the surface ranged from 0.144 to 0.236 mg $l^{-1}$ during the $1^{st}$ survey, and 0.082-0.228 mg $l^{-1}$ during the $2^{nd}$ survey. DIP (Dissolved Inorganic Phosphorus) did not show any difference in concentration between the $1^{st}$ and $2^{nd}$ survey. During August of 2009, the wind speed in the southern waters remained at around ${\leq}2\;m\;s^{-1}$ for about 60% of time, and there was very little precipitation during the month. Irradiance of ${\geq}10$ hr was shown in the late of August. It is thought that a low level of DIN and salinity play an important role as an essential factor for rapid growth, wide distribution and longer duration of red tide in G. polygramma.

Epoxy-based Interconnection Materials and Process Technology Trends for Semiconductor Packaging (반도체 패키징용 에폭시 기반 접합 소재 및 공정 기술 동향)

  • Eom, Y.S.;Choi, K.S.;Choi, G.M.;Jang, K.S.;Joo, J.H.;Lee, C.M.;Moon, S.H.;Moon, J.T.
    • Electronics and Telecommunications Trends
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    • v.35 no.4
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    • pp.1-10
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    • 2020
  • Since the 1960s, semiconductor packaging technology has developed into electrical joining techniques using lead frames or C4 bumps using tin-lead solder compositions based on traditional reflow processes. To meet the demands of a highly integrated semiconductor device, high reliability, high productivity, and an eco-friendly simplified process, packaging technology was required to use new materials and processes such as lead-free solder, epoxy-based non cleaning interconnection material, and laser based high-speed processes. For next generation semiconductor packaging, the study status of two epoxy-based interconnection materials such as fluxing and hybrid underfills along with a laser-assisted bonding process were introduced for fine pitch semiconductor applications. The fluxing underfill is a solvent-free and non-washing epoxy-based material, which combines the underfill role and fluxing function of the Surface Mounting Technology (SMT) process. The hybrid underfill is a mixture of the above fluxing underfill and lead-free solder powder. For low-heat-resistant substrate applications such as polyethylene terephthalate (PET) and high productivity, laser-assisted bonding technology is introduced with two epoxy-based underfill materials. Fluxing and hybrid underfills as next-generation semiconductor packaging materials along with laser-assisted bonding as a new process are expected to play an active role in next-generation large displays and Augmented Reality (AR) and Virtual Reality (VR) markets.

HOXB5 Directly Regulates the Expression of IL-6 in MCF7 Breast Cancer Cells

  • Kim, Jie Min;Lee, Ji-Yeon;Kim, Myoung Hee
    • Biomedical Science Letters
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    • v.23 no.3
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    • pp.272-276
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    • 2017
  • HOX genes are transcription factors that play important roles in body patterning and cell fate specification during normal development. In previous study, we found aberrant overexpression of HOXB5 in breast cancer tissues and cell lines, and demonstrated that HOXB5 is important in regulation of cell proliferation, tamoxifen resistance, and invasiveness through the epithelial-mesenchymal transition (EMT). Although the relationship between HOXB5 and phenotypic changes in MCF7 breast cancer cells has been studied, the molecular function of HOXB5 as a transcription factor remains unclear. IL-6 has been reported to be involved in not only inflammation but also cancer progression, which is characterized by the increase of growth speed and invasiveness of tumor cells. In this study, we selected Interleukin-6 (IL-6) as HOXB5 putative downstream target gene and discovered that HOXB5 transcriptionally up-regulated the expression of IL-6 in HOXB5 overexpressing MCF7 cells. The upstream region (~1.2 kb) of IL-6 promoter turned out to contain several putative HOX consensus binding sites. Chromatin immunoprecipitation assay confirmed that HOXB5 directly binds to the promoter region of IL-6 and positively regulated the expression of IL-6. These data all together, indicate that HOXB5 promotes IL-6 transcription by actively binding to the putative binding sites located in the upstream region of IL-6, which enable to increase its promoter activity in MCF7 breast cancer cells.