• Title/Summary/Keyword: plasma application

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Pharmacokinetics of Omeprazole from Rectal Suppositories (오메프라졸 함유 직장좌제의 약물속도론적 연구)

  • 이창현;황성주;권광일;이계주
    • YAKHAK HOEJI
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    • v.37 no.5
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    • pp.427-436
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    • 1993
  • The pharmacokinetics and relationship between in vitro dissolution and in vivo fraction absorbed were investigated after intravenous(iv) injection of omeprazole(OMZ), oral administration of OMZ capsules and rectal administration of 8 types of suppositories. The plasma concentration of OMZ (C$_{p}$)-time (t) curve after iv. administration fitted a two-compartment open model and the equation which best fitted the pharmacokinetics of OMZ was $C_{p}$ = 13.936 $e^{-8.78t}$+2.973 $e^{-0.716t}$. The bioavailabilities of OMZ in Witepsol H15 base (Supp-2) and PEG 4000 base (Supp-6) suppositories were 40.7% and 33.4%, respectively, which are higher(p<0.001) than 13% of oral administration of capsule. The avoidance fractions of the first-pass metabolism for Supp-2 and Supp-6 suppositiories were 31.8% and 23.4%, respectively, suggesting that the rectal application of OMZ may be a more adequate route of administration than oral one.

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Scribing and cutting a sapphire wafer by laser-induced plasma-assisted ablation

  • Lee, Jong-Moo
    • Proceedings of the Optical Society of Korea Conference
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    • 2000.02a
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    • pp.224-225
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    • 2000
  • Transparent and hard materials such as sapphire are used for many industrial applications as optical windows, hard materials on mechanical contact against abrasion, and substrate materials for opto-electronic semiconductor devices such as blue LED and blue LD etc. The materials should be cut along the proper shapes possible to be used for each application. In case of blue LED, the blue LED wafer should be cut to thousands of blue LED pieces at the final stage of the manufacturing process. The process of cutting the wafer is usually divided into two steps. The wafer is scribed along the proper shapes in the first step. It is inserted between transparent flexible sheets for easy handling. And then, it is broken and split in the next step. Harder materials such as diamonds are usually used to scribe the wafer, while it has a problem of low depth of scribing and abrasion of the harder material itself. The low depth of scribing can induce failure in breaking the wafer along the scribed line. It was also known that the expensive diamond tip should be replaced frequently for the abrasion. (omitted)

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Application of methylene blue color test for the detection of inherited susceptibility to hemolysis of Korean native cattle (한우(韓牛)의 선천성용혈감수성검사(先天性溶血感受性檢査)에 대한 methylene blue 청색소실시험법(靑色消失試驗法)의 적용(適用))

  • Cho, Jong-hoo
    • Korean Journal of Veterinary Research
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    • v.28 no.2
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    • pp.327-329
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    • 1988
  • Blood samples were obtained from Korean native cattle and dairy cattle of Holstein species in the slaughter house and methylene blue color tests were performed for the detection of the inherited susceptibitity to hemolysis. Glucose-6-phosphate dehydrogenase activities expressed as the optical density obtained by methylene blue color test were the highest as 0.54 in male Korean cattle, 0.62 in female Korean cattle and 0.72 in dairy cattle of Holstein species. Percent hemolysis, packed cell volume and plasma protein contents were measured and compaired with relation to the results of methylene blue color test and no correlation were observed in each.

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A Study on the Material Property and Application of the Si-doped MgO Layer (Si가 첨가된 MgO의 기초 물성 및 응용 연구)

  • Cho, Sung-Yong;Park, Chung-Hoo;Yu, Yun-Sik;Lee, Don-Kyu
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.58 no.12
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    • pp.2441-2445
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    • 2009
  • The effects of Si -doped MgO have been investigated in order to improve the material properties of the MgO protective layer in plasma display panels. A small amount of Si is added to the MgO pellet while the MgO layer is being deposited by using an electron-beam evaporation method. Both the surface characteristics of the protecting layer and the electro-optical properties of 4 in. test panels are investigated, such as XRD patterns, SEM images, firing and sustain voltages, secondary electron emission coefficient($\gamma$), luminance, luminous efficacy and lifetime. The firing and sustain voltage are minimized when Si concentration is 0.038%, where the luminance and luminous efficacy increase up to 17% and 26% compared with that of the pure MgO film, separately, and lifetime also shows good characteristics.

Gliding arc plasma application for PFCs gas decomposition (PFCs가스 분해처리를 위한 글라이딩 아크 플라즈마 응용)

  • No, I.J.;Shin, P.K.;Park, D.W.;Kim, H.K.;Lee, S.H.;Park, J.K.;Kang, D.H.;Kim, J.S.
    • Proceedings of the KIEE Conference
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    • 2008.07a
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    • pp.1354-1355
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    • 2008
  • 교류 펄스전압을 이용한 글라이딩 아크 플라즈마를 이용하여 PFCs(Perfluoro compounds) 가스의 일종인 $CF_4$ $SF_6$, $NF_3$를 가스분해하는 연구를 실시하였다. 반응기 양전극 사이에 인가되는 전압은 10kV로 고정하고 각각의 가스의 유량을 조절하여 분해한후 FT-IR을 통해 각각의 가스의 분해율과 분해후 가스내 성분을 스펙트럼을 이용하여 분석하였다. 유량이 낮아질수록 분해율은 좋아졌고 $SF_6$$NF_3$의 경우 99%이상의 높은 분해율에 도달하였을 뿐 아니라 대표적인 난분해 가스로 손꼽히는 $CF_4$의 경우 82%이상의 분해율을 확인하였다.

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Fabrication of OLED using low cost transparent conductive thin films (저가격 투명전극을 이용한 OLED의 제작)

  • Lee, B.J.;Shin, P.K.;You, D.H.;Ji, S.H.;Lee, N.H.;Park, K.S.
    • Proceedings of the KIEE Conference
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    • 2008.07a
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    • pp.1281-1282
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    • 2008
  • Low cost TCO(Transparent Conductive oxide) thin films were prepared by 3" DC/RF magnetron sputtering systems. For the AZO preparation processes a 99.99% AZO target (Zn: 98 wt.%, $Al_2O_3$: 2 wt.%) was used. In order to verify feasibility of the AZO thin films to organic light emitting device (OLED) application, test organic light emitting device was fabricated based on AZO as TCO, TPD as hole transporting layer (HTL), Alq3 as both emitting layer (EML) and electron transporting layer (ETL), and aluminium as cathode, where the both ITO and AZO surfaces were treated using $O_2$ RF plasma. The I-V characteristics of the AZO/TPD/Alq3/Al OLEDs were evaluated. As the results, the performance of the OLEDs with AZO as transparent conducting anode could be useable.

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Radiation Induced Cystitis and Proctitis - Prediction, Assessment and Management

  • Mallick, Supriya;Madan, Renu;Julka, Pramod K;Rath, Goura K
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5589-5594
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    • 2015
  • Cystitis and proctitis are defined as inflammation of bladder and rectum respectively. Haemorrhagic cystitis is the most severe clinical manifestation of radiation and chemical cystitis. Radiation proctitis and cystitis are major complications following radiotherapy. Prevention of radiation-induced haemorrhagic cystitis has been investigated using various oral agents with minimal benefit. Bladder irrigation remains the most frequently adopted modality followed by intra-vesical instillation of alum or formalin. In intractable cases, surgical intervention is required in the form of diversion ureterostomy or cystectomy. Proctitis is more common in even low dose ranges but is self-limiting and improves on treatment interruption. However, treatment of radiation proctitis is broadly non-invasive or invasive. Non-invasive treatment consists of non-steroid anti-inflammatory drugs (NSAIDs), anti-oxidants, sucralfate, short chain fatty acids and hyperbaric oxygen. Invasive treatment consists of ablative procedures like formalin application, endoscopic YAG laser coagulation or argon plasma coagulation and surgery as a last resort.

A Study on the Machining Characteristics fur Micro Barrier Ribs by using Micro Endmilling (마이크로 엔드밀에 의한 미세격벽가공의 가공특성에 관한 연구)

  • 민승기;이선우;이동주;이응숙;제태진
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.11 no.3
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    • pp.14-20
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    • 2002
  • Recently, miniaturization and mass production are the main trends in manufacturing fields. Therefore, ultraprecision machining and MEMS technology have been taken more 7md more important position in machining of microparts. Micro endmilling is one of the prominent technology that has wide spectrum of application field ranging from duo parts to micro products, such as PDP md IT components, in precision products manufacturing. However, decreasing of burr is significant problem in making smooth and precise parts in micro endmilling. This paper shows removal characteristics of burr generated by micro endmilling process. This results satisfies micro endmilling for micro barrier ribs of heights is $50{\mu}m$, $100{\mu}m$, $200{\mu}m$, $300{\mu}m$, and observation from of burr. Additionally, it is necessary to understand the formation mechanism of burr of micro barrier ribs to iud proper decreasing method.

A Study of Thermoelectric Material for Waste Heat Recovery (배열회수 발전용 열전소재 기초연구)

  • Kim, Ho-Young;Kim, Cham
    • Proceedings of the KSME Conference
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    • 2008.11a
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    • pp.175-180
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    • 2008
  • Thermoelectric materials convert temperature difference to electric power for power generation and vice versa for refrigeration. Recent advances in enhancing the thermoelectric figure-of-merit shed light on efficient power generation from the waste heat available in industries and vehicles. Nanoscale phenomena with both nanoscale constituent-embedded bulk samples and nanoscale materials proving enhanced thermoelectric performance have been widely reviewed. Bulk materials of crystal-orientation and nano-structured particle embedding seem to promise a higher thermoelectric figure-of-merit and an effective power generation application. As a preliminary study, Si-Ge nanocomposite was prepared with spark plasma sintering method and its properties were examined.

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Protective Coatings for the Elements of Ships Power Plants which Use Sea Water

  • Minaev, Alexander N.;Gnedenkov, S.V.;Sinebryukhov, S.L.;Mashtalar, D.V.
    • Journal of Advanced Marine Engineering and Technology
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    • v.36 no.3
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    • pp.341-350
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    • 2012
  • In this paper we observe the protective coatings carbon for steel, aluminium and titanium alloys were obtained by plasma electrolytic oxidation (PEO) under unipolar and bipolar conditions. The anticorrosion properties and the thermal stability of the surface layers were studied by electrochemical impedance spectroscopy and potentiodynamic polarization. It was found that the application of the bipolar PEO mode enables one to synthesize the surface layers that possess enhanced anticorrosion and mechanical properties. results of research of antiscale PEO - coatings for marine power equipment are presented. The combined method of prevention of corrosion and scale formation was tested at the industrial plants of Russian Shipyard "Zvezda".