• Journal of Oral Medicine and Pain
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• v.47 no.3
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• pp.161-166
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• 2022

Oral lichen planus (OLP) is a chronic oral mucosal disease affecting the buccal cheek, tongue, palate, lip, and gingival mucosa. Lesions in the gingiva make it difficult to control dental plaque due to pain. As a result, the disease is often accompanied by gingivitis or periodontitis. If OLP and dental plaque are not properly managed, the patient's periodontal condition will worsen. Thus, clinicians treating OLP should emphasize periodic visits and dental plaque control. Here, we report the management of a patient who struggled with OLP for 20 years and discuss the importance of periodic regular observations and active periodontal management.

• Journal of Periodontal and Implant Science
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• v.7 no.1
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• pp.22.2-22.2
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• 1977

• Journal of Korean society of Dental Hygiene
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• v.11 no.2
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• pp.293-301
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• 2011

Objectives : The aim of the trial was to study the effect of plaque control(tooth brushing instruction) for oral health improvement on periodontitis patients. Methods : 30 patients(35~65 years) with advanced periodontal disease were subjected to a baseline examination including assessment of oral hygiene status(O'leary index), gingival condition(bleeding). the assessment were repeated after 2, 4, 6 weeks. cognitive, behavioral and clinical outcomes were assessed in the primary care setting by questionnaire and clinical oral examination. Results : The oral hygiene status expressed as the individual mean percentage of tooth surfaces with plaque 59.3% at baseline and 21.2% after 6 weeks(p<0.001). The gingival bleeding status expressed as the individual mean point of interdental papilla 3.8 at baseline and 1.9 after 6 weeks(p<0.001). Also, the patients self-assessment about correct tooth brushing behavior was 3.9(5-point likert scales), satisfaction of plan practices 4.1(5-point likert scales), efficacy of tooth brushing instruction 8.7(10-point likert scales). Patients wanted to continuous participation. Conclusions : A verification of effect after individualized oral health instruction and repeated dental plaque control represented to significance on plaque control score, oral care practice and oral health recognition. The important oral care step against periodontal disease is to establish good oral health habits. Also, oral health behavior recognition is more important for the practice of oral health. Therefore professional plaque control and tooth brushing instruction absolutely need in improving oral health.

• Journal of Periodontal and Implant Science
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• v.34 no.1
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• pp.61-70
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• 2004

연구 목적: 3개월 간의 잇솔질에 따른 칫솔의 마모의 정도와 양상을 관찰하고, 이를 이용한 잇솔질 시의 치태 제거능력의 변화를 평가하여 일반적으로 권장되고 있는 3개월 주기의 칫솔 교체 주기의 근거를 실제 임상적으로 확인해보고자 하였다. 연구방법: 치주적으로 건강한 치과 대학생 52명을 대상으로 설문지를 통해 잇솔질 습관을 조사하고, 치석제거술을 시행하고 실험기간 동안 동일한 칫솔과 치약을 사용하게 하였다. 1주일 후와 2달과 3달째에 구강 내를 erythrosine으로 염색한 후 6개의 Ramfjord 치아의 plaque score를 측정하고, 3달 동안 사용한 칫솔을 수거하여 brushing surface area의 면적으로 마모도를 평가하였다. 결과: 6명이 탈락하였고 전체 부위의 plaque score는 1주 때와 비교하여 2,3 개월의 값이 통계학적으로 유의한 차이가 없었으나, 치간 부위의 plaque score는 3개월의 plaque score와 상관관계는 약하였다. 교체 주기, 잇솔질 횟수, 시간 등의 잇솔질 습관과 마모도의 연관성도 없었지만, 잇솔질 시간과 3개월째의 plaque score의 상관관계는 유의성 있는 결과를 보였다. 결론: 3개월 동안 사용한 칫솔의 치간 부위 치태제거 능력은 감소하였으며, 이의 임상적 영향에 대한 장기간의 연구가 필요하겠다.

• The Journal of the Korean dental association
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• v.54 no.12
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• pp.1035-1044
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• 2016

Purpose : The purpose of this study was to compare the plaque removal effects of vacuum oral cleaner developed for the patients with limited mobility with those of manual toothbrushes and high pressure injection oral cleaner (dental water jet). Meterials and methods : Thirty human subjects were measured with Patient Hygiene Performance index (PHP index) and O'Leary index before and after the use of toothbrush, high pressure injection oral cleaner and vacuum oral cleaner. These three different oral hygiene methods were conducted with seven-day intermittence. Then the statistical analysis was carried out to define plaque removal rate of three different oral hygiene methods (${\alpha}=.05$). Results : According to the efficacy analysis of plaque removal before and after the oral cleaning using each of three methods, significant reduction in plaque after the treatment compared to the previous state when using toothbrush, high pressure injection oral cleaner, and vacuum oral cleaner was observed (P < 0.001). PHP index of tooth brushing was higher than that of the high pressure injection oral cleaner, while PHP index of vacuum oral cleaner did not show significant difference from either of the other two methods. There was no significance difference in O'Leary index among the three methods. Conclusion : Effect of plaque removal using the vacuum oral cleaner is comparable to that of manual tooth brush or high pressure injection oral cleaner, so it will be helpful for self-oral hygiene care of the patients with limited mobility.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5359-5364
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• 2015

Background: Multiple complex pathways are operable in the evolution of cutaneous T cell lymphomas (CTCLs). These pathways involve interaction between neoplastic T cells and cells of the immune system (especially dendritic cells and the non-malignant T cells). Granulysin is a proinflammatory antimicrobial peptide which has an immune alarmin function, activating dendritic cells, as well as an active role in tumor immunology and prognosis. FOXP3+ regulatory T cells Tregs are an important player in the immune system. Much controversy is found in the literature about the role of Tregs in CTCL. Aim: The present study aimed to investigate the expression of granulysin and FOXP3 in mycosis fungoides (MF), its precursor lesion large plaque parapsoriasis and its leukemic form ;$s\acute{e}ezary$ syndrome (SS). Materials and Methods: Immunohistochemical expression of granulysin and FOXP3 were assessed in lesional skin biopsies taken from 58 patients (4 large plaque parapsoriasis, 48 MF and 6 SS). Results: Granulysin positivity was cytoplasmic and higher in MF than in parapsoriasis en plaque and higher in the more advanced stages of MF (p<0.001). All groups showed significant differences between each other except between MF tumor stage and SS. FOXP3 positivity was nuclear and higher in early stage MF (plaque and patch stages) than in tumor stages and SS (p<0.001). However the FOXP3 count was lower in parapsoriasis en plaque than in other stages of MF. All the groups showed significant differences between each other except between parapsoriasis and SS and between patch and plaque stages of MF. Conclusions: The present study supports a role for granulysin in MF progression and proposes a novel hypothesis about the effect of FOXP3 +veTregs in the suppression of the activity of the neoplastic cells in MF.

• Journal of Microbiology and Biotechnology
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• v.26 no.12
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• pp.2141-2147
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• 2016

As one of the most complex human-associated microbial habitats, the oral cavity harbors hundreds of bacteria. Halitosis is a prevalent oral condition that is typically caused by bacteria. The aim of this study was to analyze the microbial communities and predict functional profiles in supragingival plaque from healthy individuals and those with halitosis. Ten preschool children were enrolled in this study; five with halitosis and five without. Supragingival plaque was isolated from each participant and 16S rRNA gene pyrosequencing was used to identify the microbes present. Samples were primarily composed of Actinobacteria, Bacteroidetes, Proteobacteria, Firmicutes, Fusobacteria, and Candidate phylum TM7. The ${\alpha}$ and ${\beta}$ diversity indices did not differ between healthy and halitosis subjects. Fifteen operational taxonomic units (OTUs) were identified with significantly different relative abundances between healthy and halitosis plaques, and included the phylotypes of Prevotella sp., Leptotrichia sp., Actinomyces sp., Porphyromonas sp., Selenomonas sp., Selenomonas noxia, and Capnocytophaga ochracea. We suggest that these OTUs are candidate halitosis-associated pathogens. Functional profiles were predicted using PICRUSt, and nine level-3 KEGG Orthology groups were significantly different. Hub modules of co-occurrence networks implied that microbes in halitosis dental plaque were more highly conserved than microbes of healthy individuals' plaque. Collectively, our data provide a background for the oral microbiota associated with halitosis from supragingival plaque, and help explain the etiology of halitosis.

• The Journal of Advanced Prosthodontics
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• v.4 no.4
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• pp.179-186
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• 2012

PURPOSE. The aim of this study was to evaluate the efficiency of manual polishing over autoglazed and overglazed porcelain and their effect on plaque accumulation. MATERIALS AND METHODS. Thirty-six porcelain discs were fabricated out of which 18 each was subjected for autoglazing and overglazing. Half surface of the discs was left intact; the remaining half was roughened with medium grit diamond bur. Roughened surfaces were repolished by porcelain polishing kits (Shofu, DFS, Eve). All the surfaces were evaluated by the perthometer and SEM. Six discs from each sample were placed in human volunteer's mouth for 72 hours to evaluate the plaque accumulation. Acquired data was subjected to ANOVA comparative evaluation. RESULTS. Roughened surfaces had average roughness value of $2.88{\pm}0.1935{\mu}m$. The repolished surfaces by porcelain correction kits Shofu, DFS and Eve, average roughness value reduced to $0.6250{\pm}0.1036$, $0.9192{\pm}0.0953$, $0.9017{\pm}0.1305$ respectively. Autoglazed and overglazed surfaces showed the mean roughness value (Ra) of $0.4217{\pm}0.0685$, $0.3450{\pm}0.0729$. SEM study showed the improved surfaces when subjected for polishing. Plaque accumulation percentage was the highest on roughened surface ($93.83{\pm}6.2552%$), followed by porcelain discs polished by commercial kits. Autoglazed surfaces found to be the best surfaces with the least plaque accumulation ($0.5237{\pm}0.4209%$). CONCLUSION. All the polishing kits used in the study reduced the average roughness by approximately 77%. Corrected porcelain surfaces should ideally be reglazed, alternatively, polish the surfaces before final cementation.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.29 no.4
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• pp.309-320
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• 2007

Purpose: This study was to evaluate the removal effect on artificial plaque from RBM treated implant surfaces that are exposed due to peri-implantitis. Materials and methods: Artificial plaque with Streptococcus mutans and acquired pellicle adhered to RBM treated implant discs. Study materials divided into one control and six test groups. In test groups, physical and chemical methods used to remove plaques. Prophyflex, Professional Mechanical Tooth Cleaning (PMTC) and interdental brush as mechanical treatments and 0.1% Chlorhexidine, Citric acid, HCl tetracycline as a chemical treatment were used. To analyses the study, disc weight was measured for remaining plaque quantities and SEM(Scanning Electronic Microscope) findings was taken for evaluation of surfaces. Results: 1. In weight changes, there was significant difference between each treatment group and the control group (p<0.05). Therefore all treatment methods using this study have good ability for remove plaques. 2. In weight changes, there was no significant difference between mechanical and chemical group, and there were no significant differences between each groups (p>0.05). 3. SEM findings after mechanical treatment disclosed as follows; Prophyflex group looked like sound implant surface, and there were some paste on implant surface at PMTC group, and there were some artificial plaque at interdental brush group. 4. SEM findings after chemical treatment disclosed as follows; there were some dark lesions which were supposed as the product from Streptococcus mutans at Chlorhexidine, Citric acid and HCl tetracycline groups. Conclusion: All six methods using in this study have good ability to remove artificial plaque on RBM treated implant. According to SEM findings, prophyflex is a superior method for removing of dental plaque among test groups.

• Journal of Korean society of Dental Hygiene
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• v.9 no.1
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• pp.125-139
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• 2009

Objective : This study was performed in order to provide basic data for halitosis prevention and establish a device to efficiently eliminate halitosis and to analyze the factors that affect the halitosis. Methods : Oral examination on the Gingival index, CPITN, Tongue Plaque index, and OHI-S as well as halitosis measurement among 293 rural residents. Results : Gingival index was high at mild on female and at moderate on male(p=0.025). Sorting the result by age, mild was 54.1% in the 40s, and moderate was 49.5%, 42.0% and 70.0% each in the 50s, 60s, and the 70s(p=0.005). The need for dental plaque management was 100%. The need for scaling was high with 78.3%, 93.0%, 89.9%, and 90.0% each for the 40s, 50s, 60s, and 70s. The need for complex periodontal treatment was also high with 32.4%, 47.5%, 48.7% and 60.0%, each for the 40s, 50s, 60s, and 70s(p=0.050). The highest bad condition for OHI-S was 69.5%, and good being 18.9%, and very bad being 11.6%. For moderate tongue plaque index was 74.4% as the highest. As the level of education increased, the slight tongue plague was increased, but in contrast, the moderate and higher tongue plague index was decreased(p=0.010). OG under 50ppm was 61.1% on male and OG over 50ppm was 50.9% on female(p=0.041). In OG over 50ppm, CPITN was 52.1% and 41.9% in scaling and complex periodontal treatment group(p=0.018). OHI-S, in bad and very bad condition with OG, over 50ppm, was 48.7% and 46.9%(p=0.019). The higher tongue plague index showed significant amount of increase at OG and EG above 50ppm(p=0.006). $NH_3$, as the tongue plaque index increased, the wider range of distribution was shown(p=0.000). As for the multiple regression analysis result, there have been selected females and tongue plaque index as factors affecting OG. There have been selected age and tongue plaque index as factors affecting EG and there have been selected females as factors affecting on $NH_3$. Conclusions : With the aforementioned results in mind, the status of halitosis among rural residents is considered to bare a close relation with oral environments. we have to focus on correct tooth brushing methods and tongue brushing, with using tongue cleaner to remove fur of tongue plaque. Also, in order to analyze exactly the factors of individual halitosis, we need continuous and systematic study.