• Annals of Clinical Neurophysiology
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• v.14 no.2
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• pp.53-58
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• 2012

For the last decades, molecular genetics has achieved great advances that the genes on the list of inherited muscle diseases are piling up. Those diseases of overlapping clinico-pathologic findings are now understood with discrete molecular pathogeneses. We are facing an exciting era that the long-waited gene therapy may eventually come true. Skipping of dystrophin exon 51 is on successful clinical trials, which will benefit about 13% of the children suffering from Duchenne muscular dystrophy. Exon skipping is under active investigation to expand the candidates. Hopefully it may cover majority of Duchenne muscular dystrophy mutations and some of other diseases. Adeno-associated virus is one of the most versatile tools for gene transfer. It may overcome the limitation of exon skipping. Here we review exon skipping technique of Duchenne muscular dystrophy and briefly discuss the other strategies being studied to cure inherited muscle diseases.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.48 no.5
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• pp.658-663
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• 1999

2D sliced CT images hardly express the human disease in a space. This space expression can be reconstructed into 3D image by piling up the CT sliced image in succession. In medical image, in order to get the reconstructed 3D images, expensive system or much calculation time is needed. But by changing the method of reconstruction procedure and limit the range, the reconstruction time could be reduced. In this study, to reduce the processing time and memory, we suggested a method of interpolation and ray casting processing at the same time in a limited range. Such a limited range processing have advantages that we could reduce the unnecessary interpolation and ray casting. Through a experiment, it is founded that the reconstruction time and the memory was much reduced.

• Journal of the Korean Society for Precision Engineering
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• v.21 no.9
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• pp.196-203
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• 2004

SL(Stereolithography) part is made by piling up thin layers which causes the stair stepping effect at the surface of SL parts. The effect brings about excessive surface roughness and cuts down the merits of using SL part. Hence, additional post-machining finishing such as traditional grinding is required. But the traditional post-machining is detrimental to part geometry and time consuming. In this study, therefore, a paraffin coating and grinding post-machining is newly proposed to improve the surface quality of SL fart. The paraffin which has suitable properties for the proposed post-machining is coated all over the part surface. By grinding the only over-coated paraffin based on boundary of the SL part surface, the surface roughness can be improved without any damage on the part. Also, it is verified that SL part finished by the proposed post-machining process can be applied for rapid tooling as pattern through manufacturing silicon rubber molding and casting test.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.13 no.1
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• pp.47-57
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• 2003

In this paper, we firstly evaluate the resistance of the reduced 5-round version of the block cipher CIKS-1 against linear cryptanalysis(LC) and show that we can attack full-round CIKS-1 with \ulcorner56-bit key through the canonical extension of our attack. A feature of the CIKS-1 is the use of both Data-Dependent permutations(DDP) and internal key scheduling which consist in data dependent transformation of the round subkeys. Taking into accout the structure of CIKS-1 we investigate linear approximation. That is, we consider 16 linear approximations with p=3/4 for 16 parallel modulo $2^2$ additions to construct one-round linear approximation and derive one-round linear approximation with the probability P=1/2+$2^{-17}$ by Piling-up lemma. Then we present 3-round linear approximation with 1/2+$2^{-17}$ using this one-round approximation and attack the reduced 5-round CIKS-1 with 64-bit block by LC. In conclusion we present that our attack requires $2^{38}$chosen plaintexts with a probability of success of 99.9% and about $2^{67-7}$encryption times to recover the last round key.(But, for the full-round CIKS-1, our attack requires about $2^{166}$encryption times)

• Journal of the Korea Society of Computer and Information
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• v.18 no.1
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• pp.185-192
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• 2013

The development of hardware, popularization of 3D graphics software could get to easily use 3d graphics tool in the school. And learning difficulties of a shape section increased through more being enforced a shape section of an elementary school. Thus we try to improve learning effectiveness in a shape section using Sketech Up software. To do this, we analyzed existing studies, classified 3D graphics software, provided the selection criteria of vector graphics software. And we explained how to select 3D graphics software. We selected and reorganized the shape contents to use Sketch Up, which make and rotate 3D figures, understand aspects of a shape. And we inserted the content about piling 3D figures in the beginning state of the curriculum. we composed 10 periods and practiced our reorganized curriculum to the teaching and learning using Sketch Up. And we conducted before & after survey to check out t-verified. And we acquired meaningful results statistically. Thus applying Sketch Up to the shape learning can be analyzed effectively.

• Journal of the Korean Institute of Landscape Architecture
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• v.30 no.1
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• pp.1-10
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• 2002

The purpose of this article is to examine land use change in the fringe area of a metropolitan city through multi-temporal data analysis. Change detection has been regarded as one of the most important applications for utilization of remotely sensed imageries. Conventionally, two images were used for change detection, and Arithmetic calculators were generally used on the process. Meanwhile, multi-temporal change detection for a large number of images has been carried out. In this paper, a digital land-use map and three Landsat TM data were utilized for the multi-temporal change detection Each urban area map was extracted as a base map on the process of multi-temporal change detection. Each urban area map was converted to bit image by using boolean logic. Various urban change types could be obtained by stacking the urban area maps derived from the multi-temporal data using Geographic Information System(GIS). Urban change type map was created by using the process of piling up the bit images. Then the urban change type map was compared with each land cover map for the change detection. Dalseo-gu of Daegu city and Hwawon-eup of Dalsung-gun, the fringe area of Daegu Metropolitan city, were selected for the test area of this multi-temporal change detection method. The districts are adjacent to each other. Dalseo-gu has been developed for 30 yeais and so a large area of paddy land has been changed into a built-up area. Hwawon-eup, near by Dalseo-gu, has been influenced by the urbanization of Dalseo-gu. From 1972 to 1999, 3,507.9ha of agricultural area has been changed into other land uses, while 72.7ha of forest area has been altered. This agricultural area was designated as a 'Semi-agricultural area'by the National landuse Management Law. And it was easy for the preserved area to be changed into a built-up area once it would be included as urban area. Finally, the method of treatment and management of the preserved area needs to be changed to prevent the destruction of paddy land by urban sprawl on the urban fringe.

• Journal of the Korean Recycled Construction Resources Institute
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• v.2 no.2
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• pp.68-75
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• 2006

The total production of the smelted copper reaches 450,000 tons per year, and the production of copper-related goods grows year by year owing to the extension of facilities and the development of production techniques. On the other hand, the volume of slag discharges by-produced at the time of copper smelting process is also on trend of increase. The by-produced copper smelting slag amounts to 700,000 tons a year, which is one and half times of the total smelted copper production. Accordingly nobody disagrees that comprehensive researches on how to deal with and how to reuse the accumulated smelting copper slag have to be encouraged. Even though the possible uses of the copper smelting slag have being made on various levels at present as materials for iron powder cement, sand-blasting and fire-proofing rock wool, but a considerable volume of the slag is abandoned as unnecessary by burying or piling up in careless in the open ground.

• Journal of Korean Library and Information Science Society
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• v.12
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• pp.133-160
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• 1985

In college or university libraries, the data of dissertations is one of the important academic information data. But traditional cataloging rules of dissertations and the method of operation is not only didn't unify but also fit to actual circumstances of library. This reason make librarians waste of time and the situation about piling up of unprocessed data don't make library services properly. In this papers, to analyze the above mentioned problems, I have investigated with questionaries about actual examples of construction methods of call number and item describing form of dissertations which is being used now in every college library in Korea. With the replied 61 questionaries which was compared with and investigated to merits and faults about library itself, I have showed revision ways. The characteristics of the revision ways are the followings. 1) Deleted informal and unmeaning descriptions and simplified describing. 2) Recommended to operating one or two kinds describing items which are only necessary. 3) Made call number specifically and then it make us easy to identify data and simultaneously call number can do its original action. 4) shelving range of data is made to colleges, years, departments, majors but in same departments, author's name is recommended by Korean alphabetical ordering. Besides, for proper and systematic management and operating of data. It must be necessary to recommend that reading systems of closed shelves type, incoming and outgoing and shelving by fulltime exclusive charged librarian, separate management of items and data are recommended.

• Journal of architectural history
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• v.14 no.3 s.43
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• pp.53-76
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• 2005

Through a field study of the folk houses, 'Closed ㄱㄴ Type' in Goyang-si, Gyonggj-do, focused on the dweller's life by the method of ethnographic interview, observation, and physical survey. L and opposite L type of inner and outer buildings form a closed inner court, and innermost backyard for woman is enclosed by fence. Form and space of the house contains dweller's traditional life. Outer space of a front gate becomes semiprivate space, for thrashing and piling up harvest and raising vegetables and pigs. Confucius principle does not fully dominate dweller's life of ancestral rite at Daecheong floor, and separation of man's and woman's quarter. Superstitious worship activities took place for lord of site and house. In everyday life, Anbang, inner main room, is assigned for parent's quarter instead of woman's quarter, and Geornbang, next room, was for son's family. Anbang has symbolic meaning for a place of deathbed. House contains agricultural activities, crop harvesting, thrashing, putting into storage, hulling rice, and keeping grain near kitchen. At present, rooms are needed more; sheds are made into rooms, rooms are enlarged toward outside, half outside space like Daechong floor becomes interior space by sash screen. And modern facilities of kitchen and bathroom are equipped for convenience. At the end, meaning and generative principle of those forms are discovered.

• Journal of the Korean Geotechnical Society
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• v.21 no.3
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• pp.79-85
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• 2005

An experimental study was carried out to investigate the recycling possibility of waste oyster shells, which induce environmental pollutions by piling up out at the open or the temporary reclamation. The purpose of this study is to develope eco-friendly binder using waste oyster shells, and to reinforce dredged soils fur soft soil improvement. In this paper, a series of laboratory tests including compressive strength tests were performed to evaluate strength characteristics of soils treated by developed binder with different water content of dredged soils, mixing rates of binder, curing days. Based on test results, eco-friendly binders manufactured from waste oyster shells were estimated as good resource materials for soft soil improvements.