• Animal Bioscience
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• v.36 no.7
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• pp.1034-1043
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• 2023

Objective: Two serine protease inhibitors, peptidase inhibitor 3 (PI3) and secretory leukocyte protease inhibitor (SLPI), play important roles in protease inhibition and antimicrobial activity, but their expression, regulation, and function at the maternal-fetal interface in pigs are not fully understood. Therefore, we determined the expression and regulation of PI3 and SLPI in the endometrium throughout the estrous cycle and at the maternal-fetal interface in pigs. Methods: Endometrial tissues during the estrous cycle and pregnancy, conceptus tissues during early pregnancy, and chorioallantoic tissues during mid to late pregnancy were obtained, and the expression of PI3 and SLPI was analyzed. The effects of the steroid hormones estradiol-17β (E2) and progesterone (P4) on the expression of PI3 and SLPI were determined in endometrial explant cultures. Results: PI3 and SLPI were expressed in the endometrium during the estrous cycle and pregnancy, with higher levels during mid to late pregnancy than during the estrous cycle and early pregnancy. Early-stage conceptuses and chorioallantoic tissues during mid to late pregnancy also expressed PI3 and SLPI. PI3 protein and SLPI mRNA were primarily localized to endometrial epithelia. In endometrial explant cultures, the expression of PI3 was induced by increasing doses of P4, and the expression of SLPI was induced by increasing doses of E2 and P4. Conclusion: These results suggest that the PI3 and SLPI expressed in the endometrium and conceptus tissues play an important role in antimicrobial activity for fetal protection against potential pathogens and in blocking protease actions to allow epitheliochorial placenta formation.

• Journal of Korean Neurosurgical Society
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• v.65 no.3
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• pp.449-456
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• 2022

Objective : The aim of this study was to evaluate the clinical outcome of sphenoid wing meningioma with periorbital invasion (PI) after operation. Methods : Sixty one patients with sphenoid wing meningioma were enrolled in this study. Their clinical conditions were monitored after the operation and followed up more than 5 years at the outpatient clinic of a single institution. Clinical and radiologic information of the patients were all recorded including the following parameters : presence of PI, presence of peri-tumor structure invasion, pathologic grade, extents of resection, presence of hyperostosis, exophthalmos index (EI), and surgical complications. We compared the above clinical parameters of the patients with sphenoid wing meningioma in the presence or absence of PI (non-PI), then linked the analyzed data with the clinical outcome of the patients. Results : Of 61 cases, there were 14 PI and 47 non-PI patients. PI group showed a significantly higher score of EI (1.37±0.24 vs. 1.00±0.01, p<0.001), more frequent presence of hyperostosis (85.7% vs. 14.3%, p<0.001), and lower rate of gross total resection (GTR) (35.7% vs. 68.1%, p=0.032). The lower score of pre-operative EI, the absence of both PI and hyperostosis, smaller tumor size, and the performance of GTR were associated with lower recurrence rates in the univariate analysis. However, in the multivariate analysis, the performance of GTR was the only significant factor to determine the recurrence rate (p=0.043). The incidences of surgical complications were not statistically different between the subtotal resection (STR) and GTR groups, but it was strongly associated tumor size (p=0.017). Conclusion : The GTR group showed lower recurrence rate than the STR group without differences in the surgical complications. Therefore, the GTR is strongly recommended to treat sphenoid wing meningioma with PI for the better clinical outcome.

• Proceedings of the KIEE Conference
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• 1999.07d
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• pp.1759-1761
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• 1999

The generation of pretilt in nematic liquid crystal(NLC)and electro-optical(EO) characteristics of photo-aligned twisted nematic (TN)-LCD with oblique p-polarized ultraviolet (UV) light irradiation on the two kinds of the soluble polyimide (PI) surfaces containing trifluoromethyl moieties were investigated. The generated pretilt angle of NLC is about $2.5^{\circ}$ with p-polarized UV light irradiation of $20^{\circ}$ on PI-3 surface at 20 min.; However pretilt angle of about $0.5^{\circ}$ are observed on PI-1 and PI-2 surfaces. The generated pretilt angle of NLC on PI-3 surface may be attributed to the trifluoromethyl moieties attached to the lateral benzene rings. The voltage-transmittance and response time characteristics of photo-aligned TN-LCD with p-polarized UV light irradiation of $20^{\circ}$ on PI-1 surfaceat at 20 min were almost same in comparison with the rubbing-aligned TN-LCD. However, the high threshold voltage and slow response are observed on PI-3 surface. Also, the decay time $\tau_d$ of photo-aligned TN-LCD is attributed to the anchoring energy of NLC.

• Journal of Advanced Navigation Technology
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• v.9 no.1
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• pp.34-40
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• 2005

In this paper we propose a turbojet engine controller of unmanned aircraft based on the Fuzzy-PI algorithm. To prevent any surge or a flame out event during the engine acceleration or deceleration, the PI-type fuzzy controller effectively controls the fuel flow input of the control system. The fuzzy inference rule made by the logarithm function of acceleration error improves the tracking error. Computer simulations applied to the linear model of a turbojet engine show that the proposed method has good tracking performance for the reference acceleration and deceleration commands.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.27 no.4
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• pp.187-194
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• 2015

This paper describes the PI controller design based on a practical transfer function model for centrifugal water chillers. The rotational speed of a compressor and the opening angle of an electronic expansion valve were simultaneously regulated as manipulated variables to maintain temperature reference and to ensure high efficiency of the chiller. The COP according to the change in each variable was investigated by performing some static experiments, and it was reflected in the PI controller design to accomplish the high efficiency control. Especially, the practical transfer function model of the chiller was built based on the dynamic experimental data considering the strong inherent non-linearity and complexity of the chiller system. The validity of the designed PI controller was proven by some experimental results using the test facility and the results were also compared to the conventional evaporating pressure control results.

• Proceedings of the KIEE Conference
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• 2008.04c
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• pp.119-121
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• 2008

This paper is proposed a high Performance speed control of the synchronous reluctance motor through the SV-PWM(Space Vector Pulse Width Modulation) of FAM-PI(Fuzzy Adaptive Mechanism-PI). SV-PWM is controlled using FAM-PI control. SV-PWM can be maximum used maximum do link voltage and is excellent control method due to characteristic to reducing harmonic more than others. Fuzzy control has a advantage which can be robustly controlled. FAM-PI controller is changed fixed gain of PI controller using fuzzy adaptive mechanism(FAM) to match operating condition. The results on a speed controller of IPMSM are presented to show the effectiveness of the proposed gain tuner. And this controller is better than the fixed gains one in terms of robustness, even under great variations of operating conditions and load disturbance.

• The Transactions of the Korean Institute of Power Electronics
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• v.11 no.5
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• pp.426-430
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• 2006

This paper deals with a novel utilization method of the predicted current in the high performance PI current controller with a control time delay. The inevitable error of the predicted current in the linear servo drive using a permanent magnet linear synchronous motor is analyzed and a modified cross-coupling decoupling synchronous frame PI current controller is proposed in order to improve the current control response under both the control time delay and the inevitable current prediction error. Simulation and experimental results show that the proposed current controller has an improved current control performance under both the control time delay and the inevitable current prediction error in the servo drive system.

• Textile Coloration and Finishing
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• v.22 no.2
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• pp.83-87
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• 2010

Crystal structure of coumarin 6 has been solved by X-ray diffraction. The crystals are triclinic, space group P-1, with a=8.823(2) ${\AA}$, b=8.898(2) ${\AA}$, c=11.025(9) ${\AA}$, ${\alpha}$=86.41(3)$^{\circ}$, ${\beta}$=85.39(3)$^{\circ}$, ${\gamma}$=76.23(3)$^{\circ}$, Mr=350.42, V=837.1(3) ${\AA}^3$, Z=2 and R=0.0516. The molecules are packed parallel to each other by weaker ${\pi}{\cdots}{\pi}$ and C-H${\cdots}{\pi}$ interactions. The detailed geometry of C-H${\cdots}{\pi}$ interactions were discussed. The hydrogen bonds and non-traditional C-H${\cdots}O$ interactions join the no-parallel molecules together. All the molecules packed wall-like with the molecular brick.

• Korean Journal of Plant Tissue Culture
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• v.25 no.1
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• pp.45-50
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• 1998

Hypocotyl explants of flowering cabbage were precultured on MS medium without kanamycin and then cocultured with Agrobacterium tumefaciens LBA4404;;pGA875 harboring insect resistantce proteinase inhibitor II(PI-II) gene in MS liquid medium adjusted pH 5.5 for 72hr. These explants were transferred to MS medium containing 20 mg/L kanamycin, 500 mg/L carbenicillin, and 1 mg/L BA. The explants were subsequently subcultured every 2 weeks. After 4 weeks of subculture, kanamycin-resistant shoots were obtained from selection medium. Leaves of putative transformants survived on MS selection medium containing 30 mg/L kanamycin. Incoporation of the PI-II gene into flowering cabbage was confirmed by PCR analysis of genomic DNA. Southern blot analysis showed that ECL-labeled probe for PI-II gene was hybridized to the expected amplified genomic DNA fragment of about 500 by from transgenic flowering cabbage.

• Proceedings of the KIEE Conference
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• 2007.04c
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• pp.91-93
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• 2007

This paper presents multi-PI controller of IPMSM drive using fuzzy and neural-network. In general, PI controller in computer numerically controlled machine process fixed gain. To increase the robustness, fred gain PI controller, Multi-PI controller proposes a new method based fuzzy and neural-network. Multi-PI controller is developed to minimize overshoot and settling time following sudden parameter changes such as speed, load torque, inertia, rotor resistance and self inductance. The results on a speed controller of IPMSM are presented to show the effectiveness of the proposed gain tuner. And this controller is better than the fixed gains one in terms of robustness, even under great variations of operating conditions and load disturbance.