• 생약학회지
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• 제26권1호
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• pp.1-7
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• 1995

The bark of Ulmus parvifolia Jacq. (Ulmaceae) has been used for the treatment of gonorhea, edema, scabies and eczema marginatum. Previous investigations conducted with the heartwood and leaves have demonstrated it to contain sesquiterpenes as well as fat acids from the heartwood and flavonol glycosides from leaves. However, no phytochemical work has been done on the bark parts of this plant. Investigation of the phytochemical constituents in the barks of U. parvifolia has resulted in the isolation of sterols, sterol glucoside and a catechin glycoside, $(+)-catechin\;7-O-{\alpha}-{_L}-rhamnopyranoside$, all of which were isolated for the first time from this plant. Sterols were consisted of the three components, ${\beta}-sitosterol$, stigmasterol and campesterol in a ratio of 92.1:4.1:3.8, and sterol glucoside was identified as ${\beta}-sitosterol\;3-O-{\beta}-{_D}-glucoside$. The structure of the catechin $7-O-{\alpha}-{_L}-rhamnoside$ was established primarily by analysis of $^1H-and$ COSY-45 NMR, HMQC and HMBC and EI mass spectra of the heptaacetate. Especially, HMBC spectrum provides effective way for the determination of the point of attachment of the rhamnosyl group to catechin moiety.

• Journal of Electrochemical Science and Technology
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• 제9권3호
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• pp.238-249
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• 2018

The impact of methanol extract of Chaenomeles sinensis (C. sinensis) leaves on acid corrosion of low carbon steel was assessed by gravimetric and electrochemical methods. Phytochemical characterization by total phenolic content (TPC), and total flavonoids content (TFC) of the extract was performed. The TPC and TFC concentrations were identified as 193.50 and 40.55 mg/g. Efficiency increased remarkably in the presence of inhibitor and found as concentration dependent. A maximum inhibition efficiency of 93.19% was achieved using 2000 ppm of the C. sinensis inhibitor. Impedance and surface morphology analysis by SEM and AFM revealed that the anticorrosive activity results from the protective film of phytochemical components of C. sinensis extract adsorbed on the metal surface.

• 생약학회지
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• 제26권2호
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• pp.130-138
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• 1995

Phytochemical study on the aerial parts of Solanum lyratum (Solanaceae) was carried out. On the basis of phytochemical and spectroscopic evidences, compound I was identified as mixtures of hexadecanoic acid methyl ester, 2,6,10,15-tetramethyl heptadecane, tricosane, tetracosane, pentacosane, docosanoic acid methyl ester, docosane, tricosanoic acid methyl ester, 8-hexyl pentadecane, tetracosanoic acid methyl ester, pentatriacontane, hexatriacontane, eicosane, hexacosane, hentriacontane and stigmasta-5,23-dien $3-{\beta}-ol$, and compound II, III, IV and V were identified as hexacosanoic acid methyl ester, ${\beta}-sitosterol-{\beta}-{_D}-glucoside$, $3-O-{\alpha}-{_L}-rhamnopyranosyl-(1->2)-{\beta}-{_D}-glucuronopyranosyl$ diosgenin and $3-O-{\alpha}-{_L}-rhamnopyranosyl-(1->6)-{\beta}-{_D}-glucopyranosyl$ quercetin (rutin), respectively. Rutin was identified as one of the active principles having antioxidative effect from S. lyratum.

• 식품보건융합연구
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• 제6권3호
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• pp.5-21
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• 2020

Bungkang (Syzygium polyanthum) is a medium to tall plant which produces medicinal root-bark, the plant is normally found along inland river bank and produces small white flowers and fruits. Essential oils are among the most interesting components of the plant extracts consisting mostly of monoterpenoid or sesquiterpenoids. They are used as therapeutic agents in ethno, conventional, and complementary alternative medicines. Investigation and evaluation of the essential oil of Syzygium polyanthum as well as the antibacterial, antioxidant and antifungal activity was ascertained. The experiment was performed. 100 chemical constituents were obtained and two pure compound was isolated as Eugenol (1) and Farnesol (2). Significant growth inhibition of Staphylococcus aureus, (ATCCⓒ25923) Klebsiellia pneumonia (ATCCⓒ19155), Salmonella typhi (ATCCⓒ14028) and Escherichia coli (ATCC©25922) and the fungal strains Aspergillus flavin, Aspergillus niger, Candida, tropicalis, and Fusarium oxysporium was observed from the essential oil at concentration of 500 ㎍/mL. Antioxidant potential was observed to be strong of 18.42 ㎍/mL when compared to the control of 15.23 ㎍/mL. The result indicated that the oil obtained from root-bark of Syzygium polyanthum can be considered as an agent for antioxidant, antibacterial and antifungal in pharmaceutical food and cosmetic industries trails.

• 한국자원식물학회지
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• 제21권6호
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• pp.420-426
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• 2008

Phytochemical investigation of the sesame dregs of Sesamum indicum was conducted by open column and prep-HPLC chromatography. Two phytosterols (1 and 2) and two lignans (3 and 4) were isolated from the MeOH extracts of sesame dregs, and identified as ${\beta}$-sitosterol (1), daucosterol (2), sesamin (3), and sesamolin (4) by spectral analysis. Although these compounds were already isolated from sesame, it is important that they were still main phytochemical components in the sesame dregs.

• Mass Spectrometry Letters
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• 제14권3호
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• pp.79-90
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• 2023

Natural goods, especially therapeutic plants, are abundant in the World. Because they have the ability to provide all humanity with countless advantages as a source of medicines, medicinal plants are presently receiving more attention than ever. These plants' therapeutic efficacy is based on bioactive phytochemical components that have clear physiological effects on the human body. The drying process is crucial for the preparation of plant materials prior to extraction since freshly harvested plant materials include active enzymes that create active components, intermediates, and metabolic processes. Many of the phytoconstituents may be extracted using the semi-polar solvent methanol. The goal of the current work is to use the GC-MS gas chromatography- mass spectrometry technology to identify the phytochemicals and review their biological activity. In methanol leaf extract, 5 phytocompounds were found in Ricinus communis, 5 phytocompounds in Pongamia pinnata, 12 phytocompounds in Datura metal, 7 phytocompounds in Azadirachta indica, 11 phytocompounds in Acalypha indica.

• 한국작물학회지
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• 제68권2호
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• pp.59-68
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• 2023

본 연구는 국립식량과학원에서 육성한 단옥수수 자식계통의 phytochemical 함량과 항산화 활성을 평가하여 고기능성 단옥수수 품종 육성을 위한 기초 자료로 이용하고자 수행하였다. 1. Carotenoid 함량이 가장 높은 계통은 KSE34 (1239.3±6.4 mg 100 g^-1), flavonoid 함량이 가장 높은 계통은 KSE6(68.6±9.6 mg CE 100 g^-1)으로 나타나 각 계통마다 화합물의 함량이 다양하였다. Phenolic compound 함량은 대부분의 단옥수수 자식계통에서 풍부하게 나타났으며, KSE8과 KSE25가 가장 높은 함량을 가진 계통이었다. 2. DPPH와 ABTS 라디칼 소거능으로 평가한 국내 단옥수수 자식계통의 항산화 활성 중 DPPH 활성은 계통 간에 다양하였으나, ABTS 활성은 차이가 적게 나타났다. KSE30과 KSE6이 각각 108.4±9.6 mg TE 100 g^-1, 104.2±12.8 mg TE 100 g^-1로 가장 좋은 DPPH 활성을 보인 계통이었으며 KSE47, KSE4, KSE21은 낮은 활성을 보였다. 3. 계층 군집 분석과 주성분 분석을 사용하여 단옥수수 자식계통의 농업적 특성을 비교하고 분류하였다. Carotenoid, polyphenol, flavonoid 함량이 높고 항산화 활성이 우수한 4개 계통(KSE6, KSE30, KSE34, KSE40)이 선발되었고, 향후 조합 능력 평가를 거쳐 고기능성 단옥수수 품종 개발에 활용할 것이다.

• 한국작물학회지
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• 제55권3호
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• pp.200-206
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• 2010

Banaba, Lagerstroemia speciosa (L.) Pers. (Lythraceae) is a tree that grows in the tropic islands of the Pacific. This plants are used for medical purposes in the world. The components of L. speciosa were analyzed for the contents according to growing stages at leaves. The distributions of the corosolic acid ($2{\alpha}$, $3{\beta}$-dihydroxyurs-12-en-28-oic acid), phytol, campestrol, and vitamin E were rich among samples in this study. These were contained much fatty acids. The mean content of palmitic acid was from 2.4% across all growing stages, varying from 2.15% for young leaves with the lowest content and 2.86% for fallen leaves with the highest content. Oleic acid, linoleic acid, and linolenic acid were contained nearly mean 2.0% in all leaves of banaba. Our results have shown that the phytochemical profile of young L. speciosa leaves differs quite radically from that of old L. speciosa leaves. In addition, these subdividing results according to plant growth should allow future researches to conduct targeted experimental studies and use of particular medical components of interest, examining chemical variation on the inter-developmental levels.

• Biomolecules & Therapeutics
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• 제24권6호
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• pp.630-637
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• 2016

The chemical components and biological activity of Camellia mistletoe, Korthalsella japonica (Loranthaceae) are relatively unknown compared to other mistletoe species. Therefore, we investigated the phytochemical properties and biological activity of this parasitic plant to provide essential preliminary scientific evidence to support and encourage its further pharmaceutical research and development. The major plant components were chromatographically isolated using high-performance liquid chromatography and their structures were elucidated using tandem mass spectrometry and nuclear magnetic resonance anlysis. Furthermore, the anti-inflammatory activity of the 70% ethanol extract of K. japonica (KJ) and its isolated components was evaluated using a nitric oxide (NO) assay and western blot analysis for inducible NO synthase (iNOS) and cyclooxygenase (COX)-2. Three flavone di-C-glycosides, lucenin-2, vicenin-2, and stellarin-2 were identified as major components of KJ, for the first time. KJ significantly inhibited NO production and reduced iNOS and COX-2 expression in lipopolysaccharide-stimulated RAW 264.7 cells at $100{\mu}g/mL$ while similar activity were observed with isolated flavone C-glycosides. In conclusion, KJ has a simple secondary metabolite profiles including flavone di-C-glycosides as major components and has a strong potential for further research and development as a source of therapeutic anti-inflammatory agents.

• Nutritional Sciences
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• 제6권3호
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• pp.160-166
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• 2003

To examine the evidence that wheat bran is protective against breast cancer development and that its main mechanism of action is by modulating estrogen metabolism. This review explores the role of different experimental factors on the anticancer effects of wheat bran and the relationship of changes to estrogen metabolism by wheat bran on breast cancer risk The timing of the experimental diets in relation to carcinogen administration, the length of feeding of the experimental diets, and the level of dietary fat had an impact on the effectiveness of different doses of wheat bran in reducing breast carcinogenesis. Wheat bran supplementation resulted in significant reductions in human plasma estrogen levels but not in that of animals tested. The change in excretory metabolism of estrogen by wheat bran feeding in animals was not related to any of the tumor indices measured. The protective effect of wheat bran in breast carcinogenesis is greatest at the promotional phase and when supplemented in a high fat diet. Doses of wheat bran in the 9-12% range in diet have been consistently protective. The inconsistency observed with higher doses of wheat bran may be dependent on the animal model used. Although wheat bran's inhibitory effects on tumor growth may involve changes to estrogen metabolism, the fiber and phytochemical components of wheat bran may also act through estrogen-independent mechanisms. For a better understanding of the effect of wheat bran on breast carcinogenesis, studies comparing the effects of different wheat bran components both alone and in combination need to be performed.