• Title/Summary/Keyword: physiological factors

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Physiological Factors and Regulatory Genes Involved in Streptomycetes Antibiotic Biosynthesis (방성균의 항생제 생합성에 관여하는 생리적 인자 및 조절 유전자의 특성)

  • 김응수
    • The Microorganisms and Industry
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    • v.27 no.2
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    • pp.13-22
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    • 2001
  • 방선균은 필라멘트 형태를 띤 대표적인 그램 양성 세균으로서, 다양한 자연환경에 존재하는 대표적인 토양 미생물이다. 방성균이 항생제를 포함한 다양한 구조의 많은 유용 생리활성물질을 생성하며, 이들의 생합성 시기가 세포의 배양상태 및 생장속도와관련이 있다는것은 이미 주지의 사살이다. 비록 방선균은 액체 배양 시에는 정체기((stationary phase)나 낮은 생장속도하에서만 항생제를 생성하며, 고체 배양 시에는 aerial mycelia 로 형태적분화(morphological differentiation)를 시작함과 동시에 생합성을 시작한다고 알려져 있으나, 각 방선균 및 항생제의 종류에 따른 특징적인 조절 기작은 매우 다양한 것으로 알려져 있다. 따라서 특징적인 조절 기작은 매우 다양한것으로 알려져 있다. 따라서 본 총성레서는 항생제 생합성이 조절되는 기작을 지금까지 밝혀진 방선균의 여러 생리적 인자 및 생합성 조절 유전자를 중심으로 정리해 보고자 한다. 항생제 생합성에 관하여 다양한 생리적 인자와 조절 유전자의 특정 및 이들의 상호관계에 대한 종합적인 이해는, 방선균 유래 항생제 조절 기작의 체계적인 규명뿐만 아니라, 방선균을 이용한 유용 생리활성물질의 생산성 향상에도 응용될수 있다는 점에서 매우 중요하다.

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Environmental factors affecting seasonal destribution of heterotrophic bacteria in Kum river estuarine sediments (금강 하구 퇴적토에서의 종속영양 세균의 분포에 미치는 환경요인과 계절적 우점속에 관하여)

  • 이건형
    • Korean Journal of Microbiology
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    • v.25 no.2
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    • pp.137-143
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    • 1987
  • Dominant genera of heterotrophic bacteria were investigated seasonally in Kum River estuarine sediments. Numerical taxonomy on the isolated heterotrophic bacteria were carried out according to their morphological, physiological, nutritional and biochemical characters. Heterotrophic bacteria in the depths of 0 to 10 cm of sampled sediments were almost facultative anaerobes, and 77.9% to 86.9% of them were Gram negative rods. Kominant genera among the isolates were Pseudomonas, Flavobacterium, Micrococcus, Cnterobacteria and Vibrio during sampling periods. According to their character analyses by similarity index(S), the isolates were clustered in fourteen groups at clay type sediments (Site 1) and four groups at sand type sediments (Site 2).

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A Survey on the Current State and the Characteristics of Scoliosis in College Students

  • Jung, Hwa Shik
    • Journal of the Ergonomics Society of Korea
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    • v.18 no.3
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    • pp.13-26
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    • 1999
  • 126 male and 95 female Korean college students were examined for Scoliosis by using Moire type body observation apparatus. Scoliotic hump measuring instrument, and spinal cord side curvature condition measuring instrument. The prevalence rate of Scoliosis along with identifying its possible causal factors and characteristics were investigated. The results revealed that 5.56% of male and 8.42% of female students(male to female ratio 1:1.47) were suspected as having Scoliosis. There was a significant correlation between the students who have symptoms of Scoliosis and their physiological measurements(e.g., lower breathing capacity of the lungs). There were also close relationships between the suspected cases and their habits(e.g., poor sitting and sleeping posture). It is concluded that the Scoliosis in Korean college students should not be ignored.

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Nonpharmacological Treatment of Insomnia (불면증의 비약물학적 치료)

  • Yoon, In-Young
    • Sleep Medicine and Psychophysiology
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    • v.7 no.1
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    • pp.5-9
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    • 2000
  • Several nonpharmacological treatment methods of insomnia and their effects were reviewed. A long-term use of most hypnotics may produce tolerance, dependence, cognitive and psychomotor impairments at daytime, shallow sleep, and rebound insomnia on drug withdrawal. To reduce hypnotic abuse, nonpharmacological strategies have been developed to correct disordered behavioral and cognitive factors. These treatments aim at modifying maladaptive sleep habits, lowering physiological and cognitive arousal levels, and correcting dysfuctional beliefs and attitudes about sleep. These non-pharmacological or cognitive behavior treatments include stimulus control, sleep restriction, relaxation training, sleep hygiene education, cognitive therapy, and light therapy. Among them the stimulus control therapy has been demonstrated most effective as a single treatment or in combination with other treatments. Through nonpharmacological treatments, sleep latency was most significantly reduced and wake time after sleep onset was also reduced. About 50% of insomniacs reported clinical improvements in terms of nearly normalized sleep latency, awakening time, sleep efficiency, and reduction of hypnotic use. Compared to the hypnotic therapy, nonpharmacological treatments are more cost-effective and more readily accepted by patients, and their effects last longer.

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Update on the Extracorporeal Life Support

  • Huh, Jin-Won
    • Tuberculosis and Respiratory Diseases
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    • v.78 no.3
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    • pp.149-155
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    • 2015
  • Extracorporeal life support (ECLS) is a type of cardiopulmonary bypass. It is an artificial means of supplying oxygen and removing $CO_2$ on behalf of damaged lungs while patients are recovering from underlying diseases. Recently, the use of ECLS is rapidly increasing as this machine becomes smaller, less invasive and easier to use. In addition, the improvement of clinicians' technique and outcome is increasing their application to patients with acute respiratory distress. In this regard, the purpose of this review is to introduce the physiological principles, risk factors, and advantages of ECLS, clinical rationale for using ECLS, ventilatory strategy during ECLS, which are still causing different opinions, the weaning from ECLS, and the use of anticoagulant.

Study on the Yo Bae Byoung Hoo of the Je Bung Won Hu Ron (제병원후론ㆍ요배병제후에 대한 연구)

  • An Min Sik;Jeong Heon Young
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.3
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    • pp.624-628
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    • 2003
  • JebyeongwonhuronㆍYobaebyeonjehu is well organized and detailed is stated of classification and cause, mechanism of lumbago. That is divided into nine classes according to cause and symptoms of lumbago and described those respectively. Although there is some different, classification of lumbago after ages is based on this method in the main. The outbreak mechanism of lumbago can be stated that wicked germ invade into the body in condition that spirit and energy, especially the kidney energy is poor through various reason. That is stressed on interior factors. In the relation to organs, it is inferred that outbreak of lumbago have connection with the kidney deeply.

Correlation Study between Brain Atrophy and Risk Factors for Cerebrovascular Disease (노화에 관련된 뇌위축과 뇌혈관 질환의 위험인자와의 상관관계 연구)

  • Ko, Heung;Moon, Jo Ho;Kim, Ki Tae;Shin, Seon Mi
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.28 no.2
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    • pp.200-205
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    • 2014
  • Based on the way we have created to measure the brain atrophy of pons, frontal lobe, sylvian fissure, ventricle, cerebellum, we analyzed the correlation with age. We confirmed whether the brain atrophy due to hypertension, diabetes, hyperlipidemia, drinking, smoking is increasing. Brain deficiency(髓海不足), Brain dissatisfied(腦爲之不滿), Brain Consume(腦髓消烁) listed in Donguibogam(東醫寶鑑) have to be diagnosed with brain atrophy induced by developmental disorders, diseases, aging. Sylvian fissure is well reflected brain atrophy progressed by aging. And brain atrophy increased in hypertension, diabetes, hyperlipidemia, drinking, smoking is well reflected at Sylvian fissure.

Ergonomic Evaluation of Convenient Appliances for Elderly Driver's Ingress/Egress (고령자 승/하강 편의장치에 대한 효과 검증 및 개선방향 연구)

  • Park, Woo-Chul;Yang, Young-Seon;Jang, Chee-Hwan;An, Dae-Jin;Lim, Sung-Hyun
    • Journal of the Ergonomics Society of Korea
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    • v.29 no.1
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    • pp.61-66
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    • 2010
  • The objective of this paper is to study the usability of the ingress/egress of elderly people, and analyze the physiological workload electromyography (EMG). We investigated the factors of discomfort while the elderly people are using the ingress/egress. Experiments were performed using a seating buck with 22 elderly participants (over 65 years old). The results showed that different muscles are activated during ingress and egress. A system called "easy access" was found which helps to access easily when a driver gets into a car. The current easy access was compared a newly proposed one. It was found that elderly people use less muscle during in/egress in the new easy access system.

An Application of Evacuation Model for Rail Passenger Car (철도차량에 대한 피난모델 적용)

  • Kim, Jong-Hoon;Kim, Woon-Hyung;Lee, Duck-Hee;Jung, Woo-Sung
    • Proceedings of the KSR Conference
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    • 2007.11a
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    • pp.123-128
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    • 2007
  • To predict the fire and smoke hazards of rail car with a evacuation model is essential for achieving life safety of all passengers in the event of fire. Currently, more than 30 different evacuation models are available and expected increasing demand in high population density areas as a metro train station. This paper includes brief history of evacuation models and review some key factors of design egress scenario, these are pre-movement time, egress route, location of fire, overturned carriage, and configuration of rail car. Applying the egress model for rail passenger car, users need to confirm the model's ability of physiological, psychological responses effecting to pre-movement time of individual or crowd unit, representation of complexity of carriage layout, and evaluation of effects of smoke.

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An Investigation of Undescribed Black Root Rot Disease of Soybean Caused by Cylindrocladium(Calonectria) crotalariae in Korea (콩의 미기녹(未記錄) 병(病)인 Cylindrocladium(Calonectria) crotalaria에 의한 흑색(黑色) 뿌리썩음병)

  • Sung, Jae-Mo
    • The Korean Journal of Mycology
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    • v.8 no.1
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    • pp.53-57
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    • 1980
  • An undescribed black root rot of soybean, caused by Cylindrocladium crotalariae, was observed in Suweon area. The diseased plants showed yellowing at the top and dry rot at the root. Lesions of roots and stems in the soil were red to brown and main roots were cracked. Although not observed the disease in the field, leaves of inoculated test plants in the greenhouse exhibited circular, brown lesion surrounded by chloratic halos. The fungus was recovered in culture from the infected stem and root, and the perithecia of Calonectria crotalariae were demonstrated to be present as well as the cylindrocladium state. The fungus was pathogenic to the root, stem, petioles and leaves of soybean. The probable source of primary inoculum was microsclerotia formed in infected soybean root and stem from the previous season's soybean debris. Black root rot by this fungus was considered to be one of detrimental factors to the maximum yield of soybean. From the morphological and physiological characteristics and pathogenic behaviors, this fungus was identified as Cylindrocladium(Calonectria) crotalariae.

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