• Anxiety and mood
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• v.11 no.2
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• pp.143-148
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• 2015

Objective : This study examined benzodiazepine prescription patterns of outpatients visiting the psychiatry department in a single general hospital in Korea. Methods : A retrospective descriptive analysis of benzodiazepine prescriptions was performed on a database from 2014 in a general hospital in Korea. We analyzed the following factors of adult outpatients: demographic factors such as sex and age, amount of benzodiazepine prescribed, treatment duration, and diagnosis based on the ICD-10. Results : In 2014, benzodiazepines were prescribed to 46.4% of the outpatients. Percentage of benzodiazepine prescription increased with age and was highest in the age group 40-59 years. Prescription was more prevalent in women and the prescription percentage increased by treatment duration. Patients with the F4 diagnosis (neurotic, stress-related and somatoform disorders) were the most highly prescribed group. For all diagnosis groups, prescription was more prevalent in females or similar for both sexes except for patients with F5 diagnosis (behavioral syndromes associated with physiological disturbances and physical factors), with males being more predominant. Conclusion : Despite the concern regarding the rate of benzodiazepine prescription and administration to geriatric patients, long-term prescription and usage among older patients is still prevalent.

• Journal of the Ergonomics Society of Korea
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• v.29 no.2
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• pp.211-216
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• 2010

Fire service personnel and ambulance paramedics suffer musculoskeletal disorders as they lift and carry patients while performing Emergency Medical Services (EMS). The objective of the current study was performed to examine the association between working environment and musculoskeletal disorders of 119 paramedics and to analysis the EMS activities for them through basic survey (including task characteristics, risk factors, symptoms and illnesses). Observational job analysis of EMS activities indicated the squatting posture during first-aid performed on floor and the abrupt use of force during carrying heavy load including stretcher with patients on as hazard factors, and excessive low back twisting and bending during stairway transfer was observed. In addition, work-physiological assessment revealed various but rather high lumbar muscle usage rate among the study subjects, being 14.6~32.8% compared with Maximum Voluntary Contraction (MVC) during patients transfer work. Resting heart rate showed 65/min, on the other hand, heart rate on mobilization indicated maximum 124~156/min. Therefore, the results of analysis to the EMS activities, rescuer activities and medical tasks were accompanied with high possibility of accident and musculoskeletal disorders. Also, EMS activities indicated high muscle fatigue and energy consumption, and accumulated muscle fatigue with during continued work.

• Journal of The Korean Dental Society of Anesthesiology
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• v.10 no.1
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• pp.27-33
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• 2010

The gag reflex is a physiologic reaction which safeguards the airway from foreign bodies. But, an exaggerated gag reflex can be a severe limitation to a patient's ability to accept dental care and for a clinician's ability to provide it. The overactive gag reflex can be due to psychological factors or physiological factors, or both. Psychological factors can include fear of loss of control and past traumatic experiences. A 58-year-old man, scheduled for extraction of left upper second molar, left lower second and third molar and implantation of left upper second molar, and left lower second molar had no specific underlying medical problems. He had exaggerated gag reflex. Dental treatment was successfully performed using intravenous sedation. Intravenous sedation with midazolam and propofol was a useful management technique for reflex control during dental treatment extended to the posterior regions in the oral cavity.

• Journal of Families and Better Life
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• v.9 no.2
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• pp.171-190
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• 1991

This study focused on time use and the influencing factors of employed wives. Its aims are specified as follows.:1) to figure out the tendency of time use spent on a holiday and weekday by employed wives ; (2) to find out factors influencing the amount of time in each domain spent on each day. The samples were composed for 396 employed wives living in Seoul and Kwangju city who had the eldest child less than 18years old. were sampled based on their work kind, work status, and residential quarter. The results are as follows; 1) Employed wives spend 423 minutes a weekday, and 513 minutes a holiday on the sleep and 522 minutes(weekday ), 618 minutes (holiday) on the total Physiological time 599 minutes (weekday), 72 minutes(holiday) were devoted to the employed time. compared to 214 minutes. 395 minutes for the housework Finally 103 minutes and 349 minutes were assigned to leisure time. Compared with the research results in Japan and the United States, this shows large difference. Korean wives; work time is excessively too long while the time for leisure and psysiological time is too short, which means the life style of Korean wives ti too simple and monotonous. 2) Social demographic variables(such as work status, education, income, wive's relative income rate, family type. family number, the younger child's age, and etc. )and variables connected with employment (such as employed work time and employment motivation) significantly differentiate the time use. A wive with higher education, employment status, and income level, spends more time for the psysiological , leisure time, and manegerial housework time, while spending less time for work and physical housework.

• Journal of Embryo Transfer
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• v.27 no.4
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• pp.211-221
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• 2012

The process of embryo implantation requires physical contact and physiological communication between the conceptus trophectoderm and the maternal uterine endometrium. During the peri-implantation period in pigs, the conceptus undergoes significant morphological changes and secretes estrogens, the signal for maternal recognition of pregnancy. Estrogens secreted from the conceptus act on uterine epithelia to redirect $PGF_2{\alpha}$, luteolysin, secretion from the uterine vasculature to the uterine lumen to prevent luteolysis as well as to induce expression of endometrial genes that support implantation and conceptus development. In addition, conceptuses secrete cytokines, interferons, growth factors, and proteases, and in response to these signals, the uterine endometrium produces hormones, protease inhibitors, growth factors, transport proteins, adhesion molecules, lipid molecules, and calcium regulatory molecules. Coordinated interactions of these factors derived from the conceptus and the uterus play important roles in the process of implantation in pigs. To better understand mechanism of implantation process in pigs, this review provides information on signaling molecules at the conceptus-uterine interface during early pregnancy, including recently reported data reported.

• Biotechnology and Bioprocess Engineering:BBE
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• v.7 no.1
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• pp.10-15
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• 2002

Environmental and medium factors were investigated as basic data for optimizing DHA production when using Thraustochytrium aureum. To study the effect of environmental conditions, the rotation speed and culture temperature were changed. Plus the trend of the growth characteristics, lipid content in the biomass, and DHA content in lipids were evaluated according to various initial glucose concentrations. The biomass, lipid, and DHA analyses showed that the physiological characteristics of T. aureum were closely related with the environmental and medium conditions, as in the case of other marine microorganisms. For example, a low rotation speed of 50 rpm lowered the cell growth rate as well as the DHA content in the lipids. A low temperature had a negative effect on the cell growth, yet a positive effect on the lipid content in the biomass. Different initial glucose concentrations had no effect on the lipid content in the biomass or DHA content in the lipids, yet did affect the cell growth. Accordingly, these results show that environmental and medium factors must be synthetically considered in order to optimize DHA production when using T. aureum.

• Bulletin of the Korean Institute for Industrial Safety
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• v.3 no.1
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• pp.11-17
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• 2003

In recent years, work-related musculoskeletal disorders (WMSDs) are one of major issues in occupational safety and health in Korea, since the number of injured workers has rapidly increased and the related regulation was amended to improve the work conditions. Main risk factors of WMSDs in Korean industries include manual handling of heavy weight loads, awkward postures, repetitive tasks, prolonged static muscle contraction, and so on. in this article, some ergonomics case studies for identifying the risk factors of WMSDs and far their prevention were introduced. They include a biomechanical analysis for the heavy-weight handling task in a machine-repair shop, physiological evaluation of backpack-carrying tasks in a beverage delivery job, and a set of psychophysical studies to evaluate static-postural load. These studies showed that there are several different ergonomic approaches to identifying and evaluating risk factors of WMSDs and to eliminating them or reducing their levels, and that it is important to select proper methods and apply them in improving the work conditions according to the characteristics of the task. In addition, it needs to develop practical and effective ergonomic tools to prevent WMSDs and to provide these tools to the safety managers in the field so that they can improve the tasks by themselves.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.4
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• pp.849-855
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• 2007

Atopic dermatitis is an allergic inflammatory skin disease caused by aberrant and overreactive immune responses including overactivation of $T_H2$ immune responses, high levels of IgE as well as proinflammatory cytokines and chemokines. We examined whether BHOSB, a traditional herbal medicine, has modulatory effects on various immunological factors related to pathogenesis of atopic dermatitis in ONCB treated NC/Nga mice. Oral administration of BHOSB at the concentration of 10.8 mg/mouse/day significantly inhibited the production of IgE compared with control, and the levels of IgG2a and IgG2b, but not IgG1, were also significantly reduced. Production of IL-6 and TNF-a was greatly decreased. The results from flowcytometry of peripheral blood mononuclear cells indicated that the percentages of C03+C069+ cells and C04+ were significantly decreased by BHOSB. Theses results suggested that BHOSB has suppressive effects on aberrant and overreactive immunological activities in ONCB-induced dermatitis mice of NC/Nga.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2005.05a
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• pp.93-97
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• 2005

People can't be free from the panic of flood, war and terrorism which could be fatal for people's life and property in modern society. It is the most important thing that provide food and residence for suffers in disaster areas. When disaster occurred, the emergency public facilities would be the first place that the people stay. However, these also could be destroyed by disaster. In that case, emergency tents or containers could be the major residence for disaster suffers. Because the only concern for planning temporary residence is the matter of supply and efficiency, it is no longer useful after the disaster end. Therefore, temporary residence as well as general residence should be on the basis of social and cultural factors as well as basic and physiological factors. It is very crucial to study the model of temporary residence. It could be the fundamental and necessary for the human being in order to prepare the natural disaster and grand scale accident. The main purpose for this study is examining the temporary residence that satisfy the fundamental, social and cultural factors for disaster sufferers.

• Molecules and Cells
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• v.39 no.7
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• pp.524-529
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• 2016

Controlling the production of diverse cell/tissue types is essential for the development of multicellular organisms such as animals and plants. The Arabidopsis thaliana root, which contains distinct cells/tissues along longitudinal and radial axes, has served as an elegant model to investigate how genetic programs and environmental signals interact to produce different cell/tissue types. In the root, a series of asymmetric cell divisions (ACDs) give rise to three ground tissue layers at maturity (endodermis, middle cortex, and cortex). Because the middle cortex is formed by a periclinal (parallel to the axis) ACD of the endodermis around 7 to 14 days post-germination, middle cortex formation is used as a parameter to assess maturation of the root ground tissue. Molecular, genetic, and physiological studies have revealed that the control of the timing and extent of middle cortex formation during root maturation relies on the interaction of plant hormones and transcription factors. In particular, abscisic acid and gibberellin act synergistically to regulate the timing and extent of middle cortex formation, unlike their typical antagonism. The SHORT-ROOT, SCARECROW, SCARECROW-LIKE 3, and DELLA transcription factors, all of which belong to the plant-specific GRAS family, play key roles in the regulation of middle cortex formation. Recently, two additional transcription factors, SEUSS and GA- AND ABA-RESPONSIVE ZINC FINGER, have also been characterized during ground tissue maturation. In this review, we provide a detailed account of the regulatory networks that control the timing and extent of middle cortex formation during post-embryonic root development.