• Women's Health Nursing
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• v.26 no.1
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• pp.49-60
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• 2020

Purpose: Infertile women experience various physical, psychological, and relational problems that affect their infertility-related quality of life (QoL). This study investigated infertile women's infertility-related QoL with the goal of identifying how it is influenced by fatigue, depression, and marital intimacy. Methods: A sample of 140 infertile women was surveyed in a cross-sectional study. Data were collected from February to April 2018 using self-report structured questionnaires at three infertility clinics located in Jeonju, Korea. Data were analyzed using the independent t-test, analysis of variance, Pearson correlation coefficients, and stepwise multiple regression analysis in SPSS for Windows version 25.0. The subjects agreed to complete a face-to-face interview, including administration of the Fatigue Severity Scale, Depression Anxiety Stress Scale-21, Marital Intimacy Scale, and the Fertility Quality of Life tool. Results: The mean age of the participants was 35.6±4.3 years. Infertility-related QoL was negatively correlated with fatigue (r=-.42, p<.001) and depression (r=-.56, p<.001), and positively correlated with marital intimacy (r=.30, p<.001). Multiple regression analysis showed that depression (β=-0.44, p<.001), fatigue (β=-0.27, p<.001), and husband's attitude (β=-0.19, p=.007) had significant effects on the QoL of infertile women, accounting for 40.5% of the variance in infertility-related QoL. Conclusion: The study provides insights into how infertile women's infertility-related QoL was influenced by depression, fatigue, and their husbands' attitudes regarding infertility treatment. To improve infertile women's infertility-related QoL, healthcare providers should consider developing strategies to decrease depression and fatigue in infertile women and to address their husbands' attitudes.

• Journal of Life Science
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• v.25 no.11
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• pp.1324-1330
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• 2015

The present study was performed to analyze and review the physical and immune responses to overtraining syndrome in humans. Overreaching refers to the initial phage of overtraining syndrome and has been known as a physical fatigue which is mainly from metabolic imbalance. It has been known that overtraining also results in a loss of adaptability which may lead to an attenuation of exercise performance, sleeping disorder, central fatigue, neurohormonal changes, difficulty recovery to physical stress, and immunological changes. Additionally, overtraining syndrome is characterized by persistent fatigue, poor performance in sport due to the prolonged and strenuous physical training. Also, previous studies reported that endurance athletes experienced a high incidence of URTI during intense training and the post training. And also, high-performance athletes reported that suppression of cell mediated and anti-body mediated immune function. NK cell numbers were also reduced in the period of overtraining syndrome. Major components of prevention and treatment for the overtraining syndrome are screening, education, and detraining. Furthermore, the combination of these prevention and treatment strategies will be much helpful. Therefore, the current review will be helpful for athletes and individuals who are at the risk of overtraining syndrome.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.161-169
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• 2020

The factors influencing the quality of life of physical and mental health in middle-aged women were examined. Secondary analysis was conducted using the data from the 2016 Korea Health Panel data. Method: The Korea Health Panel data 2016 were collected from February to August 2016 by the Korea Institute for Health and Social Affairs and the National Health Insurance Corporation and included 2,437 people who responded to the questionire. Using the SPSS Win program, the data were analyzed using a t-test, ANOVA, Pearson correlation coefficient, and multiple regression analysis. For physical health, the factors affecting the HRQoL were hearing problems, visual problems, eating problems, and physical activity. For mental health, the factors affecting HRQoL were suicidal impulse, stress subjective health. Conclusion: The results indicated that to improve the HRQoL of middle-aged women, a psychological nursing intervention program will be needed to reduce the stress and suicidal thoughts and improve the positive cognitive attitude and subjective health condition.

• Journal of environmental and Sanitary engineering
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• v.19 no.4 s.54
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• pp.48-60
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• 2004

This study is aimed at examining the relationship between health behaviors practices and physical and psychological stresses of radiological technologists who are working at general hospitals across the country. For this purpose, a survey was conducted to 890 subjects by means of questionnaires from the middle of July to the end of August 2003, which resulted in the following outcomes: 1. From the technical and statistical analysis into the physical and psychological states, the item 'I feel miserable and dejected' scored the highest points of (3.91), implying that most subjects got heavily stressed, while the item 'Life is worth living' recorded (2.59), representing that only a few of them got less stressed. 2. With regard to an analysis of variance depending on their regular exercise, a significant difference appeared in 7 items(Pl, P2, P5, P6, P12, P17, and Pl8)(P<0.05). 3. Out of analysis into such variance as smoking, significant results were found in the items 'I become uncomfortable or disturbed at night' and 'I can solve my own problems'(P<0.05), while no significant difference was confirmed in other items regardless smoking. 4. From the T-test conducted to the independent sample depending on the drive under the influence, a significant difference was shown only in the item 'I feel very exhausted, even eating is a labo'( P<0.05). 5. The T-test with the independent sample of drinking coffee, the item 'I am satisfied with the method and the procedure of things I do' turned out to be significant( P<0.05) while no particular difference was confirmed in other items. In conclusion, it was revealed from the study that the physical and psychological states and health-related practices of radiological technologists seemed to be more affected by regular exercise than by smoking or drinking wine or coffee, a result confirming that the health-related acts are closely associated with the socio-psychological stresses. It is, therefore, strongly suggested that the practice of health-related acts to properly control stress will contribute to promoting health and pre venting disease of radiological technologists.

• Journal of Korean Public Health Nursing
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• v.28 no.1
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• pp.71-86
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• 2014

Purpose: This study was conducted in order to identify factors that predict suicidal ideation and depression according to gender among Korean adults. Method: From the data base of the fifth Korean National Health and Nutritional Examination Survey(KNHANESV-1, 2010), data on 4,894 adults aged 19~64 were used. Data were analyzed by application of the Rao-Scott Chi-Square test and logistic analysis with SAS 9.2. Results: Overall, 8.5% of men and 18.1% of women had suicidal ideation during the last year; 7.5% of men and 17.0% of women had depression during the last two weeks. Risk factors for suicidal ideation include perceived high stress(OR male 3.649, female 2.941), depression(OR male 10.109, female 6.033), poor cognition of health status(OR male 8.115, female 6.664), low economic status(OR male 1.898), and low educational status(OR female 1.631). Risk factors for depression include perceived high stress(OR male 2.678, female 3.686), suicidal ideation(OR male 9.925, female 6.022), non-employed(OR female 1.525), married(OR female 2.392), and physical discomfort(OR female 1.545). Conclusions: Based on the above mentioned results, risk factors of suicidal ideation and depression differed according to gender. Development of various policies and appropriate intervention programs according to gender, that lessen the risk of suicidal ideation and depression for adults is needed.

• The Journal of Korean Medicine
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• v.31 no.4
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• pp.171-177
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• 2010

Objective: To obtain an overview of the status of health-associated factors of Korean high school adolescents. Methods: 2,455 high school students (1,808 boys and 647 girls) filled out questionnairesfor their health-related factors such as physical problems, sleep and exercise. Results: Students sleep about 5.5 hours per day while they exercise only 2.6 hours each week. 14.2% of students skip breakfast every day. 31.0% of students were under severe stress, and 46.4 % has at least one symptom of distresses such as indigestion, headache, frequently catching cold, or muscle pain. 40.7% of the students took a functional supplement, especially vitamins as the most common, and ginseng and herbal drugs as the second and third. Conclusion: These results present general health-associated status of high school students, thus they could be helpful to design medicinal strategies for high school students using traditional Korean medicine.

• Korean Journal of Biological Psychiatry
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• v.14 no.4
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• pp.221-231
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• 2007

Recent researches have shown that important cellular-based autoprotective mechanisms are mediated by heat-shock proteins(HSPs), also called 'molecular chaperones'. HSPs as molecular chaperones are the primary cellular defense mechanism against damage to the proteome, initiating refolding of denatured proteins and regulating degradation after severe protein damage. HSPs also modulate multiple events within apoptotic pathways to help sustain cell survival following damaging stimuli. HSPs are induced by almost every type of stresses including physical and psychological stresses. Our nervous system in the brain are more vulnerable to stress and damage than any other tissues due to HSPs insufficiency. The normal function of HSPs is a key factor for endogenous stress adaptation of neural tissues. HSPs play an important role in the process of neurodevelopment, neurodegeneration, and neuroendocrine regulation. The altered function of HSPs would be associated with the development of several neuropsychiatric disorders. Therefore, an understanding of HSPs activities could help to improve autoprotective mechanism of our neural system. This paper will review the literature related to the significance of HSPs in neuropsychiatric field.

• Genomics & Informatics
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• v.10 no.4
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• pp.244-248
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• 2012

Oxidative stress, which results in an excessive product of reactive oxygen species (ROS), is one of the fundamental mechanisms of the development of hypertension. In the vascular system, ROS have physical and pathophysiological roles in vascular remodeling and endothelial dysfunction. In this study, ROS-hypertension-related genes were collected by the biological literature-mining tools, such as SciMiner and gene2pubmed, in order to identify the genes that would cause hypertension through ROS. Further, single nucleotide polymorphisms (SNPs) located within these gene regions were examined statistically for their association with hypertension in 6,419 Korean individuals, and pathway enrichment analysis using the associated genes was performed. The 2,945 SNPs of 237 ROS-hypertension genes were analyzed, and 68 genes were significantly associated with hypertension (p < 0.05). The most significant SNP was rs2889611 within MAPK8 (p = $2.70{\times}10^{-5}$; odds ratio, 0.82; confidence interval, 0.75 to 0.90). This study demonstrates that a text mining approach combined with association analysis may be useful to identify the candidate genes that cause hypertension through ROS or oxidative stress.

• Journal of Korean Public Health Nursing
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• v.24 no.1
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• pp.82-92
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• 2010

Purpose: This study aimed to identify the incidence and risk factors of suicidal ideation among the elderly in Korea. Methods: This cross-sectional study used secondary data of the 2005 Korean National Health and Nutrition Examination Survey. The participants were 1,097 elderly Koreans who responded to the health survey. Sociodemographics, health related characteristics, and the prevalence of suicidal ideation were obtained through face-to-face interviews. Risk factors of the suicidal ideation were also examined. Descriptive statistics and multivariate logistic regression were used for data analysis. Results: Of the 1,097 respondents, 30.5% had suicidal ideation during the past year. Depression and stress were the important risk factors; others included mobility, pain/discomfort, chronic illness, smoking, sleep, and leisure time physical activity. Sociodemographic characteristics such as gender, education, and marital status affected suicidal ideation. Conclusion: The high frequency of suicidal ideation in the elderly suggests the necessity of community-based interventions directed at depression and stress.

• Journal of Oriental Neuropsychiatry
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• v.24 no.spc1
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• pp.15-22
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• 2013

Objectives : The Hwabyung Research Center of The Korean Society Of Oriental Neuropsychiatry attempted to produce clinical guidelines for doctors of Korean medicine for the treatment of Hwabyung. Methods : A standard guideline development process was followed. Relevant literature was identified by a review of bibliographies. The operational criteria were used to rate the quality of scientific evidence, and the line of treatment recommendations included a consensus clinical opinion. This section of "the status of Hwabyung in Korea" is 2 out of 5 articles drafted and reviewed by clinicians. Results : Hwabyung is changed depending on the time and have a risk of relapse. Like the previous studies, Female and lower socio-economic and educational level people suffers Hwabyung frequently. But recently number of Male Hwabyung patients increases. Recovery of Hwabyung is involved in depression, anxiety, stress. Hwabyung is related to Major depressive disorder, generalized anxiety disorder, somatoform disorder and diseases of the digestive system. Conclusions : This study was observed for the progression of Hwabyung. Hwabyung is a long-term disease associated with depression, anxiety and stress. Hwabyung is accompanied by physical and psychological symptoms and degrades the quality of life.