• Journal of Biosystems Engineering
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• v.21 no.4
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• pp.429-435
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• 1996

A wind tunnel consisting of two air flow conditioners with polycarbonate pipes, a plant growth room, a suction fan and fan controller, and fluorescent lamps, was designed to investigate the interactions between the growth of plug seedlings under artificial light and their Physical environments. Light transmissivities in the plant growth room based on the photosynthetic photon flux density and photosynthetically active radiation was appeared to be 96.3% and 96.8%, respectively. Measurement showed a uniformity in the vertical profiles of air current speed at the middle and rear regions of plug trays in wind tunnel. This result indicated that the development of a wind tunnel based on the design criteria of the American Society of Mechanical Engineers was adequate. Air current speed inside the plug stand was significantly decreased due to the resistance by the leaves of plug seedlings and boundary layer developed over and below the plug stand. Driving force to facilitate the diffusion of gas inside the plug stand might be regarded as extremely low. Aerodynamic characteristics above the plug stand under artificial light were investigated. As the air current speed increased, zero plane displacement decreased but roughness length and frictional velocity increased. Zero plane displacement linearly increased with the average height of plug seedlings. The wind tunnel developed in this study would be useful to investigate the effects of air current speed on the microclimate over and inside the plug stand and to collect basic data for a large-scale plug production under artificial light in a semi-closed ecosystem.

• Journal of Nutrition and Health
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• v.28 no.9
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• pp.862-871
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• 1995

This study was designed to investigate the effectiveness of ginseng intakes in modifying serum lipid profiles and plasma clotting factors. The participants in this study were 47 normal healthy volunteers(men 24, women 23) with an age range of 35-49 years and a mean age of 41 years residing in Taejon. Based on the diet intakes, subjects were classed into one of three groups : control, vegetarian, and ginseng consumed over 3-4 years. There was no significant difference in their physical characteristics. Dietary calorie intakes were not significantly different in subjects. The ratio of energy intake in the control and ginseng consumed group was 63-64% : 20-21% : 15-16%(Cho : Fat : Pro), but 70-73% : 13-14% :14-15%(Cho : Fat : Pro) in the vegetarians. The intakes of animal food in the vegetarian was significantly lower than the control and ginseng consumed group in men. The ratio of P/S(1.27) was the highest in the vegetarians. Venous blood samples were taken for serum lipid profiling, plasma clotting assay and platelet function. The concentration of serum triglyceride in the men ginseng group is significantly lower than those of the men control group. Serum lipid profiles values of the men ginseng group, such as total cholesterol and phospholipid were lower those of the men control group, but higher those of the men vegetarian group. the serum lipid profile in the women were not significant, but total cholesterol, triglyceride and LDL cholesterol levels in the ginseng groups were low. The concentration of HDL cholesterol was not significantly different. Platelet cell count and platelet aggregation were low in the ginseng groups. APTT(Activated Partial thromboplastin time) was significantly elongated in ginseng groups in the normal range. In seems that the major beneficial effects of ginseng intakes in especially men were on the blood concentrations of triglyceride, total cholesterol and elongation of plasma clotting time.

• Nutrition Research and Practice
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• v.3 no.4
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• pp.307-314
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• 2009

This study was conducted to evaluate the effects of a body weight control program with supplementation of sea tangle (20 g/day) on 22 female college students. The contents of the program for 8 weeks contained diet therapy, exercise and behavioral modification through nutrition education. Body composition, dietary habit scores, serum lipid profiles, daily nutrient intakes and the quality of life were assessed at the beginning and at the end of the program. Average age of subjects and height were 20.8 years and 161.9 cm, respectively. After 8 weeks, there were significant reductions in body weight, body fat mass, percent body fat, waist-hip ratio and BMI. The dietary habit score such as a balanced diet, regularity of mealtime, overeating, eating while watching TV or using the computer and eating salty food were increased significantly. Serum lipid levels such as total cholesterol level, LDL-cholesterol level and triglyceride level were decreased but not significantly. There were decreases in intake of energy, protein and fat and increases in intakes of dietary fiber, folic acid, calcium and potassium from the beginning to the end of the program. There were significant improvements on subcomponents of quality of life; physical functioning, general-health and vitality. The limitation of this study was the fact that there was no control group, but an overall evaluation suggests the 8-week body weight control program consisting of diet therapy, exercise and behavioral modification with supplementation of sea tangle would be helpful to improve the body composition, dietary habits, daily nutrient intakes and quality of life in Korean female college students.

• Journal of Microbiology and Biotechnology
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• v.16 no.12
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• pp.1954-1960
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• 2006

The effects of the exopolymers of Aureobasidium pullulans SM-2001 containing $\beta$-1,3/1,6-glucan on formalin-induced chronic inflammation were observed. Doses of 62.5, 125, and 250 mg/kg of the exopolymers were orally administered once a day for 10 days to formalin-induced chronic inflammatory mice (0.02 ml of 3.75% formalin was subaponeurotically injected into the left hind paw), and then the bilateral hind-paw thickness and volume were measured daily, while the paw wet-weight, histological profiles, and histomorphometrical analyses were conducted at termination. The results were compared with those for diclofenac, indomethacin, and dexamethasone (intraperitoneally injected) 15 mg/kg-dosed groups. All the animals were sacrificed 10 days after dosing. As a result of the formalin injection, a marked increase in the difference between the intact and formalin-induced paw thickness and volume was detected in the formalin-injected control compared with that in the intact control with time, plus at the time of sacrifice, the difference in the paw wet-weights was also dramatically increased. In a histological and histomorphometrical analysis, severe histological profiles of chronic inflammation were detected in the formalin-injected control with a marked increase in the thickness of the skin of the dorsum pedis. However, these formalin-induced chronic inflammatory changes were significantly and dose-dependently decreased by the exopolymer treatment. In conclusion, the exopolymer treatment inhibited the chronic inflammatory response induced by formalin injection in the mice. However, somewhat low efficacies were detected compared with those for the diclofenac-, indomethacin-, and dexamethasone-treated groups.

• The Korean Journal of Physiology and Pharmacology
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• v.15 no.1
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• pp.23-29
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• 2011

Melatonin, which is the main product of the pineal gland, has well documented antioxidant and immune-modulatory effects. Macrophages produce molecules that are known to play roles in inflammatory responses. We conducted microarray analysis to evaluate the global gene expression profiles in response to treatment with melatonin in lipopolysaccharide (LPS) activated RAW 264.7 macrophage cells. In addition, eight genes were subjected to real-time reverse transcription polymerase chain reaction (RT-PCR) to confirm the results of the microarray. The cells were treated with LPS or melatonin plus LPS for 24 hr. LPS induced the up-regulation of 1073 genes and the down-regulation of 1144 genes when compared to the control group. Melatonin pretreatment of LPS-stimulated RAW 264.7 cells resulted in the down regulation of 241 genes and up regulation of 164 genes. Interestingly, among genes related to macrophage-mediated immunity, LPS increased the expression of seven genes (Adora2b, Fcgr2b, Cish, Cxcl10, Clec4n, Il1a, and Il1b) and decreased the expression of one gene (Clec4a3). These changes in expression were attenuated by melatonin. Furthermore, the results of real-time PCR were similar to those of the microarray. Taken together, these results suggest that melatonin may have a suppressive effect on LPS-induced expression of genes involved in the regulation of immunity and defense in RAW 264.7 macrophage cells. Moreover, these results may explain beneficial effects of melatonin in the treatment of various inflammatory conditions.

• Journal of the Korean Institute of Telematics and Electronics
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• v.26 no.6
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• pp.63-70
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• 1989

The ion beam extracted from the AuGe liquid metal ion source was implanted into GaAs substrate. The surface composition and the structure of ion implanted samples were investigated by AES, RHEED, SEM and EPMA. The depth profiles measured by AES were compared with the results of Monte Carlo simulation based on the two-body collision. As the results of AuGe ion implantation the preferential sputtering of As were revealed by AES and EPMA, and the outdiffusion of Ga and Ge was investigated by 300$^{circ}C$ annealing. The Au and Ge depth profiles measured by AES agreed with the results of Monte Carlo simulation based on the two-body collision.

• The Bulletin of The Korean Astronomical Society
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• v.42 no.2
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• pp.87.2-87.2
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• 2017

RR~Telescopii is a symbiotic nova exhibiting accretion activities through gravitational capture of the slow stellar wind from a Mira variable. We present high resolution spectra of RR~Tel obtained with MIKE and the 6.5 m Magellan-Clay telescope, in which we find broad features with FWHM exceeding $10{\AA}$ at 6545, 6825, 7082, 7023 and $7053{\AA}$. They are formed through Raman-scattering with atomic hydrogen of far-UV He II 1025, O~VI 1032, $1038{\AA}$ and C II 1036 and $1037{\AA}$. We compute the Raman conversion efficiencies using the case B recombination theory for He II emissions, which are used in turn to infer the intrinsic line luminosities of O VI and C II. The Raman O~VI features are characterized by double-peaked profiles with a peak separation ~ 60km/s, pointing out the presence of an accretion disk with a physical size of ~ sub AU. In contrast, Raman C II features exhibit profiles with a simple peak and a narrower width ~40 km/s, indicating that C II is formed in a much more extended region. The weak C II multiplet at 1335, $1336{\AA}$ found in the IUE spectral archive and the absence of C II 1036, $1037{\AA}$ in the FUSE archive show that far-UV C II lines suffer heavy interstellar extinction consistent with the distance of ~ 2.5 kpc to RR Tel.

• Journal of The Korean Astronomical Society
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• v.28 no.2
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• pp.245-253
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• 1995

We have analyzed the time series of Ca II H,K and ${\lambda}8498$ line profiles taken for a sunspot (SPO 5007) with the Echelle spectrograph attached to Vacuum Tower Telescope at Sacramento Peak Solar Observatory. Each set of spectra was taken simultaneously for 20 minutes at a time interval of 30 seconds. A total of 40 photographic films for each line was scanned by a PDS at Korea Astronomy Observatory. The central peak intensity of Ca II H ($I_{max}$), the intensity measured at ${\Delta}{\lambda}=-0.1{\AA}$ from the line center of ${\lambda}8498(I_{{\lambda}8489})$, the radial velocity ($V_r$) and the Doppler width (${\Delta}{\lambda}_D$) estimated from Ca II H have been measured to study the dynamical behaviors of the sunspot chromosphere. Fourier analysis has been carried out for these measured quantities. Our main results are as follows: (1) We have confirmed the 3-minute oscillation being dominant throughout the umbra. The period of oscillations jumps from 180 sec in the umbra to 500 to 1000 sec in the penumbra. (2) The nonlinear character of the umbral oscillation is noted from the observed sawtooth shaped radial velocity fluctuations with amplitudes reaching up to $5{\sim}6\;km/sec$. (3) The spatial distribution of the maximum powers shows that the power of oscillations is stronger in the umbra than in the penumbra. (4) The spatial distributions of the time averaged < $I_{max}$ > and < $V_r$ > across the spot are found to be nearly axially symmetric, implying that the physical quantities derived from the line profiles of Ca II H and ${\lambda}8498$ are inherently associated with the geometry of the magnetic field distribution of the spot. (5) The central peaks of the CaII H emission core lead the upward motions of the umbral atmosphere by $90^{\circ}$, while no phase delay is found in intensities between $I_{max}$ and $I_{{\lambda}8498}$, suggesting that the umbral oscillation is of standing waves.

• The Journal of Pediatrics of Korean Medicine
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• v.31 no.1
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• pp.12-24
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• 2017

Objectives The purpose of this study was to validate the biopsychological structure of Sasang Personality Questionnaire (SPQ) measuring Yin-Yang temperament with Junior version of Temperament and Character Inventory (JTCI) for temperament and Body Mass Index (BMI) and Pondera Index (PI) for physical constitution in elementary school students. Methods 903 Korean elementary school students (430 boys and 473 girls) completed SPQ, JTCI, and height and weight measures. Then they were analyzed by their genders and age groups. The correlation between SPQ and JTCI subscales were examined. The differences found in the SPQ and JTCI subscales, BMI and PI among high (30%), middle (40%), and low (30%) SPQ groups were investigated by analysis of variance. The profile analysis was also performed to compare JTCI subscale profiles of three SPQ total score groups. Results The SPQ score was significantly (p<0.001), and positively correlated with the JTCI Novelty-Seeking and negatively with the JTCI Harm-Avoidance. The JTCI Novelty-Seeking score of high SPQ group was significantly (p<0.001) higher than that of low SPQ group, and the JTCI Harm-Avoidance score of low SPQ group was significantly higher than that of high SPQ group. The JTCI subscale profiles for three SPQ groups were significantly (p<0.001) different for boys and girls. Significant correlations between BMI and SPQ were not found. PI and BMI of high and low SPQ groups were not significantly different. Conclusions The SPQ was shown to have robust biopsychological structure in elementary school students. It would be useful clinical measures for Sasang typology in pediatric patients.

• The Journal of Pediatrics of Korean Medicine
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• v.33 no.3
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• pp.30-41
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• 2019

Objectives Development of objective clinical measure for analyzing pediatric weakness has been studied. However, there is no gold standard clinical measures with acceptable validity and reliability were not provided yet and these has been major issue for clinics. Methods Some Korean medicine hospital outpatients (n=324) were recruited as participants, and 55 preliminary questions were given. Pediatric Weakness Scale (PWS) with five subscales and thirty questions were developed using factor analysis and item analysis. The internal consistency of PWS subscales were examined with using Cronbach's alpha. The correlations between PWS subscales and physical characteristics of Body Mass Index (BMI) and Ponderal Index (PI) were attested using Pearson's correlation. The differences between PWS subscale scores and profiles among 3 to 13 years old children were examined using profile analysis and ANOVA by gender. Results PWS five subscales explained 49.1% of total variance, and the range of Cronbach's alpha was from 0.700 to 0.803. The range of correlation coefficient between PWS total score and five subscales was from 0.643 to 0.748, and the PWS total score was significantly (p<0.001) correlated positively with BMI (r=-0.237) and negatively with PI (r=-0.280). The scores and profiles of PWS five subscales, BMI and PI were found to be significantly different among the all age groups. Conclusions Objective and validated clinical measure for analyzing pediatric weakness with five subscales was developed in current study, and foundations for screening, managing and treating pediatric weakness during the development were established as well. This study would contribute to the integrative education and clinical practice of the Eastern and Western medicine.