• Title/Summary/Keyword: photo sensitivity

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Prediction of Photo-Carcinogenicity from Photo-Ames Assay (Photo-Ames Assay를 이용한 광발암성 예측)

  • Hong Mi Young;Kim Ji Young;Chung Moon Koo;Lee Michael
    • Environmental Mutagens and Carcinogens
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    • v.25 no.1
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    • pp.6-12
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    • 2005
  • Many compounds might become activated after absorption of UV light energy. In some cases, the resulting molecule may undergo further biological reaction of toxicological relevance related especially to the photo-carcinogenicity resulting from photo-genotoxicity. However, no regulatory requirements have been issued with the exception of guideline issued by the Scientific Committee of Cosmetology, Commission of the European Communities (SCC/EEC) on the testing of sunscreens for their photo-genotoxicity. Thus, the objectives of this study are to investigate the utility of photo-Ames assay for detecting photo-mutagens, and to evaluate its ability to predict rodent photo-carcinogenicity. Photo-Ames assay was performed on five test substances that demonstrated positive results in photo-carcinogenicity tests: 8-methoxypsoralen (photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation), chlorpromazine (an aliphatic phenothiazine an a-adr-energic blocking agent), lomefloxacin (an antibiotic in a class of drugs called fluoroquinolones), anthracene (a tricyclic aromatic hydrocarbon a basic substance for production of anthraquinone, dyes, pigments, insecticides, wood preservatives and coating materials) and retinoic acid (a retinoid compound closely related to vitamin A). Out of 5 test substances, 3 showed a positive outcome in photo-Ames assay. With this limited data set, an investigation into the predictive value of this photo-Ames test for determining the photo-carcinogenicity showed that photo-Ames assay has relatively low sensitivity (the ability of a test to predict carcinogenicity). Thus, to determine the use of in vitro genotoxicity tests for prediction of carcinogenicity,' several standard photo-genotoxicity assays should be compared for their suitability in detecting photo-genotoxic compounds.

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Decolorization of Rhodamine B by Fenton, Fonton-like and Photo-Fenton-like Oxidation (펜톤, 펜톤-유사 및 광-펜톤-유사 반응을 이용한 Rhodamine B의 탈색)

  • Kim, Dong-Seog;Park, Young-Seek
    • Journal of Environmental Health Sciences
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    • v.33 no.2 s.95
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    • pp.150-157
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    • 2007
  • The chemical and photochemical decolorization of Rhodamine B (RhB) in water has been carried out by Fenton, Fenton-like and photo-Fenton-like process. The effect of applied $H_2O_2,\;Fe^{2+}$ dosage (Fenton process), $H_2O_2,\;Fe^{\circ}$ dosage (Fenton-like and photo-Fenton-like process), UV light power (photo-Fenton-like process) pH (all processes) have been studied. The results obtained showed that more than 98% of color removal was obtained for the RhB solutions in every process. However, Fenton-like process was not suitable for the color removal of RhB because Fenton-like process was required much more reagents than Fenton and photo-Fenton-like process. The Fenton and photo-Fenton-like process showed similar reagents need. Optimum pH for three processes in this study is about pH 3. The relative order of sensitivity for pH of each process was: Fenton-like > photo-Fenton-like > Fenton.

Optical Ozone Monitor Using UV Source

  • Chung, Wan-Young
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.49-52
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    • 2003
  • Two types of ozone monitors using UV absorption method were tried in consideration of cost of the monitor and precision in measuring. The high concentration ozone monitor for high concentration real time ozone monitoring from ozone generator was composed of a low pressure mercury lamp as UV source, a photo multiplier tube as UV detector and signal processing unit for the most part. This structure could be very useful for low price high concentration ozone monitor due to simple system structure and fairly good monitoring characteristics. The developed system showed good linear output characteristics to ozone in the measuring concentration range of 0.05 and 2 wt.%. For accuracy ambient ozone monitoring in ambient in ppm level, the system composed of a high power pulsed xenon lamp as UV source, an optical spectrometer with a high sensitivity linear CCD array as UV detector and signal processing unit in brief speaking was proposed our study for the first time in the world. The developed system showed good linearity and sensitivity in relative low measuring range between 10ppm and 10,000ppm, and showed some feasibility of high resolution ozone monitor using CCD array as photodetector.

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Evaluation of Thin-Film Photodevices and Development of Artificial Retina

  • Kimura, Mutsumi;Shima, Takehiro;Yamashita, Takehiko;Nishizaki, Yoshitaka;Hara, Hiroyuki
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08b
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    • pp.1745-1748
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    • 2007
  • First, thin-film photodevices are evaluated, and a p/i/n thin-film phototransistor (TFPT) is recommended because the photo-induced current is relatively high and independent of the applied voltage. Next, an artificial retina is developed using the p/i/n TFPTs, and it is found that it can detect photo illuminance profile with sensitivity control.

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Small Methane Detection System using Optical Spectrum Characteristics (분광특성을 이용한 소형의 메탄 가스 감지 시스템)

  • Jo, Kyung-Hwa;Lyu, Geun-Jun;Kim, Eung-Soo
    • Journal of Sensor Science and Technology
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    • v.20 no.1
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    • pp.53-57
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    • 2011
  • We developed a small methane detection system because methane gas is used in many areas and is dangerous. The developed system consisted of LD(Laser Diode) tuned a wavelength of $1.65\;{\mu}m$, two mirrors to collect a laser beam, photo detector. It could detect methane gas at a long range and its sensitivity was 1.98 V/$CH_4%$.

Photo-induced Electron Transfer(PET) Based Luminescent Chemosensors Detecting Hazardous Substances (광유발 전자전이를 이용한 유해물질 인식 형광 화학센서의 개발)

  • Yoon, Sung-Ho
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.25 no.9
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    • pp.711-716
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    • 2012
  • Based on both organic synthesis and theoretical calculations on the effects of molecular orbital energy levels of amines on the fluorescence properties of the fluorophore, fluorescent "turn-on" chemosensors detecting hazardous substances, including aldehyde chemicals and $Hg^{2+}$ ion, were developed.

Development of Photo-diode for LOC fluorescence detector (LOC 형광검출 소자를 위한 광 다이오드의 제작 및 특성 평가)

  • Kim, Ju-Hwan;Shin, Kyeong-Sik;Kim, Yong-Kook;Kim, Sang-Sik;Ju, Byeong-Kwon
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2003.04a
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    • pp.100-103
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    • 2003
  • Signal detection technologies such as fluorescence, charge and electrochemical detection used in the monolithic capillary electrophoresis system to convert the biochemical reaction into the electrical signal. The fluorescence detection using photodiodes that measure fluorescence emitted from eluting molecules is widely used for the monolithic capillary electrophoresis system. In this paper, in order to fabricate a photosensor has the increased sensitivity, we investigated on the sensitivity of general type and p-i-n type diode. The p-i-n diode has higher sensitivity than photodiode. Considering these results, we fabricated p-i-n diodes on the high resistive$(4k{\Omega}{\cdot}cm)$ wafer into rectangle and finger pattern and compared internal resistance of each pattern. The internal resistance of p-i-n diode can be decreased by the application of finger pattern has parallel resistance structure from $571{\Omega}$ to $393{\Omega}$.

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Development of Infusion Pump System using Photodiode Array (광 다이오드 어레이 센서를 이용한 인퓨전 펌프 시스템의 개발)

  • Kwon, Jang-Woo;Park, Jung-Sun;Lee, Dong-Hun;Lee, Eung-Huyk;Hong, Seung-Hong
    • Journal of Sensor Science and Technology
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    • v.5 no.3
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    • pp.65-73
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    • 1996
  • One of the important factor in drug stuffs to a patient is to inject exact amount with stable flow rates. Since improper injection amount and flow rates would cause bad effect to recovery of a patient, the detecting sensors with high sensitivity is required for an injection pump systems' performance improvement. In this study, the three sensors, piezo film sensor, photo transistor and photo array, were compared to find best one for an injection pump monitoring system. Using suggested data processing technique and photo array sensors, we could minimize the effect of interference, disturbance, illumination, and sensitivity change caused by sensor's position. According to the experiments, the photo array showed the higher reliance than any other the three types of sensors.

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Modelling and Sensitivity Analysis for the Performance Improvement of a Spin Coater (스핀 코너 성능향상을 위한 모델링 및 민감도 해석)

  • 권태종;채호철;한창수;정진태;안강호
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.9 no.6
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    • pp.96-102
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    • 2000
  • Spinning mechanism is generally used in coasting process on grass plates. Rebounding PR(Photo Resist) which leads to occur inferiority of coating process is caused by vibrational energy of whole coating system. In this study, the sensitivity analysis is performed to analyze and reduce vibrational terms in the spin coating system. The sensitivity analysis is bared on the numerical expression of this system. By the bond graph method. power flow of each system is represented by some basic bond graph elements. Any energy domain system is modeled using the unified elements. The modelled spin coater system is verified with power spectrum data measured by FFT analyzer. As the results of verifying model parameters and sensitivity analysis, principal factors causing vibration phenomenon are mentioned. A study on vibration method in the spin coating system is discussed.

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Semiconductor Process Inspection Using Mask R-CNN (Mask R-CNN을 활용한 반도체 공정 검사)

  • Han, Jung Hee;Hong, Sung Soo
    • Journal of the Semiconductor & Display Technology
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    • v.19 no.3
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    • pp.12-18
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    • 2020
  • In semiconductor manufacturing, defect detection is critical to maintain high yield. Currently, computer vision systems used in semiconductor photo lithography still have adopt to digital image processing algorithm, which often occur inspection faults due to sensitivity to external environment. Thus, we intend to handle this problem by means of using Mask R-CNN instead of digital image processing algorithm. Additionally, Mask R-CNN can be trained with image dataset pre-processed by means of the specific designed digital image filter to extract the enhanced feature map of Convolutional Neural Network (CNN). Our approach converged advantage of digital image processing and instance segmentation with deep learning yields more efficient semiconductor photo lithography inspection system than conventional system.