• Title/Summary/Keyword: permeability model

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EVALUATION OF IN VITRO SKIN PERMEATION OF UV FILTERS

  • Song, Young-Sook;Kim, Hyo-Joong;Lee, Cheon-Koo;Cho, Wan-Goo;Kang, She-Hoon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.24 no.3
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    • pp.38-44
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    • 1998
  • The skin permeation and the skin primary irritation of two UV filters from caprylic capryl triglyceride (oil), oil in water (O/W) and water in oil (W/O) emulsions, were evaluated. We selected octyl moth-oxycinnamate (OMC) broadly used in cosmetics and polymeric sunscreen agent (PSA, average MW: 2,000) synthesized by the coupling reaction of 2-ethylhexyl 4-hydroxycinnamate with poly vinylbenzyl chloride, as model UV filters. For in vitro skin permeation experiments, Franz diffusion cells (effective diffusion area:1.766cm) and the excised skin of female hairless mouse aged 8 weeks were used. Oil or emulsion containing UV filters was applied in the donor compartment. The skin primary irritation was evaluated with fe-male guinea pigs (8-10 weeks,350-400 g). In oil and emulsions, the skin permeability and the skin primary irritation of PSA were lower than those of OMC. The skin permeability of UV filters was lower when they were in oil-in-water emulsion (OIW) than water-in-oil emulsion (W/O). We suggest that O/W system would be more useful when compared with W/O system, and PSA could be a good candidate for a future sunscreen agent for reducing the skin irritation.

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Clogging behavior of recycled aggregates and crushed stone as horizontal drains in soft ground (연약지반에서 수평배수재용 순환골재와 쇄석의 막힘 거동)

  • Lee, Dal-Won;Noh, Jae-Jin
    • Korean Journal of Agricultural Science
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    • v.40 no.3
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    • pp.253-260
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    • 2013
  • In this study, laboratory model test carried out to present the suitable range of particle size distribution and clogging behavior of recycled aggregates and crushed stone as horizontal drains in soft ground. The recycled aggregates and crushed stone showed clogging phenomenon because the top fill material and bottom clay inflow into the horizontal drains. The pp mat was the most effective method to minimize clogging phenomenon. The horizontal coefficient of permeability in case of installing the pp mat showed largely 2.1 times more than the case of not installing. When the pp mat is not installing, the thickness of fine grained soil inflow into the horizontal drains showed 6.7~13.3% range in top fill material and 3.3~6.7% range in bottom clay. Overall, the reduction of the discharge capacity by fine grained soil inflow showed small in recycled aggregates and crushed stone. Also, the appropriate criterion range of particle size distribution is presented to make use of a horizontal drains in soft ground on the basis of laboratory test.

Resonance and Response of the Submerged Dual Buoy/Porous-Membrane Breakwaters in Oblique Seas

  • Kee, S.T.
    • Journal of Ocean Engineering and Technology
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    • v.15 no.2
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    • pp.22-32
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    • 2001
  • The numerical investigation of obliquely incident wave interactions with fully submerged dual buoy/porous-membrane floating breakwaters placed in parallel with spacing is studied based on linear potential theory and Darcy's law. The numerical solutions are obtained by using a discrete-membrane dynamic model and second-kind modified Bessel function distribution over the entire boundaries of fluid regions. First, numerical solutions for an idealized dual submerged system without buoys are obtained. Second, a more practical dual submerged system with membrane tension provided by buoys at its tops is investigated by the multi-domain boundary element method particularly devised for dual buoy/porous-membrane problems with gaps. The velocity potentials of wave motion are coupled with porous-membrane deformation, and solved simultaneously since the boundary condition on porous-membrane is not known in advance. The effects of varying permeability on membranes and wave characteristics are discussed for the optimum design parameters of systems previously studied. The inclusion of permeability on membrane eliminates the resonances that aggravate the breakwater performance. The system is highly efficient when waves generated by the buoys and membranes were mutually canceled and its energy at resonance frequency dissipates through fine pores on membranes.

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Hydraulic behavior of a subsea tunnel in a ground with fractured-zones (파쇄대를 통과하는 해저터널의 수리거동에 관한 연구)

  • Shin, Jong-Ho;Choi, Kyu-Cheol
    • Proceedings of the Korean Geotechical Society Conference
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    • 2008.10a
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    • pp.1571-1580
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    • 2008
  • Subsea tunnels that link land to island and among nations for transportation, efficient development of limited surface and pursuit of economic development should be designed to support pore water pressure on the lining. It is generally constructed in the bed rock of the sea bottom. When the tunnel excavation face meets fractured-zones below sea bottom, collapse may occur due to an increase of pore water pressure and large inflow. Such an example can be found in the Norwegian subsea tunnel experiences in 1980's. In this study hydraulic behavior of tunnel heading is investigated using numerical method based on the collapse of Norwegian subsea tunnel. The effect of pore water pressure and inflow rate were mainly concerned. Horse-shoe shaped model tunnel which has 50 m depth from the sea bottom is considered. To evaluate hydraulic performance, parametric study was carried out for varying relative permeability. It is revealed that pore water pressure has increased with an increase of sea depth. Especially, at the fractured-zone, pore water pressure on the lining has increased significantly. Inflow rate into tunnel has also increased correspondingly with an increase in sea depth. S-shaped characteristic relation between relative permeability and normalized pore water pressure was obtained.

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Current Distribution and Effective Resistance in the Rail of a Distributed-type Railgun (분포형 레일건 레일에서의 전류분포 및 실효저항)

  • 임달호;구태만
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.37 no.10
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    • pp.694-701
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    • 1988
  • Distributed-type railguns are designed to maintain the armature current and the length between the armature and the current-feed region nearly constant with time. This paper deals with factors affecting current distribution, effective resistance and effective skin depth in the rail of a distributed-type railgun. Analytical solutions for the current distributions and resistance in the rail are presented for a simple two-dimensional model under steady-state contions. For diffusion limited current, it is found that effective rail resistance is proportional to the square root of the relative velocity, the permeability of the rail and the length between the armature and that effective skin depth of the rail is proportional to the square root of the length and inversely proportional to the square root of the permeability, the conductivity and the velocity.

Pharmaceutical Studies on Chitosan Matrix: Controlled release of aspirin from chitosan device

  • Lee, Chi-Young;Kim, Sung-Ho
    • Archives of Pharmacal Research
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    • v.10 no.2
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    • pp.88-93
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    • 1987
  • Chitosan ($\beta$-D-glucosaminan) is chemically prepared from chitin (N-acetyl-$\beta$- D-glucosaminan) which is an unutilized natural resource. We now report on the suitability of the chitosan matrix for use as vehicles for the controlled release of drugs. Salicylic acid and aspirin were used as model drugs in this study. The permeation of salicylic acid in the chitosan membranes was determined in a glass diffusion cell with two compartments of equal volume. Drug release studies on the devices were conducted in a beaker containing 5% sodium hydroxide solution. Partition coefficient (Kd) value for acetate membrane (472) is much greater than that for fluoro-perchlorate chitosan membrane (282). Higher Kd value for acetate chitosan membrane appears to be inconsisstent with the bulk salicylic acid concentration. The permeability constants of fluoro-perchlorate and acetate chisotan membranes for salicylic acid were 3.139 ${\times}10^{-7}cm^2$ min up to 60 min and that of 30% aspirin in the devices was 4.739${\times}10^{-7}cm^2$sec upto 60 min. As the loading dose of aspirin in a chitosan device increased, water up-take of chitosan device increased, but in case of salicylic acid it decreased. The release rate increased with increase in the molecular volume of the drugs. Thses result suggest that the release mechanism may be controlled mainly by diffusion through pores.

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A Study on the Variation of Magnetic Field Intensity and Short Current by Coating Material of Spray in AF Track Circuits (AF궤도회로에서 코팅재에 의한 자계의 세기 및 단락전류 변화에 대한 연구)

  • Kim, Min-Seok;Oh, Sea-Hwa;Park, Yong-Gul;Lee, Jong-Woo
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.60 no.3
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    • pp.552-559
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    • 2011
  • There is a method for offering continuous information by AF track circuits. Magnetic fields are formed by current through rails in the AF track circuit systems. So, the continuous information is received by the magnetic fields on a on-board antenna. Coating materials of spray on rails are researched to decrease defects such as head check, shelling, corrugation, squats and so on in Germany. Currently, a coating method of rail construction is proposed by using the ceramics in Korea. When deciding physical characteristic of the coating material of spray, researches are required about variation of flux density and resistivity by using the coating material of spray. In case that the flux density is much lower than existing value, the information for train control is not transmitted to the on-board antenna. In this paper, inductance on rails is calculated and a model is presented about variation of the magnetic field intensity and resistivity in the AF track circuit. Standard permeability of the coating material of spray is proposed. Also, standard resistivity of the coating material of spray is presented by analyzing short current.

Effect of Rock Mass Properties on Coupled Thermo-Hydro-Mechanical Responses at Near-Field Rock Mass in a Heater Test - A Benchmark Sensitivity Study of the Kamaishi Mine Experiment in Japan

  • Hwajung Yoo;Jeonghwan Yoon;Ki-Bok Min
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.21 no.1
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    • pp.23-41
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    • 2023
  • Coupled thermo-hydraulic-mechanical (THM) processes are essential for the long-term performance of deep geological disposal of high-level radioactive waste. In this study, a numerical sensitivity analysis was performed to analyze the effect of rock properties on THM responses after the execution of the heater test at the Kamaishi mine in Japan. The TOUGH-FLAC simulator was applied for the numerical simulation assuming a continuum model for coupled THM analysis. The rock properties included in the sensitivity study were the Young's modulus, permeability, thermal conductivity, and thermal expansion coefficients of crystalline rock, rock salt, and clay. The responses, i.e., temperature, water content, displacement, and stress, were measured at monitoring points in the buffer and near-field rock mass during the simulations. The thermal conductivity had an overarching impact on THM responses. The influence of Young's modulus was evident in the mechanical behavior, whereas that of permeability was noticed through the change in the temperature and water content. The difference in the THM responses of the three rock type models implies the importance of the appropriate characterization of rock mass properties with regard to the performance assessment of the deep geological disposal of high-level radioactive waste.

Analysis of Dynamic Characteristics of 20 kW Hydrogen Fuel Cell System Based on AMESet (AMESet 기반 20 kW급 수소 연료전지 시스템 동특성 모델 해석)

  • JONGBIN WOO;YOUNGHYEON KIM;SANGSEOK YU
    • Journal of Hydrogen and New Energy
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    • v.34 no.5
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    • pp.465-477
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    • 2023
  • In proton exchange membrane fuel cell (PEMFC), proper thermal management of the stack and moisture generation by electrochemical reactions significantly affect fuel cell performance. In this study, the PEMFC dynamic characteristic model was developed through Simcenter AMESim, a development program. In addition, the developed model aims to understand the thermal resin balance of the stack and performance characteristics for input loads. The developed model applies the thermal management model of the stack and the moisture content and permeability model to simulate voltage loss and stack thermal behavior precisely. This study extended the C based AMESet (adaptive modeling environment submodeling tool) to simulate electrochemical reactions inside the stack. Fuel cell model of AMESet was liberalized with AMESim and then integrated with the balance of plant (BOP) model and analyzed. And It is intended to be used in component design through BOP analysis. The resistance loss of the stack and thermal behavior characteristics were predicted, and the impact of stack performance and efficiency was evaluated.

3D numerical model for wave-induced seabed response around breakwater heads

  • Zhao, H.Y.;Jeng, D.S.;Zhang, Y.;Zhang, J.S.;Zhang, H.J.;Zhang, C.
    • Geomechanics and Engineering
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    • v.5 no.6
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    • pp.595-611
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    • 2013
  • This paper presents a three-dimensional (3D) integrated numerical model where the wave-induced pore pressures in a porous seabed around breakwater heads were investigated. Unlike previous research, the Navier-Stokes equation is solved with internal wave generation for the flow model, while Biot's dynamic seabed behaviour is considered in the seabed model. With the present model, a parametric study was conducted to examine the effects of wave and soil characteristics and breakwater configuration on the wave-induced pore pressure around breakwater heads. Based on numerical examples, it was found that the wave-induced pore pressures at breakwater heads are greater than that beneath a breakwater. The wave-induced seabed response around breakwater heads become more important with: (i) a longer wave period; (ii) a seabed with higher permeability and degree of saturation; and (iii) larger angle between the incident waves and breakwater. Furthermore, the relative difference of wave-induced pore pressure between fully-dynamic and quasi-static solutions are larger at breakwater heads than that beneath a breakwater.