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Systematic review of the effect of omega-3 fatty acids on improvement of blood flow while focused on evaluation of claims for health functional food (건강기능식품의 기능성을 중심으로 한 오메가-3 지방산 함유유지의혈행개선 효과에 대한 체계적 고찰)

  • Jeong, Sewon;Kim, Ji Yeon;Paek, Ju Eun;Kim, Joohee;Kwak, Jin Sook;Kwon, Oran
    • Journal of Nutrition and Health
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    • v.46 no.3
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    • pp.226-238
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    • 2013
  • Omega-3 polyunsaturated fatty acids are essential fatty acids because humans cannot synthesize them de novo and must obtain them in their diet. Fish and fish oil are rich sources of omega-3 fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Significant evidence of the beneficial role of dietary intake of omega-3 fatty acids in blood flow has been reported and putative mechanisms for improvement of blood flow include anti-thrombotic effects, lowered blood pressure, improved endothelial function, and anti-atherogenic effects. Edible oils containing omega-3 fatty acids were registered as functional ingredients in the Korea Health Functional Food Code. Although omega-3 fatty acids have been evaluated by the Korea Food and Drug Administration (KFDA) based on scientific evidence, periodic re-evaluation may be needed because emerging data related to omega-3 fatty acids have accumulated. Therefore, in this study, we re-evaluated scientific evidence for the effect of omega-3 fatty acids as a functional ingredient in health functional food on improvement of blood flow. A comprehensive literature search was conducted for collection of relevant human studies using the Medline and Cochrane, KISS, and IBIDS databases for the years 1955-2012. Search keywords were used by combination of terms related to omega-3 fatty acids and blood flow. The search was limited to human studies published in Korean, English, and Japanese. Using the KFDA's evidence based evaluation system for scientific evaluation of health claims, 112 human studies were identified and reviewed in order to evaluate the strength of the evidence supporting a relation between omega-3 fatty acids and blood flow. Among 112 studies, significant effects on improvement of blood flow were reported in 84 studies and the daily intake amount was ranged from 0.1 to 15 g. According to this methodology of systematic review, we concluded that there was possible evidence to support a relation between omega-3 fatty acid intake and blood flow. However, because inconsistent results have recently been reported, future studies should be monitored.

A Study on Perception and Nursing Activity for Patient Safety of Operating Room Nurses (수술실 간호사의 환자안전의식과 안전관리활동)

  • Park, So-Jeong;Choi, Eun-Hee;Lee, Kyeong-Soo;Chung, Kwi-Ae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.11
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    • pp.332-339
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    • 2016
  • This study aimed to investigate the awareness and performance of safety in operating room nurses. There were 161 operating room nurses from eight general hospitals included for analysis in this study. The data were analyzed with t-test, one-way ANOVA, correlation analysis, and Scheffe's test. The results show that their perception of patient safety was 3.33 out of a total of 5 points. Moreover, the score of safety management activity for patients in the operating room was 4.28 out of 5 points. As the perception of patient safety in operating room nurses was significantly correlated with their safety management activities, nurses with higher awareness of patient safety were found to have higher degree of performance of safety management activities. In conclusion, to improve safety management activities, open discussion about patient safety should be encouraged and periodic education regarding patient safety should be implemented for operating room nurses to increase the perception of patient safety.

Construction and Validation of Infection Control Practice Scale for Dental Hygienist (치과위생사의 감염관리 실천도 측정도구의 개발과 타당화)

  • Cho, Young-Sik;Jun, Bo-Hye;Choi, Young-Suk
    • Journal of dental hygiene science
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    • v.9 no.1
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    • pp.53-59
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    • 2009
  • Infection control is now recognized as an important quality indicator in dental health service setting. The purpose of this study was to develop and validate Dental Hygienist's Infection Control Practice Scale for quality management of dental health service in Korea. The data of 254 dental hygienists was subjected to exploratory factor analysis using SPSS 16.0 and confirmatory factor analysis using AMOS 16.0. The total items of preliminary scale were 21 items and 5 subscale. Principal component analysis was completed with Varimax rotation. The results show a change in factor structure from 5 factor solution to 4 factor solution. The confirmatory factor analysis confirmed the four subscales(Immunization and periodic tests, Clinical procedure, Handwashing, Personal protection) which have a total of 12 items. After the item deleted because factor loading was low, measured model was tested. The results of the measurement model indicated fit indices: $x^2$= 79.593(df = 38, 0 = 0.000), RMR = 0.045, GFI = 0.940, CFI = 0.904, AGFI = 0.896, NFI = 0.837, TLI = 0.861, RMSEA = 0.67. The squared correlation between four constructs were less than the average variance extracted(AVE) of four constructs. Multiple regression analysis was completed. Dependent variable was the perceived infection control practice by dental hygienist. Independent variables were four summated subscales(R = 0.552, $R^2$= 0.304, Adjusted $R^2$= 0.431, F = 25.813, p = 0.000). Unstandardized coefficients of three independent variables were statistically significant.

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EPIDEMIOLOGICAL EVALUATION OF PERIODONTAL STATUS IN KOREAN ADULTS (한국인의 치주조직상태에 관한 역학조사)

  • Han, Kyung-Yoon;Park, Jun-Bong;Chung, Jin-Hyung;Chung, Chong-Pyoung
    • Journal of Periodontal and Implant Science
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    • v.24 no.3
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    • pp.458-471
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    • 1994
  • To evaluate the periodontal status of Korean adults, 3,988 adults(20-69 years old) who lived in Kwangju, Chonnam, Taegu, and Kyungbuk districts were periodontally examined by plaque index(PI), calculus index(CI), gingival index(GI), periodontal disease index (PDI), and papillary bleeding index(PBI). The periodontal examination charts were grouped according to age and sex. And subsequently 200 periodontal examination charts in each age group were randomly selected according to sex. The differences of the indices among age groups and those between male and female in each age group were statistically analyzed by Chi-Square test. In PI, CI, GI, PDI, and PBI, there was no statistical significance in the difference between male and female in each age group(p>0.05). In male, PI of 60s age group($1.44{\pm}0.68$) was significantly higher than that of any age group(p<0.05), and in female PI of 20s age group($0.86{\pm}0.39$) was significantly lower than that of any other age group(p<0.05). CI of 60s age group in both male($1.67{\pm}0.70$) and female($1.63{\pm}0.91$) was significantly higher than that of any age group(p<0.05). GI of 20s age group in both male($0.85{\pm}0.66$) and female($0.67{\pm}0.60$) was significantly lower and GI of 60s age group in both male($1.37{\pm}0.60$) and female($1.44{\pm}0.84$) was higher than that of any age group(p<0.05). PDI in male was the lowest in 20s age group($0.70{\pm}0.73$), and was the highest in 60s age group($4.93{\pm}1.96$) (p<0.05). In female PDI of 20s age group($0.71{\pm}0.74$) was significantly lower than that of any age group(p<0.05). In male PBI of 20s age group($0.38{\pm}0.31$) was significantly lower than that of any age group(p<0.001). PBI in female was the lowest in 20s age group($0.35{\pm}0.30$) (p<0.001), and was the highest in 60s age group($1.09{\pm}0.76$) (p<0.05). The data insist that all the young populations of 20s age group should be interested in routine check for early diagnosis and prevention of periodontal disease, and a special education program of periodontal health care for young generation must be prepared, and the periodic recall check system for periodontal examination of middle age group must be supported by government.

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Study on the Measurement System for MIMO Channel Considering Urban Environment at Microwave Frequencies (도심 환경을 고려한 마이크로파 대역 MIMO 전파 채널 측정 시스템에 관한 연구)

  • Lim, Jae-Woo;Kwon, Se-Woong;Moon, Hyun-Wook;Park, Yoon-Hyun;Yoon, Young-Joong;Yook, Jong-Gwan;Jeong, Jin-Soub;Kim, Jong-Ho
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.18 no.10
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    • pp.1142-1149
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    • 2007
  • In this paper, the development of wideband MIMO channel sounder and a pilot measurement result is described for research on the multi antenna radio propagation characteristics considering urban environment at microwave frequencies. We developed $4{\times}4$ MIMO(BW:100 MHz) channel sounder using the high speed switching mechanism and periodic pseudo random binary signals method considering next generation mobile communication system. A pilot measurement campaign at the urban area of Bundang is presented for confirmation of system performance. From the analysis of measurement data, wideband path loss exponent of 3.7 and 8 GHz band is 1.79 and 1.76. Average RMS delay spread is 200 ns and 42 ns respectively. From the experiment results, operation of this measurement system is confirmed considering research for a coverage, SNR and channel capacity in urban environment at microwave frequencies.

Selecting the Optimal Method of Competition Index Computation for Major Coniferous Species in Korea (우리나라 주요 침엽수종의 최적 경쟁지수 모형 선정)

  • Lee, Jungho;Lee, Daesung;Seo, Yeongwan;Choi, Jungkee
    • Journal of Korean Society of Forest Science
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    • v.107 no.2
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    • pp.193-204
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    • 2018
  • This study was carried out to select the optimal method of competition index computation according to the competitor selection methods and distant-dependent competition index models, and to analyze the characteristics of competition indices in terms of thinning intensity and tree density targeting Pinus densiflora, Pinus koraiensis, and Larix kaempferi, which are the major coniferous species in Korea. Data was the re-investigated tree information from 240 permanent plots of 80 sites in the stands of P. densiflora, P. koraiensis, and L. kaempferi, which were located in the national forest of Gangwon and North Gyeongsang provinces. The number of subject trees with competition index calculated were 1126 trees for P. densiflora, 4093 trees for P. koraiensis, and 3399 trees for L. kaempferi. For the best competition index computation method, three kinds of competitor selection methods were considered: basal area factor, angle of height, angle of height to crown base. Also, six kinds of competition index models were compared: Lorimer, Martin-EK, Braathe, Heygi, Daniels, and Modified Daniels, which was developed in this study. Correlation coefficient was the best when the competitor selection method of basal area factor $4m^2/ha$ and the competition index model of Modified Daniels were used, and thus, it was selected as the best method for computing competition index. According to the best method by stand characteristics, competition index decreased in all species as thinning intensity was high and tree density was low.

Trend of the Changes in the Level of Blood Lead, Urinary Arsenic and Urinary Cadmium of children in Ulsan ; 3-year Follow-up Study (울산지역 어린이들의 혈중 연, 요중 비소 및 카드뮴 농도 변화추이 - 3년 추적조사)

  • Yoo, Cheol-In;Lee, Ji-Ho;Lee, Hun;Kim, Yang-Ho;Lee, Choong-Ryeol
    • Journal of Preventive Medicine and Public Health
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    • v.34 no.2
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    • pp.166-174
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    • 2001
  • Objectives : To obtain basic data on blood lead level and urinary level of arsenic and cadmium of children living near a petrochemical estate and a suburban area in Ulsan, Korea and to observe the trend of the changes. In the level of these metals in these children. Methods : The study subjects comprised 626 children living near a petrochemical estate and 299 children living in a suburban area of Ulsan. We analyzed the level of lead, arsenic and cadmium using atomic absorption spectrometer. Results : The mean levels of blood lead in children living near the petrochemical estate were $5.25{\mu}g/dl,\;5.24{\mu}g/dl,\;and\;7.24{\mu}g/dl$, and in the years 1997, 1999, and 2000, respectively, whereas those of children living in the suburban area were $3.81{\mu}g/dl,\;4.75{\mu}g/dl,\;and\;7.19{\mu}g/dl$ respectively. The mean levels of urinary arsenic in children living near the petrochemical estate were $4.57{\mu}g/g$ creatinine, $4.78{\mu}g/g$ creatinine, and $6.02{\mu}g/g$ creatinine in the year 1997, 1999, and 2000 respectively, whereas those of children living in suburban area were $2.35{\mu}g/g$ creatinine, $4.75{\mu}g/g$ creatinine, and $7.07{\mu}g/g$ creatinine, respectively. The mean levels of urinary cadmium in children living near the petrochemical estate were $1.15{\mu}g/g$ creatinine, $1.05{\mu}g/g$ creatinine, and $1.71{\mu}g/g$ creatinine in the year 1997, 1999, and 2000, respectively, whereas those of the children living in the suburban area were $0.74{\mu}g/g$ creatinine, $1.29{\mu}g/g$ creatinine, and $1.48{\mu}g/g$ creatinine, respectively. There were increasing trends in the level of blood lead, urinary arsenic and cadmium of children in Ulsan, and the differences in the level of these metals were disappearing between the children living in other areas year by year. Conclusions : These results suggest that the amount of exposure to lead, arsenic, and cadmium is increasing from year to year, and there is a need for periodic biological and atmospheric monitoring of these metals in Ulsan.

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Tracking Control using Disturbance Observer and ZPETC on LonWorks/IP Virtual Device Network (LonWorks/IP 가상 디바이스 네트워크에서 외란관측기와 ZPETC를 이용한 추종제어)

  • Song, Ki-Won
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.44 no.1
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    • pp.33-39
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    • 2007
  • LonWorks over IP (LonWorks/IP) virtual device network (VDN) is an integrated form of LonWorks device network and IP data network. LonWorks/IP VDN can offer ubiquitous access to the information on the factory floor and make it possible for the predictive and preventive maintenance on the factory floor. Timely response is inevitable for predictive and preventive maintenance on the factory floor under the real-time distributed control. The network induced uncertain time delay deteriorates the performance and stability of the real-time distributed control system on LonWorks/IP virtual device network. Therefore, in order to guarantee the stability and to improve the performance of the networked distributed control system the time-varying uncertain time delay needs to be compensated for. In this paper, under the real-time distributed control on LonWorks/IP VDN with uncertain time delay, a control scheme based on disturbance observer and ZPETC(Zero Phase Error Tracking Controller) phase lag compensator is proposed and tested through computer simulation. The result of the proposed control is compared with that of internal model controller (IMC) based on Smith predictor and disturbance observer. It is shown that the proposed control scheme is disturbance and noise tolerant and can significantly improve the stability and the tracking performance of the periodic reference. Therefore, the proposed control scheme is well suited for the distributed servo control for predictive maintenance on LonWorks/IP-based virtual device network with time-varying delay.

Systematic Review of the Effect of Glucosamine on Joint Health while Focused on the Evaluation of Claims for Health Functional Food (건강기능식품의 기능성을 중심으로 한 글루코사민의 관절건강 기능성에 대한 체계적 고찰)

  • Kim, Joohee;Kim, Ji Yeon;Kwak, Jin Sook;Paek, Ju Eun;Jeong, Sewon;Kwon, Oran
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.2
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    • pp.293-299
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    • 2014
  • Although the functional ingredient has been evaluated based on scientific evidence by the Ministry of Food and Drug Safety (MFDS), the levels of scientific evidence and consistency of the results might vary according to the emerging data. Therefore, a periodic re-evaluation may be needed in some functional ingredients. In this study, we re-evaluated the scientific evidence for the joint health of glucosamine as a functional ingredient in health functional food. Literature searches were conducted using Pubmed, Cochrane, KISS, and IBIDS databases with the search term of glucosamine in combination with osteoarthritis. The search was limited to human studies published in English, Korean and Japanese. Using the MFDS's evidence based evaluation system for scientific evaluation of health claims, 34 human studies were identified and reviewed in order to evaluate the strength of the evidence supporting the relation between glucosamine and joint health. Among the 34 studies, significant effects for joint health were reported in 28 studies, and their daily intake amount was 1.5 to 2 g. Eleven out of 34 studies were identified, excluding severe radiographic osteoarthritis, and ten from those eleven studies reported significant effects for joint health. Based on this systematic review, we concluded that there was possible evidence to support a relation between glucosamine intake and joint health.

Measurement of Respiratory Motion Signals for Respiratory Gating Radiation Therapy (호흡동조 방사선치료를 위한 호흡 움직임 신호 측정)

  • Chung, Jin-Beom;Chung, Won-Kyun;Kim, Yon-Lae;Lee, Jeong-Woo;Suh, Tae-Suk
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2005.04a
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    • pp.59-63
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    • 2005
  • Respiration motion causes movement of internal structures in the thorax and abdomen, making accurate delivery of radiation therapy to tumors in those areas a challenge. Accounting for such motion during treatment, therefore, has the potential to reduce margins drawn around the clinical target volume (CTV), resulting in a lower dose to normal tissues (e.g., lung and liver) and thus a lower risk of treatment induced complications. Among the techniques that explicitly account for intrafraction motion are breath-hold, respiration gating, and 4D or tumor-tracking techniques. Respiration gating methods periodically turn the beam on when the patient's respiration signal is in a certain part of the respiratory cycle (generally end-inhale or end-exhale). These techniques require acquisition of some form of respiration motion signal (infrared reflective markers, spirometry, strain gauge, thermistor, video tracking of chest outlines and fluoroscopic tracking of implanted markers are some of the techniques employed to date), which is assumed to be correlated with internal anatomy motion. In preliminary study for the respiratory gating radiation therapy, we performed to measurement of this respiration motion signal. In order to measure the respiratory motion signals of patient, respiration measurement system (RMS) was composed with three sensor (spirometer, thermistor, and belt transducer), 4 channel data acquisition system and mobile computer. For two patients, we performed to evaluation of respiratory cycle and shape with RMS. We observed under this system that respiratory cycle is generally periodic but asymmetric, with the majority of time spent. As expected, RMS traced patient's respiration each other well and be easily handled for application.

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