• Radiation Oncology Journal
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• v.11 no.1
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• pp.119-126
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• 1993

From 1988 to 1991, nineteen patients with unresectable localized pancreatic carcinoma were treated with radiotherapy and/or hyperthermia or in combination with chemotherapy. Radiation dose of 4500-5000 cGy with or without additional 500-1000 cGy was administered over 5 to 6 weeks to the pancreatic tumor area using 10 MV linear accelerator. Five of 19 patients were given chemotherapy, either neoadjuvant or maintenance setting with FAM regimen (5-FU, adriamycin and mitomycin C), which was repeated every 4 weeks for one year or until progression. Symptomatic palliation was achieved in 17 among 19 patients ($89{\%}$) and objective response (complete or partial response in CT finding) was achieved in 5 among 11 patients ($45{\%}$). The median survival time was 9 months and one-year survival rate, $32{\%}$. Local-regional failure was documented in 10 among 13 patients ($77{\%}$) and distant failures were found in the liver (3 patients) and carcinomatosis (2 patients). Prognostic significance of various factors such as age, sex, performance status, tumor location, stage, etc. were assessed. Any factors did not have the prognostic significance in univariate analysis. Treatment was well tolerated in most of the patients with only mild to moderate toxicity.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.1
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• pp.42-47
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• 2010

The pulse diagnosis is an important method in Oriental Medicine. Recently, there have been continuous attempts to replace the finger palpation by Oriental medical doctors (OMDs) by more objective tools based on machines, e.g., pulse analyzers. To improve the performance of the pulse analyzers, both the machine-appropriate interpretations for the pulse images appeared in the literature and the improvement in the repeatability and reproducibility of the measurement sensors are to be developed. As an attempt towards the transformation of the pulse images in terms of machine-appropriate language, in this work, we suggest an upgraded algorithm for the solid/deficient pulses, which are the two representative pulse images informing us how strong the pulse pressure is. It has been argued that one could determine the solid/deficient pulses by the maximum pulse pressure from pulse analyzers. However, by a clinical test, we found that the maximum pulse pressure alone is not sufficient to determine the solid/deficient pulses. In addition to the maximum pulse pressure, the mean pulse pressure averaged over for five different hold-down pressures(3-D MAC) is needed to improve the agreement with the OMD's decision for the solid/deficient pulse. We found that, among the data diagnosed with having either the solid pulse or deficient pulse by OMDs, the novel algorithm showed 86.0% diagnosis rate and 81.6% concordance rate.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2006.05a
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• pp.107-108
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• 2006

This paper shows the design optimization of the paper feeding mechanism under dynamic behavior by using commercial codes of RecurDyn/MTT2D and RecurDyn/AutoDesign which are developed by functionBay, Inc. A virtual mockup for dynamics analysis of the paper feeding mechanism is build on RecurDyn/MTT2D and is simulated. Flexible paper is represented as a series of rigid bars connected by revolute joints and rotational spring dampers. Paper is fed by a contact and friction mechanism on rollers or guides. The slip of the paper and nip force of rollers are measured to estimate the system performance. After a simulation, these performances are automatically send to RecurDyn/AutoDesign which is a sequential approximate optimization tool based on the response surface modeling. RecurDyn/AutoDesign makes the approximate objective function and computes the optimized design points of the design variables and gives them to analysis tool. And then the simulation is repeated with the updated design variables. These processes are repeated until finding a tolerable design optimization. In this paper, a paper feeding mechanism is introduced and it is optimized with the proposed algorithms.

• Journal of the Korean Vacuum Society
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• v.12 no.2
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• pp.130-135
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• 2003

Polycrystalline silicon thin films have been used for low cost thin film device application. However, it was very difficult to fabricate high performance poly-Si at a temperature lower than $600^{\circ}C$ for glass substrate because the crystallization process technologies like conventional solid phase crystallization (SPC) require the number of high temperature (600-$1000^{\circ}C$) process. The objective of this paper is to grow poly-Si on flexible substrate using a rapid thermal crystallization (RTC) of amorphous silicon (a-Si) layer and make the high temperature process possible on molybdenum substrate. For the high temperature poly-Si growth, we deposited the a-Si film on the molybdenum sheet having a thickness of 150 $\mu\textrm{m}$ as flexible and low cost substrate. For crystallization, the heat treatment was performed in a RTA system. The experimental results show the grain size larger than 0.5 $\mu\textrm{m}$ and conductivity of $10^{-5}$ S/cm. The a-Si was crystallized at $1050^{\circ}C$ within 3min and improved crystal volume fraction of 92 % by RTA. We have successfully achieved a field effect mobility over 67 $\textrm{cm}^2$/Vs.

• Korean Journal of Veterinary Research
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• v.50 no.1
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• pp.43-48
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• 2010

Animal disease surveillance system, defined as the continuous investigation of a given population to detect the occurrence of disease or infection for control purposes, has been key roles to assess the health status of an animal population and, more recently, in international trade of animal and animal products with regard to risk assessment. Especially, for a system aiming to determine whether or not a disease is present in a population sensitivity of the system should be maintained high enough not to miss an infected animal. Therefore, when planning the implementation of surveillance system a number of factors that affecting surveillance sensitivity should be taken into account. Of these parameters sample size is of important, and different approaches are used to calculate sample size, usually depending on the objective of surveillance systems. The purpose of this study was to evaluate the sensitivity of the current national serological surveillance programs for four selected bovine diseases assuming a specified sampling plan, to examine factors affecting the probability of detection, and to provide sample sizes required for achieving surveillance goal of detecting at least an infection in a given population. Our results showed that, for example, detecting low level of prevalence (0.2% for bovine tuberculosis) requires selection of all animals per typical Korean cattle farm (n = 17), and thus risk-based target surveillance for high risk groups can be an alternative strategy to increase sensitivity while not increasing overall sampling efforts. The minimum sample size required for detecting at least one positive animal was sharply increased as the disease prevalence is low. More importantly, high reliability of prevalence estimation was expected with increased sampling fraction even when zero-infected animal was identified. The effect of sample size is also discussed in terms of the maximum prevalence when zero-infected animals were identified and on the probability of failure to detect an infection. We suggest that for many serological surveillance systems, diagnostic performance of the testing method, sample size, prevalence, population size, and statistical confidence need to be considered to correctly interpret results of the system.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.36 no.12
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• pp.1599-1604
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• 2012

In general, internal defects, such as shrinkage in casting, cause stress concentration and can be a starting point for cracks. Therefore, it is important to understand the effects of internal defects on the mechanical properties including the impact behavior. This study aim is to evaluate the effects of internal casting defects on the impact performance of Al-alloy castings. Both an experimental method and computational analysis were used to achieve the research objective. The internal defects in the casting were scanned using an industrial CT scanner, and their shape was simplified using ellipsoidal primitives for impact analysis. The good agreement between the experimental and computer simulation results verified the reliability of the proposed computational method for the FEA of casting components with internal defects.

• Therapeutic Science for Rehabilitation
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• v.4 no.1
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• pp.29-38
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• 2015

Objective : The purpose of the study is to propose the treatment methods for problem of handwriting, micrographia in Parkinsons disease. Methods : For this purpose, foreign literatures on the subjects with Parkinsons disease was researched. Results : The results of this review is summarized as follows. The treatment methods for micrographia were applied to external cue and feedback among motor learning strategies in order to improve motor initiation. The external cues included visual, auditory, and verbal stimulations, and feedback strategy was visual stimulation. For writing with external cue or visual feedback, result in expanding the size of the letters in addition, writing task performance is maintained for a short period without those. Conclusion : Further studies are needed to examine the strategy maintained effect for long periods.

• Korean Journal of Food Science and Technology
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• v.40 no.6
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• pp.611-620
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• 2008

The principal objective of this study was to assess the effects of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) extracted from egg yolk on the oxidation of tocopherol-stripped canola oil and its browning, as well as their content changes during 12 hr of heating at $180^{\circ}C$. PC and/ or PE contents in the oil were measured at 200, 500, 1,000, or 2,000 ppm. PL contents in the oil and oil browning were determined by high performance liquid chromatography (HPLC) and spectrophotometry, respectively. The oil oxidation was evaluated by the combination of fatty acid composition, conjugated dienoic acid content, and p-anisidine value. PC was degraded at a slower rate than PE during heating and the co-presence of PE reduced its rate of degradation. PE increased oil browning more profoundly than PC did. PC significantly reduced oil oxidation during heating; however, we noted a possible antagonism between PE and PC in reducing the oil oxidation. Egg yolk PC was a better antioxidant in oil oxidation during heating.

• Journal of the Korean Society of Industry Convergence
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• v.2 no.2
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• pp.11-21
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• 1999

This objective of this paper is to investigate the evaluation and indiction of human thermal comfort in building environment. The issue of defining the boundaries of acceptable thermal comfort conditions in buildings and urban may have significant implication for building design and also may have urban design by climate considerations. And then it is to apply the thermal comfort condition to environmental design by using passive methods in Korea. Since 1920. architects have conducted studies to measure thermal comfort in houses under hot and humid conditions, while industrial hygienists have studied the effects of temperature and humidity on the performance of factory workers. Thermal comfort can be influenced by many variables. This paper conducted to review the previous researches and the human heat balance equation, and to analyse in order to reveal the meaning and usage of the thermal comfort index in two traditional essays, Fanger's PMV and Gagge's ET* Their comfort indexes compared with each other. They were based on human heat balance equation and psychological and physiological responses in the laboratory tests. The researchers and the architectural engineers using thermal comfort index shall be careful in decided the use of indexes and be necessary to recognize the value concept of the design criteria for thermal comfort. Therefore, The opinion of the authors is that different comfort standards have to apply for each building and urban with different climatic conditions.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.25 no.6_1
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• pp.545-555
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• 2007

3D buildings are the most prominent feature comprising urban scene. A few of mega-cities in the globe are virtually reconstructed in photo-realistic 3D models, which becomes accessible by the public through the state-of-the-art online mapping services. A lot of research efforts have been made to develop automatic reconstruction technique of large-scale 3D building models from remotely sensed data. However, existing methods still produce irregular building polygons due to errors induced partly by uncalibrated sensor system, scene complexity and partly inappropriate sensor resolution to observed object scales. Thus, a geometric regularization technique is urgently required to rectify such irregular building polygons that are quickly captured from low sensory data. This paper aims to develop a new method for regularizing noise building outlines extracted from airborne LiDAR data, and to evaluate its performance in comparison with existing methods. These include Douglas-Peucker's polyline simplication, total least-squared adjustment, model hypothesis-verification, and rule-based rectification. Based on Minimum Description Length (MDL) principal, a new objective function, Geometric Minimum Description Length (GMDL), to regularize geometric noises is introduced to enhance the repetition of identical line directionality, regular angle transition and to minimize the number of vertices used. After generating hypothetical regularized models, a global optimum of the geometric regularity is achieved by verifying the entire solution space. A comparative evaluation of the proposed geometric regulator is conducted using both simulated and real building vectors with various levels of noise. The results show that the GMDL outperforms the selected existing algorithms at the most of noise levels.